Published in J Biol Chem on July 25, 1975
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Ketohexokinase, isoenzymes of glucokinase and glycogen synthesis from hexoses in neonatal rat liver. Biochem J (1964) 2.55
cAMP stimulates transcription of the gene for cytosolic phosphoenolpyruvate carboxykinase in rat liver nuclei. Proc Natl Acad Sci U S A (1982) 2.45
Identification of a cAMP regulatory region in the gene for rat cytosolic phosphoenolpyruvate carboxykinase (GTP). Use of chimeric genes transfected into hepatoma cells. J Biol Chem (1984) 2.27
Changes in lipid synthesis in rat liver during development. Biochem J (1967) 2.17
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Isolation and characterization of the gene coding for cytosolic phosphoenolpyruvate carboxykinase (GTP) from the rat. Proc Natl Acad Sci U S A (1983) 1.99
Gene transfer in vivo: sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake. Proc Natl Acad Sci U S A (1994) 1.98
Tissue-specific expression and dietary regulation of a chimeric phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic mice. J Biol Chem (1988) 1.91
Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt. Biochem J (2000) 1.87
Mechanism of 3-mercaptopicolinic acid inhibition of hepatic phosphoenolpyruvate carboxykinase (GTP). J Biol Chem (1976) 1.74
Phosphoenolpyruvate carboxykinase and the synthesis of glyceride-glycerol from pyruvate in adipose tissue. J Biol Chem (1967) 1.69
Inhibition of protein degradation in isolated rat hepatocytes. Biochem J (1977) 1.68
The role of the CCAAT/enhancer-binding protein in the transcriptional regulation of the gene for phosphoenolpyruvate carboxykinase (GTP). Mol Cell Biol (1990) 1.67
Production and utilization of acetate in mammals. Biochem J (1974) 1.61
Synthesis and degradation of phosphoenolpyruvate carboxylase in rat liver and adipose tissue. Changes during a starvation-re-feeding cycle. Biochem J (1973) 1.55
Relative roles of CCAAT/enhancer-binding protein beta and cAMP regulatory element-binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase (GTP). J Biol Chem (1993) 1.54
Tissue-specific expression of glucokinase: identification of the gene product in liver and pancreatic islets. Proc Natl Acad Sci U S A (1986) 1.53
Molecular cloning of glucokinase cDNA. Developmental and dietary regulation of glucokinase mRNA in rat liver. J Biol Chem (1987) 1.53
Sterol regulatory element-binding protein-1c mimics the negative effect of insulin on phosphoenolpyruvate carboxykinase (GTP) gene transcription. J Biol Chem (2001) 1.53
Rapid changes in the concentration of phosphoenolpyruvate carboxykinase mRNA in rat liver and kidney. Effects of insulin and cyclic AMP. J Biol Chem (1982) 1.52
C/EBP alpha: a critical regulator of genes governing integrative metabolic processes. Curr Opin Genet Dev (1995) 1.51
The citrate cleavage pathway and lipogenesis in rat adipose tissue: replenishment of oxaloacetate. J Lipid Res (1967) 1.51
Cyclic AMP induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription is mediated by multiple promoter elements. J Biol Chem (1991) 1.49
A possible physiological role for glyceroneogenesis in rat adipose tissue. J Biol Chem (1970) 1.49
Citrate, pyruvate, and lactate contaminants of commercial serum albumin. J Lipid Res (1968) 1.49
The initial synthesis of proteins during development. Phosphoenolpyruvate carboxylase in rat liver at birth. Biochem J (1972) 1.47
Supply and utilization of acetate in mammals. Am J Clin Nutr (1972) 1.46
Glyceride-glycerol synthesis from pyruvate. Adaptive changes in phosphoenolpyruvate carboxykinase and pyruvate carboxylase in adipose tissue and liver. J Biol Chem (1969) 1.44
Phosphoenolpyruvate carboxykinase. I. Its role in gluconeogenesis. Am J Clin Nutr (1972) 1.43
The relative significance of acetate and glucose as precursors for lipid synthesis in liver and adipose tissue from ruminants. Biochem J (1967) 1.40
Identification of multiple protein binding domains in the promoter-regulatory region of the phosphoenolpyruvate carboxykinase (GTP) gene. J Biol Chem (1989) 1.40
Effects of weak bases on the degradation of endogenous and exogenous proteins by rat yolk sacs. Biochem J (1980) 1.40
The development of gluconeogenesis in rat liver: experiments in vivo. Biochem J (1969) 1.39
Metabolic effects of developmental, tissue-, and cell-specific expression of a chimeric phosphoenolpyruvate carboxykinase (GTP)/bovine growth hormone gene in transgenic mice. J Biol Chem (1990) 1.39
Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. I. Multiple hormone regulatory elements and the effects of enhancers. J Biol Chem (1986) 1.32
Increase in level of functional messenger RNA coding for phosphoenolpyruvate carboxykinase (GTP) during induction by cyclic adenosine 3':5'-monophosphate. J Biol Chem (1977) 1.32
Binding properties and biological potencies of insulin-like growth factors in L6 myoblasts. Biochem J (1986) 1.32
Insulin-like growth factors 1 and 2 in bovine colostrum. Sequences and biological activities compared with those of a potent truncated form. Biochem J (1988) 1.30
Rapid loss of translatable messenger RNA of phosphoenolpyruvate carboxykinase during glucose repression in liver. Proc Natl Acad Sci U S A (1974) 1.29
