PubRank

David Eisenberg

Author PubWeight™ 328.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The Database of Interacting Proteins: 2004 update. Nucleic Acids Res 2004 23.67
2 Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006 18.74
3 The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data. Nat Biotechnol 2004 16.08
4 DIP, the Database of Interacting Proteins: a research tool for studying cellular networks of protein interactions. Nucleic Acids Res 2002 15.70
5 The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. PLoS Biol 2007 13.99
6 Structure of the cross-beta spine of amyloid-like fibrils. Nature 2005 11.56
7 Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature 2007 10.02
8 The minimum information required for reporting a molecular interaction experiment (MIMIx). Nat Biotechnol 2007 8.24
9 Protein interactions: two methods for assessment of the reliability of high throughput observations. Mol Cell Proteomics 2002 8.11
10 Broadening the horizon--level 2.5 of the HUPO-PSI format for molecular interactions. BMC Biol 2007 8.03
11 Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc Natl Acad Sci U S A 2006 7.29
12 Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels. Cell 2012 6.83
13 The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue. Proc Natl Acad Sci U S A 2003 5.83
14 PSICQUIC and PSISCORE: accessing and scoring molecular interactions. Nat Methods 2011 5.01
15 3D domain swapping: as domains continue to swap. Protein Sci 2002 4.35
16 Prolinks: a database of protein functional linkages derived from coevolution. Genome Biol 2004 4.07
17 Functional amyloids as natural storage of peptide hormones in pituitary secretory granules. Science 2009 3.78
18 Identifying the amylome, proteins capable of forming amyloid-like fibrils. Proc Natl Acad Sci U S A 2010 3.50
19 The origin of protein interactions and allostery in colocalization. Nature 2007 3.34
20 Atomic view of a toxic amyloid small oligomer. Science 2012 3.13
21 Continuation and satisfaction of reversible contraception. Obstet Gynecol 2011 3.03
22 Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure. Nature 2005 2.99
23 Inference of protein function from protein structure. Structure 2005 2.90
24 The 3D profile method for identifying fibril-forming segments of proteins. Proc Natl Acad Sci U S A 2006 2.88
25 Computational methods of analysis of protein-protein interactions. Curr Opin Struct Biol 2003 2.80
26 Describing biological protein interactions in terms of protein states and state transitions: the LiveDIP database. Mol Cell Proteomics 2002 2.76
27 Toward rational protein crystallization: A Web server for the design of crystallizable protein variants. Protein Sci 2007 2.57
28 Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation. Nature 2011 2.46
29 Unique transcriptome signature of Mycobacterium tuberculosis in pulmonary tuberculosis. Infect Immun 2006 2.27
30 Sharing publication-related data and materials: responsibilities of authorship in the life sciences. Plant Physiol 2003 2.25
31 Recent atomic models of amyloid fibril structure. Curr Opin Struct Biol 2006 2.05
32 Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol 2003 2.04
33 Ethical considerations of complementary and alternative medical therapies in conventional medical settings. Ann Intern Med 2002 2.02
34 Inferring protein domain interactions from databases of interacting proteins. Genome Biol 2005 1.97
35 A specific secretion system mediates PPE41 transport in pathogenic mycobacteria. Mol Microbiol 2006 1.97
36 Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci 2010 1.95
37 Molecular mechanisms for protein-encoded inheritance. Nat Struct Mol Biol 2009 1.94
38 Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin). Protein Sci 2008 1.89
39 Deposition diseases and 3D domain swapping. Structure 2006 1.88
40 Use of logic relationships to decipher protein network organization. Science 2004 1.86
