Published in J Biol Chem on January 30, 2007
ABC transporters in cancer: more than just drug efflux pumps. Nat Rev Cancer (2010) 3.44
Genetic disorders of surfactant dysfunction. Pediatr Dev Pathol (2009) 1.77
The role of the photoreceptor ABC transporter ABCA4 in lipid transport and Stargardt macular degeneration. Biochim Biophys Acta (2009) 1.66
ATP-binding cassette transporter ABCA4: molecular properties and role in vision and macular degeneration. J Bioenerg Biomembr (2007) 1.54
Population and disease-based prevalence of the common mutations associated with surfactant deficiency. Pediatr Res (2008) 1.35
Some ABCA3 mutations elevate ER stress and initiate apoptosis of lung epithelial cells. Respir Res (2011) 1.28
Interstitial lung diseases in children. Orphanet J Rare Dis (2010) 1.28
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Genotype-phenotype correlations for infants and children with ABCA3 deficiency. Am J Respir Crit Care Med (2014) 1.23
ABCA12 maintains the epidermal lipid permeability barrier by facilitating formation of ceramide linoleic esters. J Biol Chem (2008) 1.21
rtTA toxicity limits the usefulness of the SP-C-rtTA transgenic mouse. Dev Biol (2008) 1.21
Surfactant dysfunction. Paediatr Respir Rev (2011) 1.16
An intronic ABCA3 mutation that is responsible for respiratory disease. Pediatr Res (2012) 1.11
Mammalian P4-ATPases and ABC transporters and their role in phospholipid transport. Biochim Biophys Acta (2012) 1.09
Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3. Proc Natl Acad Sci U S A (2011) 1.06
Defective lipid transport and biosynthesis in recessive and dominant Stargardt macular degeneration. Prog Lipid Res (2010) 0.99
A national internet-linked based database for pediatric interstitial lung diseases: the French network. Orphanet J Rare Dis (2012) 0.98
Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice. Am J Physiol Lung Cell Mol Physiol (2010) 0.95
ABC transporter A3 facilitates lysosomal sequestration of imatinib and modulates susceptibility of chronic myeloid leukemia cell lines to this drug. Haematologica (2009) 0.95
Comparative proteomic analysis of lung lamellar bodies and lysosome-related organelles. PLoS One (2011) 0.92
Conditional hypoxia inducible factor-1α induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis. Dev Biol (2011) 0.92
Intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol. Mol Biol Cell (2010) 0.91
A nonaggregating surfactant protein C mutant is misdirected to early endosomes and disrupts phospholipid recycling. Traffic (2011) 0.90
A-Subclass ATP-Binding Cassette Proteins in Brain Lipid Homeostasis and Neurodegeneration. Front Psychiatry (2012) 0.89
STAT3 regulates ABCA3 expression and influences lamellar body formation in alveolar type II cells. Am J Respir Cell Mol Biol (2007) 0.87
Hematopoietic stem cells exhibit a specific ABC transporter gene expression profile clearly distinct from other stem cells. BMC Pharmacol (2010) 0.87
A systems approach to mapping transcriptional networks controlling surfactant homeostasis. BMC Genomics (2010) 0.86
Misexpression of MIA disrupts lung morphogenesis and causes neonatal death. Dev Biol (2008) 0.84
Lost after translation: insights from pulmonary surfactant for understanding the role of alveolar epithelial dysfunction and cellular quality control in fibrotic lung disease. Am J Physiol Lung Cell Mol Physiol (2015) 0.83
Familial interstitial pulmonary fibrosis: a large family with atypical clinical features. Can Respir J (2010) 0.82
Disruption of N-linked glycosylation promotes proteasomal degradation of the human ATP-binding cassette transporter ABCA3. Am J Physiol Lung Cell Mol Physiol (2013) 0.82
Functional Characterization of ATP-Binding Cassette Transporter A3 Mutations from Infants with Respiratory Distress Syndrome. Am J Respir Cell Mol Biol (2016) 0.80
Structural Features of the ATP-Binding Cassette (ABC) Transporter ABCA3. Int J Mol Sci (2015) 0.79
Surfactant lipidomics in healthy children and childhood interstitial lung disease. PLoS One (2015) 0.78
Functional Validation of ABCA3 as a Miltefosine Transporter in Human Macrophages: IMPACT ON INTRACELLULAR SURVIVAL OF LEISHMANIA (VIANNIA) PANAMENSIS. J Biol Chem (2016) 0.78
Synonymous ABCA3 variants do not increase risk for neonatal respiratory distress syndrome. J Pediatr (2014) 0.77
