Published in Cancer Res on November 15, 1993
Role of p38 MAP Kinase Signal Transduction in Solid Tumors. Genes Cancer (2013) 1.73
Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas. Br J Cancer (1999) 1.71
From antimicrobial to anticancer peptides. A review. Front Microbiol (2013) 1.56
Tumor-specific urinary matrix metalloproteinase fingerprinting: identification of high molecular weight urinary matrix metalloproteinase species. Clin Cancer Res (2008) 1.54
Gelatinase (MMP-2 and -9) expression in gastrointestinal malignancy. Br J Cancer (1998) 1.53
Molecular optical imaging: applications leading to the development of present day therapeutics. NeuroRx (2005) 1.36
Fibronectin activates matrix metalloproteinase-9 secretion via the MEK1-MAPK and the PI3K-Akt pathways in ovarian cancer cells. Clin Exp Metastasis (2000) 1.30
Matrix metalloproteinases and their inhibitors in gastric cancer. Gut (1998) 1.30
Increased expression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma. J Cancer Res Clin Oncol (2003) 1.29
RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth. Int J Cancer (2007) 1.23
Protease-modulated cellular uptake of quantum dots. Nano Lett (2006) 1.19
Comprehensive profiling and localisation of the matrix metalloproteinases in urothelial carcinoma. Br J Cancer (2006) 1.19
MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells. Clin Exp Metastasis (1997) 1.19
Increased expression of collagenase-3 (MMP-13) and MT1-MMP in oesophageal cancer is related to cancer aggressiveness. Gut (2000) 1.14
Photosensitizer-conjugated gold nanorods for enzyme-activatable fluorescence imaging and photodynamic therapy. Theranostics (2012) 1.12
Controlling and switching the morphology of micellar nanoparticles with enzymes. J Am Chem Soc (2011) 1.11
Distinct pattern of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 mRNA expression in human colorectal cancer and liver metastases. Br J Cancer (1995) 1.07
Development of macromolecular prodrug for rheumatoid arthritis. Adv Drug Deliv Rev (2012) 1.07
Macrophage-mediated lymphangiogenesis: the emerging role of macrophages as lymphatic endothelial progenitors. Cancers (Basel) (2012) 1.06
Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells overexpressing epidermal growth factor receptor. Br J Pharmacol (1999) 1.03
Spectrum of matrix metalloproteinase expression in primary and metastatic colon cancer: relationship to the tissue inhibitors of metalloproteinases and membrane type-1-matrix metalloproteinase. Br J Cancer (2001) 1.00
Comparative analysis of the expression patterns of metalloproteinases and their inhibitors in breast neoplasia, sporadic colorectal neoplasia, pulmonary carcinomas and malignant non-Hodgkin's lymphomas in humans. Br J Cancer (1996) 1.00
Revisiting immunosurveillance and immunostimulation: Implications for cancer immunotherapy. J Transl Med (2005) 0.97
Cia5d regulates a new fibroblast-like synoviocyte invasion-associated gene expression signature. Arthritis Res Ther (2008) 0.95
Functional promoter -94 ins/del ATTG polymorphism in NFKB1 gene is associated with bladder cancer risk in a Chinese population. PLoS One (2013) 0.94
CCL7 and CCL21 overexpression in gastric cancer is associated with lymph node metastasis and poor prognosis. World J Gastroenterol (2012) 0.94
Regulation of monocyte MMP-9 production by TNF-alpha and a tumour-derived soluble factor (MMPSF). Br J Cancer (1998) 0.94
MMP7 and MMP8 genetic polymorphisms in bladder cancer patients. Cent European J Urol (2014) 0.94
Gelatinolytic activity of matrix metalloproteinase in tumor tissues correlates with the invasiveness of oral cancer. Clin Exp Metastasis (1999) 0.94
Matrix metalloproteinase-1 is induced by epidermal growth factor in human bladder tumour cell lines and is detectable in urine of patients with bladder tumours. Br J Cancer (1998) 0.93
Biological stimuli and biomolecules in the assembly and manipulation of nanoscale polymeric particles. Chem Sci (2012) 0.93
Transcriptome profiling of a multiple recurrent muscle-invasive urothelial carcinoma of the bladder by deep sequencing. PLoS One (2014) 0.93