Reduced rates of proteolysis in transformed cells. Nature (1977) 1.26
Cyclic AMP stabilizes the mRNA for phosphoenolpyruvate carboxykinase (GTP) against degradation. J Biol Chem (1988) 1.26
Gluconeogenesis and lipogenesis in tissue from ruminant and nonruminant animals. Fed Proc (1969) 1.25
An analysis of regulatory elements in the phosphoenolpyruvate carboxykinase (GTP) gene which are responsible for its tissue-specific expression and metabolic control in transgenic mice. J Biol Chem (1994) 1.24
Modulation of glucose responsiveness of insulinoma beta-cells by graded overexpression of glucokinase. Proc Natl Acad Sci U S A (1997) 1.24
The development of gluconeogenesis in rat liver. Effects of glucagon and ether. Biochem J (1970) 1.23
Increased degradation rates of protein synthesized in hepatoma cells in the presence of amino acid analogues. Biochem J (1975) 1.23
Insulin inhibition of protein degradation in cell monolayers. J Cell Physiol (1980) 1.23
Identification of a DNA clone to phosphoenolpyruvate carboxykinase (GTP) from rat cytosol. Alterations in phosphoenolpyruvate carboxykinase RNA levels detectable by hybridization. J Biol Chem (1981) 1.23
Inactivation of the murine pyruvate dehydrogenase (Pdha1) gene and its effect on early embryonic development. Mol Genet Metab (2001) 1.22
Hypoglycemia and impaired hepatic glucose production in mice with a deletion of the C/EBPbeta gene. J Clin Invest (1999) 1.22
Degradation of phosphoenolpyruvate carboxykinase (guanosine triphosphate) in vivo and in vitro. Biochem J (1974) 1.21
Effects of cyclic adenosine monophosphate, dexamethasone and insulin on phosphoenolpyruvate carboxykinase synthesis in Reuber H-35 hepatoma cells. Biochemistry (1975) 1.20
Nucleotide sequence of the mRNA encoding the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) from the chicken. Proc Natl Acad Sci U S A (1986) 1.20
The pyruvate kinase gene as a model for studies of glucose-dependent regulation of gene expression in the endocrine pancreatic beta-cell type. J Biol Chem (1993) 1.20
Phosphopyruvate carboxylase induction by L-tryptophan. Effects on synthesis and degradation of the enzyme. Biochem J (1973) 1.19
The development of gluconeogenesis in rat liver. Controlling factors in the newborn. Biochem J (1971) 1.19
The effect of concentration on glucose phosphorylation and incorporation into glycogen in the livers of foetal and adult rats and sheep. Biochem J (1964) 1.19
Protein degradation in hepatocyte monolayers. Effects of glucagon, adenosine 3':5'-cyclic monophosphate and insulin. Biochem J (1980) 1.18
The regulation of gluconeogenesis in mammalian liver. The role of mitochondrial phosphoenolpyruvate carboxykinase. J Biol Chem (1973) 1.17
Purification and properties of rat liver fructokinase. J Biol Chem (1967) 1.17
Construction and cloning of rat albumin structural gene sequences. Proc Natl Acad Sci U S A (1979) 1.17
Trans regulation of the phosphoenolpyruvate carboxykinase (GTP) gene, identified by deletions in chromosome 7 of the mouse. Proc Natl Acad Sci U S A (1986) 1.16
Thyroid hormone regulates transcription of the gene for cytosolic phosphoenolpyruvate carboxykinase (GTP) in rat liver. Biochemistry (1985) 1.16
The interrelationships of the various pathways forming gluconeogenic precursors in guinea pig liver mitochondria. J Biol Chem (1971) 1.16
Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta have an attenuated response to cAMP and impaired carbohydrate metabolism. J Biol Chem (2001) 1.15
Glyceroneogenesis and the source of glycerol for hepatic triacylglycerol synthesis in humans. J Biol Chem (2001) 1.15
Regulation of gluconeogenesis during exposure of young rats to hypoxic conditions. Biochem J (1971) 1.13
Biological properties of poly-L-lysine-DNA complexes generated by cooperative binding of the polycation. J Biol Chem (2001) 1.12
Glucocorticoids regulate the induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription during diabetes. J Biol Chem (1993) 1.11
Regulation of the breakdown rates of biotin-containing proteins in Swiss 3T3-L1 cells. Biochem J (1988) 1.10
Novel recombinant fusion protein analogues of insulin-like growth factor (IGF)-I indicate the relative importance of IGF-binding protein and receptor binding for enhanced biological potency. J Mol Endocrinol (1992) 1.10
The relative stability of liver cytosol enzymes incubated in vitro. Biochem J (1974) 1.09
Purification and partial sequence analysis of insulin-like growth factor-1 from bovine colostrum. Biochem J (1986) 1.09
Gene transfer into the airway epithelium of animals by targeting the polymeric immunoglobulin receptor. J Clin Invest (1995) 1.08
Structure and acute-phase regulation of the rat alpha 2-macroglobulin gene. Biochemistry (1988) 1.07
C/EBP and the control of phosphoenolpyruvate carboxykinase gene transcription in the liver. J Biol Chem (1998) 1.06
Adaptive changes in enzyme activity and metabolic pathways in adipose tissue from meal-fed rats. J Lipid Res (1966) 1.06
Hexokinase isoenzymes of RIN-m5F insulinoma cells. Expression of glucokinase gene in insulin-producing cells. Biochem J (1987) 1.06