Published in Nat Rev Mol Cell Biol on May 01, 2006
Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1. Nat Genet (2009) 8.44
Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus. Nature (2009) 5.96
Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators. EMBO J (2008) 4.28
Mutations in cohesin complex members SMC3 and SMC1A cause a mild variant of cornelia de Lange syndrome with predominant mental retardation. Am J Hum Genet (2007) 4.20
Targeting X chromosomes for repression. Curr Opin Genet Dev (2010) 3.36
ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity. Cell (2008) 2.94
Transcriptional dysregulation in NIPBL and cohesin mutant human cells. PLoS Biol (2009) 2.89
Identification of cis-acting sites for condensin loading onto budding yeast chromosomes. Genes Dev (2008) 2.87
Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons. Dev Cell (2008) 2.82
Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome. Chromosoma (2007) 2.73
Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes. Nucleic Acids Res (2008) 2.70
All tangled up: how cells direct, manage and exploit topoisomerase function. Nat Rev Mol Cell Biol (2011) 2.66
piggyBac-based mosaic screen identifies a postmitotic function for cohesin in regulating developmental axon pruning. Dev Cell (2008) 2.56
Recruitment of SMC by ParB-parS organizes the origin region and promotes efficient chromosome segregation. Cell (2009) 2.56
Condensin and cohesin complexity: the expanding repertoire of functions. Nat Rev Genet (2010) 2.49
Condensins: universal organizers of chromosomes with diverse functions. Genes Dev (2012) 2.40
Human mitotic chromosomes consist predominantly of irregularly folded nucleosome fibres without a 30-nm chromatin structure. EMBO J (2012) 2.17
High-resolution mapping of the spatial organization of a bacterial chromosome. Science (2013) 2.17
Cohesin: genomic insights into controlling gene transcription and development. Curr Opin Genet Dev (2011) 2.12
Clearing the way for mitosis: is cohesin a target? Nat Rev Mol Cell Biol (2009) 1.88
Epigenetic regulation of condensin-mediated genome organization during the cell cycle and upon DNA damage through histone H3 lysine 56 acetylation. Mol Cell (2012) 1.85
Chromatin higher-order structure and dynamics. Cold Spring Harb Perspect Biol (2010) 1.81
Condensin regulates the stiffness of vertebrate centromeres. Mol Biol Cell (2009) 1.81
Centromeres: unique chromatin structures that drive chromosome segregation. Nat Rev Mol Cell Biol (2011) 1.80
Organization and segregation of bacterial chromosomes. Nat Rev Genet (2013) 1.76
Micromechanical studies of mitotic chromosomes. Chromosome Res (2008) 1.70
Cohesin and human disease. Annu Rev Genomics Hum Genet (2008) 1.68
Condensin: Architect of mitotic chromosomes. Chromosome Res (2009) 1.67
Cohesin, condensin, and the intramolecular centromere loop together generate the mitotic chromatin spring. J Cell Biol (2011) 1.66
Centromeric localization of dispersed Pol III genes in fission yeast. Mol Biol Cell (2009) 1.60
Listeria monocytogenes surface proteins: from genome predictions to function. Microbiol Mol Biol Rev (2007) 1.59
Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton. J Cell Sci (2009) 1.58
Microcephalin/MCPH1 associates with the Condensin II complex to function in homologous recombination repair. J Biol Chem (2008) 1.52
High-sensitivity detection and quantitative analysis of native protein-protein interactions and multiprotein complexes by flow cytometry. Sci STKE (2007) 1.51
The TBP-PP2A mitotic complex bookmarks genes by preventing condensin action. Nat Cell Biol (2008) 1.50
The SMC condensin complex is required for origin segregation in Bacillus subtilis. Curr Biol (2014) 1.49
Shugoshin-2 is essential for the completion of meiosis but not for mitotic cell division in mice. Genes Dev (2008) 1.49
RAD21L, a novel cohesin subunit implicated in linking homologous chromosomes in mammalian meiosis. J Cell Biol (2011) 1.46
On the molecular etiology of Cornelia de Lange syndrome. Ann N Y Acad Sci (2009) 1.44
Escherichia coli condensin MukB stimulates topoisomerase IV activity by a direct physical interaction. Proc Natl Acad Sci U S A (2010) 1.41
In vivo analysis of cohesin architecture using FRET in the budding yeast Saccharomyces cerevisiae. EMBO J (2007) 1.40
Shugoshin-PP2A counteracts casein-kinase-1-dependent cleavage of Rec8 by separase. Nat Cell Biol (2010) 1.40
The 3D Genome as Moderator of Chromosomal Communication. Cell (2016) 1.39
Mitotic spindle form and function. Genetics (2012) 1.38
ParB spreading requires DNA bridging. Genes Dev (2014) 1.38
RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity. PLoS One (2011) 1.38
Functional links between Drosophila Nipped-B and cohesin in somatic and meiotic cells. Chromosoma (2007) 1.35
Cdc7-Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts. Genes Dev (2008) 1.34
Chromatin condensation via the condensin II complex is required for peripheral T-cell quiescence. EMBO J (2010) 1.32
Condensin II resolves chromosomal associations to enable anaphase I segregation in Drosophila male meiosis. PLoS Genet (2008) 1.31
Age-related aneuploidy through cohesion exhaustion. EMBO Rep (2012) 1.31
The Smc complexes in DNA damage response. Cell Biosci (2012) 1.31
Towards building a chromosome segregation machine. Nature (2010) 1.25
