Published in PLoS Biol on June 04, 2013
Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue. Cell (2014) 1.56
Phase transitions and size scaling of membrane-less organelles. J Cell Biol (2013) 1.46
Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules. Elife (2015) 1.34
Assemblages: functional units formed by cellular phase separation. J Cell Biol (2014) 1.30
A unified cell biological perspective on axon-myelin injury. J Cell Biol (2014) 0.98
What macromolecular crowding can do to a protein. Int J Mol Sci (2014) 0.96
Axon-glia interaction and membrane traffic in myelin formation. Front Cell Neurosci (2014) 0.90
Multiple sclerosis autoantigen myelin basic protein escapes control by ubiquitination during proteasomal degradation. J Biol Chem (2014) 0.88
Making myelin basic protein -from mRNA transport to localized translation. Front Cell Neurosci (2013) 0.87
Atomic resolution view into the structure-function relationships of the human myelin peripheral membrane protein P2. Acta Crystallogr D Biol Crystallogr (2013) 0.85
Lipid domains control myelin basic protein adsorption and membrane interactions between model myelin lipid bilayers. Proc Natl Acad Sci U S A (2014) 0.84
Remodeling myelination: implications for mechanisms of neural plasticity. Nat Neurosci (2016) 0.84
Widespread expression of erythropoietin receptor in brain and its induction by injury. Mol Med (2015) 0.83
Probing protein disorder and complexity at single-molecule resolution. Semin Cell Dev Biol (2014) 0.82
Myelin basic protein induces neuron-specific toxicity by directly damaging the neuronal plasma membrane. PLoS One (2014) 0.81
How do disordered regions achieve comparable functions to structured domains? Protein Sci (2015) 0.81
Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin. Cell Rep (2017) 0.79
Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases. Cell Rep (2016) 0.79
The biology of boundary conditions: cellular reconstitution in one, two, and three dimensions. Curr Opin Cell Biol (2013) 0.77
Dynamics of the Peripheral Membrane Protein P2 from Human Myelin Measured by Neutron Scattering--A Comparison between Wild-Type Protein and a Hinge Mutant. PLoS One (2015) 0.77
Oligodendrocytes in a Nutshell. Front Cell Neurosci (2015) 0.77
Compartmentalization and Functionality of Nuclear Disorder: Intrinsic Disorder and Protein-Protein Interactions in Intra-Nuclear Compartments. Int J Mol Sci (2015) 0.77
Interaction of myelin basic protein with cytoskeletal and signaling proteins in cultured primary oligodendrocytes and N19 oligodendroglial cells. BMC Res Notes (2014) 0.77
Neutron scattering from myelin revisited: bilayer asymmetry and water-exchange kinetics. Acta Crystallogr D Biol Crystallogr (2014) 0.76
Interplay between exercise and dietary fat modulates myelinogenesis in the central nervous system. Biochim Biophys Acta (2016) 0.76
Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model. Nat Commun (2016) 0.75
Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy. Biophys J (2016) 0.75
Oligodendroglial membrane dynamics in relation to myelin biogenesis. Cell Mol Life Sci (2016) 0.75
Ion mobility-enhanced MS(E)-based label-free analysis reveals effects of low-dose radiation post contextual fear conditioning training on the mouse hippocampal proteome. J Proteomics (2016) 0.75
The transcriptome of mouse central nervous system myelin. Sci Rep (2016) 0.75
Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2. Sci Rep (2017) 0.75
On the origin of non-membrane-bound organelles, and their physiological function. J Theor Biol (2017) 0.75
Protein misfolding, functional amyloid, and human disease. Annu Rev Biochem (2006) 22.87
Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels. Cell (2012) 6.83
Germline P granules are liquid droplets that localize by controlled dissolution/condensation. Science (2009) 5.55
Membrane phosphatidylserine regulates surface charge and protein localization. Science (2008) 5.37
The mystery and magic of glia: a perspective on their roles in health and disease. Neuron (2008) 5.32
Functional amyloid--from bacteria to humans. Trends Biochem Sci (2007) 4.50
FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties. Science (2006) 4.34
An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways. Nat Methods (2005) 4.23
The local differentiation of myelinated axons at nodes of Ranvier. Nat Rev Neurosci (2003) 4.14
Microdomains of GPI-anchored proteins in living cells revealed by crosslinking. Nature (1998) 4.08
Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions. Cell (2011) 3.98
