Published in Oncogene on May 15, 2006
Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics. Breast Cancer Res (2010) 1.94
The genomic landscape of retinoblastoma: a review. Clin Experiment Ophthalmol (2013) 1.81
Differential patterns of allelic loss in estrogen receptor-positive infiltrating lobular and ductal breast cancer. Genes Chromosomes Cancer (2008) 1.10
Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics. Breast Cancer Res (2015) 1.08
The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas. Oncogene (2011) 1.00
Immunophenotypic and genomic characterization of papillary carcinomas of the breast. J Pathol (2011) 0.95
Identification of metastasis-associated breast cancer genes using a high-resolution whole genome profiling approach. J Cancer Res Clin Oncol (2010) 0.93
Integrative analysis of a cancer somatic mutome. Mol Cancer (2007) 0.92
Genomics and premalignant breast lesions: clues to the development and progression of lobular breast cancer. Breast Cancer Res (2007) 0.86
Atbf1 regulates pubertal mammary gland development likely by inhibiting the pro-proliferative function of estrogen-ER signaling. PLoS One (2012) 0.86
An array CGH based genomic instability index (G2I) is predictive of clinical outcome in breast cancer and reveals a subset of tumors without lymph node involvement but with poor prognosis. BMC Med Genomics (2012) 0.83
Merotelic attachments and non-homologous end joining are the basis of chromosomal instability. Cell Div (2010) 0.81
Microsatellite stable colorectal cancers stratified by the BRAF V600E mutation show distinct patterns of chromosomal instability. PLoS One (2014) 0.80
Quantitative multigene FISH on breast carcinomas identifies der(1;16)(q10;p10) as an early event in luminal A tumors. Genes Chromosomes Cancer (2014) 0.77
Dual-color fluorescence in situ hybridization reveals an association of chromosome 8q22 but not 8p21 imbalance with high grade invasive breast carcinoma. PLoS One (2013) 0.77
Zinc Finger Homeodomain Factor Zfhx3 Is Essential for Mammary Lactogenic Differentiation by Maintaining Prolactin Signaling Activity. J Biol Chem (2016) 0.77
Genomic heterogeneity of breast tumor pathogenesis. Clin Med Oncol (2009) 0.76
Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology (1991) 30.87
Segmental duplications and copy-number variation in the human genome. Am J Hum Genet (2005) 13.33
DNA microarrays for comparative genomic hybridization based on DOP-PCR amplification of BAC and PAC clones. Genes Chromosomes Cancer (2003) 4.68
E-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers. EMBO J (1995) 4.55
Fully automatic quantification of microarray image data. Genome Res (2002) 3.47
E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain. Oncogene (1996) 3.35
Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas. Cancer Res (2004) 2.56
Haploinsufficiency for tumour suppressor genes: when you don't need to go all the way. Biochim Biophys Acta (2004) 2.04
Comparative genomic hybridization of breast tumors stratified by histological grade reveals new insights into the biological progression of breast cancer. Cancer Res (1999) 2.02
Ever since Knudson. Trends Genet (2001) 1.96
Different genetic pathways in the evolution of invasive breast cancer are associated with distinct morphological subtypes. J Pathol (1999) 1.76
Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast. Int J Cancer (2001) 1.64
Haplo-insufficiency? Let me count the ways. Genes Dev (2001) 1.59
Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma. Cancer (2004) 1.40
Genetic alterations in lobular breast cancer by comparative genomic hybridization. Int J Cancer (1997) 1.34
Allele loss on chromosome 16q24.2-qter occurs frequently in breast cancers irrespectively of differences in phenotype and extent of spread. Cancer Res (1994) 1.27
Loss of heterozygosity mapping at chromosome arm 16q in 712 breast tumors reveals factors that influence delineation of candidate regions. Cancer Res (2001) 1.23
E-cadherin and loss of heterozygosity at chromosome 16 in breast carcinogenesis: different genetic pathways in ductal and lobular breast cancer? Breast Cancer Res (2001) 1.17
