Published in Nat Chem Biol on May 28, 2006
Coordination chemistry of bacterial metal transport and sensing. Chem Rev (2009) 2.65
Copper metallochaperones. Annu Rev Biochem (2010) 2.27
A cytosolic iron chaperone that delivers iron to ferritin. Science (2008) 2.00
Structural biology of copper trafficking. Chem Rev (2009) 1.89
Affinity gradients drive copper to cellular destinations. Nature (2010) 1.82
Three-dimensional structure of the human copper transporter hCTR1. Proc Natl Acad Sci U S A (2009) 1.79
Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport. Nature (2010) 1.76
Unusual Cu(I)/Ag(I) coordination of Escherichia coli CusF as revealed by atomic resolution crystallography and X-ray absorption spectroscopy. Protein Sci (2007) 1.71
Molecular insights into the metal selectivity of the copper(I)-sensing repressor CsoR from Bacillus subtilis. Biochemistry (2009) 1.29
The knowledge-integrated network biomarkers discovery for major adverse cardiac events. J Proteome Res (2008) 1.27
Biochemical basis of regulation of human copper-transporting ATPases. Arch Biochem Biophys (2007) 1.21
Mechanistic comparison of human high-affinity copper transporter 1-mediated transport between copper ion and cisplatin. Mol Pharmacol (2009) 1.19
Metal binding domains 3 and 4 of the Wilson disease protein: solution structure and interaction with the copper(I) chaperone HAH1. Biochemistry (2008) 1.18
Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function. Proc Natl Acad Sci U S A (2014) 1.09
Metal preferences and metallation. J Biol Chem (2014) 1.08
Human Sco1 functional studies and pathological implications of the P174L mutant. Proc Natl Acad Sci U S A (2006) 1.08
Interactions between CusF and CusB identified by NMR spectroscopy and chemical cross-linking coupled to mass spectrometry. Biochemistry (2011) 1.08
Structural organization of human Cu-transporting ATPases: learning from building blocks. J Biol Inorg Chem (2009) 1.05
An NMR study of the interaction of the N-terminal cytoplasmic tail of the Wilson disease protein with copper(I)-HAH1. J Biol Chem (2009) 1.04
Mitochondrial copper metabolism and delivery to cytochrome c oxidase. IUBMB Life (2008) 1.02
The mechanism of Cu+ transport ATPases: interaction with CU+ chaperones and the role of transient metal-binding sites. J Biol Chem (2012) 1.00
"Pulling the plug" on cellular copper: the role of mitochondria in copper export. Biochim Biophys Acta (2008) 0.95
Human superoxide dismutase 1 (hSOD1) maturation through interaction with human copper chaperone for SOD1 (hCCS). Proc Natl Acad Sci U S A (2012) 0.94
Thermodynamics of copper and zinc distribution in the cyanobacterium Synechocystis PCC 6803. Proc Natl Acad Sci U S A (2011) 0.94
Flexibility of the metal-binding region in apo-cupredoxins. Proc Natl Acad Sci U S A (2012) 0.92
Interaction between cyanobacterial copper chaperone Atx1 and zinc homeostasis. J Biol Inorg Chem (2009) 0.91
Structure of the hemoglobin-IsdH complex reveals the molecular basis of iron capture by Staphylococcus aureus. J Biol Chem (2014) 0.90
COX19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux. Mol Biol Cell (2013) 0.90
Tryptophan Cu(I)-pi interaction fine-tunes the metal binding properties of the bacterial metallochaperone CusF. J Biol Inorg Chem (2009) 0.89
Copper binding to the Alzheimer's disease amyloid precursor protein. Eur Biophys J (2007) 0.88
Toward a molecular understanding of metal transport by P(1B)-type ATPases. Curr Top Membr (2012) 0.87
Metals in the "omics" world: copper homeostasis and cytochrome c oxidase assembly in a new light. J Biol Inorg Chem (2007) 0.87
Conserved residues modulate copper release in human copper chaperone Atox1. Proc Natl Acad Sci U S A (2008) 0.87
The Janus face of copper: its expanding roles in biology and the pathophysiology of disease. Meeting on Copper and Related Metals in Biology. EMBO Rep (2007) 0.87
