Published in Antiviral Res on November 29, 2011
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Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking. Nature (2004) 2.81
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. J Clin Invest (2011) 2.68
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Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology. Mol Biol Cell (2009) 2.17
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Salmonella modulates vesicular traffic by altering phosphoinositide metabolism. Science (2004) 2.06
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The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. Immunity (2012) 1.96
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Host gene expression profiling of dengue virus infection in cell lines and patients. PLoS Negl Trop Dis (2007) 1.86
Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites. J Cell Biol (2011) 1.84
Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses. Proc Natl Acad Sci U S A (2004) 1.84
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Inhibition of flavivirus infections by antisense oligomers specifically suppressing viral translation and RNA replication. J Virol (2005) 1.75
High-throughput assays using a luciferase-expressing replicon, virus-like particles, and full-length virus for West Nile virus drug discovery. Antimicrob Agents Chemother (2005) 1.73
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Triaryl pyrazoline compound inhibits flavivirus RNA replication. Antimicrob Agents Chemother (2006) 1.72
A role for phosphatidic acid in the formation of "supersized" lipid droplets. PLoS Genet (2011) 1.69
Immunoassay targeting nonstructural protein 5 to differentiate West Nile virus infection from dengue and St. Louis encephalitis virus infections and from flavivirus vaccination. J Clin Microbiol (2003) 1.65
Phosphatidic acid is a pH biosensor that links membrane biogenesis to metabolism. Science (2010) 1.64
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Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis. PLoS Biol (2011) 1.56
The phospholipase D1 pathway modulates macroautophagy. Nat Commun (2010) 1.56
West Nile virus infection of Drosophila melanogaster induces a protective RNAi response. Virology (2008) 1.56
Interaction between the cellular protein eEF1A and the 3'-terminal stem-loop of West Nile virus genomic RNA facilitates viral minus-strand RNA synthesis. J Virol (2007) 1.56
Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome. Proc Natl Acad Sci U S A (2008) 1.54
RNA structures required for production of subgenomic flavivirus RNA. J Virol (2010) 1.52
Comparative lipidomic analysis of mouse and human brain with Alzheimer disease. J Biol Chem (2011) 1.51
Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. J Neurosci (2010) 1.49
Distinct RNA elements confer specificity to flavivirus RNA cap methylation events. J Virol (2007) 1.48
Oxidation of 7,8-dihydro-8-oxoguanine affords lesions that are potent sources of replication errors in vivo. Biochemistry (2002) 1.48
Role of the mutant spectrum in adaptation and replication of West Nile virus. J Gen Virol (2007) 1.46
Sensitive profiling of chemically diverse bioactive lipids. J Lipid Res (2007) 1.45
Tetracycline-inducible packaging cell line for production of flavivirus replicon particles. J Virol (2004) 1.44
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West Nile virus methyltransferase catalyzes two methylations of the viral RNA cap through a substrate-repositioning mechanism. J Virol (2008) 1.44
Arabidopsis lipins mediate eukaryotic pathway of lipid metabolism and cope critically with phosphate starvation. Proc Natl Acad Sci U S A (2009) 1.44
The flavivirus-conserved penta-nucleotide in the 3' stem-loop of the West Nile virus genome requires a specific sequence and structure for RNA synthesis, but not for viral translation. Virology (2005) 1.43
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Dengue virus serotype infection specifies the activation of the unfolded protein response. Virol J (2007) 1.41
PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity. J Cell Biol (2012) 1.41
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A mouse cell-adapted NS4B mutation attenuates West Nile virus RNA synthesis. Virology (2006) 1.38
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West Nile virus genome cyclization and RNA replication require two pairs of long-distance RNA interactions. Virology (2008) 1.37
Dengue virus NS4B interacts with NS3 and dissociates it from single-stranded RNA. J Gen Virol (2006) 1.36
Structure and function of the 3' terminal six nucleotides of the west nile virus genome in viral replication. J Virol (2004) 1.33
The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis. J Cell Biol (2008) 1.32
2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase. PLoS Pathog (2012) 1.32
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Mass spectrometry-based profiling of phospholipids and sphingolipids in extracts from Saccharomyces cerevisiae. Yeast (2006) 1.30
Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation. PLoS Genet (2011) 1.30
Keratinocytes are cell targets of West Nile virus in vivo. J Virol (2011) 1.29
Genetic diversity and purifying selection in West Nile virus populations are maintained during host switching. Virology (2008) 1.29
Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles. Proc Natl Acad Sci U S A (2003) 1.28
Functional analysis of two cavities in flavivirus NS5 polymerase. J Biol Chem (2011) 1.28