Loss of heterozygosity analysis: practically and conceptually flawed? Genes Chromosomes Cancer (2002) 1.10
Mutation analysis of the Fanconi anaemia A gene in breast tumours with loss of heterozygosity at 16q24.3. Br J Cancer (1999) 1.06
Different mechanisms of chromosome 16 loss of heterozygosity in well- versus poorly differentiated ductal breast cancer. Genes Chromosomes Cancer (2004) 1.06
Allelic imbalance study of 16q in human primary breast carcinomas using microsatellite markers. Genes Chromosomes Cancer (1995) 1.05
Correlation between karyotypic pattern and clincopathologic features in 125 breast cancer cases. Int J Cancer (1996) 1.04
Deciphering a subgroup of breast carcinomas with putative progression of grade during carcinogenesis revealed by comparative genomic hybridisation (CGH) and immunohistochemistry. Br J Cancer (2004) 1.00
Tumour grade does not change between primary and recurrent mammary carcinoma. Eur J Cancer (1998) 0.99
Allelic imbalance analysis of chromosome 16q shows that grade I and grade III invasive ductal breast cancers follow different genetic pathways. J Pathol (2002) 0.95
The PISSLRE gene: structure, exon skipping, and exclusion as tumor suppressor in breast cancer. Genomics (1999) 0.90
The interaction of oestrogen receptor status and pathological features with adjuvant treatment in relation to survival in patients with operable breast cancer: a retrospective study of 2660 patients. Endocr Relat Cancer (2004) 0.89
Construction of a high-resolution physical and transcription map of chromosome 16q24.3: a region of frequent loss of heterozygosity in sporadic breast cancer. Genomics (1998) 0.88
High-resolution integrated map encompassing the breast cancer loss of heterozygosity region on human chromosome 16q22.1. Genomics (2000) 0.87
Whose hypothesis? Ciphering, sectorials, D lesions, freckles and the operation of Stigler's Law. Cancer Biol Ther (2002) 0.83
The role of E-cadherin in low-grade ductal breast tumourigenesis. J Pathol (2003) 0.79
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nat Genet (1998) 21.52
Racial residential segregation: a fundamental cause of racial disparities in health. Public Health Rep (2002) 13.49
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature (1998) 10.35
Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature (1987) 10.21
Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4. Proc Natl Acad Sci U S A (1988) 7.48
Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J (1986) 6.62
PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet (1999) 6.18
Microarray based comparative genomic hybridisation (array-CGH) detects submicroscopic chromosomal deletions and duplications in patients with learning disability/mental retardation and dysmorphic features. J Med Genet (2004) 5.76
Management of women who test positive for high-risk types of human papillomavirus: the HART study. Lancet (2003) 5.39
Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis. Proc Natl Acad Sci U S A (1998) 5.21
Human papillomavirus testing in primary cervical screening. Lancet (1995) 5.09
Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas. Nat Genet (2001) 4.96
A systematic, high-resolution linkage of the cytogenetic and physical maps of the human genome. Nat Genet (2000) 4.78
The DNA sequence and analysis of human chromosome 6. Nature (2003) 4.75
Growth hormone receptor and serum binding protein: purification, cloning and expression. Nature (1988) 4.40
Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nat Genet (1997) 4.27
Colorectal cancer and genetic alterations in the Wnt pathway. Oncogene (2006) 4.14
Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene. Nat Genet (2000) 4.13
Clinical decision support systems for the practice of evidence-based medicine. J Am Med Inform Assoc (2001) 3.90
Samarium-153-EDTMP biodistribution and dosimetry estimation. J Nucl Med (1993) 3.65
The caregiver reaction assessment (CRA) for caregivers to persons with chronic physical and mental impairments. Res Nurs Health (1992) 3.44
Cancer incidence in the United Kingdom: projections to the year 2030. Br J Cancer (2011) 3.23
