Published in Traffic on May 25, 2006
Intracellular traffic of the K+ channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins. J Physiol (2009) 1.18
Transcriptomics-based identification of novel factors enhancing heterologous protein secretion in yeasts. Appl Environ Microbiol (2007) 1.12
Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions. BMC Genomics (2007) 1.09
Novel cargo-binding site in the beta and delta subunits of coatomer. J Cell Biol (2007) 1.00
In vivo functional specificity and homeostasis of Drosophila 14-3-3 proteins. Genetics (2007) 0.96
Modular TRAPP complexes regulate intracellular protein trafficking through multiple Ypt/Rab GTPases in Saccharomyces cerevisiae. Genetics (2012) 0.93
The yeast 14-3-3 proteins BMH1 and BMH2 differentially regulate rapamycin-mediated transcription. Biosci Rep (2014) 0.82
Sec23 homolog Nel1 is a novel GTPase-activating protein for Sar1 but does not function as a subunit of the coat protein complex II (COPII) coat. J Biol Chem (2014) 0.76
Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science (2009) 4.58
The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell (2008) 3.51
Structure of a complex between a voltage-gated calcium channel beta-subunit and an alpha-subunit domain. Nature (2004) 3.04
Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. EMBO J (2002) 3.03
Consensus-derived structural determinants of the ankyrin repeat motif. Proc Natl Acad Sci U S A (2002) 2.87
Chaperone network in the yeast cytosol: Hsp110 is revealed as an Hsp70 nucleotide exchange factor. EMBO J (2006) 2.45
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1. Mol Cell (2003) 2.25
Characterisation of the passive permeability barrier of nuclear pore complexes. EMBO J (2009) 2.21
Insights into voltage-gated calcium channel regulation from the structure of the CaV1.2 IQ domain-Ca2+/calmodulin complex. Nat Struct Mol Biol (2005) 2.18
Distinct targeting pathways for the membrane insertion of tail-anchored (TA) proteins. J Cell Sci (2008) 2.11
Hide and run. Arginine-based endoplasmic-reticulum-sorting motifs in the assembly of heteromultimeric membrane proteins. EMBO Rep (2005) 2.04
Allosteric regulation of Hsp70 chaperones involves a conserved interdomain linker. J Biol Chem (2006) 1.90
Allosteric regulation of Hsp70 chaperones by a proline switch. Mol Cell (2006) 1.88
The pore helix dipole has a minor role in inward rectifier channel function. Neuron (2005) 1.86
Structure and dynamics of the ATP-bound open conformation of Hsp70 chaperones. Mol Cell (2012) 1.84
Structural insight into KCNQ (Kv7) channel assembly and channelopathy. Neuron (2007) 1.81
14-3-3 dimers probe the assembly status of multimeric membrane proteins. Curr Biol (2003) 1.79
Amide hydrogen exchange reveals conformational changes in hsp70 chaperones important for allosteric regulation. J Biol Chem (2006) 1.78
Bat3 promotes the membrane integration of tail-anchored proteins. J Cell Sci (2010) 1.71
Cross-monomer substrate contacts reposition the Hsp90 N-terminal domain and prime the chaperone activity. J Mol Biol (2011) 1.66
Three-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamer. Nat Struct Mol Biol (2006) 1.64
Biogenesis of tail-anchored proteins: the beginning for the end? J Cell Sci (2009) 1.64
Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine. EMBO J (2009) 1.62
Electrochemical coupling in the voltage-dependent phosphatase Ci-VSP. Nat Chem Biol (2010) 1.59
Mechanics of Hsp70 chaperones enables differential interaction with client proteins. Nat Struct Mol Biol (2011) 1.54
Allostery in the Hsp70 chaperone proteins. Top Curr Chem (2013) 1.52
Molecular basis for regulation of the heat shock transcription factor sigma32 by the DnaK and DnaJ chaperones. Mol Cell (2008) 1.51
Asc1p, a WD40-domain containing adaptor protein, is required for the interaction of the RNA-binding protein Scp160p with polysomes. Biochem J (2004) 1.46
Hsp110 is a nucleotide-activated exchange factor for Hsp70. J Biol Chem (2008) 1.45
