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Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. Cell Stem Cell (2013) 2.32

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Three different neutrophil subsets exhibited in mice with different susceptibilities to infection by methicillin-resistant Staphylococcus aureus. Immunity (2004) 2.29

No forward shifting of posterior corneal surface in eyes undergoing LASIK. Ophthalmology (2007) 2.21

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Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1. J Biol Chem (2004) 2.17

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Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains. Neurobiol Dis (2002) 2.14

Axonal alpha-synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease. Brain (2007) 2.10

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Increased binding of peripheral benzodiazepine receptor in Alzheimer's disease measured by positron emission tomography with [11C]DAA1106. Biol Psychiatry (2008) 2.06

The impact of preoperative serum C-reactive protein on the prognosis of patients with hepatocellular carcinoma. Cancer (2005) 2.05

TGFα shedding assay: an accurate and versatile method for detecting GPCR activation. Nat Methods (2012) 2.04

Vitamin E decreases bone mass by stimulating osteoclast fusion. Nat Med (2012) 2.04

Fall prevention using olfactory stimulation with lavender odor in elderly nursing home residents: a randomized controlled trial. J Am Geriatr Soc (2012) 2.03

A protein secretion system linked to bacteroidete gliding motility and pathogenesis. Proc Natl Acad Sci U S A (2009) 2.02

TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation. Acta Neuropathol (2007) 2.01

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Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease. J Neurosci (2004) 1.92

Association studies of multiple candidate genes for Parkinson's disease using single nucleotide polymorphisms. Ann Neurol (2002) 1.87

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers. Alzheimers Dement (2011) 1.87

Voxel-based morphometry to discriminate early Alzheimer's disease from controls. Neurosci Lett (2005) 1.86

Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease. Genes Cells (2005) 1.86

CAG repeat disorder models and human neuropathology: similarities and differences. Acta Neuropathol (2007) 1.86

Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster. Proc Natl Acad Sci U S A (2003) 1.85

Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases. Nat Cell Biol (2007) 1.81

Haploinsufficiency of CSF-1R and clinicopathologic characterization in patients with HDLS. Neurology (2013) 1.81

Hepatitis C virus non-structural proteins in the probable membranous compartment function in viral genome replication. J Biol Chem (2003) 1.77

Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation. Cell Metab (2012) 1.77

The MAP1-LC3 conjugation system is involved in lipid droplet formation. Biochem Biophys Res Commun (2009) 1.77

Potent amyloidogenicity and pathogenicity of Aβ43. Nat Neurosci (2011) 1.76

Population-based door-to-door survey of migraine in Japan: the Daisen study. Headache (2004) 1.73

SCA17 homozygote showing Huntington's disease-like phenotype. Ann Neurol (2004) 1.72

The anti-inflammatory and proresolving mediator resolvin E1 protects mice from bacterial pneumonia and acute lung injury. J Immunol (2009) 1.71

Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions. J Biol Chem (2002) 1.71

Active gamma-secretase complexes contain only one of each component. J Biol Chem (2007) 1.69

Clinico-pathological rescue of a model mouse of Huntington's disease by siRNA. Neurosci Res (2005) 1.68

Equimolar production of amyloid beta-protein and amyloid precursor protein intracellular domain from beta-carboxyl-terminal fragment by gamma-secretase. J Biol Chem (2006) 1.66

Zonisamide improves motor function in Parkinson disease: a randomized, double-blind study. Neurology (2007) 1.65

Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling. Genes Dev (2004) 1.63

Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding. Hum Mol Genet (2008) 1.60

Novel 18F-labeled arylquinoline derivatives for noninvasive imaging of tau pathology in Alzheimer disease. J Nucl Med (2013) 1.58

Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology. Acta Neuropathol (2011) 1.58

DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1. Hum Mol Genet (2006) 1.58

Baculovirus induces an innate immune response and confers protection from lethal influenza virus infection in mice. J Immunol (2003) 1.57

A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans. J Clin Invest (2011) 1.57

Purification, gene cloning, gene expression, and mutants of Dps from the obligate anaerobe Porphyromonas gingivalis. Infect Immun (2003) 1.57

High-risk ovarian cancer based on 126-gene expression signature is uniquely characterized by downregulation of antigen presentation pathway. Clin Cancer Res (2012) 1.56

Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid. J Biol Chem (2006) 1.55

ABCA3 as a lipid transporter in pulmonary surfactant biogenesis. J Biol Chem (2007) 1.54

Severe chronic pancreatitis and severe liver cirrhosis have different frequencies and are independent risk factors in male Japanese alcoholics. J Gastroenterol (2004) 1.53

Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1. J Lipid Res (2006) 1.52

Isolation and characterization of patient-derived, toxic, high mass amyloid beta-protein (Abeta) assembly from Alzheimer disease brains. J Biol Chem (2009) 1.52

Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease. FASEB J (2004) 1.51

A randomized, observer-blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms and activities of daily living in dementia patients. J Clin Psychiatry (2005) 1.51

A novel phosphatidic acid-selective phospholipase A1 that produces lysophosphatidic acid. J Biol Chem (2002) 1.49

Potential link between amyloid beta-protein 42 and C-terminal fragment gamma 49-99 of beta-amyloid precursor protein. J Biol Chem (2003) 1.49

Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer. Lab Invest (2004) 1.49

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Longitudinal evaluation of both morphologic and functional changes in the same individuals with Alzheimer's disease. J Nucl Med (2002) 1.48

Cerebrospinal fluid tau protein and periventricular white matter lesions in patients with mild cognitive impairment: implications for 2 major pathways. Arch Neurol (2004) 1.48

LPA-producing enzyme PA-PLA₁α regulates hair follicle development by modulating EGFR signalling. EMBO J (2011) 1.48

Degeneration of cardiac sympathetic nerve can occur in multiple system atrophy. Acta Neuropathol (2006) 1.47

The prediction of rapid conversion to Alzheimer's disease in mild cognitive impairment using regional cerebral blood flow SPECT. Neuroimage (2005) 1.47

The association between use of mobile phones after lights out and sleep disturbances among Japanese adolescents: a nationwide cross-sectional survey. Sleep (2011) 1.47

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Degeneration of cardiac sympathetic nerve begins in the early disease process of Parkinson's disease. Brain Pathol (2007) 1.44

Identification of a new membrane-associated protein that influences transport/maturation of gingipains and adhesins of Porphyromonas gingivalis. J Biol Chem (2005) 1.44

Global democratic consensus on neuropathological disease criteria. Lancet Neurol (2002) 1.44

Impaired efficacy of cough in patients with Parkinson disease. Chest (2003) 1.44

Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease. Nat Cell Biol (2009) 1.41

CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV. EMBO J (2002) 1.41

Ocular integrity after anterior ciliary sclerotomy and scleral ablation by the Er:YAG laser. J Refract Surg (2005) 1.41

Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with and without dementia. Acta Neuropathol (2008) 1.41

HTT haplotypes contribute to differences in Huntington disease prevalence between Europe and East Asia. Eur J Hum Genet (2011) 1.41