Published in J Exp Med on February 01, 1991
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol (1998) 5.32
A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture. J Cell Biol (1991) 3.23
Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells. J Exp Med (1992) 2.15
Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses. J Clin Invest (2001) 2.10
Interleukin 1 participates in the development of anti-Listeria responses in normal and SCID mice. Proc Natl Acad Sci U S A (1992) 2.06
Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions. J Cell Biol (1996) 1.90
Differently phosphorylated forms of the cortactin homolog HS1 mediate distinct functions in natural killer cells. Nat Immunol (2008) 1.67
Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma. J Clin Invest (1992) 1.65
Transforming growth factor beta induces rosettes of podosomes in primary aortic endothelial cells. Mol Cell Biol (2006) 1.50
Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4. J Cell Biol (1994) 1.43
Trans-cellular migration: cell-cell contacts get intimate. Curr Opin Cell Biol (2008) 1.42
An essential role for tumor necrosis factor in natural killer cell-mediated tumor rejection in the peritoneum. J Exp Med (1998) 1.36
Cloning and characterization of a new isoform of the interleukin 1 receptor antagonist. J Exp Med (1995) 1.31
NK cells, displaying early activation, cytotoxicity and adhesion molecules, are associated with mild dengue disease. Clin Exp Immunol (2006) 1.22
Role of human natural killer cells in health and disease. Clin Diagn Lab Immunol (1994) 1.19
Tumor cell surface alpha 4 beta 1 integrin mediates adhesion to vascular endothelium: demonstration of an interaction with the N-terminal domains of INCAM-110/VCAM-1. Cell Regul (1991) 1.10
Mutation of putative divalent cation sites in the alpha 4 subunit of the integrin VLA-4: distinct effects on adhesion to CS1/fibronectin, VCAM-1, and invasin. J Cell Biol (1993) 1.06
Settings and mechanisms for trans-cellular diapedesis. Front Biosci (Landmark Ed) (2009) 1.03
Integrin-mediated ras-extracellular regulated kinase (ERK) signaling regulates interferon gamma production in human natural killer cells. J Exp Med (1998) 1.00
Increased interleukin-1 beta and fibronectin expression are early features of the development of the postcardiac transplant coronary arteriopathy in piglets. Am J Pathol (1993) 0.98
Interactions between interleukin-2-activated lymphocytes and vascular endothelium: binding to and migration across specialized and non-specialized endothelia. Immunology (1992) 0.95
Importance of RhoGTPases in formation, characteristics, and functions of invadosomes. Small GTPases (2014) 0.90
Motility and ultrastructure of large granular lymphocytes on lipid bilayers reconstituted with adhesion receptors LFA-1, ICAM-1, and two isoforms of LFA-3. J Cell Biol (1991) 0.89
The effects of beta-adrenoceptor stimulation on adhesion of human natural killer cells to cultured endothelium. Br J Pharmacol (1994) 0.89
Expression of endothelial adhesion molecules in vivo. Increased endothelial ICAM-2 expression in lymphoid malignancies. Am J Pathol (1992) 0.87
Expression and function of alpha 4/beta 7 integrin on human natural killer cells. Immunology (1996) 0.85
Regulated expression of vascular cell adhesion molecule-1 in human malignant melanoma. Am J Pathol (1992) 0.80
Role of cortactin homolog HS1 in transendothelial migration of natural killer cells. PLoS One (2015) 0.79
Detection of cell-adhesion molecules on human liver-associated lymphocytes. Immunology (1994) 0.76
Biology of natural killer cells. Adv Immunol (1989) 14.77
Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu Rev Cell Biol (1988) 14.18
Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science (1989) 10.70
Identification of an inducible endothelial-leukocyte adhesion molecule. Proc Natl Acad Sci U S A (1987) 10.43
Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1). Cell (1987) 9.41
Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell (1989) 9.06
Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines. J Clin Invest (1985) 8.70
A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone. N Engl J Med (1987) 7.33
An inducible endothelial cell surface glycoprotein mediates melanoma adhesion. Science (1989) 4.01
Vascular cell adhesion molecule-1 mediates lymphocyte adherence to cytokine-activated cultured human endothelial cells. Blood (1990) 3.65
Structure and function of leukocyte integrins. Immunol Rev (1990) 3.62
Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes. Exp Cell Res (1985) 3.41
