Published in Yeast on April 30, 2006
Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry. Proc Natl Acad Sci U S A (2009) 4.13
Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology. Mol Biol Cell (2009) 2.17
Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae. Genetics (2012) 1.98
Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling. J Biol Chem (2009) 1.63
Neurolipidomics: challenges and developments. Front Biosci (2007) 1.29
Lipid particles/droplets of the yeast Saccharomyces cerevisiae revisited: lipidome meets proteome. Biochim Biophys Acta (2011) 1.22
Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast. Mol Biol Cell (2008) 1.10
Roles for sphingolipids in Saccharomyces cerevisiae. Adv Exp Med Biol (2010) 1.08
A versatile ultra-high performance LC-MS method for lipid profiling. J Chromatogr B Analyt Technol Biomed Life Sci (2014) 1.07
Characterization of substrate preference for Slc1p and Cst26p in Saccharomyces cerevisiae using lipidomic approaches and an LPAAT activity assay. PLoS One (2010) 0.98
Role of unsaturated lipid and ergosterol in ethanol tolerance of model yeast biomembranes. Biophys J (2012) 0.94
Lipidomic profiling of Saccharomyces cerevisiae and Zygosaccharomyces bailii reveals critical changes in lipid composition in response to acetic acid stress. PLoS One (2013) 0.91
Ethanol production and maximum cell growth are highly correlated with membrane lipid composition during fermentation as determined by lipidomic analysis of 22 Saccharomyces cerevisiae strains. Appl Environ Microbiol (2012) 0.90
The yeast sphingolipid signaling landscape. Chem Phys Lipids (2013) 0.90
Lipidomics of intact mitochondria by MALDI-TOF/MS. J Lipid Res (2012) 0.90
Two pathways of sphingolipid biosynthesis are separated in the yeast Pichia pastoris. J Biol Chem (2011) 0.89
A review of lipidomic technologies applicable to sphingolipidomics and their relevant applications. Eur J Lipid Sci Technol (2009) 0.88
Identification of a sphingolipid α-glucuronosyltransferase that is essential for pollen function in Arabidopsis. Plant Cell (2014) 0.87
Gel domains in the plasma membrane of Saccharomyces cerevisiae: highly ordered, ergosterol-free, and sphingolipid-enriched lipid rafts. J Biol Chem (2010) 0.84
A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis. PLoS Genet (2011) 0.84
YPR139c/LOA1 encodes a novel lysophosphatidic acid acyltransferase associated with lipid droplets and involved in TAG homeostasis. Mol Biol Cell (2011) 0.84
Sphingolipids and ceramides in human aqueous humor. Mol Vis (2013) 0.82
Fermentation temperature modulates phosphatidylethanolamine and phosphatidylinositol levels in the cell membrane of Saccharomyces cerevisiae. Appl Environ Microbiol (2013) 0.81
An assessment of growth media enrichment on lipid metabolome and the concurrent phenotypic properties of Candida albicans. PLoS One (2014) 0.79
Comparative Lipidomic Profiling of S. cerevisiae and Four Other Hemiascomycetous Yeasts. Metabolites (2012) 0.79
Open Field Study of Some Zea mays Hybrids, Lipid Compounds and Fumonisins Accumulation. Toxins (Basel) (2015) 0.78
Identification of the galactosyltransferase of Cryptococcus neoformans involved in the biosynthesis of basidiomycete-type glycosylinositolphosphoceramide. Glycobiology (2013) 0.76
Four Acyltransferases Uniquely Contribute to Phospholipid Heterogeneity in Saccharomyces cerevisiae. Lipid Insights (2016) 0.75
Budding Yeast: An Ideal Backdrop for In vivo Lipid Biochemistry. Front Cell Dev Biol (2017) 0.75
Sphingolipidomics: An Important Mechanistic Tool for Studying Fungal Pathogens. Front Microbiol (2016) 0.75
Med15B regulates acid stress response and tolerance in Candida glabrata. Appl Environ Microbiol (2017) 0.75
Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin. Nature (2002) 4.03
Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle. Science (2002) 3.68
Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J Biol Chem (2010) 3.45
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway. J Cell Biol (2005) 2.97
Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast. J Cell Biol (2008) 2.85
Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking. Nature (2004) 2.81
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. J Clin Invest (2011) 2.68
Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides. J Virol (2008) 2.43
Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron (2002) 2.21
Chondroitin fragments are odorants that trigger fear behavior in fish. Curr Biol (2012) 2.20
ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Igamma. J Cell Biol (2003) 2.19
Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology. Mol Biol Cell (2009) 2.17
Salmonella modulates vesicular traffic by altering phosphoinositide metabolism. Science (2004) 2.06
Inhibitory effect of dietary lipids on chaperone-mediated autophagy. Proc Natl Acad Sci U S A (2012) 1.97
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. Immunity (2012) 1.96
Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses. Proc Natl Acad Sci U S A (2004) 1.84
A role for phosphatidic acid in the formation of "supersized" lipid droplets. PLoS Genet (2011) 1.69
Phosphatidic acid is a pH biosensor that links membrane biogenesis to metabolism. Science (2010) 1.64
Mitochondrial cardiolipin involved in outer-membrane protein biogenesis: implications for Barth syndrome. Curr Biol (2009) 1.62
Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer. Nature (2014) 1.60
Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis. PLoS Biol (2011) 1.56
The phospholipase D1 pathway modulates macroautophagy. Nat Commun (2010) 1.56
Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome. Proc Natl Acad Sci U S A (2008) 1.54
Comparative lipidomic analysis of mouse and human brain with Alzheimer disease. J Biol Chem (2011) 1.51
Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. J Neurosci (2010) 1.49
Sensitive profiling of chemically diverse bioactive lipids. J Lipid Res (2007) 1.45
Arabidopsis lipins mediate eukaryotic pathway of lipid metabolism and cope critically with phosphate starvation. Proc Natl Acad Sci U S A (2009) 1.44
PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity. J Cell Biol (2012) 1.41
The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis. J Cell Biol (2008) 1.32
Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation. PLoS Genet (2011) 1.30
Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles. Proc Natl Acad Sci U S A (2003) 1.28
Toward one step analysis of cellular lipidomes using liquid chromatography coupled with mass spectrometry: application to Saccharomyces cerevisiae and Schizosaccharomyces pombe lipidomics. Mol Biosyst (2010) 1.28
Triacylglycerol utilization is required for regrowth of in vitro hypoxic nonreplicating Mycobacterium bovis bacillus Calmette-Guerin. J Bacteriol (2009) 1.25
Induction of autophagy by palmitic acid via protein kinase C-mediated signaling pathway independent of mTOR (mammalian target of rapamycin). J Biol Chem (2012) 1.19
Meibum lipid composition in Asians with dry eye disease. PLoS One (2011) 1.16
A small molecule fusion inhibitor of dengue virus. Antiviral Res (2009) 1.16
Molecular characterization of seipin and its mutants: implications for seipin in triacylglycerol synthesis. J Lipid Res (2011) 1.14
Comparative plasma lipidome between human and cynomolgus monkey: are plasma polar lipids good biomarkers for diabetic monkeys? PLoS One (2011) 1.14
Non-targeted profiling of lipids during kainate-induced neuronal injury. FASEB J (2006) 1.13
Yeast lipid analysis and quantification by mass spectrometry. Methods Enzymol (2010) 1.13
Membrane lipids as signaling molecules. Curr Opin Lipidol (2007) 1.12
Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast. Mol Biol Cell (2008) 1.10
Towards ontology-driven navigation of the lipid bibliosphere. BMC Bioinformatics (2008) 1.10
Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling. J Cell Biol (2014) 1.10
Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities. J Am Chem Soc (2010) 1.09
The synaptojanin-like protein Inp53/Sjl3 functions with clathrin in a yeast TGN-to-endosome pathway distinct from the GGA protein-dependent pathway. Mol Biol Cell (2003) 1.08
A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion. PLoS Pathog (2013) 1.05
Fenretinide prevents lipid-induced insulin resistance by blocking ceramide biosynthesis. J Biol Chem (2012) 1.05
U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication. Antiviral Res (2011) 1.04
Extensive characterization of human tear fluid collected using different techniques unravels the presence of novel lipid amphiphiles. J Lipid Res (2013) 1.03
Emodin inhibits tumor cell adhesion through disruption of the membrane lipid Raft-associated integrin signaling pathway. Cancer Res (2006) 1.03
XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis. J Immunol (2009) 1.02
Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans. Proc Natl Acad Sci U S A (2013) 1.02
Biochemical membrane lipidomics during Drosophila development. Dev Cell (2012) 1.02
Structural and biological diversity of lipopolysaccharides from Burkholderia pseudomallei and Burkholderia thailandensis. Clin Vaccine Immunol (2009) 1.01
Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids. Nat Med (2012) 1.00
A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila. Autophagy (2009) 1.00
PGC-1α improves glucose homeostasis in skeletal muscle in an activity-dependent manner. Diabetes (2012) 0.99
Derivatization-independent cholesterol analysis in crude lipid extracts by liquid chromatography/mass spectrometry: applications to a rabbit model for atherosclerosis. J Chromatogr A (2011) 0.99
Mycolic acids as diagnostic markers for tuberculosis case detection in humans and drug efficacy in mice. EMBO Mol Med (2011) 0.99
Characterization of substrate preference for Slc1p and Cst26p in Saccharomyces cerevisiae using lipidomic approaches and an LPAAT activity assay. PLoS One (2010) 0.98
