Published in Nature on June 06, 1991
Interstitial cells of Cajal mediate inhibitory neurotransmission in the stomach. Proc Natl Acad Sci U S A (1996) 4.01
Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme. Proc Natl Acad Sci U S A (1992) 3.95
Brainstem circuits regulating gastric function. Annu Rev Physiol (2006) 2.57
Loss of enteric motor neurotransmission in the gastric fundus of Sl/Sl(d) mice. J Physiol (2002) 1.68
Effect of atropine on proximal gastric motor and sensory function in normal subjects. Gut (2000) 1.67
Nitric oxide involvement in the peptide VIP-associated inhibitory junction potential in the guinea-pig ileum. J Physiol (1993) 1.57
Esophageal-gastric relaxation reflex in rat: dual control of peripheral nitrergic and cholinergic transmission. Am J Physiol Regul Integr Comp Physiol (2006) 1.56
Nitric oxide activates multiple potassium channels in canine colonic smooth muscle. J Physiol (1995) 1.55
Nerve mediated relaxation of the human internal anal sphincter: the role of nitric oxide. Gut (1993) 1.47
Chemical synthesis of nitric oxide in the stomach from dietary nitrate in humans. Gut (1997) 1.46
Nitric oxide-dependent penile erection in mice lacking neuronal nitric oxide synthase. Mol Med (1996) 1.45
Characterization of vagal pathways mediating gastric accommodation reflex in rats. J Physiol (1997) 1.45
Intraganglionic laminar endings are mechano-transduction sites of vagal tension receptors in the guinea-pig stomach. J Physiol (2001) 1.43
Influence of sumatriptan on gastric fundus tone and on the perception of gastric distension in man. Gut (2000) 1.34
Vagal control of nitric oxide and vasoactive intestinal polypeptide release in the regulation of gastric relaxation in rat. J Physiol (1995) 1.29
Involvement of cyclic GMP in non-adrenergic, non-cholinergic inhibitory neurotransmission in dog proximal colon. Br J Pharmacol (1992) 1.25
Relations between upper abdominal symptoms and gastric distension abnormalities in dysmotility like functional dyspepsia and after vagotomy. Gut (1995) 1.20
Endogenous nitric oxide and sensory neuropeptides interact in the modulation of the rat gastric microcirculation. Br J Pharmacol (1992) 1.17
Thirteenth Gaddum Memorial Lecture. Neuronal and endothelium-derived mediators in the modulation of the gastric microcirculation: integrity in the balance. Br J Pharmacol (1993) 1.14
Accommodation mediated by enteric inhibitory reflexes in the isolated guinea-pig small intestine. J Physiol (1994) 1.14
Nitric oxide in health and disease of the nervous system. Antioxid Redox Signal (2009) 1.13
Nitroxergic nerves mediate vagally induced relaxation in the isolated stomach of the guinea pig. Proc Natl Acad Sci U S A (1991) 1.12
Influence of NG-nitro-L-arginine on non-adrenergic non-cholinergic relaxation in the guinea-pig gastric fundus. Br J Pharmacol (1992) 1.10
Inhibitors of nitric oxide synthetase prevent castor-oil-induced diarrhoea in the rat. Br J Pharmacol (1993) 1.10
Nitric oxide-dependent release of vasodilator quantities of calcitonin gene-related peptide from capsaicin-sensitive nerves in rabbit skin. Br J Pharmacol (1994) 1.08
Excitatory and inhibitory motor reflexes in the isolated guinea-pig stomach. J Physiol (1997) 1.08
Musings on the wanderer: what's new in our understanding of vago-vagal reflexes? III. Activity-dependent plasticity in vago-vagal reflexes controlling the stomach. Am J Physiol Gastrointest Liver Physiol (2003) 1.07
In vitro and in vivo analysis of the effects of corticotropin releasing factor on rat dorsal vagal complex. J Physiol (2002) 1.06
Nitric oxide synthase neurones and neuromuscular behaviour of the anorectum. Ann R Coll Surg Engl (1998) 1.05
Mediation by nitric oxide of neurogenic relaxation of the urinary bladder neck muscle in sheep. J Physiol (1992) 1.03
Role of nitric oxide- and vasoactive intestinal polypeptide-containing neurones in human gastric fundus strip relaxations. Br J Pharmacol (2000) 1.02
NANC inhibitory neurotransmission in mouse isolated stomach: involvement of nitric oxide, ATP and vasoactive intestinal polypeptide. Br J Pharmacol (2003) 1.01
Modulation of cholinergic and substance P-like neurotransmission by nitric oxide in the guinea-pig ileum. Br J Pharmacol (1993) 1.01