[2Fe-2S] cluster transfer in iron-sulfur protein biogenesis. Proc Natl Acad Sci U S A (2014) 0.86
Structure and interactions of the C-terminal metal binding domain of Archaeoglobus fulgidus CopA. Proteins (2010) 0.86
Atox1 contains positive residues that mediate membrane association and aid subsequent copper loading. J Membr Biol (2013) 0.86
Interplay between glutathione, Atx1 and copper. 1. Copper(I) glutathionate induced dimerization of Atx1. J Biol Inorg Chem (2007) 0.86
In vitro thermodynamic dissection of human copper transfer from chaperone to target protein. PLoS One (2012) 0.86
Tryptophan scanning analysis of the membrane domain of CTR-copper transporters. J Membr Biol (2010) 0.86
Determinants for simultaneous binding of copper and platinum to human chaperone Atox1: hitchhiking not hijacking. PLoS One (2013) 0.85
Mechanism of ATPase-mediated Cu+ export and delivery to periplasmic chaperones: the interaction of Escherichia coli CopA and CusF. J Biol Chem (2014) 0.85
An expanding range of functions for the copper chaperone/antioxidant protein Atox1. Antioxid Redox Signal (2013) 0.83
Probing the coordination environment of the human copper chaperone HAH1: characterization of Hg(II)-bridged homodimeric species in solution. Chemistry (2013) 0.82
Relating dynamic protein interactions of metallochaperones with metal transfer at the single-molecule level. Faraday Discuss (2011) 0.81
T versus D in the MTCXXC motif of copper transport proteins plays a role in directional metal transport. J Biol Inorg Chem (2014) 0.81
Multiple metal binding domains enhance the Zn(II) selectivity of the divalent metal ion transporter AztA. Biochemistry (2007) 0.81
Mapping protein-protein interaction by 13C'-detected heteronuclear NMR spectroscopy. J Biomol NMR (2006) 0.81
Loop recognition and copper-mediated disulfide reduction underpin metal site assembly of CuA in human cytochrome oxidase. Proc Natl Acad Sci U S A (2015) 0.80
Dynamic multibody protein interactions suggest versatile pathways for copper trafficking. J Am Chem Soc (2012) 0.79
Crosstalk between Cu(I) and Zn(II) homeostasis via Atx1 and cognate domains. Chem Commun (Camb) (2013) 0.79
Enthalpy-entropy compensation at play in human copper ion transfer. Sci Rep (2015) 0.78
Heterogeneity in the Histidine-brace Copper Coordination Sphere in Auxiliary Activity Family 10 (AA10) Lytic Polysaccharide Monooxygenases. J Biol Chem (2016) 0.78
Visualizing tricoordinate copper transfer. Nat Chem Biol (2006) 0.78
Identification of New Potential Interaction Partners for Human Cytoplasmic Copper Chaperone Atox1: Roles in Gene Regulation? Int J Mol Sci (2015) 0.78
Metal-binding loop length and not sequence dictates structure. Proc Natl Acad Sci U S A (2009) 0.78
The Structure of the Complex between Yeast Frataxin and Ferrochelatase: CHARACTERIZATION AND PRE-STEADY STATE REACTION OF FERROUS IRON DELIVERY AND HEME SYNTHESIS. J Biol Chem (2016) 0.77
Single-molecule dynamics and mechanisms of metalloregulators and metallochaperones. Biochemistry (2013) 0.77
Interplay between glutathione, Atx1 and copper: X-ray absorption spectroscopy determination of Cu(I) environment in an Atx1 dimer. J Biol Inorg Chem (2008) 0.76
Copper trafficking in biology: an NMR approach. HFSP J (2009) 0.76
Nuclear magnetic resonance signal chemical shifts and molecular simulations: a multidisciplinary approach to modeling copper protein structures. J Biol Inorg Chem (2011) 0.76
Insights into Cu(I) exchange in HAH1 using quantum mechanical and molecular simulations. Biochemistry (2007) 0.76
Addressing the Role of Conformational Diversity in Protein Structure Prediction. PLoS One (2016) 0.76
Disease-causing point-mutations in metal-binding domains of Wilson disease protein decrease stability and increase structural dynamics. Biometals (2016) 0.75