The membrane stress response buffers lethal effects of lipid disequilibrium by reprogramming the protein homeostasis network. Mol Cell (2012) 0.97
Lipid pathway alterations in Parkinson's disease primary visual cortex. PLoS One (2011) 0.96
Lipid droplet-associated proteins are involved in the biosynthesis and hydrolysis of triacylglycerol in Mycobacterium bovis bacillus Calmette-Guerin. J Biol Chem (2010) 0.96
Peculiarities of host cholesterol transport to the unique intracellular vacuole containing Toxoplasma. Traffic (2005) 0.95
Cdk5/p25-induced cytosolic PLA2-mediated lysophosphatidylcholine production regulates neuroinflammation and triggers neurodegeneration. J Neurosci (2012) 0.95
Specific inhibition of p25/Cdk5 activity by the Cdk5 inhibitory peptide reduces neurodegeneration in vivo. J Neurosci (2013) 0.92
Caspase-dependent and -independent lipotoxic cell-death pathways in fission yeast. J Cell Sci (2008) 0.92
N-Octanoylhomoserine lactone signalling mediated by the BpsI-BpsR quorum sensing system plays a major role in biofilm formation of Burkholderia pseudomallei. Microbiology (2011) 0.91
Rapid and sensitive profiling of tear wax ester species using high performance liquid chromatography coupled with tandem mass spectrometry. J Chromatogr A (2013) 0.91
Mitochondrial changes in ageing Caenorhabditis elegans--what do we learn from superoxide dismutase knockouts? PLoS One (2011) 0.90
The stem region of premembrane protein plays an important role in the virus surface protein rearrangement during dengue maturation. J Biol Chem (2012) 0.89
APOE genotype results in differential effects on the peripheral clearance of amyloid-beta42 in APOE knock-in and knock-out mice. J Alzheimers Dis (2010) 0.88
Evidence that selective changes in the lipid composition of raft-membranes occur during respiratory syncytial virus infection. Virology (2009) 0.87
A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance. Metab Eng (2011) 0.87
Docosapentaenoic acid (DPA) is a critical determinant of cubic membrane formation in amoeba Chaos mitochondria. FASEB J (2009) 0.85
Implications for lipids during replication of enveloped viruses. Chem Phys Lipids (2010) 0.85
Lipidomic analyses of the mouse brain after antidepressant treatment: evidence for endogenous release of long-chain fatty acids? Int J Neuropsychopharmacol (2009) 0.85
Transcriptomic and lipidomic profiles of glycerolipids during Arabidopsis flower development. New Phytol (2014) 0.85
Ablation of dihydroceramide desaturase confers resistance to etoposide-induced apoptosis in vitro. PLoS One (2012) 0.85
A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis. PLoS Genet (2011) 0.84
Lipidomic analysis of human tear fluid reveals structure-specific lipid alterations in dry eye syndrome. J Lipid Res (2013) 0.84
InsP3-mediated intracellular calcium signalling is altered by expression of synaptojanin-1. Biochem J (2004) 0.83
Sialic acid linkage in glycosphingolipids is a molecular correlate for trafficking and delivery of extracellular cargo. Traffic (2013) 0.82
Click-based synthesis and proteomic profiling of lipstatin analogues. Chem Commun (Camb) (2010) 0.82
Profiling brain and plasma lipids in human APOE epsilon2, epsilon3, and epsilon4 knock-in mice using electrospray ionization mass spectrometry. J Alzheimers Dis (2010) 0.82
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction. Biochimie (2012) 0.82
The size and phospholipid composition of lipid droplets can influence their proteome. Biochem Biophys Res Commun (2011) 0.81
Lipidomic "deep profiling": an enhanced workflow to reveal new molecular species of signaling lipids. Anal Chem (2014) 0.81
Lipidomics and genomics of Mycobacterium tuberculosis reveal lineage-specific trends in mycolic acid biosynthesis. Microbiologyopen (2014) 0.80
Neonatal overnutrition in mice exacerbates high-fat diet-induced metabolic perturbations. J Endocrinol (2013) 0.80
The fusogenic lipid phosphatidic acid promotes the biogenesis of mitochondrial outer membrane protein Ugo1. J Cell Biol (2015) 0.80
LipidGO: database for lipid-related GO terms and applications. Bioinformatics (2013) 0.80
Lipidomic study of intracellular Singapore grouper iridovirus. Virology (2010) 0.80
Identification and characterization of the lipid-binding property of GrlR, a locus of enterocyte effacement regulator. Biochem J (2009) 0.80
Targeting lipid esterases in mycobacteria grown under different physiological conditions using activity-based profiling with tetrahydrolipstatin (THL). Mol Cell Proteomics (2013) 0.79
Abc3-mediated efflux of an endogenous digoxin-like steroidal glycoside by Magnaporthe oryzae is necessary for host invasion during blast disease. PLoS Pathog (2012) 0.79
The identification of antioxidants in dark soy sauce. Free Radic Res (2007) 0.79
Expression, activity, and role of serine palmitoyltransferase in the rat hippocampus after kainate injury. J Neurosci Res (2007) 0.79
Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ε3 and ε4 knock-in mice. Neurobiol Aging (2013) 0.79