Published in Genes Cells on February 01, 2005
Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics. Neurochem Res (2006) 3.12
What Are the bona fide GSK3 Substrates? Int J Alzheimers Dis (2011) 1.65
Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain. J Cell Biol (2005) 1.59
Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones. Mol Cell Biol (2005) 1.56
An atypical role for collapsin response mediator protein 2 (CRMP-2) in neurotransmitter release via interaction with presynaptic voltage-gated calcium channels. J Biol Chem (2009) 1.51
Semaphorin function in neural plasticity and disease. Curr Opin Neurobiol (2009) 1.48
The CRMP family of proteins and their role in Sema3A signaling. Adv Exp Med Biol (2007) 1.43
Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo. J Biol Chem (2006) 1.33
Sema4D/plexin-B1 activates GSK-3beta through R-Ras GAP activity, inducing growth cone collapse. EMBO Rep (2006) 1.32
Neurotransmitters drive combinatorial multistate postsynaptic density networks. Sci Signal (2009) 1.24
Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase. PLoS One (2007) 1.18
ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease. Front Neurosci (2014) 1.10
Fragile X Mental Retardation Protein is Involved in Protein Synthesis-Dependent Collapse of Growth Cones Induced by Semaphorin-3A. Front Neural Circuits (2009) 1.08
Guidance from above: common cues direct distinct signaling outcomes in vascular and neural patterning. Trends Cell Biol (2009) 1.05
Semaphorin 3A induces CaV2.3 channel-dependent conversion of axons to dendrites. Nat Cell Biol (2011) 1.04
Semaphorins and their receptors in lung cancer. Cancer Lett (2008) 1.02
MicroRNA and messenger RNA profiling reveals new biomarkers and mechanisms for RDX induced neurotoxicity. BMC Genomics (2014) 1.02
Integrative mechanisms of oriented neuronal migration in the developing brain. Annu Rev Cell Dev Biol (2013) 0.99
Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32. J Biol Chem (2009) 0.96
Opening Pandora's jar: a primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders. Future Neurol (2012) 0.95
Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration. J Biol Chem (2009) 0.93
Semaphorin 4D/Plexin-B1 stimulates PTEN activity through R-Ras GTPase-activating protein activity, inducing growth cone collapse in hippocampal neurons. J Biol Chem (2010) 0.93
Involvement of WAVE accumulation in Abeta/APP pathology-dependent tangle modification in Alzheimer's disease. Am J Pathol (2009) 0.93
Fyn promotes phosphorylation of collapsin response mediator protein 1 at tyrosine 504, a novel, isoform-specific regulatory site. J Cell Biochem (2010) 0.92
Emerging roles of collapsin response mediator proteins (CRMPs) as regulators of voltage-gated calcium channels and synaptic transmission. Commun Integr Biol (2010) 0.92
Relative resistance of Cdk5-phosphorylated CRMP2 to dephosphorylation. J Biol Chem (2008) 0.91
Collapsin response mediator proteins (CRMPs) are a new class of microtubule-associated protein (MAP) that selectively interacts with assembled microtubules via a taxol-sensitive binding interaction. J Biol Chem (2011) 0.90
Decision making during interneuron migration in the developing cerebral cortex. Trends Cell Biol (2014) 0.90
GSK3 as a Sensor Determining Cell Fate in the Brain. Front Mol Neurosci (2012) 0.90
TIPsy tour guides: how microtubule plus-end tracking proteins (+TIPs) facilitate axon guidance. Front Cell Neurosci (2015) 0.87
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The emerging role of class-3 semaphorins and their neuropilin receptors in oncology. Onco Targets Ther (2014) 0.86
Control of neuronal ion channel function by glycogen synthase kinase-3: new prospective for an old kinase. Front Mol Neurosci (2012) 0.86
CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon Elongation. Neural Plast (2015) 0.85
Molecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical Development. Front Neurosci (2015) 0.84
GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation. Elife (2014) 0.84
Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders. Mol Neurodegener (2011) 0.83
Dynamic proteomics of nucleus accumbens in response to acute psychological stress in environmentally enriched and isolated rats. PLoS One (2013) 0.83
CRMPs: critical molecules for neurite morphogenesis and neuropsychiatric diseases. Mol Psychiatry (2015) 0.83
The Beta-amyloid protein of Alzheimer's disease: communication breakdown by modifying the neuronal cytoskeleton. Int J Alzheimers Dis (2013) 0.82
Alzheimer disease periventricular white matter lesions exhibit specific proteomic profile alterations. Neurochem Int (2012) 0.81
A cell-penetrating ester of the neural metabolite lanthionine ketimine stimulates autophagy through the mTORC1 pathway: Evidence for a mechanism of action with pharmacological implications for neurodegenerative pathologies. Neurobiol Dis (2015) 0.81
Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3ß and CDK5 following traumatic brain injury. Front Cell Neurosci (2014) 0.81
Collapsin response mediator protein-2 phosphorylation promotes the reversible retraction of oligodendrocyte processes in response to non-lethal oxidative stress. J Neurochem (2012) 0.81
Identification of a dithiol-disulfide switch in collapsin response mediator protein 2 (CRMP2) that is toggled in a model of neuronal differentiation. J Biol Chem (2013) 0.81
Crosstalk between intracellular and extracellular signals regulating interneuron production, migration and integration into the cortex. Front Cell Neurosci (2015) 0.81
Bioinformatic prediction and confirmation of beta-adducin as a novel substrate of glycogen synthase kinase 3. J Biol Chem (2011) 0.81
Targeting of CRMP-2 to the primary cilium is modulated by GSK-3β. PLoS One (2012) 0.80
Identification of a proline-rich inositol polyphosphate 5-phosphatase (PIPP)•collapsin response mediator protein 2 (CRMP2) complex that regulates neurite elongation. J Biol Chem (2011) 0.80
Collapsin response mediator proteins: Potential diagnostic and prognostic biomarkers in cancers (Review). Oncol Lett (2014) 0.80
Cdk5: mediator of neuronal development, death and the response to DNA damage. Mech Ageing Dev (2011) 0.80
Developmentally-Dynamic Murine Brain Proteomes and Phosphoproteomes Revealed by Quantitative Proteomics. Proteomes (2014) 0.80
TAG1 regulates the endocytic trafficking and signaling of the semaphorin3A receptor complex. J Neurosci (2012) 0.80
A Systematic Strategy for Discovering a Therapeutic Drug for Alzheimer's Disease and Its Target Molecule. Front Pharmacol (2017) 0.80
Two PTP receptors mediate CSPG inhibition by convergent and divergent signaling pathways in neurons. Sci Rep (2016) 0.79
Insight into the role of CRMP2 (collapsin response mediator protein 2) in T lymphocyte migration: the particular context of virus infection. Cell Adh Migr (2012) 0.79
Semaphorin 3A signaling through neuropilin-1 is an early trigger for distal axonopathy in the SOD1G93A mouse model of amyotrophic lateral sclerosis. J Neuropathol Exp Neurol (2014) 0.79
Specific binding of lacosamide to collapsin response mediator protein 2 (CRMP2) and direct impairment of its canonical function: implications for the therapeutic potential of lacosamide. Mol Neurobiol (2014) 0.79
Cyclin-dependent kinase 5 is required for normal cerebellar development. Mol Cell Neurosci (2012) 0.79
Phosphorylation and mRNA splicing of collapsin response mediator protein-2 determine inhibition of rho-associated protein kinase (ROCK) II function in carcinoma cell migration and invasion. J Biol Chem (2013) 0.79
At the Fulcrum in Health and Disease: Cdk5 and the Balancing Acts of Neuronal Structure and Physiology. Brain Disord Ther (2012) 0.79
Comprehensive annotation of microRNA expression profiles. BMC Genet (2013) 0.79
Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice. PLoS One (2014) 0.78
The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth. Front Cell Neurosci (2014) 0.78
Soluble alpha-APP (sAPPalpha) regulates CDK5 expression and activity in neurons. PLoS One (2013) 0.78