Effect of hypoxia on lung gene expression and proteomic profile: insights into the pulmonary surfactant response. J Proteomics (2014) 0.77
Pneumocytes Assemble Lung Surfactant as Highly Packed/Dehydrated States with Optimal Surface Activity. Biophys J (2015) 0.77
Heterozygosity for E292V in ABCA3, lung function and COPD in 64,000 individuals. Respir Res (2012) 0.77
Impaired Lysosomal Integral Membrane Protein 2-dependent Peroxiredoxin 6 Delivery to Lamellar Bodies Accounts for Altered Alveolar Phospholipid Content in Adaptor Protein-3-deficient pearl Mice. J Biol Chem (2016) 0.76
Mature Surfactant Protein-B Expression by Immunohistochemistry as a Marker for Surfactant System Development in the Fetal Sheep Lung. J Histochem Cytochem (2015) 0.76
Cellular mechanisms of alveolar pathology in childhood interstitial lung diseases: current insights from mouse genetics. Curr Opin Pediatr (2015) 0.75
Respiratory failure in a term infant with cis and trans mutations in ABCA3. J Perinatol (2015) 0.75
The biology of the ABCA3 lipid transporter in lung health and disease. Cell Tissue Res (2016) 0.75
Disruption of sorting nexin 5 causes respiratory failure associated with undifferentiated alveolar epithelial type I cells in mice. PLoS One (2013) 0.75
A three-dimensional model of human lung development and disease from pluripotent stem cells. Nat Cell Biol (2017) 0.75
Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation. Respir Res (2017) 0.75
When is an Alveolar Type 2 Cell an Alveolar Type 2 Cell? A Conundrum for Lung Stem Cell Biology and Regenerative Medicine. Am J Respir Cell Mol Biol (2017) 0.75
Effect of cigarette smoke extract on insulin transport in alveolar epithelial cell line A549. Lung (2012) 0.75
Cancer cachexia alters intracellular surfactant metabolism but not total alveolar surface area. Histochem Cell Biol (2012) 0.75
Outcomes of Lung Transplantation for Infants and Children with Genetic Disorders of Surfactant Metabolism. J Pediatr (2017) 0.75
Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. J Cell Biol (2002) 5.52
Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses? Arch Neurol (2003) 3.75
LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing. Nature (2005) 3.35
Modified double-K method for intraocular lens power calculation after excimer laser corneal refractive surgery. J Cataract Refract Surg (2013) 3.29
The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza. Cell (2013) 3.19
Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist. Proc Natl Acad Sci U S A (2002) 3.01
Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid. J Biol Chem (2006) 2.79
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. Nat Chem Biol (2009) 2.70
Serum lysophosphatidic acid is produced through diverse phospholipase pathways. J Biol Chem (2002) 2.42
No forward shifting of posterior corneal surface in eyes undergoing LASIK. Ophthalmology (2007) 2.21
Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1. J Biol Chem (2004) 2.17
Impaired α-TTP-PIPs interaction underlies familial vitamin E deficiency. Science (2013) 2.15
TGFα shedding assay: an accurate and versatile method for detecting GPCR activation. Nat Methods (2012) 2.04
Vitamin E decreases bone mass by stimulating osteoclast fusion. Nat Med (2012) 2.04
Fall prevention using olfactory stimulation with lavender odor in elderly nursing home residents: a randomized controlled trial. J Am Geriatr Soc (2012) 2.03
Subcortical hematoma caused by cerebral amyloid angiopathy: does the first evidence of hemorrhage occur in the subarachnoid space? Neuropathology (2003) 1.99
The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers. Alzheimers Dement (2011) 1.87
Stepwise insertion and inversion of a type II signal anchor sequence in the ribosome-Sec61 translocon complex. Cell (2011) 1.86
Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation. Cell Metab (2012) 1.77
The MAP1-LC3 conjugation system is involved in lipid droplet formation. Biochem Biophys Res Commun (2009) 1.77
The anti-inflammatory and proresolving mediator resolvin E1 protects mice from bacterial pneumonia and acute lung injury. J Immunol (2009) 1.71
Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding. Hum Mol Genet (2008) 1.60
Impact of quality as well as quantity of skeletal muscle on outcomes after liver transplantation. Liver Transpl (2014) 1.58