Intrinsically disordered proteins in human diseases: introducing the D2 concept. Annu Rev Biophys (2008) 3.98
Mechanisms of axon ensheathment and myelin growth. Nat Rev Neurosci (2005) 3.85
Functional amyloids as natural storage of peptide hormones in pituitary secretory granules. Science (2009) 3.78
Phase transitions in the assembly of multivalent signalling proteins. Nature (2012) 3.49
Control of local protein synthesis and initial events in myelination by action potentials. Science (2011) 3.35
Regulation of oligodendrocyte differentiation and myelination. Science (2010) 2.98
Getting RNA and protein in phase. Cell (2012) 2.48
Myelin basic protein: a multifunctional protein. Cell Mol Life Sci (2006) 2.23
Characterization of cloned cDNA representing rat myelin basic protein: absence of expression in brain of shiverer mutant mice. Cell (1983) 2.02
A culture system to study oligodendrocyte myelination processes using engineered nanofibers. Nat Methods (2012) 1.70
Cell biology. Beyond oil and water--phase transitions in cells. Science (2012) 1.67
Myelin basic protein-diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosis. Micron (2004) 1.62
Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J Neurosci (2007) 1.58
The permeability of reconstituted nuclear pores provides direct evidence for the selective phase model. Cell (2012) 1.50
Neuron to glia signaling triggers myelin membrane exocytosis from endosomal storage sites. J Cell Biol (2006) 1.49
Molecular domains of myelinated axons in the peripheral nervous system. Glia (2008) 1.44
Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2-dependent RNA granules. J Cell Biol (2008) 1.44
Structural polymorphism and multifunctionality of myelin basic protein. Biochemistry (2009) 1.39
P granules extend the nuclear pore complex environment in the C. elegans germ line. J Cell Biol (2011) 1.34
A size barrier limits protein diffusion at the cell surface to generate lipid-rich myelin-membrane sheets. Dev Cell (2011) 1.28
Amyloid-like interactions within nucleoporin FG hydrogels. Proc Natl Acad Sci U S A (2010) 1.26
Real-time study of E-cadherin and membrane dynamics in living animals: implications for disease modeling and drug development. Cancer Res (2009) 1.25
Central nervous system myelin: structure, synthesis and assembly. Trends Cell Biol (2011) 1.18
Imaging central nervous system myelin by positron emission tomography in multiple sclerosis using [methyl-¹¹C]-2-(4'-methylaminophenyl)- 6-hydroxybenzothiazole. Ann Neurol (2011) 1.18
Translation of myelin basic protein mRNA in oligodendrocytes is regulated by integrin activation and hnRNP-K. J Cell Biol (2011) 1.14
A comparison of amyloid fibrillogenesis using the novel fluorescent compound K114. J Neurochem (2003) 1.13
Force measurements on myelin basic protein adsorbed to mica and lipid bilayer surfaces done with the atomic force microscope. Biophys J (1999) 1.13
Long-term rescue of a lethal inherited disease by adeno-associated virus-mediated gene transfer in a mouse model of molybdenum-cofactor deficiency. Am J Hum Genet (2006) 1.12
Oligodendrocyte-specific gene expression in mouse brain: use of a myelin-forming cell type-specific promoter in an adeno-associated virus. J Neurosci Res (1999) 1.11
Prediction of amyloid aggregation in vivo. EMBO Rep (2011) 1.11
Ultrathin nucleoporin phenylalanine-glycine repeat films and their interaction with nuclear transport receptors. EMBO Rep (2010) 1.10
Beyond stereospecificity: liquids and mesoscale organization of cytoplasm. Dev Cell (2011) 1.08
Fluorescence recovery after photobleaching studies of lipid rafts. Methods Mol Biol (2007) 1.07
Lateral assembly of the immunoglobulin protein SynCAM 1 controls its adhesive function and instructs synapse formation. EMBO J (2011) 1.06
Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria. Nat Chem Biol (2012) 1.05
Temperature dependence of formation of a supported phospholipid bilayer from vesicles on SiO2. Phys Rev E Stat Nonlin Soft Matter Phys (2002) 1.03
Membrane surface charge dictates the structure and function of the epithelial Na+/H+ exchanger. EMBO J (2011) 0.99
Phosphatidylinositol 4,5-bisphosphate-dependent interaction of myelin basic protein with the plasma membrane in oligodendroglial cells and its rapid perturbation by elevated calcium. J Neurosci (2009) 0.97
Increasing internodal distance in myelinated nerves accelerates nerve conduction to a flat maximum. Curr Biol (2012) 0.95
Optimization of the hydrochloric acid concentration used for trifluoroacetate removal from synthetic peptides. J Pept Sci (2007) 0.94