Nitric oxide-mediated inhibitory response of rat proximal colon: independence from changes in membrane potential. Br J Pharmacol (1994) 0.98
Nitric oxide, and not vasoactive intestinal peptide, as the main neurotransmitter of vagally induced relaxation of the guinea pig stomach. Br J Pharmacol (1994) 0.98
Effects of brain stem cholecystokinin-8s on gastric tone and esophageal-gastric reflex. Am J Physiol Gastrointest Liver Physiol (2009) 0.95
Mechanosensitive enteric neurons in the myenteric plexus of the mouse intestine. PLoS One (2012) 0.95
Neural mechanisms of peristalsis in the isolated rabbit distal colon: a neuromechanical loop hypothesis. Front Neurosci (2014) 0.95
Inhibition of sphincter of Oddi function by the nitric oxide carrier S-nitroso-N-acetylcysteine in rabbits and humans. J Clin Invest (1994) 0.94
Nitric oxide permits hypoxia-induced lymphatic perfusion by controlling arterial-lymphatic conduits in zebrafish and glass catfish. Proc Natl Acad Sci U S A (2009) 0.94
Serotonergic modulating drugs for functional gastrointestinal diseases. Br J Clin Pharmacol (2002) 0.93
Parallel pathways mediate inhibitory effects of vasoactive intestinal polypeptide and nitric oxide in canine fundus. Br J Pharmacol (1999) 0.93
Influence of NG-nitro-L-arginine methyl ester on vagally induced gastric relaxation in the anaesthetized rat. Br J Pharmacol (1992) 0.93
Gastric accommodation studied by ultrasonography in patients with reflux esophagitis. Dig Dis Sci (2001) 0.92
L-NAME, nitric oxide and jejunal motility, blood flow and oxygen uptake in dogs. Br J Pharmacol (1994) 0.92
Gastrointestinal motility changes and myenteric plexus alterations in spontaneously diabetic biobreeding rats. J Neurogastroenterol Motil (2013) 0.91
Role of nitric oxide in the gastric accommodation reflex and in meal induced satiety in humans. Gut (2002) 0.90
Relation between cholecystokinin and antral innervation in the control of gastric emptying in the rat. Gut (1997) 0.90
Nitric oxide synthase in pig lower urinary tract: immunohistochemistry, NADPH diaphorase histochemistry and functional effects. Br J Pharmacol (1993) 0.89
Actions and interactions of NG-substituted analogues of L-arginine on NANC neurotransmission in the bovine retractor penis and rat anococcygeus muscles. Br J Pharmacol (1993) 0.89
Nitric oxide affects mammalian distal colonic smooth muscle by tonic neural inhibition. Br J Pharmacol (1993) 0.88
Impaired gastric relaxation in patients with achalasia. Gut (1995) 0.87
Effects of glucagon-like peptide-1 and sympathetic stimulation on gastric accommodation in humans. Neurogastroenterol Motil (2007) 0.87
Gastric accommodation assessed by ultrasonography. World J Gastroenterol (2006) 0.87
The effect of nitric oxide on the efficacy of synaptic transmission through the chick ciliary ganglion. Br J Pharmacol (1993) 0.87
Effect of glyceryl trinitrate on gastric accommodation and symptoms in functional dyspepsia. Dig Dis Sci (1997) 0.86
Modulation by nitric oxide of spontaneous motility of the rat isolated duodenum: role of tachykinins. Br J Pharmacol (1996) 0.85
Nitric Oxide-mediated Relaxation by High K in Human Gastric Longitudinal Smooth Muscle. Korean J Physiol Pharmacol (2011) 0.85
Effect of modulation of serotonergic, cholinergic, and nitrergic pathways on murine fundic size and compliance measured by ultrasonomicrometry. Am J Physiol Gastrointest Liver Physiol (2005) 0.84
Proximal gastric response to small intestinal nutrients is abnormal in mechanically ventilated critically ill patients. World J Gastroenterol (2006) 0.84
Nicotinic receptor mediates nitric oxide synthase expression in the rat gastric myenteric plexus. J Clin Invest (1998) 0.84
Dissociation between electrical and mechanical responses to nitrergic stimulation in the canine gastric fundus. J Physiol (1998) 0.84
Efficacy of mosapride citrate in proximal gastric accommodation and gastrointestinal motility in healthy volunteers: a double-blind placebo-controlled ultrasonographic study. J Gastroenterol (2010) 0.84
Interactions of nitric oxide synthase inhibitors and dexamethasone with alpha-adrenoceptor-mediated responses in rat aorta. Br J Pharmacol (1993) 0.83
Impairment of nitrergic-mediated relaxation of rat isolated duodenum by experimental diabetes. Br J Pharmacol (1995) 0.83