Characterization of the cell surface heterodimer VLA-4 and related peptides. J Biol Chem (1987) 2.94
IL-1 stimulates IL-6 production in endothelial cells. J Immunol (1989) 2.85
Molecular heterogeneity of adherens junctions. J Cell Biol (1985) 2.83
Fibronectin and vitronectin regulate the organization of their respective Arg-Gly-Asp adhesion receptors in cultured human endothelial cells. J Cell Biol (1988) 2.64
Cytokines as communication signals between leukocytes and endothelial cells. Immunol Today (1989) 2.60
A monoclonal antibody that detects a novel antigen on endothelial cells that is induced by tumor necrosis factor, IL-1, or lipopolysaccharide. J Immunol (1990) 2.55
Rous sarcoma virus-transformed fibroblasts and cells of monocytic origin display a peculiar dot-like organization of cytoskeletal proteins involved in microfilament-membrane interactions. Exp Cell Res (1987) 2.40
Cell-substratum interaction of cultured avian osteoclasts is mediated by specific adhesion structures. J Cell Biol (1984) 2.36
T lymphocyte adhesion to endothelial cells: mechanisms demonstrated by anti-LFA-1 monoclonal antibodies. J Immunol (1986) 2.28
Characterization of a novel differentiation antigen complex recognize by a monoclonal antibody (A-1A5): unique activation-specific molecular forms on stimulated T cells. J Immunol (1983) 2.13
Relative contribution of the leukocyte molecules Mo1, LFA-1, and p150,95 (LeuM5) in adhesion of granulocytes and monocytes to vascular endothelium is tissue- and stimulus-specific. J Cell Physiol (1988) 1.88
Expression of transformation-associated protease(s) that degrade fibronectin at cell contact sites. J Cell Biol (1984) 1.71
Increase in NK cell number and turnover rate during acute viral infection. J Immunol (1983) 1.65
Adhesion of T lymphocytes to human endothelial cells is regulated by the LFA-1 membrane molecule. J Cell Physiol (1986) 1.57
Alpha-actinin-containing aggregates in transformed cells are highly dynamic structures. J Cell Biol (1987) 1.56
Interleukin 2-activated human lymphocytes exhibit enhanced adhesion to normal vascular endothelial cells and cause their lysis. J Immunol (1987) 1.49
Both Fc receptors and lymphocyte-function-associated antigen 1 on human T gamma lymphocytes are required for antibody-dependent cellular cytotoxicity (killer cell activity). Eur J Immunol (1984) 1.48
Role of p150,95 in adhesion, migration, chemotaxis and phagocytosis of human monocytes. Eur J Immunol (1987) 1.48
Accumulation and chemotaxis of natural killer/large granular lymphocytes at sites of virus replication. J Immunol (1987) 1.43
Accumulation of natural killer and cytotoxic T large granular lymphocytes in the liver during virus infection. J Exp Med (1986) 1.43
Augmentation of organ-associated natural killer activity by biological response modifiers. Isolation and characterization of large granular lymphocytes from the liver. J Exp Med (1984) 1.41
Functional studies of the domains of talin. J Cell Biol (1990) 1.35
Immunocytochemical distribution of extracellular matrix receptors in human osteoclasts: a beta 3 integrin is colocalized with vinculin and talin in the podosomes of osteoclastoma giant cells. Exp Cell Res (1989) 1.27
Specific release of proteoglycans from human natural killer cells during target lysis. Nature (1985) 1.26
CD11a-c/CD18 and GP84 (LB-2) adhesion molecules on human large granular lymphocytes and their participation in natural killing. J Immunol (1988) 1.22
Phenotypic and functional characterization of lymphocytes that bind human microvascular endothelial cells in vitro. Evidence for preferential binding of natural killer cells. J Clin Invest (1987) 1.14
In vitro migration of human large granular lymphocytes. J Immunol (1985) 1.12
Are "natural killer" cells involved in allograft rejection? Eur J Immunol (1983) 1.08
IL-2 rapidly induces natural killer cell adhesion to human endothelial cells. A potential mechanism for endothelial injury. J Immunol (1988) 0.99
Cytoskeleton and adhesion patterns of cultured chick embryo chondrocytes during cell spreading and Rous sarcoma virus transformation. Exp Cell Res (1984) 0.98
Cytotoxicity of activated monocytes on endothelial cells. J Immunol (1990) 0.98
Chemotaxis of large granular lymphocytes. J Immunol (1986) 0.95
Defective natural killer activity within human ovarian tumors: low numbers of morphologically defined effectors present in situ. J Natl Cancer Inst (1983) 0.91
Modulation of the locomotory capacity of human large granular lymphocytes. Cell Immunol (1986) 0.84