Differential lipid packing abilities and dynamics in giant unilamellar vesicles composed of short-chain saturated glycerol-phospholipids, sphingomyelin and cholesterol. Chem Phys Lipids (2005) 0.92
Stability of lipid domains. FEBS Lett (2009) 0.88
Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science (2008) 9.42
FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties. Science (2006) 4.34
ARAMEMNON, a novel database for Arabidopsis integral membrane proteins. Plant Physiol (2003) 4.15
A saturated FG-repeat hydrogel can reproduce the permeability properties of nuclear pore complexes. Cell (2007) 3.90
Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease. Acta Neuropathol (2002) 3.48
Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein. Proc Natl Acad Sci U S A (2005) 3.48
The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion. EMBO J (2002) 3.34
A selective block of nuclear actin export stabilizes the giant nuclei of Xenopus oocytes. Nat Cell Biol (2006) 3.09
Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. EMBO J (2002) 3.03
Structure of the human voltage-dependent anion channel. Proc Natl Acad Sci U S A (2008) 2.69
Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol (2013) 2.61
Transcription analysis of arabidopsis membrane transporters and hormone pathways during developmental and induced leaf senescence. Plant Physiol (2006) 2.57
Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C. J Cell Biol (2010) 2.52
VDAC, a multi-functional mitochondrial protein regulating cell life and death. Mol Aspects Med (2010) 2.36
Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis. J Cell Sci (2011) 2.25
Mars -- robust automatic backbone assignment of proteins. J Biomol NMR (2004) 2.22
Characterisation of the passive permeability barrier of nuclear pore complexes. EMBO J (2009) 2.21
Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. EMBO J (2002) 2.17
NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat Struct Mol Biol (2010) 2.12
β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons. Ann Neurol (2013) 2.10
Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models. EMBO J (2009) 2.09
Crystal structure of the nuclear export receptor CRM1 in complex with Snurportin1 and RanGTP. Science (2009) 2.08
NMR structural and kinetic characterization of a homeodomain diffusing and hopping on nonspecific DNA. Proc Natl Acad Sci U S A (2006) 2.05
Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein. J Biol Chem (2008) 1.94
Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes. EMBO J (2003) 1.89
Nuclear import of HIV-1 intracellular reverse transcription complexes is mediated by importin 7. EMBO J (2003) 1.80
Defining long-range order and local disorder in native alpha-synuclein using residual dipolar couplings. J Am Chem Soc (2005) 1.75
NDC1: a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes. J Cell Biol (2006) 1.67
Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting. Science (2008) 1.67
A ligand-induced switch in the periplasmic domain of sensor histidine kinase CitA. J Mol Biol (2008) 1.61
Structural polymorphism of 441-residue tau at single residue resolution. PLoS Biol (2009) 1.61
Flotillin-dependent clustering of the amyloid precursor protein regulates its endocytosis and amyloidogenic processing in neurons. J Neurosci (2008) 1.59
Arabidopsis STN7 kinase provides a link between short- and long-term photosynthetic acclimation. Plant Cell (2009) 1.58
The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J (2013) 1.58
Phosphorylation of synucleins by members of the Polo-like kinase family. J Biol Chem (2009) 1.57
Sites of tau important for aggregation populate {beta}-structure and bind to microtubules and polyanions. J Biol Chem (2005) 1.54
Dissociation of amyloid fibrils of alpha-synuclein in supercooled water. Angew Chem Int Ed Engl (2008) 1.51
The permeability of reconstituted nuclear pores provides direct evidence for the selective phase model. Cell (2012) 1.50
Structural characterization of copper(II) binding to alpha-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease. Proc Natl Acad Sci U S A (2005) 1.50
Neuron to glia signaling triggers myelin membrane exocytosis from endosomal storage sites. J Cell Biol (2006) 1.49
Highly populated turn conformations in natively unfolded tau protein identified from residual dipolar couplings and molecular simulation. J Am Chem Soc (2007) 1.49
The NMR structure of the sensory domain of the membranous two-component fumarate sensor (histidine protein kinase) DcuS of Escherichia coli. J Biol Chem (2003) 1.48
Mechanical properties of giant liposomes compressed between two parallel plates: impact of artificial actin shells. Langmuir (2013) 1.46