Dimerization of the human E3 ligase CHIP via a coiled-coil domain is essential for its activity. J Biol Chem (2003) 1.39
Chemical informatics and target identification in a zebrafish phenotypic screen. Nat Chem Biol (2011) 1.37
Multiple modalities converge on a common gate to control K2P channel function. EMBO J (2011) 1.34
Human heat shock protein 70 enhances tumor antigen presentation through complex formation and intracellular antigen delivery without innate immune signaling. J Biol Chem (2007) 1.33
SEC18/NSF-independent, protein-sorting pathway from the yeast cortical ER to the plasma membrane. J Cell Biol (2005) 1.33
Coiled coils direct assembly of a cold-activated TRP channel. Neuron (2006) 1.33
Dynamics of trigger factor interaction with translating ribosomes. J Biol Chem (2007) 1.28
A size barrier limits protein diffusion at the cell surface to generate lipid-rich myelin-membrane sheets. Dev Cell (2011) 1.28
Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes. EMBO J (2012) 1.27
Amyloid-like interactions within nucleoporin FG hydrogels. Proc Natl Acad Sci U S A (2010) 1.26
Asna1/TRC40-mediated membrane insertion of tail-anchored proteins. J Cell Sci (2010) 1.26
14-3-3 proteins in membrane protein transport. Biol Chem (2006) 1.25
X-ray crystal structure of a TRPM assembly domain reveals an antiparallel four-stranded coiled-coil. J Mol Biol (2008) 1.24
Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins. Proc Natl Acad Sci U S A (2011) 1.23
Mapping temperature-induced conformational changes in the Escherichia coli heat shock transcription factor sigma 32 by amide hydrogen exchange. J Biol Chem (2003) 1.23
Human and yeast Hsp110 chaperones exhibit functional differences. FEBS Lett (2005) 1.22
Deuteration distribution estimation with improved sequence coverage for HX/MS experiments. Bioinformatics (2010) 1.22
Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain. Nat Struct Mol Biol (2009) 1.22
Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation. Structure (2008) 1.21
Posttranscriptional control of quorum-sensing-dependent virulence genes by DksA in Pseudomonas aeruginosa. J Bacteriol (2003) 1.21
The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol. J Biol Chem (2005) 1.19
Biosynthetic FGF-2 is targeted to non-lipid raft microdomains following translocation to the extracellular surface of CHO cells. J Cell Sci (2002) 1.19
Intracellular traffic of the K+ channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins. J Physiol (2009) 1.18
Alanine-scanning mutagenesis defines a conserved energetic hotspot in the CaValpha1 AID-CaVbeta interaction site that is critical for channel modulation. Structure (2008) 1.17
The retention factor p11 confers an endoplasmic reticulum-localization signal to the potassium channel TASK-1. Traffic (2006) 1.15
Myelin membrane assembly is driven by a phase transition of myelin basic proteins into a cohesive protein meshwork. PLoS Biol (2013) 1.14
Metabolic and thermal stimuli control K(2P)2.1 (TREK-1) through modular sensory and gating domains. EMBO J (2012) 1.14
Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization. EMBO J (2010) 1.13
Functional analysis of Hsp70 inhibitors. PLoS One (2013) 1.13
Ultrathin nucleoporin phenylalanine-glycine repeat films and their interaction with nuclear transport receptors. EMBO Rep (2010) 1.10
Structures of Get3, Get4, and Get5 provide new models for TA membrane protein targeting. Structure (2010) 1.10
Influence of GrpE on DnaK-substrate interactions. J Biol Chem (2004) 1.10
Scavenging of 14-3-3 proteins reveals their involvement in the cell-surface transport of ATP-sensitive K+ channels. J Cell Sci (2006) 1.08
Disruption of the IS6-AID linker affects voltage-gated calcium channel inactivation and facilitation. J Gen Physiol (2009) 1.08
Unconventional protein secretion: membrane translocation of FGF-2 does not require protein unfolding. J Cell Sci (2004) 1.08
A glutamate switch controls voltage-sensitive phosphatase function. Nat Struct Mol Biol (2012) 1.06