Expression of tissue inhibitors of metalloproteinases (TIMPs) in gastric cancer. Dig Dis Sci (2000) 0.88
Increased type-IV collagenase (MMP-2 and MMP-9) activity following preoperative radiotherapy in rectal cancer. Br J Cancer (2000) 0.88
Combined determination of plasma MMP2, MMP9, and TIMP1 improves the non-invasive detection of transitional cell carcinoma of the bladder. BMC Urol (2006) 0.87
Nanoparticles for Improving Cancer Diagnosis. Mater Sci Eng R Rep (2013) 0.87
Matrix Metalloproteinases and Bladder Cancer: What is New? ISRN Urol (2012) 0.85
Unique activation of matrix metalloproteinase-9 within human liver metastasis from colorectal cancer. Br J Cancer (1998) 0.84
Imbalance between serum matrix metalloproteinase-2 and its inhibitor as a predictor of recurrence of urothelial cancer. Br J Cancer (1998) 0.84
Colocalisation of matrix metalloproteinase-9-mRNA and protein in human colorectal cancer stromal cells. Br J Cancer (1996) 0.84
Claudin-4 expression is associated with tumor invasion, MMP-2 and MMP-9 expression in gastric cancer. Exp Ther Med (2010) 0.84
Suppression of matrix metalloproteinase-2 via RNA interference inhibits pancreatic carcinoma cell invasiveness and adhesion. World J Gastroenterol (2009) 0.83
Potential of fluorescent metalloproteinase substrates for cancer detection. Clin Biochem (2011) 0.83
Initial characterization of a dually radiolabeled peptide for simultaneous monitoring of protein targets and enzymatic activity. Nucl Med Biol (2012) 0.83
Molecular substratification of bladder cancer: moving towards individualized patient management. Ther Adv Urol (2016) 0.82
Enhancement of type IV collagenases by highly metastatic variants of HT1080 fibrosarcoma cells established by a transendothelial invasion system in vitro. Clin Exp Metastasis (1998) 0.81
Usefulness of MMP-9/TIMP-1 in predicting tumor recurrence in patients undergoing curative surgical resection for gastric carcinoma. Dig Dis Sci (2007) 0.81
Gynura procumbens ethanolic extract suppresses osteosarcoma cell proliferation and metastasis in vitro. Oncol Lett (2013) 0.81
Characterization of invading glioma cells using molecular analysis of leading-edge tissue. J Korean Neurosurg Soc (2011) 0.81
Matrix metalloproteinases and their inhibitors in canine mammary tumors. BMC Vet Res (2011) 0.81
The effect of a novel frizzled 8-related antiproliferative factor on in vitro carcinoma and melanoma cell proliferation and invasion. Invest New Drugs (2011) 0.81
Tumor cell contact mediated transcriptional activation of the fibroblast matrix metalloproteinase-9 gene: involvement of multiple transcription factors including Ets and an alternating purine-pyrimidine repeat. Clin Exp Metastasis (1998) 0.80
Cassia tora L. (Jue-ming-zi) has anticancer activity in TCA8113 cells in vitro and exerts anti-metastatic effects in vivo. Oncol Lett (2012) 0.80
Full-length L1CAM and not its Δ2Δ27 splice variant promotes metastasis through induction of gelatinase expression. PLoS One (2011) 0.79
Identification of pro-inflammatory cytokines associated with muscle invasive bladder cancer; the roles of IL-5, IL-20, and IL-28A. PLoS One (2012) 0.79
Prostate-specific membrane antigen can promote in vivo osseous metastasis of prostate cancer cells in mice. Braz J Med Biol Res (2012) 0.79
Immunolocalization of matrix metalloproteinases and their inhibitors in clinical specimens of bone metastasis from breast carcinoma. Clin Exp Metastasis (2000) 0.78
Afatinib inhibits proliferation and invasion and promotes apoptosis of the T24 bladder cancer cell line. Exp Ther Med (2015) 0.78
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation. Br J Cancer (2001) 0.78
Expression of TGF-β1, SNAI1 and MMP-9 is associated with lymph node metastasis in papillary thyroid carcinoma. J Mol Histol (2013) 0.78
The role of vascular endothelial growth factor and matrix metalloproteinases in canine lymphoma: in vivo and in vitro study. BMC Vet Res (2013) 0.78
Different matrix micro-environments in colon cancer and diverticular disease. Int J Colorectal Dis (2006) 0.77
Profiling of matrix metalloproteinases and tissue inhibitors of metalloproteinases proteins in bladder urothelial carcinoma. Oncol Lett (2010) 0.77
