Published in Nat Cell Biol on January 18, 2009
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Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast. EMBO Mol Med (2013) 0.94
Pin1 modulates p63α protein stability in regulation of cell survival, proliferation and tumor formation. Cell Death Dis (2013) 0.93
Prolyl isomerase Pin1 downregulates tumor suppressor RUNX3 in breast cancer. Oncogene (2012) 0.93
Late SV40 factor: a key mediator of Notch signaling in human hepatocarcinogenesis. World J Gastroenterol (2011) 0.93
Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin beta-subunit gene transcription. Mol Cell Biol (2009) 0.91
Novel regulation of CD80/CD86-induced phosphatidylinositol 3-kinase signaling by NOTCH1 protein in interleukin-6 and indoleamine 2,3-dioxygenase production by dendritic cells. J Biol Chem (2014) 0.91
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Prolyl isomerase Pin1 regulates mouse embryonic fibroblast differentiation into adipose cells. PLoS One (2012) 0.87
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The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target. Nat Rev Cancer (2016) 0.84
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The cellular peptidyl-prolyl cis/trans isomerase Pin1 regulates reactivation of Kaposi's sarcoma-associated herpesvirus from latency. J Virol (2013) 0.78
Notch signaling in pediatric soft tissue sarcomas. BMC Med (2012) 0.77
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UXT potentiates angiogenesis by attenuating Notch signaling. Development (2015) 0.77
Chemical or genetic Pin1 inhibition exerts potent anticancer activity against hepatocellular carcinoma by blocking multiple cancer-driving pathways. Sci Rep (2017) 0.76
Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression. Oncogene (2016) 0.76
Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis. Nucleic Acids Res (2014) 0.76
Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis. Neoplasia (2017) 0.75
The CSL proteins, versatile transcription factors and context dependent corepressors of the notch signaling pathway. Cell Div (2016) 0.75
PIN1 in breast development and cancer: a clinical perspective. Cell Death Differ (2016) 0.75
A Presenilin-2-ARF4 trafficking axis modulates Notch signaling during epidermal differentiation. J Cell Biol (2016) 0.75
NOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex. Cell Rep (2016) 0.75
Neighboring phosphoSer-Pro motifs in the undefined domain of IRAK1 impart bivalent advantage for Pin1 binding. FEBS J (2016) 0.75
Cyclosporin a disrupts notch signaling and vascular lumen maintenance. PLoS One (2015) 0.75
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Dynamic regulation of Pin1 expression and function during zebrafish development. PLoS One (2017) 0.75
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Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis. EMBO J (2004) 1.62
Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium. Am J Pathol (2004) 1.59
Pin1 links the activities of c-Abl and p300 in regulating p73 function. Mol Cell (2004) 1.55
Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation. Chem Biol (2003) 1.47
Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth. Am J Pathol (2007) 1.36
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