Copper Trafficking in Plants and Its Implication on Cell Wall Dynamics. Front Plant Sci (2016) 0.75
Metal Ions Effectively Ablate the Action of Botulinum Neurotoxin A. J Am Chem Soc (2017) 0.75
A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell (2009) 6.03
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell (2011) 5.06
A MicroRNA targeting dicer for metastasis control. Cell (2010) 4.81
Metal ions in biological catalysis: from enzyme databases to general principles. J Biol Inorg Chem (2008) 2.87
Rational design of a meningococcal antigen inducing broad protective immunity. Sci Transl Med (2011) 2.59
CASD-NMR: critical assessment of automated structure determination by NMR. Nat Methods (2009) 2.50
SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors. Nature (2012) 2.46
Counting the zinc-proteins encoded in the human genome. J Proteome Res (2006) 2.38
Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Proc Natl Acad Sci U S A (2007) 2.16
Zinc through the three domains of life. J Proteome Res (2006) 2.11
Evidence of different metabolic phenotypes in humans. Proc Natl Acad Sci U S A (2008) 2.06
A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells. Blood (2011) 2.03
Solution structure of Sco1: a thioredoxin-like protein Involved in cytochrome c oxidase assembly. Structure (2003) 2.01
The unusually stable quaternary structure of human Cu,Zn-superoxide dismutase 1 is controlled by both metal occupancy and disulfide status. J Biol Chem (2004) 1.97
A Pin1/mutant p53 axis promotes aggressiveness in breast cancer. Cancer Cell (2011) 1.95
Perspectives on NMR in drug discovery: a technique comes of age. Nat Rev Drug Discov (2008) 1.95
Toll-like receptor 2 regulates intestinal inflammation by controlling integrity of the enteric nervous system. Gastroenterology (2013) 1.83
Affinity gradients drive copper to cellular destinations. Nature (2010) 1.82
Folding studies of Cox17 reveal an important interplay of cysteine oxidation and copper binding. Structure (2005) 1.81
Metallochaperones and metal-transporting ATPases: a comparative analysis of sequences and structures. Genome Res (2002) 1.80
A new structural model of Aβ40 fibrils. J Am Chem Soc (2011) 1.78
Quantitative imaging of the T cell antitumor response by positron-emission tomography. Proc Natl Acad Sci U S A (2003) 1.60
MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria. Nat Struct Mol Biol (2009) 1.60
Protonless NMR experiments for sequence-specific assignment of backbone nuclei in unfolded proteins. J Am Chem Soc (2006) 1.54
Metalloproteomes: a bioinformatic approach. Acc Chem Res (2009) 1.52
A copper(I) protein possibly involved in the assembly of CuA center of bacterial cytochrome c oxidase. Proc Natl Acad Sci U S A (2005) 1.52
NMR spectroscopy of paramagnetic metalloproteins. Chembiochem (2005) 1.50
NMR reveals pathway for ferric mineral precursors to the central cavity of ferritin. Proc Natl Acad Sci U S A (2009) 1.48
Structure of human Wilson protein domains 5 and 6 and their interplay with domain 4 and the copper chaperone HAH1 in copper uptake. Proc Natl Acad Sci U S A (2006) 1.47
A redox switch in CopC: an intriguing copper trafficking protein that binds copper(I) and copper(II) at different sites. Proc Natl Acad Sci U S A (2003) 1.46
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer. Nat Cell Biol (2009) 1.44
Acycloguanosyl 5'-thymidyltriphosphate, a thymidine analogue prodrug activated by telomerase, reduces pancreatic tumor growth in mice. Gastroenterology (2010) 1.44
Solution structure of Apo Cu,Zn superoxide dismutase: role of metal ions in protein folding. Biochemistry (2003) 1.44
Metabolomics: available results, current research projects in breast cancer, and future applications. J Clin Oncol (2007) 1.42
Solution structure of human beta-parvalbumin and structural comparison with its paralog alpha-parvalbumin and with their rat orthologs. Biochemistry (2004) 1.41