The biochemical value of urinary metalloproteinases 3 and 9 in diagnosis and prognosis of bladder cancer in Egypt. J Biomed Sci (2014) 0.77
Expression of tissue inhibitors of metalloproteinases (TIMPs) in hepatocellular carcinoma. Korean J Intern Med (2000) 0.77
Claudin-4 expression in gastric cancer cells enhances the invasion and is associated with the increased level of matrix metalloproteinase-2 and -9 expression. Oncol Lett (2014) 0.76
Flavonoids from Orostachys japonicus A. Berger inhibit the invasion of LnCaP prostate carcinoma cells by inactivating Akt and modulating tight junctions. Int J Mol Sci (2013) 0.76
Inorganic sulfur reduces the motility and invasion of MDA-MB-231 human breast cancer cells. Nutr Res Pract (2011) 0.76
From competency to dormancy: a 3D model to study cancer cells and drug responsiveness. J Transl Med (2016) 0.75
Invasiveness of mouse embryos to human ovarian cancer cells HO8910PM and the role of MMP-9. Cancer Cell Int (2012) 0.75
Influence of Immune Myeloid Cells on the Extracellular Matrix During Cancer Metastasis. Cancer Microenviron (2016) 0.75
An animal model of buccal mucosa cancer and cervical lymph node metastasis induced by U14 squamous cell carcinoma cells. Exp Ther Med (2013) 0.75
Stroma targeting nuclear imaging and radiopharmaceuticals. Int J Mol Imaging (2012) 0.75
Aurora Kinase A is a Biomarker for Bladder Cancer Detection and Contributes to its Aggressive Behavior. Sci Rep (2017) 0.75
Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial. Lancet (2004) 12.59
Exposure measurement error in time-series studies of air pollution: concepts and consequences. Environ Health Perspect (2000) 9.30
Molecular genetics of human color vision: the genes encoding blue, green, and red pigments. Science (1986) 8.23
Should paediatric intensive care be centralised? Trent versus Victoria. Lancet (1997) 8.08
Dissection of Mycobacterium tuberculosis antigens using recombinant DNA. Proc Natl Acad Sci U S A (1985) 7.46
Emergence of vancomycin-resistant enterococci in New York City. Lancet (1993) 7.37
Isolation of a tumor factor responsible for angiogenesis. J Exp Med (1971) 7.12
Guidelines for the welfare and use of animals in cancer research. Br J Cancer (2010) 6.97
Rationale and standards for the systematic review of qualitative literature in health services research. Qual Health Res (1998) 6.95
Prevalence of patent foramen ovale in patients with stroke. N Engl J Med (1988) 5.94
A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif. Mol Cell (1998) 5.89
Estimating the burden of musculoskeletal disorders in the community: the comparative prevalence of symptoms at different anatomical sites, and the relation to social deprivation. Ann Rheum Dis (1998) 5.76
Human papillomavirus testing in primary cervical screening. Lancet (1995) 5.09
Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet (1987) 4.97
Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse. Nat Genet (2000) 4.66
Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis. Nat Med (1999) 4.41
Differing patterns of temporal atrophy in Alzheimer's disease and semantic dementia. Neurology (2001) 4.10
Guidelines for the diagnosis and treatment of cholangiocarcinoma: consensus document. Gut (2002) 4.01
Daily sunscreen application and betacarotene supplementation in prevention of basal-cell and squamous-cell carcinomas of the skin: a randomised controlled trial. Lancet (1999) 3.92
Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast. Genes Dev (1998) 3.91
A community training scheme in cardiopulmonary resuscitation. Br Med J (Clin Res Ed) (1984) 3.83
A randomized controlled trial of acetyl salicylic acid in the secondary prevention of mortality from myocardial infarction. Br Med J (1974) 3.80
Mass and molecular composition of vesicular stomatitis virus: a scanning transmission electron microscopy analysis. J Virol (1985) 3.79
Public health research and lay knowledge. Soc Sci Med (1996) 3.72
Isolation, characterization and structure of bacterial flagellar motors containing the switch complex. J Mol Biol (1994) 3.71
