Published in J Cell Sci on May 09, 2006
Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation. Mol Biol Cell (2008) 2.08
Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis. Proc Natl Acad Sci U S A (2011) 2.01
Thousands of rab GTPases for the cell biologist. PLoS Comput Biol (2011) 1.44
Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes. Mol Biol Cell (2009) 1.40
Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to target vesicles to the presynaptic density. Neurosci Lett (2008) 1.18
APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle. J Neurosci (2009) 1.13
Dynamics of dynamin during clathrin mediated endocytosis in PC12 cells. PLoS One (2008) 1.10
Differential dynamics of Rab3A and Rab27A on secretory granules. J Cell Sci (2007) 1.06
How peptide hormone vesicles are transported to the secretion site for exocytosis. Mol Endocrinol (2008) 1.04
Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic beta-cells. J Physiol (2008) 1.04
Small GTPase Rab17 regulates dendritic morphogenesis and postsynaptic development of hippocampal neurons. J Biol Chem (2012) 0.98
Multiplexing siRNAs to compress RNAi-based screen size in human cells. Nucleic Acids Res (2007) 0.98
Cholesterol controls lipid endocytosis through Rab11. Mol Biol Cell (2007) 0.96
Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. J Biol Chem (2010) 0.96
Cellular mechanisms of alpha herpesvirus egress: live cell fluorescence microscopy of pseudorabies virus exocytosis. PLoS Pathog (2014) 0.95
Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity. Mol Biol Cell (2012) 0.95
Rab27 and Rab3 sequentially regulate human sperm dense-core granule exocytosis. Proc Natl Acad Sci U S A (2012) 0.94
Distinct actions of Rab3 and Rab27 GTPases on late stages of exocytosis of insulin. Traffic (2014) 0.93
Distinct yet overlapping roles of Rab GTPases on synaptic vesicles. Small GTPases (2011) 0.93
Age-dependent preferential dense-core vesicle exocytosis in neuroendocrine cells revealed by newly developed monomeric fluorescent timer protein. Mol Biol Cell (2009) 0.93
A Rab11a-Rab8a-Myo5B network promotes stretch-regulated exocytosis in bladder umbrella cells. Mol Biol Cell (2013) 0.93
Total internal reflection fluorescence (TIRF) microscopy. Curr Protoc Cytom (2009) 0.92
HID-1, a new component of the peptidergic signaling pathway. Genetics (2010) 0.91
The Rab interacting lysosomal protein (RILP) homology domain functions as a novel effector domain for small GTPase Rab36: Rab36 regulates retrograde melanosome transport in melanocytes. J Biol Chem (2012) 0.91
PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport. Mol Endocrinol (2012) 0.90
The role of Rab3a in secretory vesicle docking requires association/dissociation of guanidine phosphates and Munc18-1. PLoS One (2007) 0.89
Carboxypeptidase E cytoplasmic tail mediates localization of synaptic vesicles to the pre-active zone in hypothalamic pre-synaptic terminals. J Neurochem (2010) 0.87
The GTPase Rab3b/3c-positive recycling vesicles are involved in cross-presentation in dendritic cells. Proc Natl Acad Sci U S A (2009) 0.87
Dennd3 functions as a guanine nucleotide exchange factor for small GTPase Rab12 in mouse embryonic fibroblasts. J Biol Chem (2014) 0.86
Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression. Mol Biol Cell (2012) 0.86
Regulation of podocalyxin trafficking by Rab small GTPases in 2D and 3D epithelial cell cultures. J Cell Biol (2016) 0.86
Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion. PLoS One (2015) 0.86
The GTPase Rab37 Participates in the Control of Insulin Exocytosis. PLoS One (2013) 0.85
Rab26 modulates the cell surface transport of α2-adrenergic receptors from the Golgi. J Biol Chem (2012) 0.85
Inhibition of endocytic vesicle fusion by Plk1-mediated phosphorylation of vimentin during mitosis. Cell Cycle (2013) 0.84
Phosphorylation of AATYK1 by Cdk5 suppresses its tyrosine phosphorylation. PLoS One (2010) 0.84
POLAR MAPPER: a computational tool for integrated visualization of protein interaction networks and mRNA expression data. J R Soc Interface (2008) 0.83
Roles of myosin Va and Rab3D in membrane remodeling of immature secretory granules. Cell Mol Neurobiol (2010) 0.80