Low plasma nitrite in infantile hypertrophic pyloric stenosis patients. Dig Dis Sci (2006) 0.82
Smooth muscle relaxing effects of NO, nitrosothiols and a nerve-induced relaxing factor released in guinea-pig colon. Br J Pharmacol (1994) 0.82
Secretin-induced gastric relaxation is mediated by vasoactive intestinal polypeptide and prostaglandin pathways. Neurogastroenterol Motil (2009) 0.81
Gastric motility in soluble guanylate cyclase alpha 1 knock-out mice. J Physiol (2007) 0.81
Effect of the nitric oxide donor, glyceryl trinitrate, on human gall bladder motility. Gut (1998) 0.80
Gastric sensitivity and reflexes: basic mechanisms underlying clinical problems. J Gastroenterol (2013) 0.79
Upregulation of bile acid receptor TGR5 and nNOS in gastric myenteric plexus is responsible for delayed gastric emptying after chronic high-fat feeding in rats. Am J Physiol Gastrointest Liver Physiol (2014) 0.78
Evidence for VIP(1)/PACAP receptors in the afferent pathway mediating surgery-induced fundic relaxation in the rat. Br J Pharmacol (2000) 0.78
Altered messenger RNA expression of the neuronal nitric oxide synthase gene in infantile hypertrophic pyloric stenosis. Pediatr Surg Int (1997) 0.78
Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice. Nat Commun (2015) 0.78
Sildenafil, a phosphodiesterase-5 inhibitor, delays gastric emptying and gastrointestinal transit of liquid in awake rats. Dig Dis Sci (2003) 0.78
Nitric oxide is involved in 5-HT-induced relaxations of the guinea-pig colon ascendens in vitro. Br J Pharmacol (1992) 0.78
Effect of intraduodenal and intravenous amino acids on proximal gastric motor function in man. Dig Dis Sci (2001) 0.77
Functional Dyspepsia: Impaired Fundic Accommodation. Curr Treat Options Gastroenterol (2000) 0.77
High k(+)-induced relaxation by nitric oxide in human gastric fundus. Korean J Physiol Pharmacol (2012) 0.77
Nitric oxide synthase gene polymorphisms in functional dyspepsia. Dig Dis Sci (2013) 0.77
Heme deficiency of soluble guanylate cyclase induces gastroparesis. Neurogastroenterol Motil (2013) 0.77
Ulster says 'NO'; explosion, resistance and tolerance. Nitric oxide and the actions of organic nitrates. Ulster Med J (1998) 0.77
Gastric nNOS reduction accompanied by natriuretic peptides signaling pathway upregulation in diabetic mice. World J Gastroenterol (2014) 0.76
Effects of intragastric L-arginine administration on proximal stomach tone under basal conditions and after an intragastric diet. Dig Dis Sci (2006) 0.76
H2S, a novel gasotransmitter, involves in gastric accommodation. Sci Rep (2015) 0.75
Inhibitory responses mediated by vagal nerve stimulation are diminished in stomachs of mice with reduced intramuscular interstitial cells of Cajal. Sci Rep (2017) 0.75
Nitrergic Pathway Is the Main Contributing Mechanism in the Human Gastric Fundus Relaxation: An In Vitro Study. PLoS One (2016) 0.75
Increase in nitric oxide and cyclic GMP of rat cerebellum by radio frequency burst-type electromagnetic field radiation. J Physiol (1993) 0.75
Endocrine and metabolic changes in human aging. J Am Aging Assoc (2000) 0.75
Influence of amino acids on gastric adaptive relaxation (accommodation) in rats as evaluated with a barostat. J Smooth Muscle Res (2016) 0.75
5-HT3 receptors do not mediate vagally-induced relaxation or contraction of the isolated stomach of the guinea-pig. Br J Pharmacol (1994) 0.75
Convergence of inhibitory neural inputs regulate motor activity in the murine and monkey stomach. Am J Physiol Gastrointest Liver Physiol (2016) 0.75
Effect of colonic distension on gastric adaptive relaxation in rats: barostatic evaluation using an orally introduced gastric balloon. J Smooth Muscle Res (2014) 0.75
Vagal neurocircuitry and its influence on gastric motility. Nat Rev Gastroenterol Hepatol (2016) 0.75
Proximal Gastric Dysfunction in Functional Dyspepsia: Management Options. Curr Treat Options Gastroenterol (2004) 0.75
Effect of biliary cirrhosis on neurogenic relaxation of rat gastric fundus and anococcygeus muscle: role of nitric oxide pathway. Dig Dis Sci (2014) 0.75
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol (1971) 37.53
Release of additional factors in anaphylaxis and its antagonism by anti-inflammatory drugs. Nature (1969) 13.60
