Yeast Ist2 recruits the endoplasmic reticulum to the plasma membrane and creates a ribosome-free membrane microcompartment.

PubWeight™: 0.90‹?›

🔗 View Article (PMC 3392263)

Published in PLoS One on July 09, 2012

Authors

Wendelin Wolf1, Annett Kilic, Bianca Schrul, Holger Lorenz, Blanche Schwappach, Matthias Seedorf

Author Affiliations

1: Zentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH-Allianz, Heidelberg, Germany.

Articles citing this

ER-PM connections: sites of information transfer and inter-organelle communication. Curr Opin Cell Biol (2013) 1.36

Untangling the web: mechanisms underlying ER network formation. Biochim Biophys Acta (2013) 1.23

Identification of a lipid scrambling domain in ANO6/TMEM16F. Elife (2015) 1.12

Barriers to the free diffusion of proteins and lipids in the plasma membrane. J Cell Biol (2015) 0.97

A Pore Idea: the ion conduction pathway of TMEM16/ANO proteins is composed partly of lipid. Pflugers Arch (2016) 0.92

Mammalian phosphatidylinositol 4-kinases as modulators of membrane trafficking and lipid signaling networks. Prog Lipid Res (2013) 0.89

Subdued, a TMEM16 family Ca²⁺-activated Cl⁻channel in Drosophila melanogaster with an unexpected role in host defense. Elife (2013) 0.88

The ER/PM microdomain, PI(4,5)P₂ and the regulation of STIM1-Orai1 channel function. Cell Calcium (2015) 0.83

Oligomerization and Ca2+/calmodulin control binding of the ER Ca2+-sensors STIM1 and STIM2 to plasma membrane lipids. Biosci Rep (2013) 0.82

Septins and Generation of Asymmetries in Fungal Cells. Annu Rev Microbiol (2015) 0.81

Anoctamins support calcium-dependent chloride secretion by facilitating calcium signaling in adult mouse intestine. Pflugers Arch (2014) 0.80

TMEM110 regulates the maintenance and remodeling of mammalian ER-plasma membrane junctions competent for STIM-ORAI signaling. Proc Natl Acad Sci U S A (2015) 0.80

Modulating Ca(2+) signals: a common theme for TMEM16, Ist2, and TMC. Pflugers Arch (2015) 0.79

Anoctamins/TMEM16 Proteins: Chloride Channels Flirting with Lipids and Extracellular Vesicles. Annu Rev Physiol (2016) 0.78

Orai1 and STIM1 in ER/PM junctions: roles in pancreatic cell function and dysfunction. Am J Physiol Cell Physiol (2016) 0.78

Forging the ring: from fungal septins' divergent roles in morphology, septation and virulence to factors contributing to their assembly into higher order structures. Microbiology (2016) 0.76

A protein complex containing Epo1p anchors the cortical endoplasmic reticulum to the yeast bud tip. J Cell Biol (2014) 0.75

Ist2 in the yeast cortical endoplasmic reticulum promotes trafficking of the amino acid transporter Bap2 to the plasma membrane. PLoS One (2014) 0.75

Articles cited by this

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics (1989) 105.30

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science (1999) 36.25

Lipid rafts and signal transduction. Nat Rev Mol Cell Biol (2000) 25.87

Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast (1998) 23.00

A guided tour into subcellular colocalization analysis in light microscopy. J Microsc (2006) 16.73

A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes. Yeast (2004) 9.02

TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. Science (2008) 8.74

A class of membrane proteins shaping the tubular endoplasmic reticulum. Cell (2006) 8.53

TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature (2008) 8.40

Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell (2008) 7.79

Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier. Science (2000) 4.95

The yeast secretory pathway is perturbed by mutations in PMR1, a member of a Ca2+ ATPase family. Cell (1989) 4.19

Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae. J Cell Biol (2000) 3.73

Calcium-dependent phospholipid scrambling by TMEM16F. Nature (2010) 3.63

Mechanisms determining the morphology of the peripheral ER. Cell (2010) 3.35

Eisosomes mark static sites of endocytosis. Nature (2006) 2.95

Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone. Mol Cell Biol (1992) 2.80