Activated endothelial cells resist lymphokine-activated killer cell-mediated injury. Possible role of induced cytokines in limiting capillary leak during IL-2 therapy. J Immunol (1989) 0.83
Activated adherent large granular lymphocytes/natural killer (LGL/NK) cells change their migratory behaviour. Immunology (1988) 0.78
Inflammation and cancer: back to Virchow? Lancet (2001) 27.40
Control of apoptosis and mitotic spindle checkpoint by survivin. Nature (1998) 8.60
Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J Exp Med (1998) 8.56
Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis. Cell (1999) 7.33
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science (2000) 6.26
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol (1998) 5.32
Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood (1996) 5.31
Tumor necrosis factor is chemotactic for monocytes and polymorphonuclear leukocytes. J Immunol (1987) 4.75
Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J Leukoc Biol (2009) 4.53
Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. Immunity (1997) 4.19
Pleiotropic cell-division defects and apoptosis induced by interference with survivin function. Nat Cell Biol (1999) 4.11
Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products. Blood (1992) 4.11
Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. J Immunol (2000) 4.07
Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion? J Clin Invest (1997) 3.93
A novel endothelial-specific membrane protein is a marker of cell-cell contacts. J Cell Biol (1992) 3.85
Role of PML in cell growth and the retinoic acid pathway. Science (1998) 3.82
Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells. J Cell Sci (1998) 3.80
PML is essential for multiple apoptotic pathways. Nat Genet (1998) 3.75
The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6). J Exp Med (1998) 3.70
Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science (1993) 3.62
Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J Biol Chem (1999) 3.53
Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo. Proc Natl Acad Sci U S A (1999) 3.49
Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin. Proc Natl Acad Sci U S A (2000) 3.44
Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes. Exp Cell Res (1985) 3.41
Monoclonal antibodies specific for endothelial cells of mouse blood vessels. Their application in the identification of adult and embryonic endothelium. Eur J Cell Biol (1994) 3.31
The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin). J Cell Biol (1995) 3.27
Cytokine regulation of endothelial cell function. FASEB J (1992) 3.00
Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps. Blood (1996) 2.94
IL-1 stimulates IL-6 production in endothelial cells. J Immunol (1989) 2.85
Selective up-regulation of chemokine receptors CCR4 and CCR8 upon activation of polarized human type 2 Th cells. J Immunol (1998) 2.84
Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system. Blood (1996) 2.76
Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties. J Immunol (1998) 2.70
Interleukin 1 signaling occurs exclusively via the type I receptor. Proc Natl Acad Sci U S A (1993) 2.67
Fibronectin and vitronectin regulate the organization of their respective Arg-Gly-Asp adhesion receptors in cultured human endothelial cells. J Cell Biol (1988) 2.64
Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells. J Cell Biol (1994) 2.63
Cytokines as communication signals between leukocytes and endothelial cells. Immunol Today (1989) 2.60
Catenin-dependent and -independent functions of vascular endothelial cadherin. J Biol Chem (1995) 2.40
Rous sarcoma virus-transformed fibroblasts and cells of monocytic origin display a peculiar dot-like organization of cytoskeletal proteins involved in microfilament-membrane interactions. Exp Cell Res (1987) 2.40
Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line. J Exp Med (1990) 2.40
Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells. J Exp Med (1997) 2.37
Cell-substratum interaction of cultured avian osteoclasts is mediated by specific adhesion structures. J Cell Biol (1984) 2.36
Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10. J Exp Med (1996) 2.36
Granulocyte- and granulocyte-macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate. Nature (1989) 2.25
Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin. Arterioscler Thromb Vasc Biol (1995) 2.25
PTX3, A prototypical long pentraxin, is an early indicator of acute myocardial infarction in humans. Circulation (2000) 2.19
Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages. J Immunol (2000) 2.17