Novel 18F-labeled arylquinoline derivatives for noninvasive imaging of tau pathology in Alzheimer disease. J Nucl Med (2013) 1.58
DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1. Hum Mol Genet (2006) 1.58
Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid. J Biol Chem (2006) 1.55
Localization of mouse mitochondrial SIRT proteins: shift of SIRT3 to nucleus by co-expression with SIRT5. Biochem Biophys Res Commun (2007) 1.54
A real-time method of imaging glucose uptake in single, living mammalian cells. Nat Protoc (2007) 1.52
Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1. J Lipid Res (2006) 1.52
A randomized, observer-blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms and activities of daily living in dementia patients. J Clin Psychiatry (2005) 1.51
A novel phosphatidic acid-selective phospholipase A1 that produces lysophosphatidic acid. J Biol Chem (2002) 1.49
Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer. Lab Invest (2004) 1.49
Decrease in membrane phospholipid unsaturation induces unfolded protein response. J Biol Chem (2010) 1.48
Cerebrospinal fluid tau protein and periventricular white matter lesions in patients with mild cognitive impairment: implications for 2 major pathways. Arch Neurol (2004) 1.48
LPA-producing enzyme PA-PLA₁α regulates hair follicle development by modulating EGFR signalling. EMBO J (2011) 1.48
Transcriptome Analysis of K-877 (a Novel Selective PPARα Modulator (SPPARMα))-Regulated Genes in Primary Human Hepatocytes and the Mouse Liver. J Atheroscler Thromb (2015) 1.45
The murine glucagon-like peptide-1 receptor is essential for control of bone resorption. Endocrinology (2007) 1.45
Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project 1. Am J Clin Nutr (2006) 1.45
Impaired efficacy of cough in patients with Parkinson disease. Chest (2003) 1.44
Exendin-4 suppresses SRC activation and reactive oxygen species production in diabetic Goto-Kakizaki rat islets in an Epac-dependent manner. Diabetes (2010) 1.43
Systems analysis of GLP-1 receptor signaling in pancreatic β-cells. Am J Physiol Cell Physiol (2011) 1.42
Ocular integrity after anterior ciliary sclerotomy and scleral ablation by the Er:YAG laser. J Refract Surg (2005) 1.41
Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231. Arch Neurol (2002) 1.41
Effect of age on changes in anterior chamber depth and volume after laser in situ keratomileusis. J Cataract Refract Surg (2009) 1.41
Quinoline and benzimidazole derivatives: candidate probes for in vivo imaging of tau pathology in Alzheimer's disease. J Neurosci (2005) 1.38
The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site. FEBS Lett (2003) 1.38
2-(2-[2-Dimethylaminothiazol-5-yl]ethenyl)-6- (2-[fluoro]ethoxy)benzoxazole: a novel PET agent for in vivo detection of dense amyloid plaques in Alzheimer's disease patients. J Nucl Med (2007) 1.37
Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells. Am J Pathol (2006) 1.33
Caenorhabditis elegans mboa-7, a member of the MBOAT family, is required for selective incorporation of polyunsaturated fatty acids into phosphatidylinositol. Mol Biol Cell (2007) 1.31
Both plasma lysophosphatidic acid and serum autotaxin levels are increased in chronic hepatitis C. J Clin Gastroenterol (2007) 1.29
Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma. Breast Cancer Res (2004) 1.29
The anaerobic regulatory network required for Pseudomonas aeruginosa nitrate respiration. J Bacteriol (2007) 1.29
Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease. Hum Mol Genet (2006) 1.27
Transgenic expression of group V, but not group X, secreted phospholipase A2 in mice leads to neonatal lethality because of lung dysfunction. J Biol Chem (2006) 1.25
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. PLoS One (2013) 1.23
Eosinophils promote resolution of acute peritonitis by producing proresolving mediators in mice. FASEB J (2010) 1.22
Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates and diphosphates: a potential route to new bone antiresorption and antiparasitic agents. J Med Chem (2002) 1.22
Analysis of factors influencing pancreatic beta-cell function in Japanese patients with type 2 diabetes: association with body mass index and duration of diabetic exposure. Diabetes Res Clin Pract (2008) 1.22