41 An amyloid-forming segment of beta2-microglobulin suggests a molecular model for the fibril. Proc Natl Acad Sci U S A 2004 1.85
42 GXXXG and AXXXA: common alpha-helical interaction motifs in proteins, particularly in extremophiles. Biochemistry 2002 1.82
43 Genomic evidence that the intracellular proteins of archaeal microbes contain disulfide bonds. Proc Natl Acad Sci U S A 2002 1.81
44 Molecular basis for amyloid-beta polymorphism. Proc Natl Acad Sci U S A 2011 1.76
45 In silico simulation of biological network dynamics. Nat Biotechnol 2004 1.74
46 GXXXG and GXXXA motifs stabilize FAD and NAD(P)-binding Rossmann folds through C(alpha)-H... O hydrogen bonds and van der waals interactions. J Mol Biol 2002 1.74
47 Use of genetic profiling in leprosy to discriminate clinical forms of the disease. Science 2003 1.73
48 Bacterial inclusion bodies contain amyloid-like structure. PLoS Biol 2008 1.63
49 Cross-beta order and diversity in nanocrystals of an amyloid-forming peptide. J Mol Biol 2003 1.59
50 Towards a pharmacophore for amyloid. PLoS Biol 2011 1.58
51 Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy. J Clin Invest 2008 1.54
52 Toxic fibrillar oligomers of amyloid-β have cross-β structure. Proc Natl Acad Sci U S A 2012 1.53
53 Structure and proposed activity of a member of the VapBC family of toxin-antitoxin systems. VapBC-5 from Mycobacterium tuberculosis. J Biol Chem 2008 1.49
54 Structural models of amyloid-like fibrils. Adv Protein Chem 2006 1.49
55 A systematic screen of beta(2)-microglobulin and insulin for amyloid-like segments. Proc Natl Acad Sci U S A 2006 1.49
56 The MiSink Plugin: Cytoscape as a graphical interface to the Database of Interacting Proteins. Bioinformatics 2007 1.49
57 A double S shape provides the structural basis for the extraordinary binding specificity of Dscam isoforms. Cell 2008 1.48
58 Molecular basis for insulin fibril assembly. Proc Natl Acad Sci U S A 2009 1.47
59 Seeded conversion of recombinant prion protein to a disulfide-bonded oligomer by a reduction-oxidation process. Nat Struct Biol 2003 1.46
60 Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process. Protein Sci 2009 1.46
61 Recurated protein interaction datasets. Nat Methods 2009 1.43
62 Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates. Proc Natl Acad Sci U S A 2012 1.39
63 Cooperative hydrogen bonding in amyloid formation. Protein Sci 2007 1.33
64 Short protein segments can drive a non-fibrillizing protein into the amyloid state. Protein Eng Des Sel 2009 1.31
65 Visualization and interpretation of protein networks in Mycobacterium tuberculosis based on hierarchical clustering of genome-wide functional linkage maps. Nucleic Acids Res 2003 1.31
66 Granulysin crystal structure and a structure-derived lytic mechanism. J Mol Biol 2003 1.30
67 The TB structural genomics consortium: providing a structural foundation for drug discovery. Curr Drug Targets Infect Disord 2002 1.28
68 Characteristics of amyloid-related oligomers revealed by crystal structures of macrocyclic β-sheet mimics. J Am Chem Soc 2011 1.27
69 Multicopy crystallographic refinement of a relaxed glutamine synthetase from Mycobacterium tuberculosis highlights flexible loops in the enzymatic mechanism and its regulation. Biochemistry 2002 1.27
70 Structures of the two 3D domain-swapped RNase A trimers. Protein Sci 2002 1.24
71 β₂-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages. Nat Struct Mol Biol 2010 1.22
72 Gram-positive DsbE proteins function differently from Gram-negative DsbE homologs. A structure to function analysis of DsbE from Mycobacterium tuberculosis. J Biol Chem 2003 1.22
73 Two amyloid States of the prion protein display significantly different folding patterns. J Mol Biol 2010 1.16
74 Runaway domain swapping in amyloid-like fibrils of T7 endonuclease I. Proc Natl Acad Sci U S A 2006 1.16
75 Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity. Nat Chem 2012 1.16
76 Using inferred residue contacts to distinguish between correct and incorrect protein models. Bioinformatics 2008 1.15