Synaptotagmin 1 directs repetitive release by coupling vesicle exocytosis to the Rab3 cycle. Elife (2015) 0.79
An association study on genetic polymorphisms of Rab37 gene with the risk of esophageal squamous cell carcinoma in a Chinese Han population. Int J Med Sci (2013) 0.78
Interplay between Rab27a effectors in pancreatic β-cells. World J Diabetes (2015) 0.78
Rab3D is critical for secretory granule maturation in PC12 cells. PLoS One (2013) 0.78
EPI64 protein functions as a physiological GTPase-activating protein for Rab27 protein and regulates amylase release in rat parotid acinar cells. J Biol Chem (2011) 0.78
Role of Rab27 in synaptic transmission at the squid giant synapse. Proc Natl Acad Sci U S A (2008) 0.78
Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis. Elife (2015) 0.77
Rab3A, Rab27A, and Rab35 regulate different events during mouse oocyte meiotic maturation and activation. Histochem Cell Biol (2016) 0.77
A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair. J Cell Biol (2016) 0.77
Insulin regulates Rab3-Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes. Diabetologia (2015) 0.76
Imaging a target of Ca2+ signalling: dense core granule exocytosis viewed by total internal reflection fluorescence microscopy. Methods (2008) 0.76
Mutant Huntingtin Impairs BDNF Release from Astrocytes by Disrupting Conversion of Rab3a-GTP into Rab3a-GDP. J Neurosci (2016) 0.75
Proteomic analysis of three gonad types of swamp eel reveals genes differentially expressed during sex reversal. Sci Rep (2015) 0.75
The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells. Nat Commun (2016) 0.75
Molecular mechanism of docking of dense-core vesicles to the plasma membrane in neuroendocrine cells. Med Mol Morphol (2008) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell (2008) 6.66
Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol (2009) 5.44
AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain. Biochem J (2005) 2.76
Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane. Cell Metab (2007) 2.71
Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation. Mol Biol Cell (2008) 2.08
Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis. Neuron (2002) 2.01
The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. J Biol Chem (2001) 1.86
Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity. Genes Cells (2006) 1.76
Chronic olanzapine treatment causes differential expression of genes in frontal cortex of rats as revealed by DNA microarray technique. Neuropsychopharmacology (2006) 1.69
OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation. J Cell Biol (2011) 1.61
Regulation of synaptic transmission by RAB-3 and RAB-27 in Caenorhabditis elegans. Mol Biol Cell (2006) 1.61
Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells. J Biol Chem (2007) 1.56
Rab35 and its GAP EPI64C in T cells regulate receptor recycling and immunological synapse formation. J Biol Chem (2008) 1.54
Rab10 in insulin-stimulated GLUT4 translocation. Biochem J (2008) 1.53
Synaptotagmin IV regulates glial glutamate release. Proc Natl Acad Sci U S A (2004) 1.46
Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27. Dev Cell (2009) 1.45
Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets. J Biol Chem (2003) 1.45
Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes. Nat Cell Biol (2004) 1.45
Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin. J Cell Biol (2013) 1.44
Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells. Nat Cell Biol (2012) 1.42
Involvement of the Rab27 binding protein Slac2c/MyRIP in insulin exocytosis. Mol Biol Cell (2003) 1.41
An ARF6/Rab35 GTPase cascade for endocytic recycling and successful cytokinesis. Curr Biol (2012) 1.41
Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes. Mol Biol Cell (2009) 1.40
Rab35 regulates Arf6 activity through centaurin-β2 (ACAP2) during neurite outgrowth. J Cell Sci (2012) 1.39
Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse. Traffic (2008) 1.38
Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases. Structure (2008) 1.38
Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis. EMBO J (2010) 1.34