A general strategy for isolation of endothelial cells from murine tissues. Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implants. Arterioscler Thromb Vasc Biol (1997) 2.15
Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells. J Exp Med (1992) 2.15
Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin. J Biol Chem (2000) 2.13
Prostacyclin synthesis induced in vascular cells by interleukin-1. Science (1985) 2.13
Monocyte chemotactic and activating factor gene expression induced in endothelial cells by IL-1 and tumor necrosis factor. J Immunol (1990) 2.10
Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses. J Clin Invest (2001) 2.10
Interleukin-1-inducible genes in endothelial cells. Cloning of a new gene related to C-reactive protein and serum amyloid P component. J Biol Chem (1992) 2.08
Differential localization of VE- and N-cadherins in human endothelial cells: VE-cadherin competes with N-cadherin for junctional localization. J Cell Biol (1998) 2.08
Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines. J Immunol (1995) 2.06
Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines. J Immunol (1997) 2.02
Uncoupling of inflammatory chemokine receptors by IL-10: generation of functional decoys. Nat Immunol (2000) 2.01
Induction of natural killer cell migration by monocyte chemotactic protein-1, -2 and -3. Eur J Immunol (1994) 2.01
Rapid killing of actinomycin D-treated tumor cells by human mononuclear cells. I. Effectors belong to the monocyte-macrophage lineage. J Immunol (1984) 2.01
Cell confluence regulates tyrosine phosphorylation of adherens junction components in endothelial cells. J Cell Sci (1997) 2.01
Survivin apoptosis: an interloper between cell death and cell proliferation in cancer. Lab Invest (1999) 2.00
Detection of phosphotyrosine-containing proteins in the detergent-insoluble fraction of RSV-transformed fibroblasts by azobenzene phosphonate antibodies. EMBO J (1984) 1.98
Bacterial lipopolysaccharide rapidly inhibits expression of C-C chemokine receptors in human monocytes. J Exp Med (1997) 1.97
Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component. J Biol Chem (1997) 1.97
Regulation of the VLA integrin-ligand interactions through the beta 1 subunit. J Cell Biol (1992) 1.96
Systemic anti-inflammatory mediators in COPD: increase in soluble interleukin 1 receptor II during treatment of exacerbations. Thorax (2001) 1.94
Regulation of cadherin function by Rho and Rac: modulation by junction maturation and cellular context. Mol Biol Cell (1999) 1.94
Heterogeneity of endothelial cells. Specific markers. Arterioscler Thromb Vasc Biol (1997) 1.94
Molecular mechanisms of blood vessel formation. Trends Biochem Sci (1997) 1.93
The detection and localization of monocyte chemoattractant protein-1 (MCP-1) in human ovarian cancer. J Clin Invest (1995) 1.91
Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment. Clin Exp Immunol (2012) 1.90
Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions. J Cell Biol (1996) 1.90
Inflammatory bowel disease and intestinal cancer: a paradigm of the Yin-Yang interplay between inflammation and cancer. Oncogene (2010) 1.88
Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing. J Cell Biol (1995) 1.85
The role of integrins in the maintenance of endothelial monolayer integrity. J Cell Biol (1991) 1.85
Targeted null-mutation in the vascular endothelial-cadherin gene impairs the organization of vascular-like structures in embryoid bodies. Proc Natl Acad Sci U S A (1997) 1.84
Cytolytic and cytostatic activity on tumor cells of circulating human monocytes. Int J Cancer (1979) 1.84
Regulation of the macrophage content of neoplasms by chemoattractants. Science (1983) 1.83
Hypertension-associated point mutations in the adducin alpha and beta subunits affect actin cytoskeleton and ion transport. J Clin Invest (1996) 1.83
The type II 'decoy' receptor: a novel regulatory pathway for interleukin 1. Immunol Today (1994) 1.83
Cardiomyocytes induce endothelial cells to trans-differentiate into cardiac muscle: implications for myocardium regeneration. Proc Natl Acad Sci U S A (2001) 1.81
Human cytomegalovirus infection of the major leukocyte subpopulations and evidence for initial viral replication in polymorphonuclear leukocytes from viremic patients. J Infect Dis (1992) 1.81
Histamine induces tyrosine phosphorylation of endothelial cell-to-cell adherens junctions. Arterioscler Thromb Vasc Biol (1999) 1.81
Recombinant human interleukin 5 is a selective eosinophil chemoattractant. Eur J Immunol (1989) 1.80
Interaction between fibrinogen and cultured endothelial cells. Induction of migration and specific binding. J Clin Invest (1985) 1.79