77 A novel inhibitor of Mycobacterium tuberculosis pantothenate synthetase. J Biomol Screen 2006 1.14
78 Crystal structure of a RuBisCO-like protein from the green sulfur bacterium Chlorobium tepidum. Structure 2005 1.14
79 Thiol-disulfide exchange in an immunoglobulin-like fold: structure of the N-terminal domain of DsbD. Biochemistry 2002 1.13
80 Sociodemographic determinants of the utilization of specific types of complementary and alternative medicine: an analysis based on a nationally representative survey sample. J Altern Complement Med 2005 1.13
81 Management of steal syndrome resulting from dialysis access. Semin Vasc Surg 2004 1.12
82 Utilizing logical relationships in genomic data to decipher cellular processes. FEBS J 2005 1.11
83 A web-based comparative genomics tutorial for investigating microbial genomes. Microbiol Educ 2004 1.11
84 Macrocyclic β-sheet peptides that inhibit the aggregation of a tau-protein-derived hexapeptide. J Am Chem Soc 2011 1.10
85 A hierarchic approach to the design of hexameric helical barrels. J Mol Biol 2002 1.10
86 Selective dimerization of a C2H2 zinc finger subfamily. Mol Cell 2003 1.09
87 The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs). Protein Sci 2003 1.05
88 Mycobacterium tuberculosis gene expression profiling within the context of protein networks. Microbes Infect 2006 1.05
89 The evolving role of 3D domain swapping in proteins. Structure 2004 1.05
90 Draft crystal structure of the vault shell at 9-A resolution. PLoS Biol 2007 1.05
91 The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg²⁺ ion in the active site and a putative RNA-binding site. Protein Sci 2012 1.05
92 Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate. Protein Sci 2003 1.04
93 Crystal structure of the pantothenate synthetase from Mycobacterium tuberculosis, snapshots of the enzyme in action. Biochemistry 2006 1.03
94 The directional atomic solvation energy: an atom-based potential for the assignment of protein sequences to known folds. Proc Natl Acad Sci U S A 2002 1.02
95 Identifying cognate binding pairs among a large set of paralogs: the case of PE/PPE proteins of Mycobacterium tuberculosis. PLoS Comput Biol 2008 1.02
96 Crystallographic studies of prion protein (PrP) segments suggest how structural changes encoded by polymorphism at residue 129 modulate susceptibility to human prion disease. J Biol Chem 2010 1.01
97 Detection of parallel functional modules by comparative analysis of genome sequences. Nat Biotechnol 2005 1.00
98 Structure and assembly of an augmented Sm-like archaeal protein 14-mer. Proc Natl Acad Sci U S A 2003 1.00
99 Structure and function of an archaeal homolog of survival protein E (SurEalpha): an acid phosphatase with purine nucleotide specificity. J Mol Biol 2003 0.99
100 Structure of superoxide dismutase from Pyrobaculum aerophilum presents a challenging case in molecular replacement with multiple molecules, pseudo-symmetry and twinning. Acta Crystallogr D Biol Crystallogr 2003 0.99
101 The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function. J Mol Biol 2006 0.98
102 Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme. J Mol Biol 2005 0.96
103 Role of the C-terminal 28 residues of beta2-microglobulin in amyloid fibril formation. Biochemistry 2003 0.95
104 Structural genomics of Mycobacterium tuberculosis: a preliminary report of progress at UCLA. Biophys Chem 2003 0.95
105 The crystal structure of the Mycobacterium tuberculosis Rv3019c-Rv3020c ESX complex reveals a domain-swapped heterotetramer. Protein Sci 2010 0.94
106 Atomic structures suggest determinants of transmission barriers in mammalian prion disease. Biochemistry 2011 0.93
107 Multidimensional structure-activity relationship of a protein in its aggregated states. Angew Chem Int Ed Engl 2010 0.93
108 The evolution of complementary and alternative medicine (CAM) in the USA over the last 20 years. Forsch Komplementmed 2013 0.92