Does levodopa accelerate the pathologic process in Parkinson disease brain? Neurology (2011) 3.10
Implementing the patient's charter in outpatient services. BMJ (1992) 2.85
WWOX: a candidate tumor suppressor gene involved in multiple tumor types. Proc Natl Acad Sci U S A (2001) 2.79
The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis. Nat Med (1999) 2.76
Cervical sampling devices. BMJ (1996) 2.74
Developmental surveillance in general practice. Br Med J (1978) 2.71
Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis. Gut (2008) 2.68
Histological grading of breast carcinomas: a study of interobserver agreement. Hum Pathol (1995) 2.63
Sentinel node biopsy in cutaneous melanoma: time for consensus to better inform patient choice. Br J Dermatol (2015) 2.61
Array-CGH detection of micro rearrangements in mentally retarded individuals: clinical significance of imbalances present both in affected children and normal parents. J Med Genet (2005) 2.60
Intra-alveolar haemorrhage in sudden infant death syndrome: a cause for concern? J Clin Pathol (1999) 2.37
Imaging protein kinase Calpha activation in cells. Science (1999) 2.37
Effect of smoking cessation on cervical lesion size. Lancet (1996) 2.35
Why the Scots die younger: synthesizing the evidence. Public Health (2012) 2.34
Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly. Am J Hum Genet (1998) 2.34
A systematic review of the role of human papillomavirus testing within a cervical screening programme. Health Technol Assess (1999) 2.32
Trends in cervical cancer mortality. Lancet (1991) 2.28
Characterization and organization of DNA sequences adjacent to the human telomere associated repeat (TTAGGG)n. Nucleic Acids Res (1990) 2.23
Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes. Hum Mol Genet (1998) 2.21
Genome changes and gene expression in human solid tumors. Carcinogenesis (2000) 2.21
A new immunohistochemical antibody for the assessment of estrogen receptor status on routine formalin-fixed tissue samples. Hum Pathol (1995) 2.20
Morphological features of TMPRSS2-ERG gene fusion prostate cancer. J Pathol (2007) 2.17
Extraordinary stability of enzymes dried in trehalose: simplified molecular biology. Biotechnology (N Y) (1992) 2.17
Allelic imbalance at the LKB1 (STK11) locus in tumours from patients with Peutz-Jeghers' syndrome provides evidence for a hamartoma-(adenoma)-carcinoma sequence. J Pathol (1999) 2.13
Cholesterol-lowering intervention program. Effect of the step I diet in community office practices. Arch Intern Med (1996) 2.11
L-myo-inositol 1,4,5,6-tetrakisphosphate is present in both mammalian and avian cells. Biochem J (1988) 2.10
A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer. J Biol Chem (1999) 2.09
Microsatellite instability and the clinicopathological features of sporadic colorectal cancer. Gut (2001) 2.08
Comparative genomic hybridization of breast tumors stratified by histological grade reveals new insights into the biological progression of breast cancer. Cancer Res (1999) 2.02
Zf9, a Kruppel-like transcription factor up-regulated in vivo during early hepatic fibrosis. Proc Natl Acad Sci U S A (1998) 2.02
The human placental alkaline phosphatase gene and related sequences map to chromosome 2 band q37. Ann Hum Genet (1987) 2.00
Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast. Histopathology (2006) 1.98
Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion. Cancer Res (1993) 1.97
Accelerated decline in cervical cancer mortality in England and Wales. Lancet (1995) 1.95
Non-random association between alleles detected at D4S95 and D4S98 and the Huntington's disease gene. J Med Genet (1989) 1.95
The complex nature of constitutional de novo apparently balanced translocations in patients presenting with abnormal phenotypes. J Med Genet (2005) 1.94
Increased copy number at 20q13 in breast cancer: defining the critical region and exclusion of candidate genes. Cancer Res (1994) 1.93
Preferences for quality of life or survival expressed by patients with heart failure. J Heart Lung Transplant (2001) 1.92
Clinical evaluation of fibreoptic sigmoidoscopy employing the Olympus CF-SB colonoscope. Gut (1971) 1.90