Anoctamin/TMEM16 family members are Ca2+-activated Cl- channels. J Physiol (2008) 2.66

Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.54

In vivo glucose activation of the yeast plasma membrane ATPase. FEBS Lett (1983) 2.49

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response. J Cell Biol (2009) 2.35

Visualization of protein compartmentation within the plasma membrane of living yeast cells. Mol Biol Cell (2003) 2.22

A 3D analysis of yeast ER structure reveals how ER domains are organized by membrane curvature. J Cell Biol (2011) 2.21

A subfraction of the yeast endoplasmic reticulum associates with the plasma membrane and has a high capacity to synthesize lipids. Eur J Biochem (2001) 2.07

Intracellular sequestration of sodium by a novel Na+/H+ exchanger in yeast is enhanced by mutations in the plasma membrane H+-ATPase. Insights into mechanisms of sodium tolerance. J Biol Chem (1997) 1.98

Membrane potential governs lateral segregation of plasma membrane proteins and lipids in yeast. EMBO J (2006) 1.83

Plasma membrane microdomains regulate turnover of transport proteins in yeast. J Cell Biol (2008) 1.77

From the Cover: STIM1-induced precortical and cortical subdomains of the endoplasmic reticulum. Proc Natl Acad Sci U S A (2009) 1.71

Phosphatidic acid is a pH biosensor that links membrane biogenesis to metabolism. Science (2010) 1.64

Distribution of Can1p into stable domains reflects lateral protein segregation within the plasma membrane of living S. cerevisiae cells. J Cell Sci (2004) 1.61

The Sur7p family defines novel cortical domains in Saccharomyces cerevisiae, affects sphingolipid metabolism, and is involved in sporulation. Mol Cell Biol (2002) 1.54

Scp160p, an RNA-binding, polysome-associated protein, localizes to the endoplasmic reticulum of Saccharomyces cerevisiae in a microtubule-dependent manner. J Biol Chem (2001) 1.54

Furrow-like invaginations of the yeast plasma membrane correspond to membrane compartment of Can1. J Cell Sci (2009) 1.51

Alkali metal cation transport and homeostasis in yeasts. Microbiol Mol Biol Rev (2010) 1.46

Regulation of yeast H(+)-ATPase by protein kinases belonging to a family dedicated to activation of plasma membrane transporters. Mol Cell Biol (2000) 1.41

Membrane potential defect in hygromycin B-resistant pma1 mutants of Saccharomyces cerevisiae. J Biol Chem (1988) 1.38

SEC18/NSF-independent, protein-sorting pathway from the yeast cortical ER to the plasma membrane. J Cell Biol (2005) 1.33

Mutagenic study of the structure, function and biogenesis of the yeast plasma membrane H(+)-ATPase. Biochim Biophys Acta (2000) 1.32

A cryosectioning procedure for the ultrastructural analysis and the immunogold labelling of yeast Saccharomyces cerevisiae. Traffic (2008) 1.30

Depletion of calcium in the synaptic cleft of a calyx-type synapse in the rat brainstem. J Physiol (1999) 1.23

A novel transport pathway for a yeast plasma membrane protein encoded by a localized mRNA. Curr Biol (2004) 1.19

Regulation of plasma membrane H(+)-ATPase in fungi and plants. Biochim Biophys Acta (2000) 1.19

Ion tolerance of Saccharomyces cerevisiae lacking the Ca2+/CaM-dependent phosphatase (calcineurin) is improved by mutations in URE2 or PMA1. Genetics (1998) 1.18

A conserved, lipid-mediated sorting mechanism of yeast Ist2 and mammalian STIM proteins to the peripheral ER. Traffic (2009) 1.16

The lateral compartmentation of the yeast plasma membrane. Yeast (2010) 1.15

Reassessment of the role of plasma membrane domains in the regulation of vesicular traffic in yeast. J Cell Sci (2011) 1.13

Phosphorylation of yeast plasma membrane H+-ATPase by casein kinase I. J Biol Chem (1996) 1.06

Induction of cortical endoplasmic reticulum by dimerization of a coatomer-binding peptide anchored to endoplasmic reticulum membranes. Proc Natl Acad Sci U S A (2010) 1.04

The yeast CLC protein counteracts vesicular acidification during iron starvation. J Cell Sci (2010) 0.99