Structural basis for the differential effects of CaBP1 and calmodulin on Ca(V)1.2 calcium-dependent inactivation. Structure (2010) 1.06
CHIP participates in protein triage decisions by preferentially ubiquitinating Hsp70-bound substrates. FEBS J (2010) 1.06
Dynamics of the regulation of Hsp90 by the co-chaperone Sti1. EMBO J (2012) 1.05
A green fluorescent protein screen for identification of well-expressed membrane proteins from a cohort of extremophilic organisms. Protein Sci (2009) 1.04
Functional characterization of the atypical Hsp70 subunit of yeast ribosome-associated complex. J Biol Chem (2007) 1.03
2007 annual progress report synopsis of the Center for Structures of Membrane Proteins. J Struct Funct Genomics (2009) 1.03
Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity. Proc Natl Acad Sci U S A (2012) 1.02
The chaperone network connected to human ribosome-associated complex. Mol Cell Biol (2011) 1.02
Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC). Proc Natl Acad Sci U S A (2013) 1.02
Insights into the conformational dynamics of the E3 ubiquitin ligase CHIP in complex with chaperones and E2 enzymes. Biochemistry (2010) 1.02
Membrane proteins as 14-3-3 clients in functional regulation and intracellular transport. Physiology (Bethesda) (2011) 1.00
Novel cargo-binding site in the beta and delta subunits of coatomer. J Cell Biol (2007) 1.00
The yeast CLC protein counteracts vesicular acidification during iron starvation. J Cell Sci (2010) 0.99
Selection of inhibitor-resistant viral potassium channels identifies a selectivity filter site that affects barium and amantadine block. PLoS One (2009) 0.97
Direct transport across the plasma membrane of mammalian cells of Leishmania HASPB as revealed by a CHO export mutant. J Cell Sci (2005) 0.97
Transmembrane domain length of viral K+ channels is a signal for mitochondria targeting. Proc Natl Acad Sci U S A (2008) 0.96
Analysis of subsecond protein dynamics by amide hydrogen exchange and mass spectrometry using a quenched-flow setup. Protein Sci (2005) 0.96
A high-throughput functional screen identifies small molecule regulators of temperature- and mechano-sensitive K2P channels. ACS Chem Biol (2013) 0.95
Get3 is a holdase chaperone and moves to deposition sites for aggregated proteins when membrane targeting is blocked. J Cell Sci (2012) 0.95
Dynamic enzyme docking to the ribosome coordinates N-terminal processing with polypeptide folding. Nat Struct Mol Biol (2013) 0.95
Modeling Hsp70-mediated protein folding. Biophys J (2006) 0.95
An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly. J Biol Chem (2014) 0.93
Mechanisms of protein folding: molecular chaperones and their application in biotechnology. Chembiochem (2002) 0.93
The association of BAG6 with SGTA and tail-anchored proteins. PLoS One (2013) 0.91
Trafficking of potassium channels. Curr Opin Neurobiol (2005) 0.91
Crystal structure of a trimeric form of the K(V)7.1 (KCNQ1) A-domain tail coiled-coil reveals structural plasticity and context dependent changes in a putative coiled-coil trimerization motif. Protein Sci (2009) 0.90
From a ratchet mechanism to random fluctuations evolution of Hsp90's mechanochemical cycle. J Mol Biol (2012) 0.90
Yeast Ist2 recruits the endoplasmic reticulum to the plasma membrane and creates a ribosome-free membrane microcompartment. PLoS One (2012) 0.90
Structure of a Ca(2+)/CaM:Kv7.4 (KCNQ4) B-helix complex provides insight into M current modulation. J Mol Biol (2012) 0.89
Nanoscale protein assemblies from a circular permutant of the tobacco mosaic virus. Nano Lett (2010) 0.89
Lipids trigger a conformational switch that regulates signal recognition particle (SRP)-mediated protein targeting. J Biol Chem (2011) 0.89
Rapid desalting of protein samples for on-line microflow electrospray ionization mass spectrometry. Anal Biochem (2004) 0.89
Tuning the electrical properties of the heart by differential trafficking of KATP ion channel complexes. J Cell Sci (2014) 0.89
Patch-clamp characterization of the MscS-like mechanosensitive channel from Silicibacter pomeroyi. Biophys J (2013) 0.89