Homologous recombination in hybridoma cells: dependence on time and fragment length. Mol Cell Biol (1990) 1.89
Independent amplification and frequent co-amplification of three nonsyntenic regions on the long arm of chromosome 20 in human breast cancer. Cancer Res (1996) 1.89
Prevalence of restless legs syndrome among men aged 18 to 64 years: an association with somatic disease and neuropsychiatric symptoms. Mov Disord (2001) 1.89
The human homologue for the Caenorhabditis elegans cul-4 gene is amplified and overexpressed in primary breast cancers. Cancer Res (1998) 1.88
Policy implications for implementing evidence-based practices. Psychiatr Serv (2001) 1.87
A journal core list for health administration libraries. Med Ref Serv Q (1984) 1.85
Resident human hepatic lymphocytes are phenotypically different from circulating lymphocytes. J Hepatol (1998) 1.84
Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation. Oncogene (2006) 1.82
Are coroners' necropsies necessary? A prospective study examining whether a "view and grant" system of death certification could be introduced into England and Wales. J Clin Pathol (2001) 1.82
Immunohistochemical detection of steroid receptors in breast cancer: a working protocol. UK Receptor Group, UK NEQAS, The Scottish Breast Cancer Pathology Group, and The Receptor and Biomarker Study Group of the EORTC. J Clin Pathol (2000) 1.81
Providing the ideal surgical service. Ann R Coll Surg Engl (1992) 1.74
Radiation, work experience, and cause specific mortality among workers at an energy research laboratory. Br J Ind Med (1985) 1.73
APC in the regulation of intestinal crypt fission. J Pathol (1998) 1.73
Risk of cutaneous melanoma in relation to the numbers, types and sites of naevi: a case-control study. Br J Cancer (1996) 1.71
Analysis of nucleotide sequences of two ligninase cDNAs from a white-rot filamentous fungus, Phanerochaete chrysosporium. Gene (1987) 1.67
Efficacy of an implanted neuroprosthesis for restoring hand grasp in tetraplegia: a multicenter study. Arch Phys Med Rehabil (2001) 1.67
Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited hamartoma syndromes. Am J Pathol (1998) 1.67
Yeast is unable to excise foreign intervening sequences from hybrid gene transcripts. Proc Natl Acad Sci U S A (1983) 1.67
Acute gastroenteritis in northern Ireland and the Republic of Ireland: a telephone survey. Commun Dis Public Health (2004) 1.66
Isolation of the gene for McLeod syndrome that encodes a novel membrane transport protein. Cell (1994) 1.65
Surgical training, supervision, and service. BMJ (1999) 1.65
SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway. Proc Natl Acad Sci U S A (2001) 1.65
Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast. Int J Cancer (2001) 1.64
Primary cerebral lymphoma and glioblastoma multiforme: differences in diffusion characteristics evaluated with diffusion tensor imaging. AJNR Am J Neuroradiol (2007) 1.64
Prenatal detection of unbalanced chromosomal rearrangements by array CGH. J Med Genet (2005) 1.63
Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q. Hum Mol Genet (2000) 1.62
Mechanisms of inactivation of E-cadherin in breast cancer cell lines. Cancer Res (1998) 1.61
Effect on patient management of a weekend 'on-call' nuclear medicine service. Nucl Med Commun (1994) 1.61
Detection of cross-reactive anti-DNA antibody idiotypes on renal tissue-bound immunoglobulins from lupus patients. J Clin Invest (1985) 1.59
Electron microscopy for the diagnosis of cutaneous viral infections. Br J Dermatol (1970) 1.55
Treadmill aerobic exercise training reduces the energy expenditure and cardiovascular demands of hemiparetic gait in chronic stroke patients. A preliminary report. Stroke (1997) 1.55
Differential expression of keratins 10, 17, and 19 in normal cervical epithelium, cervical intraepithelial neoplasia, and cervical carcinoma. J Clin Pathol (1999) 1.54
Cancer mortality in the United Kingdom: projections to the year 2025. Br J Cancer (2008) 1.52
Refining the Amsterdam Criteria and Bethesda Guidelines: testing algorithms for the prediction of mismatch repair mutation status in the familial cancer clinic. J Clin Oncol (2004) 1.51