ADRP/adipophilin is degraded through the proteasome-dependent pathway during regression of lipid-storing cells. J Lipid Res (2005) 1.22
Human ABCA3, a product of a responsible gene for abca3 for fatal surfactant deficiency in newborns, exhibits unique ATP hydrolysis activity and generates intracellular multilamellar vesicles. Biochem Biophys Res Commun (2004) 1.20
Characterization and classification of ATP-binding cassette transporter ABCA3 mutants in fatal surfactant deficiency. J Biol Chem (2006) 1.20
Identification and structure determination of novel anti-inflammatory mediator resolvin E3, 17,18-dihydroxyeicosapentaenoic acid. J Biol Chem (2012) 1.19
LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation. Biochem Biophys Res Commun (2010) 1.18
Comparison of the binding characteristics of [18F]THK-523 and other amyloid imaging tracers to Alzheimer's disease pathology. Eur J Nucl Med Mol Imaging (2012) 1.18
Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family. J Biol Chem (2005) 1.17
Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysis. Diabetes (2006) 1.17
Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes. Proc Natl Acad Sci U S A (2011) 1.16
CO2-responsive expression and gene organization of three ribulose-1,5-bisphosphate carboxylase/oxygenase enzymes and carboxysomes in Hydrogenovibrio marinus strain MH-110. J Bacteriol (2004) 1.16
Vascular remodeling induced by naturally occurring unsaturated lysophosphatidic acid in vivo. Circulation (2003) 1.16
SUIT, secretory units of islets in transplantation: An index for therapeutic management of islet transplanted patients and its application to type 2 diabetes. Diabetes Res Clin Pract (2006) 1.16
Centrosomal Aki1 and cohesin function in separase-regulated centriole disengagement. J Cell Biol (2009) 1.15
Genetic association of CTNNA3 with late-onset Alzheimer's disease in females. Hum Mol Genet (2007) 1.15
Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide. J Biol Chem (2004) 1.15
ABCA3-mediated choline-phospholipids uptake into intracellular vesicles in A549 cells. FEBS Lett (2007) 1.13
Disruption of TBP-2 ameliorates insulin sensitivity and secretion without affecting obesity. Nat Commun (2010) 1.13
Characterization of a bifunctional archaeal acyl coenzyme A carboxylase. J Bacteriol (2003) 1.13
Molecular and cellular characteristics of ABCA3 mutations associated with diffuse parenchymal lung diseases in children. Hum Mol Genet (2011) 1.12
PRMT5, a novel TRAIL receptor-binding protein, inhibits TRAIL-induced apoptosis via nuclear factor-kappaB activation. Mol Cancer Res (2009) 1.12
Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese. Genomics (2009) 1.12
Male elderly subthreshold depression patients have smaller volume of medial part of prefrontal cortex and precentral gyrus compared with age-matched normal subjects: a voxel-based morphometry. J Affect Disord (2005) 1.11
Sequence-specific retention and regulated integration of a nascent membrane protein by the endoplasmic reticulum Sec61 translocon. Mol Biol Cell (2008) 1.11
A novel phospholipase A1 with sequence homology to a mammalian Sec23p-interacting protein, p125. J Biol Chem (2002) 1.11
Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation. Clin Chim Acta (2007) 1.11
Protection against oxidative stress-induced hepatic injury by intracellular type II platelet-activating factor acetylhydrolase by metabolism of oxidized phospholipids in vivo. J Biol Chem (2007) 1.10
Neuroprotection by KATP channels. J Mol Cell Cardiol (2005) 1.10
Beneficial effects of exendin-4 on experimental polyneuropathy in diabetic mice. Diabetes (2011) 1.10
GLP-1 receptor antagonist as a potential probe for pancreatic beta-cell imaging. Biochem Biophys Res Commun (2009) 1.10
Fibrates down-regulate hepatic scavenger receptor class B type I protein expression in mice. J Biol Chem (2003) 1.10
Intracellular phospholipase A1gamma (iPLA1gamma) is a novel factor involved in coat protein complex I- and Rab6-independent retrograde transport between the endoplasmic reticulum and the Golgi complex. J Biol Chem (2009) 1.09
Autotaxin regulates vascular development via multiple lysophosphatidic acid (LPA) receptors in zebrafish. J Biol Chem (2011) 1.08
Erythropoietin promotes the growth of tumors lacking its receptor and decreases survival of tumor-bearing mice by enhancing angiogenesis. Neoplasia (2008) 1.08