Btn2, a Hook1 ortholog and potential Batten disease-related protein, mediates late endosome-Golgi protein sorting in yeast. Mol Cell Biol (2006) 0.99

Interaction among Btn1p, Btn2p, and Ist2p reveals potential interplay among the vacuole, amino acid levels, and ion homeostasis in the yeast Saccharomyces cerevisiae. Eukaryot Cell (2005) 0.98

Characterization of a protein serine kinase from yeast plasma membrane. J Biol Chem (1988) 0.97

Distribution of cortical endoplasmic reticulum determines positioning of endocytic events in yeast plasma membrane. PLoS One (2012) 0.95

Interactions of the proteins of neuronal ceroid lipofuscinosis: clues to function. Cell Mol Life Sci (2010) 0.93

Mechanism of polyamine tolerance in yeast: novel regulators and insights. Cell Mol Life Sci (2005) 0.92

Binding of plasma membrane lipids recruits the yeast integral membrane protein Ist2 to the cortical ER. Traffic (2009) 0.92

A signal comprising a basic cluster and an amphipathic alpha-helix interacts with lipids and is required for the transport of Ist2 to the yeast cortical ER. J Cell Sci (2009) 0.88

Na+-dependent amino acid transport is a major factor determining the rate of (Na+,K+)-ATPase mediated cation transport in intact HeLa cells. J Cell Physiol (1986) 0.85

Chloride homeostasis in Saccharomyces cerevisiae: high affinity influx, V-ATPase-dependent sequestration, and identification of a candidate Cl- sensor. J Gen Physiol (2008) 0.83

A complex peptide-sorting signal, but no mRNA signal, is required for the Sec-independent transport of Ist2 from the yeast ER to the plasma membrane. FEBS Lett (2007) 0.80

Articles by these authors

Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science (2009) 4.58

The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell (2008) 3.51

Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. EMBO J (2002) 3.03

The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair. Cell Stem Cell (2009) 2.11

Distinct targeting pathways for the membrane insertion of tail-anchored (TA) proteins. J Cell Sci (2008) 2.11

Hide and run. Arginine-based endoplasmic-reticulum-sorting motifs in the assembly of heteromultimeric membrane proteins. EMBO Rep (2005) 2.04

The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. J Neurochem (2011) 1.93

The DEAD-box RNA helicase Dbp5 functions in translation termination. Science (2007) 1.83

14-3-3 dimers probe the assembly status of multimeric membrane proteins. Curr Biol (2003) 1.79

Unconventional mechanisms of protein transport to the cell surface of eukaryotic cells. Annu Rev Cell Dev Biol (2008) 1.72

Bat3 promotes the membrane integration of tail-anchored proteins. J Cell Sci (2010) 1.71

Biogenesis of tail-anchored proteins: the beginning for the end? J Cell Sci (2009) 1.64

Asc1p, a WD40-domain containing adaptor protein, is required for the interaction of the RNA-binding protein Scp160p with polysomes. Biochem J (2004) 1.46

Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor. Mol Cell Biol (2004) 1.44

Multiple glutathione disulfide removal pathways mediate cytosolic redox homeostasis. Nat Chem Biol (2012) 1.42

SEC18/NSF-independent, protein-sorting pathway from the yeast cortical ER to the plasma membrane. J Cell Biol (2005) 1.33

WRB is the receptor for TRC40/Asna1-mediated insertion of tail-anchored proteins into the ER membrane. J Cell Sci (2011) 1.30

14-3-3 proteins in membrane protein transport. Biol Chem (2006) 1.25

The secretory membrane system in the Drosophila syncytial blastoderm embryo exists as functionally compartmentalized units around individual nuclei. J Cell Biol (2006) 1.21

The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol. J Biol Chem (2005) 1.19

A novel transport pathway for a yeast plasma membrane protein encoded by a localized mRNA. Curr Biol (2004) 1.19

Biosynthetic FGF-2 is targeted to non-lipid raft microdomains following translocation to the extracellular surface of CHO cells. J Cell Sci (2002) 1.19

Intracellular traffic of the K+ channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins. J Physiol (2009) 1.18