Sister acts: coordinating DNA replication and cohesion establishment. Genes Dev (2010) 1.24
Condensin II promotes the formation of chromosome territories by inducing axial compaction of polyploid interphase chromosomes. PLoS Genet (2012) 1.24
Architecture of the Smc5/6 Complex of Saccharomyces cerevisiae Reveals a Unique Interaction between the Nse5-6 Subcomplex and the Hinge Regions of Smc5 and Smc6. J Biol Chem (2009) 1.23
Meiotic cohesin complexes are essential for the formation of the axial element in mice. J Cell Biol (2012) 1.23
Reconstitution and subunit geometry of human condensin complexes. EMBO J (2007) 1.22
The Drosophila cohesin subunit Rad21 is a trithorax group (trxG) protein. Proc Natl Acad Sci U S A (2008) 1.22
A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection. EMBO J (2012) 1.21
Chromosomes without a 30-nm chromatin fiber. Nucleus (2012) 1.21
Evolutionary diversity and developmental regulation of X-chromosome inactivation. Hum Genet (2011) 1.20
Molecular analysis of mitotic chromosome condensation using a quantitative time-resolved fluorescence microscopy assay. Proc Natl Acad Sci U S A (2006) 1.18
An asymmetric SMC-kleisin bridge in prokaryotic condensin. Nat Struct Mol Biol (2013) 1.17
Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins. Nucleic Acids Res (2010) 1.17
Cooperation of sumoylated chromosomal proteins in rDNA maintenance. PLoS Genet (2008) 1.16
Disengaging the Smc3/kleisin interface releases cohesin from Drosophila chromosomes during interphase and mitosis. EMBO J (2013) 1.16
Centromeric heterochromatin: the primordial segregation machine. Annu Rev Genet (2014) 1.16
Packaging the genome: the structure of mitotic chromosomes. J Biochem (2007) 1.15
Pericentric chromatin loops function as a nonlinear spring in mitotic force balance. J Cell Biol (2013) 1.15
Mitotic bookmarking of formerly active genes: keeping epigenetic memories from fading. Cell Cycle (2009) 1.15
Cohesin subunit SMC1 associates with mitotic microtubules at the spindle pole. Proc Natl Acad Sci U S A (2008) 1.15
BslA, the S-layer adhesin of B. anthracis, is a virulence factor for anthrax pathogenesis. Mol Microbiol (2009) 1.14
Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor. Nature (2016) 1.13
In vitro nuclear interactome of the HIV-1 Tat protein. Retrovirology (2009) 1.13
Identification of cellular proteins that interact with the adeno-associated virus rep protein. J Virol (2008) 1.12
Inter-individual differences in CpG methylation at D4Z4 correlate with clinical variability in FSHD1 and FSHD2. Hum Mol Genet (2014) 1.11
Chromatin as dynamic 10-nm fibers. Chromosoma (2014) 1.11
Cohesin association to replication sites depends on rad50 and promotes fork restart. Mol Cell (2012) 1.10
Three distinct stages of apoptotic nuclear condensation revealed by time-lapse imaging, biochemical and electron microscopy analysis of cell-free apoptosis. Exp Cell Res (2007) 1.10
Cohesins repress Kaposi's sarcoma-associated herpesvirus immediate early gene transcription during latency. J Virol (2012) 1.08
Displacement and re-accumulation of centromeric cohesin during transient pre-anaphase centromere splitting. Chromosoma (2007) 1.08
Molecular evolution of type VI intermediate filament proteins. BMC Evol Biol (2007) 1.08
Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol (2013) 1.07
The ancestral role of ATP hydrolysis in type II topoisomerases: prevention of DNA double-strand breaks. Nucleic Acids Res (2011) 1.07
Spectrum and consequences of SMC1A mutations: the unexpected involvement of a core component of cohesin in human disease. Hum Mutat (2010) 1.06
Molecular and genetic analysis of condensin function in vertebrate cells. Mol Biol Cell (2008) 1.06
Diverse developmental disorders from the one ring: distinct molecular pathways underlie the cohesinopathies. Front Genet (2012) 1.06
SMC condensin entraps chromosomal DNA by an ATP hydrolysis dependent loading mechanism in Bacillus subtilis. Elife (2015) 1.06
Mechanics of DNA bridging by bacterial condensin MukBEF in vitro and in singulo. EMBO J (2010) 1.04
SMC3 knockdown triggers genomic instability and p53-dependent apoptosis in human and zebrafish cells. Mol Cancer (2006) 1.03
Differential requirements of a mitotic acetyltransferase in somatic and germ line cells. Dev Biol (2008) 1.03
DNA repair and genome maintenance in Bacillus subtilis. Microbiol Mol Biol Rev (2012) 1.03
Cell cycle control of Kaposi's sarcoma-associated herpesvirus latency transcription by CTCF-cohesin interactions. J Virol (2009) 1.03
Condensin I associates with structural and gene regulatory regions in vertebrate chromosomes. Nat Commun (2013) 1.02
Condensin I binds chromatin early in prophase and displays a highly dynamic association with Drosophila mitotic chromosomes. Chromosoma (2007) 1.02
Structural and functional insights into the roles of the Mms21 subunit of the Smc5/6 complex. Mol Cell (2009) 1.01
Roles of vertebrate Smc5 in sister chromatid cohesion and homologous recombinational repair. Mol Cell Biol (2011) 1.01
Critical role of RecN in recombinational DNA repair and survival of Helicobacter pylori. Infect Immun (2007) 0.99
IP-FCM measures physiologic protein-protein interactions modulated by signal transduction and small-molecule drug inhibition. PLoS One (2012) 0.98