109 A proposed mechanism for the promotion of prion conversion involving a strictly conserved tyrosine residue in the β2-α2 loop of PrPC. J Biol Chem 2014 0.91
110 Structure of a Nudix protein from Pyrobaculum aerophilum reveals a dimer with two intersubunit beta-sheets. Acta Crystallogr D Biol Crystallogr 2002 0.90
111 The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase. Acta Crystallogr D Biol Crystallogr 2005 0.90
112 Reflections on the past and future of integrative medicine from a lifelong student of the integration of Chinese and Western medicine. Chin J Integr Med 2011 0.89
113 A synthetic biochemistry system for the in vitro production of isoprene from glycolysis intermediates. Protein Sci 2014 0.89
114 Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-A resolution. Protein Sci 2002 0.87
115 Structures of segments of α-synuclein fused to maltose-binding protein suggest intermediate states during amyloid formation. Protein Sci 2011 0.86
116 Debating the Worth of NCCAM Research. Science 2006 0.85
117 Increased membrane type 1 matrix metalloproteinase expression from adenoma to colon cancer: a possible mechanism of neoplastic progression. Dis Colon Rectum 2002 0.85
118 X-ray crystallographic structure of an artificial beta-sheet dimer. J Am Chem Soc 2010 0.85
119 Detecting coordinated regulation of multi-protein complexes using logic analysis of gene expression. BMC Syst Biol 2009 0.84
120 The structure of a fibril-forming sequence, NNQQNY, in the context of a globular fold. Protein Sci 2008 0.83
121 Human prion protein sequence elements impede cross-species chronic wasting disease transmission. J Clin Invest 2015 0.83
122 Inferring molecular function: contributions from functional linkages. Trends Genet 2008 0.82
123 Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. PLoS One 2013 0.82
124 Heterogeneity of molecular targets on clonal cancer lines derived from a novel hormone-refractory prostate cancer tumor system. Prostate 2003 0.82
125 The protein network as a tool for finding novel drug targets. Prog Drug Res 2007 0.80
126 The mechanism of the amyloidogenic conversion of T7 endonuclease I. J Biol Chem 2007 0.80
127 Ribonuclease A suggests how proteins self-chaperone against amyloid fiber formation. Protein Sci 2011 0.80
128 Human prion protein sequence elements impede cross-species chronic wasting disease transmission. J Clin Invest 2015 0.79
129 Splenic rupture as a complication of colonoscopy: report of a case. Surg Today 2009 0.79
130 DPANN: improved sequence to structure alignments following fold recognition. Proteins 2004 0.78
131 How effective is health coaching in reducing health services expenditures? Med Care 2015 0.78
132 Ball-and-socket stacking of supercharged geodesic polyarenes: bonding by interstitial lithium ions. J Am Chem Soc 2005 0.77
133 A pilot study of Qigong for reducing cocaine craving early in recovery. J Altern Complement Med 2012 0.77
134 Salvage or recovery of failed targets by mutagenesis to reduce surface entropy. Methods Mol Biol 2014 0.77
135 PFIT and PFRIT: bioinformatic algorithms for detecting glycosidase function from structure and sequence. Protein Sci 2004 0.75
136 Functional linkages can reveal protein complexes for structure determination. Structure 2007 0.75
137 Ultrafast Time-Resolved Studies on Fluorescein for Recognition Strands Architecture in Amyloid Fibrils. J Phys Chem B 2017 0.75
138 Pondering the placebo effect. Newsweek 2002 0.75
139 Nutritional deficiency in healthcare education. Explore (NY) 2013 0.75
140 Cancer. Easing the treatment. Newsweek 2002 0.75
141 Pediatric guidelines. Explore (NY) 2006 0.75
142 What Competencies Should Medical Students Attain in Nutritional Medicine? Explore (NY) 2015 0.75
143 Research. Finding out what works. Newsweek 2002 0.75
144 Integrative medicine in 2021: an imagined retrospective. Explore (NY) 2012 0.75
145 Cardiac disease. Ways to heal your heart. Newsweek 2002 0.75
146 Back pain. Beyond the backache. Newsweek 2002 0.75