Impact of surgery for stress incontinence on morbidity: cohort study. BMJ (1997) 3.70
Sexual health of teenagers in England and Wales: analysis of national data. BMJ (1999) 3.54
Guidelines for the use of fresh-frozen plasma, cryoprecipitate and cryosupernatant. Br J Haematol (2004) 3.52
Prostate Testing for Cancer and Treatment (ProtecT) feasibility study. Health Technol Assess (2003) 3.25
CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc Natl Acad Sci U S A (1997) 3.25
MGDS examination. Br Dent J (1989) 3.21
AREVA: multicenter randomized comparison of low-dose versus standard-dose anticoagulation in patients with mechanical prosthetic heart valves. Circulation (1996) 3.00
Acute lower respiratory tract infections in children: possible criteria for selection of patients for antibiotic therapy and hospital admission. Bull World Health Organ (1984) 2.97
Perivalvular abscesses associated with endocarditis; clinical features and prognostic factors of overall survival in a series of 233 cases. Perivalvular Abscesses French Multicentre Study. Eur Heart J (1999) 2.90
The genesis of chronic illness: narrative re-construction. Sociol Health Illn (1984) 2.87
An invasion-related complex of cortactin, paxillin and PKCmu associates with invadopodia at sites of extracellular matrix degradation. Oncogene (1999) 2.86
Health and wages: evidence on men and women in urban Brazil. J Econom (1997) 2.75
Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B. Mol Cell Biol (1995) 2.69
Met31p and Met32p, two related zinc finger proteins, are involved in transcriptional regulation of yeast sulfur amino acid metabolism. Mol Cell Biol (1997) 2.68
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat Med (2001) 2.66
Correlation of the highest-energy cosmic rays with nearby extragalactic objects. Science (2007) 2.57
Prognostic factors in bile duct carcinoma: analysis of 96 cases. Ann Surg (1981) 2.53
Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes. Blood (2000) 2.53
Barrett's metaplasia. Lancet (2000) 2.47
HPV testing in primary screening of older women. Br J Cancer (1999) 2.44
Nuclear localization of I kappa B alpha promotes active transport of NF-kappa B from the nucleus to the cytoplasm. J Cell Sci (1997) 2.44
Bargaining power within couples and use of prenatal and delivery care in Indonesia. Stud Fam Plann (2001) 2.42
Secondary cancers after bone marrow transplantation for leukemia or aplastic anemia. N Engl J Med (1989) 2.42
Imaging protein kinase Calpha activation in cells. Science (1999) 2.37
Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine. Proc Natl Acad Sci U S A (1996) 2.36
Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia. Clin Cancer Res (2001) 2.35
Desflurane vaporiser contamination. Anaesthesia (2014) 2.35
Spatial analysis of notified dengue fever infections. Epidemiol Infect (2010) 2.34
Nucleation and growth phases in the polymerization of coat and scaffolding subunits into icosahedral procapsid shells. Biophys J (1993) 2.33
Maintenance of remission in ulcerative colitis with oral preparation of 5-aminosalicylic acid. Br Med J (Clin Res Ed) (1982) 2.32
Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells. Mol Cell Biol (1996) 2.31
Randomized trial of a slow-release versus a standard formulation of cytarabine for the intrathecal treatment of lymphomatous meningitis. J Clin Oncol (1999) 2.29
Glucose utilization in vivo by human pulmonary neoplasms. Cancer (1987) 2.29
Early increase of von Willebrand factor predicts adverse outcome in unstable coronary artery disease: beneficial effects of enoxaparin. French Investigators of the ESSENCE Trial. Circulation (1998) 2.28
"Proximal-type" epithelioid sarcoma, a distinctive aggressive neoplasm showing rhabdoid features. Clinicopathologic, immunohistochemical, and ultrastructural study of a series. Am J Surg Pathol (1997) 2.25
Survival trends for patients with AIDS. JAMA (1990) 2.24
Phase I study of bryostatin 1: assessment of interleukin 6 and tumor necrosis factor alpha induction in vivo. The Cancer Research Campaign Phase I Committee. J Natl Cancer Inst (1993) 2.22
Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2. Mech Dev (2001) 2.20
Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins. J Cell Biol (1990) 2.20
C-reactive protein and complement are important mediators of tissue damage in acute myocardial infarction. J Exp Med (1999) 2.17
Three-dimensional transformation of capsids associated with genome packaging in a bacterial virus. J Mol Biol (1993) 2.16
Procedures used in withdrawal of mechanical ventilation. Am J Crit Care (1996) 2.15
The Panton-Valentine leukocidin vaccine protects mice against lung and skin infections caused by Staphylococcus aureus USA300. Clin Microbiol Infect (2008) 2.14
Gemcitabine alone or in combination with cisplatin in patients with advanced or metastatic cholangiocarcinomas or other biliary tract tumours: a multicentre randomised phase II study - The UK ABC-01 Study. Br J Cancer (2009) 2.13
The EPHESUS trial: eplerenone in patients with heart failure due to systolic dysfunction complicating acute myocardial infarction. Eplerenone Post-AMI Heart Failure Efficacy and Survival Study. Cardiovasc Drugs Ther (2001) 2.13
Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine. Cell (1990) 2.12
Dissociation of neutrophil emigration and metabolic activity in lobar pneumonia and bronchiectasis. Eur Respir J (1997) 2.10
A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer. J Biol Chem (1999) 2.09
HIV infection in Manchester, 1959. Lancet (1990) 2.08
Effects of chronic vanadate administration in the STZ-induced diabetic rat. The antihyperglycemic action of vanadate is attributable entirely to its suppression of feeding. Diabetes (1994) 2.07
Cardiff Crohn's disease jubilee: the incidence over 50 years. Gut (1988) 2.05
Inflammatory aneurysms of the abdominal aorta. Br J Surg (1972) 2.05
Measurement issues in environmental epidemiology. Environ Health Perspect (1993) 2.02
Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. EMBO J (2000) 2.02
Comparative genomic hybridization of breast tumors stratified by histological grade reveals new insights into the biological progression of breast cancer. Cancer Res (1999) 2.02
Scaffolding protein regulates the polymerization of P22 coat subunits into icosahedral shells in vitro. J Mol Biol (1988) 1.99
Bladder cancer as a prescribed industrial disease: a guide for clinicians. Br Med J (1980) 1.99
Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast. Histopathology (2006) 1.98
An examination of John Fewster's role in the discovery of smallpox vaccination. J R Coll Physicians Edinb (2015) 1.97
Fullerene-like organization of HIV gag-protein shell in virus-like particles produced by recombinant baculovirus. Virology (1994) 1.95
p53 immunostaining as a marker of malignant disease in diagnostic cytopathology. Lancet (1991) 1.95
Acute release of plasminogen activator inhibitor-1 in ST-segment elevation myocardial infarction predicts mortality. Circulation (2003) 1.94
Advanced carcinoma of the prostate: treatment with a gonadotrophin releasing hormone agonist. Br Med J (Clin Res Ed) (1983) 1.93
Gastric assessment of prospective renal-transplant patients. Lancet (1972) 1.89
In vivo measurement of neutrophil activity in experimental lung inflammation. Am J Respir Crit Care Med (1994) 1.88
Functional characterization of human gamma-aminobutyric acidA receptors containing the alpha 4 subunit. Mol Pharmacol (1996) 1.88
Distribution of genes for trimethoprim and gentamicin resistance in bacteria and their plasmids in a general hospital. J Gen Microbiol (1980) 1.84
Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. Cancer Res (1996) 1.84
Enhancement of clinician workflow with computer order entry. Proc Annu Symp Comput Appl Med Care (1995) 1.84
Multiple transcriptional activation complexes tether the yeast activator Met4 to DNA. EMBO J (1998) 1.84
Cellular immunity in rheumatic diseases. I. Rheumatoid arthritis. Arthritis Rheum (1973) 1.83
Activity of chequerboard combinations of ceftaroline and NXL104 versus beta-lactamase-producing Enterobacteriaceae. J Antimicrob Chemother (2010) 1.83
Latency analysis in epidemiologic studies of occupational exposures: application to the Colorado Plateau uranium miners cohort. Am J Ind Med (1999) 1.80