Asc1p, a WD40-domain containing adaptor protein, is required for the interaction of the RNA-binding protein Scp160p with polysomes. Biochem J (2004) 1.46
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions. J Neurosci (2010) 1.46
NMR characterization of long-range order in intrinsically disordered proteins. J Am Chem Soc (2010) 1.43
Ran-dependent nuclear export mediators: a structural perspective. EMBO J (2011) 1.42
The Arabidopsis plastidic glucose 6-phosphate/phosphate translocator GPT1 is essential for pollen maturation and embryo sac development. Plant Cell (2005) 1.41
NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation. EMBO J (2004) 1.41
Phase selection of calcium carbonate through the chirality of adsorbed amino acids. Angew Chem Int Ed Engl (2007) 1.40
NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules. Mol Biol Cell (2006) 1.37
Structural properties of pore-forming oligomers of alpha-synuclein. J Am Chem Soc (2009) 1.36
Interorganellar communication. Curr Opin Plant Biol (2007) 1.36
Control of oligodendroglial cell number by the miR-17-92 cluster. Development (2010) 1.35
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathol (2013) 1.34
Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings. Structure (2009) 1.33
Exosomes: vesicular carriers for intercellular communication in neurodegenerative disorders. Cell Tissue Res (2012) 1.31
Familial mutants of alpha-synuclein with increased neurotoxicity have a destabilized conformation. J Biol Chem (2005) 1.30
Inhibition of myelin membrane sheath formation by oligodendrocyte-derived exosome-like vesicles. J Biol Chem (2010) 1.29
Structural and functional characterization of the two phosphoinositide binding sites of PROPPINs, a β-propeller protein family. Proc Natl Acad Sci U S A (2012) 1.29
Structure of the mitochondrial translocator protein in complex with a diagnostic ligand. Science (2014) 1.29
Interaction of alpha-synuclein with divalent metal ions reveals key differences: a link between structure, binding specificity and fibrillation enhancement. J Am Chem Soc (2006) 1.28
A size barrier limits protein diffusion at the cell surface to generate lipid-rich myelin-membrane sheets. Dev Cell (2011) 1.28
Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin. FASEB J (2009) 1.28
Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization. J Biol Chem (2005) 1.27
Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes. EMBO J (2012) 1.27
Amyloid-like interactions within nucleoporin FG hydrogels. Proc Natl Acad Sci U S A (2010) 1.26
Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression of Cnp1. Glia (2009) 1.25
The "jaws" of the tau-microtubule interaction. J Biol Chem (2007) 1.25
The histone H2B monoubiquitination regulatory pathway is required for differentiation of multipotent stem cells. Mol Cell (2012) 1.25
Mutants for photosystem I subunit D of Arabidopsis thaliana: effects on photosynthesis, photosystem I stability and expression of nuclear genes for chloroplast functions. Plant J (2004) 1.23
FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties. EMBO J (2009) 1.22
Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. J Cell Biol (2009) 1.22
Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation. J Mol Biol (2007) 1.21
Structural basis for the cytoskeletal association of Bcr-Abl/c-Abl. Mol Cell (2005) 1.21
Nuclear pore complex assembly and maintenance in POM121- and gp210-deficient cells. J Cell Biol (2006) 1.20
Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. J Am Chem Soc (2012) 1.19
Structural characterization of alpha-synuclein in an aggregation prone state. Protein Sci (2009) 1.18
Central nervous system myelin: structure, synthesis and assembly. Trends Cell Biol (2011) 1.18
Inducible expression of coding and inhibitory RNAs from retargetable genomic loci. Nucleic Acids Res (2009) 1.17
Exportin 7 defines a novel general nuclear export pathway. EMBO J (2004) 1.17
Site-specific interactions of Cu(II) with alpha and beta-synuclein: bridging the molecular gap between metal binding and aggregation. J Am Chem Soc (2008) 1.15
Sumoylation inhibits alpha-synuclein aggregation and toxicity. J Cell Biol (2011) 1.13
Functional dynamics in the voltage-dependent anion channel. Proc Natl Acad Sci U S A (2010) 1.13
Exosome secretion ameliorates lysosomal storage of cholesterol in Niemann-Pick type C disease. J Biol Chem (2010) 1.12
Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules. Biochemistry (2009) 1.12
Cell visco-elasticity measured with AFM and optical trapping at sub-micrometer deformations. PLoS One (2012) 1.12