Axonal degeneration in multiple sclerosis: can we predict and prevent permanent disability? Acta Neuropathol Commun (2014) 0.78
LMTK1 regulates dendritic formation by regulating movement of Rab11A-positive endosomes. Mol Biol Cell (2014) 0.78
Neuronal migration and protein kinases. Front Neurosci (2015) 0.78
Cellular transcripts of chicken brain tissues in response to H5N1 and Newcastle disease virus infection. Virol J (2012) 0.77
Collapsin Response Mediator Protein-2 (CRMP2) is a Plausible Etiological Factor and Potential Therapeutic Target in Alzheimer's Disease: Comparison and Contrast with Microtubule-Associated Protein Tau. J Alzheimers Dis (2016) 0.77
Prolyl Isomerase Pin1 Regulates Axon Guidance by Stabilizing CRMP2A Selectively in Distal Axons. Cell Rep (2015) 0.77
Canonical and Non-canonical Reelin Signaling. Front Cell Neurosci (2016) 0.77
Live imaging of endogenous Collapsin response mediator protein-1 expression at subcellular resolution during zebrafish nervous system development. Gene Expr Patterns (2011) 0.77
Mice lacking collapsin response mediator protein 1 manifest hyperactivity, impaired learning and memory, and impaired prepulse inhibition. Front Behav Neurosci (2013) 0.76
Repulsive axon guidance by Draxin is mediated by protein Kinase B (Akt), glycogen synthase kinase-3β (GSK-3β) and microtubule-associated protein 1B. PLoS One (2015) 0.76
A Tale of the Good and Bad: Remodeling of the Microtubule Network in the Brain by Cdk5. Mol Neurobiol (2016) 0.76
Postnatal alteration of collapsin response mediator protein 4 mRNA expression in the mouse brain. J Anat (2012) 0.76
Divergent functions through alternative splicing: the Drosophila CRMP gene in pyrimidine metabolism, brain, and behavior. Genetics (2012) 0.76
Semaphorins and their Signaling Mechanisms. Methods Mol Biol (2017) 0.76
Phosphorylation of CRMP2 by Cdk5 Regulates Dendritic Spine Development of Cortical Neuron in the Mouse Hippocampus. Neural Plast (2015) 0.75
Regulation of dendritic development by semaphorin 3A through novel intracellular remote signaling. Cell Adh Migr (2016) 0.75
Increased phosphorylation of collapsin response mediator protein-2 at Thr514 correlates with β-amyloid burden and synaptic deficits in Lewy body dementias. Mol Brain (2016) 0.75
Differentially expressed proteins underlying childhood cortical dysplasia with epilepsy identified by iTRAQ proteomic profiling. PLoS One (2017) 0.75
Quantitative Phosphoproteomics Reveals a Role for Collapsin Response Mediator Protein 2 in PDGF-Induced Cell Migration. Sci Rep (2017) 0.75
CRMPs Function in Neurons and Glial Cells: Potential Therapeutic Targets for Neurodegenerative Diseases and CNS Injury. Mol Neurobiol (2016) 0.75
A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications. Nat Biotechnol (2002) 22.05
Cdk5-dependent regulation of glucose-stimulated insulin secretion. Nat Med (2005) 4.31
NovoTTF-100A versus physician's choice chemotherapy in recurrent glioblastoma: a randomised phase III trial of a novel treatment modality. Eur J Cancer (2012) 3.66
An essential role for beta-actin mRNA localization and translation in Ca2+-dependent growth cone guidance. Nat Neurosci (2006) 3.30
A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord. Nat Med (2006) 3.28
Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44. Cell (2005) 2.99
The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos. Nature (2002) 2.75
Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs. J Cell Biol (2007) 2.54
IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism. Science (2005) 2.53
gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment. J Neurosci (2009) 2.49
Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase. J Neurosci (2005) 2.48
Spontaneous network activity visualized by ultrasensitive Ca(2+) indicators, yellow Cameleon-Nano. Nat Methods (2010) 2.47
Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport. J Biol Chem (2002) 2.40
Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand. Nature (2002) 2.30
Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning. Nature (2003) 2.18
Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo. J Neurosci (2011) 2.17
A comparison of urinary albumin-total protein ratio to phase-contrast microscopic examination of urine sediment for differentiating glomerular and nonglomerular bleeding. Am J Kidney Dis (2008) 2.07
The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. J Biol Chem (2001) 1.86
Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell (2003) 1.81
Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion. J Cell Biol (2004) 1.80
A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex. Nat Neurosci (2007) 1.76
Potent amyloidogenicity and pathogenicity of Aβ43. Nat Neurosci (2011) 1.76
Activity-dependent tuning of inhibitory neurotransmission based on GABAAR diffusion dynamics. Neuron (2009) 1.74
Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex. Neuron (2002) 1.71
Active gamma-secretase complexes contain only one of each component. J Biol Chem (2007) 1.69
Equimolar production of amyloid beta-protein and amyloid precursor protein intracellular domain from beta-carboxyl-terminal fragment by gamma-secretase. J Biol Chem (2006) 1.66
Cophosphorylation of amphiphysin I and dynamin I by Cdk5 regulates clathrin-mediated endocytosis of synaptic vesicles. J Cell Biol (2003) 1.65
BANK regulates BCR-induced calcium mobilization by promoting tyrosine phosphorylation of IP(3) receptor. EMBO J (2002) 1.64
Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor. Mol Cell (2005) 1.62
Regulation of TRPC6 channel activity by tyrosine phosphorylation. J Biol Chem (2004) 1.61
IRBIT, an inositol 1,4,5-trisphosphate receptor-binding protein, specifically binds to and activates pancreas-type Na+/HCO3- cotransporter 1 (pNBC1). Proc Natl Acad Sci U S A (2006) 1.61
Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin. J Neurosci (2003) 1.58
Sustained activation of N-WASP through phosphorylation is essential for neurite extension. Dev Cell (2002) 1.58
Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth. Mol Cell Neurosci (2003) 1.57
Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones. Mol Cell Biol (2005) 1.56
The N-terminal Ca2+-independent calmodulin-binding site on the inositol 1,4,5-trisphosphate receptor is responsible for calmodulin inhibition, even though this inhibition requires Ca2+. Mol Pharmacol (2004) 1.56
Critical regions for activation gating of the inositol 1,4,5-trisphosphate receptor. J Biol Chem (2003) 1.53
Genotype-phenotype correlations in hereditary hemorrhagic telangiectasia: data from the French-Italian HHT network. Genet Med (2007) 1.52
Homer 1 mediates store- and inositol 1,4,5-trisphosphate receptor-dependent translocation and retrieval of TRPC3 to the plasma membrane. J Biol Chem (2006) 1.50
Potential link between amyloid beta-protein 42 and C-terminal fragment gamma 49-99 of beta-amyloid precursor protein. J Biol Chem (2003) 1.49
IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor. J Biol Chem (2003) 1.47
Hypersensitivity of nonhomologous DNA end-joining mutants to VP-16 and ICRF-193: implications for the repair of topoisomerase II-mediated DNA damage. J Biol Chem (2003) 1.47
Intrathecal treatment of anti-N-Methyl-D-aspartate receptor encephalitis in children. Dev Med Child Neurol (2014) 1.47
Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant. J Biol Chem (2005) 1.46
IRBIT suppresses IP3 receptor activity by competing with IP3 for the common binding site on the IP3 receptor. Mol Cell (2006) 1.46
Endothelin-1-stimulated InsP3-induced Ca2+ release is a nexus for hypertrophic signaling in cardiac myocytes. Mol Cell (2009) 1.42
Zic2 controls cerebellar development in cooperation with Zic1. J Neurosci (2002) 1.42
Cdk5/p35 is required for motor coordination and cerebellar plasticity. J Neurochem (2014) 1.42
Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Development (2007) 1.40
Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling. J Biol Chem (2004) 1.40
Single molecule-sensitive probes for imaging RNA in live cells. Nat Methods (2009) 1.40
Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling. J Neurosci (2006) 1.38
Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue. Gene (2003) 1.36
Neuroprotective effect of exogenous microglia in global brain ischemia. J Cereb Blood Flow Metab (2006) 1.35
Osteoblasts induce Ca2+ oscillation-independent NFATc1 activation during osteoclastogenesis. Proc Natl Acad Sci U S A (2008) 1.35
ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis. Proc Natl Acad Sci U S A (2011) 1.35
Abnormal taste perception in mice lacking the type 3 inositol 1,4,5-trisphosphate receptor. J Biol Chem (2007) 1.34
Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors. Proc Natl Acad Sci U S A (2009) 1.34
The IP3 receptor regulates cardiac hypertrophy in response to select stimuli. Circ Res (2010) 1.34
Structural basis for semaphorin signalling through the plexin receptor. Nature (2010) 1.33
Cytosolic inositol 1,4,5-trisphosphate dynamics during intracellular calcium oscillations in living cells. J Cell Biol (2006) 1.33
IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct. J Clin Invest (2008) 1.32
Motor dysfunction in type 5 adenylyl cyclase-null mice. J Biol Chem (2003) 1.32
Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42. Biochemistry (2004) 1.32
Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling. EMBO J (2002) 1.32
Nucleocytoplasmic shuttling and phosphorylation of BMAL1 are regulated by circadian clock in cultured fibroblasts. Genes Cells (2003) 1.31
Phosphorylation of zipcode binding protein 1 is required for brain-derived neurotrophic factor signaling of local beta-actin synthesis and growth cone turning. J Neurosci (2010) 1.29
Three-dimensional rearrangements within inositol 1,4,5-trisphosphate receptor by calcium. J Biol Chem (2003) 1.29
Two novel 2-aminoethyl diphenylborinate (2-APB) analogues differentially activate and inhibit store-operated Ca(2+) entry via STIM proteins. Cell Calcium (2009) 1.28
Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease. Hum Mol Genet (2006) 1.27
The autophagy-related kinase UNC-51 and its binding partner UNC-14 regulate the subcellular localization of the Netrin receptor UNC-5 in Caenorhabditis elegans. Development (2006) 1.27
Lateral diffusion of inositol 1,4,5-trisphosphate receptor type 1 is regulated by actin filaments and 4.1N in neuronal dendrites. J Biol Chem (2004) 1.26
C. elegans VAB-8 and UNC-73 regulate the SAX-3 receptor to direct cell and growth-cone migrations. Nat Neurosci (2007) 1.26
Mediolateral compartmentalization of the cerebellum is determined on the "birth date" of Purkinje cells. J Neurosci (2003) 1.26
Inositol 1,4,5-trisphosphate receptor contains multiple cavities and L-shaped ligand-binding domains. J Mol Biol (2004) 1.26
Regulation of spine development by semaphorin3A through cyclin-dependent kinase 5 phosphorylation of collapsin response mediator protein 1. J Neurosci (2007) 1.25
Early fibrinogen degradation coagulopathy is predictive of parenchymal hematomas in cerebral rt-PA thrombolysis: a study of 157 cases. Stroke (2004) 1.25
Differential expression of Homer family proteins in the developing mouse brain. J Comp Neurol (2004) 1.25
Cell signaling microdomain with Na,K-ATPase and inositol 1,4,5-trisphosphate receptor generates calcium oscillations. J Biol Chem (2003) 1.23
Initiation of embryonic cardiac pacemaker activity by inositol 1,4,5-trisphosphate-dependent calcium signaling. Mol Biol Cell (2005) 1.23
L1-dependent neuritogenesis involves ankyrinB that mediates L1-CAM coupling with retrograde actin flow. J Cell Biol (2003) 1.23
Kinesin dependent, rapid, bi-directional transport of ER sub-compartment in dendrites of hippocampal neurons. J Cell Sci (2004) 1.23
An RNA-interacting protein, SYNCRIP (heterogeneous nuclear ribonuclear protein Q1/NSAP1) is a component of mRNA granule transported with inositol 1,4,5-trisphosphate receptor type 1 mRNA in neuronal dendrites. J Biol Chem (2004) 1.23
Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. J Neurosci (2008) 1.23
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. PLoS One (2013) 1.23