The SESA network links duplication of the yeast centrosome with the protein translation machinery. Genes Dev (2009) 1.18

A conserved, lipid-mediated sorting mechanism of yeast Ist2 and mammalian STIM proteins to the peripheral ER. Traffic (2009) 1.16

The retention factor p11 confers an endoplasmic reticulum-localization signal to the potassium channel TASK-1. Traffic (2006) 1.15

Structures of Get3, Get4, and Get5 provide new models for TA membrane protein targeting. Structure (2010) 1.10

Scavenging of 14-3-3 proteins reveals their involvement in the cell-surface transport of ATP-sensitive K+ channels. J Cell Sci (2006) 1.08

Unconventional protein secretion: membrane translocation of FGF-2 does not require protein unfolding. J Cell Sci (2004) 1.08

Loss of glycosylation associated with the T183A mutation in human prion disease. Acta Neuropathol (2004) 1.06

Segregation of yeast nuclear pores. Nature (2010) 1.01

Membrane proteins as 14-3-3 clients in functional regulation and intracellular transport. Physiology (Bethesda) (2011) 1.00

Novel cargo-binding site in the beta and delta subunits of coatomer. J Cell Biol (2007) 1.00

The yeast CLC protein counteracts vesicular acidification during iron starvation. J Cell Sci (2010) 0.99

Direct transport across the plasma membrane of mammalian cells of Leishmania HASPB as revealed by a CHO export mutant. J Cell Sci (2005) 0.97

The centriolar satellite protein SSX2IP promotes centrosome maturation. J Cell Biol (2013) 0.96

Seg1 controls eisosome assembly and shape. J Cell Biol (2012) 0.95

Get3 is a holdase chaperone and moves to deposition sites for aggregated proteins when membrane targeting is blocked. J Cell Sci (2012) 0.95

Binding of plasma membrane lipids recruits the yeast integral membrane protein Ist2 to the cortical ER. Traffic (2009) 0.92

The association of BAG6 with SGTA and tail-anchored proteins. PLoS One (2013) 0.91

Trafficking of potassium channels. Curr Opin Neurobiol (2005) 0.91

A multimeric membrane protein reveals 14-3-3 isoform specificity in forward transport in yeast. Traffic (2006) 0.91

Tuning the electrical properties of the heart by differential trafficking of KATP ion channel complexes. J Cell Sci (2014) 0.89

A signal comprising a basic cluster and an amphipathic alpha-helix interacts with lipids and is required for the transport of Ist2 to the yeast cortical ER. J Cell Sci (2009) 0.88

Involvement of Golgin-160 in cell surface transport of renal ROMK channel: co-expression of Golgin-160 increases ROMK currents. Cell Physiol Biochem (2006) 0.86

Pas de deux in groups of four--the biogenesis of KATP channels. J Mol Cell Cardiol (2005) 0.85

SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression. Nat Cell Biol (2013) 0.84

Determining membrane protein topologies in single cells and high-throughput screening applications. Curr Protoc Cell Biol (2010) 0.83

The yeast CLC chloride channel is proteolytically processed by the furin-like protease Kex2p in the first extracellular loop. FEBS Lett (2005) 0.81

The role of protein-protein interactions in the intracellular traffic of the potassium channels TASK-1 and TASK-3. Pflugers Arch (2015) 0.81

A complex peptide-sorting signal, but no mRNA signal, is required for the Sec-independent transport of Ist2 from the yeast ER to the plasma membrane. FEBS Lett (2007) 0.80

The yeast oligopeptide transporter Opt2 is localized to peroxisomes and affects glutathione redox homeostasis. FEMS Yeast Res (2014) 0.79

From rags to riches - the history of the endoplasmic reticulum. Biochim Biophys Acta (2013) 0.78

Di-arginine signals and the K-rich domain retain the Ca²⁺ sensor STIM1 in the endoplasmic reticulum. Traffic (2012) 0.75

Cell biology. Think vesicular chloride. Science (2010) 0.75

Peroxin-dependent targeting of a lipid-droplet-destined membrane protein to ER subdomains. Nat Cell Biol (2016) 0.75

Erratum: 2D map projections for visualization and quantitative analysis of 3D fluorescence micrographs. Sci Rep (2015) 0.75