A large dust/ice ratio in the nucleus of comet 9P/Tempel 1. Nature (2005) 1.40
Solution structure and intermolecular interactions of the third metal-binding domain of ATP7A, the Menkes disease protein. J Biol Chem (2006) 1.40
Conformational space of flexible biological macromolecules from average data. J Am Chem Soc (2010) 1.39
Italy must invest more in science and technology. Nature (2008) 1.38
Individual human phenotypes in metabolic space and time. J Proteome Res (2009) 1.29
HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness. Oncotarget (2013) 1.29
SOD1 and amyotrophic lateral sclerosis: mutations and oligomerization. PLoS One (2008) 1.27
A novel intermembrane space-targeting signal docks cysteines onto Mia40 during mitochondrial oxidative folding. J Cell Biol (2009) 1.26
A hint to search for metalloproteins in gene banks. Bioinformatics (2004) 1.25
Occurrence of copper proteins through the three domains of life: a bioinformatic approach. J Proteome Res (2007) 1.24
13C direct detection experiments on the paramagnetic oxidized monomeric copper, zinc superoxide dismutase. J Am Chem Soc (2003) 1.23
Metal-MACiE: a database of metals involved in biological catalysis. Bioinformatics (2009) 1.23
A hint for the function of human Sco1 from different structures. Proc Natl Acad Sci U S A (2006) 1.23
High-resolution NMR studies of the zinc-binding site of the Alzheimer's amyloid beta-peptide. FEBS J (2007) 1.22
Complete assignment of heteronuclear protein resonances by protonless NMR spectroscopy. Angew Chem Int Ed Engl (2005) 1.22
Fast resonance assignment and fold determination of human superoxide dismutase by high-resolution proton-detected solid-state MAS NMR spectroscopy. Angew Chem Int Ed Engl (2011) 1.21
Cytochrome c: occurrence and functions. Chem Rev (2006) 1.21
A structural-dynamical characterization of human Cox17. J Biol Chem (2007) 1.20
Cellular copper distribution: a mechanistic systems biology approach. Cell Mol Life Sci (2010) 1.18
Metal binding domains 3 and 4 of the Wilson disease protein: solution structure and interaction with the copper(I) chaperone HAH1. Biochemistry (2008) 1.18
Epitope mapping of a bactericidal monoclonal antibody against the factor H binding protein of Neisseria meningitidis. J Mol Biol (2008) 1.17
Solid-state NMR spectroscopy of a paramagnetic protein: assignment and study of human dimeric oxidized CuII-ZnII superoxide dismutase (SOD). Angew Chem Int Ed Engl (2007) 1.17
Mechanism of Cu(A) assembly. Nat Chem Biol (2008) 1.17
Molecular chaperone function of Mia40 triggers consecutive induced folding steps of the substrate in mitochondrial protein import. Proc Natl Acad Sci U S A (2010) 1.16
Solution structure of CopC: a cupredoxin-like protein involved in copper homeostasis. Structure (2002) 1.15
Paramagnetism-based restraints for Xplor-NIH. J Biomol NMR (2004) 1.15
Human TCR that incorporate CD3zeta induce highly preferred pairing between TCRalpha and beta chains following gene transfer. J Immunol (2008) 1.15
Standard operating procedures for pre-analytical handling of blood and urine for metabolomic studies and biobanks. J Biomol NMR (2011) 1.15
High-field dynamic nuclear polarization with high-spin transition metal ions. J Am Chem Soc (2011) 1.15
Molecular recognition and substrate mimicry drive the electron-transfer process between MIA40 and ALR. Proc Natl Acad Sci U S A (2011) 1.14
A method for C(alpha) direct-detection in protonless NMR. J Magn Reson (2007) 1.13
Solution structure of the apo and copper(I)-loaded human metallochaperone HAH1. Biochemistry (2004) 1.13
pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins. Nucleic Acids Res (2013) 1.13
Structural and dynamic aspects related to oligomerization of apo SOD1 and its mutants. Proc Natl Acad Sci U S A (2009) 1.12