The actin-binding domain of Slac2-a/melanophilin is required for melanosome distribution in melanocytes. Mol Cell Biol (2003) 1.32
Comprehensive screening for novel rab-binding proteins by GST pull-down assay using 60 different mammalian Rabs. Traffic (2010) 1.30
The small GTPase Rab27B regulates amylase release from rat parotid acinar cells. J Cell Sci (2004) 1.30
Synaptotagmin interaction with the syntaxin/SNAP-25 dimer is mediated by an evolutionarily conserved motif and is sensitive to inositol hexakisphosphate. J Biol Chem (2004) 1.30
Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev Cell (2010) 1.25
Identification of EPI64 as a GTPase-activating protein specific for Rab27A. J Biol Chem (2006) 1.25
BCA2/Rabring7 promotes tetherin-dependent HIV-1 restriction. PLoS Pathog (2009) 1.24
The primate-specific protein TBC1D3 is required for optimal macropinocytosis in a novel ARF6-dependent pathway. Mol Biol Cell (2008) 1.23
The Slp4-a linker domain controls exocytosis through interaction with Munc18-1.syntaxin-1a complex. Mol Biol Cell (2006) 1.22
Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4. EMBO Rep (2013) 1.19
The C2B domain of rabphilin directly interacts with SNAP-25 and regulates the docking step of dense core vesicle exocytosis in PC12 cells. J Biol Chem (2005) 1.17
The secretory granule-associated protein CAPS2 regulates neurotrophin release and cell survival. J Neurosci (2004) 1.12
Dysferlin deficiency shows compensatory induction of Rab27A/Slp2a that may contribute to inflammatory onset. Am J Pathol (2008) 1.12
Small GTPase Rab12 regulates constitutive degradation of transferrin receptor. Traffic (2011) 1.12
Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis. FASEB J (2007) 1.12
The Leishmania donovani lipophosphoglycan excludes the vesicular proton-ATPase from phagosomes by impairing the recruitment of synaptotagmin V. PLoS Pathog (2009) 1.11
Exome sequencing reveals a homozygous SYT14 mutation in adult-onset, autosomal-recessive spinocerebellar ataxia with psychomotor retardation. Am J Hum Genet (2011) 1.10
Synaptotagmin V and IX isoforms control Ca2+ -dependent insulin exocytosis. J Cell Sci (2004) 1.08
Rab35 regulates phagosome formation through recruitment of ACAP2 in macrophages during FcγR-mediated phagocytosis. J Cell Sci (2011) 1.07
NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by switching binding specificity from phosphatidylserine to Sec15. EMBO J (2013) 1.06
Melanoregulin regulates retrograde melanosome transport through interaction with the RILP-p150Glued complex in melanocytes. J Cell Sci (2012) 1.05
Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity. Genes Cells (2008) 1.04
Constitutive GDP/GTP exchange and secretion-dependent GTP hydrolysis activity for Rab27 in platelets. J Biol Chem (2006) 1.04
Synaptotagmin-like protein 5: a novel Rab27A effector with C-terminal tandem C2 domains. Biochem Biophys Res Commun (2002) 1.03
Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes. J Biol Chem (2010) 1.02
Spatial segregation of degradation- and recycling-trafficking pathways in COS-1 cells. Biochem Biophys Res Commun (2007) 1.02
The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking. Traffic (2011) 1.01
Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12–5-16L2 complex. Autophagy (2011) 1.01
Analysis of the role of Rab27 effector Slp4-a/Granuphilin-a in dense-core vesicle exocytosis. Methods Enzymol (2005) 1.01
Plasmalemmal sealing of transected mammalian neurites is a gradual process mediated by Ca(2+)-regulated proteins. J Neurosci Res (2003) 1.00
Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology. J Cell Sci (2012) 1.00
Characterization of the molecular defects in Rab27a, caused by RAB27A missense mutations found in patients with Griscelli syndrome. J Biol Chem (2003) 1.00
Synaptotagmin V is targeted to dense-core vesicles that undergo calcium-dependent exocytosis in PC12 cells. J Biol Chem (2002) 0.99
Identification and biochemical analysis of Slac2-c/MyRIP as a Rab27A-, myosin Va/VIIa-, and actin-binding protein. Methods Enzymol (2005) 0.99
Role of Rab family GTPases and their effectors in melanosomal logistics. J Biochem (2012) 0.99
Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth. J Cell Sci (2013) 0.98
Small GTPase Rab17 regulates dendritic morphogenesis and postsynaptic development of hippocampal neurons. J Biol Chem (2012) 0.98
Cholesterol controls lipid endocytosis through Rab11. Mol Biol Cell (2007) 0.96
Vesicular reuptake inhibition by a synaptotagmin I C2B domain antibody at the squid giant synapse. Proc Natl Acad Sci U S A (2004) 0.96
Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells. Genes Cells (2006) 0.95
Synaptotagmin I binds intestinal epithelial NHE3 and mediates cAMP- and Ca2+-induced endocytosis by recruitment of AP2 and clathrin. Am J Physiol Gastrointest Liver Physiol (2007) 0.95
Non-polarized distribution of synaptotagmin IV in neurons: evidence that synaptotagmin IV is not a synaptic vesicle protein. Neurosci Res (2002) 0.95
Synaptotagmin VII modulates the kinetics of dense-core vesicle exocytosis in PC12 cells. Genes Cells (2007) 0.95
LMTK1/AATYK1 is a novel regulator of axonal outgrowth that acts via Rab11 in a Cdk5-dependent manner. J Neurosci (2012) 0.95
Functional analysis of slac2-a/melanophilin as a linker protein between Rab27A and myosin Va in melanosome transport. Methods Enzymol (2005) 0.95
Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity. Mol Biol Cell (2012) 0.95
Rab38 targets to lamellar bodies and normalizes their sizes in lung alveolar type II epithelial cells. Am J Physiol Lung Cell Mol Physiol (2011) 0.94
Adenovirus-mediated silencing of synaptotagmin 9 inhibits Ca2+-dependent insulin secretion in islets. FEBS Lett (2005) 0.94
Functional involvement of Rab1A in microtubule-dependent anterograde melanosome transport in melanocytes. J Cell Sci (2012) 0.93
Age-dependent preferential dense-core vesicle exocytosis in neuroendocrine cells revealed by newly developed monomeric fluorescent timer protein. Mol Biol Cell (2009) 0.93
A complete Rab screening reveals novel insights in Weibel-Palade body exocytosis. J Cell Sci (2012) 0.93
Molecular mechanism of myosin Va recruitment to dense core secretory granules. Traffic (2011) 0.92
Functional analysis of Slac2-c/MyRIP as a linker protein between melanosomes and myosin VIIa. J Biol Chem (2005) 0.92
Expression of Rab27B-binding protein Slp1 in pancreatic acinar cells and its involvement in amylase secretion. Arch Biochem Biophys (2008) 0.92
Human RME-8 is involved in membrane trafficking through early endosomes. Cell Struct Funct (2008) 0.92
The exocytosis regulator synaptotagmin V controls phagocytosis in macrophages. J Immunol (2008) 0.92
Decoding the regulation of mast cell exocytosis by networks of Rab GTPases. J Immunol (2012) 0.91
The Rab interacting lysosomal protein (RILP) homology domain functions as a novel effector domain for small GTPase Rab36: Rab36 regulates retrograde melanosome transport in melanocytes. J Biol Chem (2012) 0.91
Rab27a regulates exocytosis of tertiary and specific granules in human neutrophils. J Immunol (2008) 0.91
Rab proteins regulate epithelial sodium channel activity in colonic epithelial HT-29 cells. Biochem Biophys Res Commun (2005) 0.90
Dvl regulates endo- and exocytotic processes through binding to synaptotagmin. Genes Cells (2007) 0.90
Versatile roles of R-Ras GAP in neurite formation of PC12 cells and embryonic vascular development. J Biol Chem (2006) 0.90
Syntaxin-3 is required for melanosomal localization of Tyrp1 in melanocytes. J Invest Dermatol (2013) 0.89
Role of the polybasic sequence in the Doc2alpha C2B domain in dense-core vesicle exocytosis in PC12 cells. J Neurochem (2010) 0.89
Arf6, Rab11 and transferrin receptor define distinct populations of recycling endosomes. Commun Integr Biol (2013) 0.89
Synaptotagmin XI regulates phagocytosis and cytokine secretion in macrophages. J Immunol (2013) 0.88
The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes. Mol Biol Cell (2011) 0.88
A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5). J Biol Chem (2009) 0.87
The polybasic sequence in the C2B domain of rabphilin is required for the vesicle docking step in PC12 cells. J Neurochem (2006) 0.86
Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression. Mol Biol Cell (2012) 0.86