An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature (1976) 13.19
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature (1999) 11.37
Prostaglandins: their disappearance from and release into the circulation. Nature (1967) 8.66
The release and fate of vaso-active hormones in the circulation. Br J Pharmacol (1969) 7.90
Prostaglandins released by the spleen. Nature (1968) 7.61
Biological action of leptin as an angiogenic factor. Science (1998) 6.02
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci U S A (1999) 5.96
Elevated blood pressures in mice lacking endothelial nitric oxide synthase. Proc Natl Acad Sci U S A (1996) 5.94
The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nat Med (2000) 5.72
Indomethacin and aspirin abolish prostaglandin release from the spleen. Nat New Biol (1971) 5.62
Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest (1997) 4.92
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci U S A (1993) 4.82
Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor. Proc Natl Acad Sci U S A (1988) 4.77
Caveolins, liquid-ordered domains, and signal transduction. Mol Cell Biol (1999) 4.70
Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin. Pharmacol Rev (1978) 4.66
Dynamic activation of endothelial nitric oxide synthase by Hsp90. Nature (1998) 4.65
Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac ateries and inhibits platelet aggregation. Prostaglandins (1976) 4.54
Inactivation of prostaglandins by the lungs. Nature (1970) 4.47
Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides. Prostaglandins (1976) 4.44
Human arterial and venous tissues generate prostacyclin (prostaglandin x), a potent inhibitor of platelet aggregation. Lancet (1977) 4.11
Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling. Proc Natl Acad Sci U S A (1996) 3.83
Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the nos caveolin binding domain in vivo. J Biol Chem (1997) 3.80
Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets. Prostaglandins (1977) 3.74
Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis? Lancet (1978) 3.74
Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. J Clin Invest (1998) 3.71
The chemical structure of prostaglandin X (prostacyclin). Prostaglandins (1976) 3.63
Effects of anti-inflammatory drugs on prostaglandin biosynthesis. Nat New Biol (1972) 3.54
In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation. Nat Med (2000) 3.37
Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol). Nature (1972) 3.30
Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway. J Biol Chem (2000) 3.30
Arachidonic acid metabolites and the interactions between platelets and blood-vessel walls. N Engl J Med (1979) 3.29
Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium. Thromb Res (1977) 3.28
Prostaglandins, aspirin-like drugs and the oedema of inflammation. Nature (1973) 3.20
Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells. Circ Res (2000) 3.12
Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1. J Biol Chem (1996) 3.01
A new approach to anti-inflammatory drugs. Biochem Pharmacol (1979) 2.95
Receptor-mediated release of endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells is coupled. Proc Natl Acad Sci U S A (1988) 2.84
Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides. Nature (1976) 2.83
Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough? J Pharmacol Exp Ther (2001) 2.74
Prostacyclin (PGX) is the endogenous metabolite responsible for relaxation of coronary arteries induced by arachindonic acid. Prostaglandins (1977) 2.67
The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: cultured endothelial cells recycle L-citrulline to L-arginine. Proc Natl Acad Sci U S A (1990) 2.63
Pharmacokinetic function of the pulmonary circulation. Physiol Rev (1974) 2.52
The release of prostaglandins and rabbit aorta contracting substance (RCS) from rabbit spleen and its antagonism by anti-inflammatory drugs. Br J Pharmacol (1972) 2.52
Unstable metabolites of arachidonic acid and their role in haemostasis and thrombosis. Br Med Bull (1978) 2.51
Prostaglandins, oxygen tension and smooth muscle tone. Br J Pharmacol (1972) 2.51
Intrarenal prostaglandin release attenuates the renal vasoconstrictor activity of angiotensin. J Pharmacol Exp Ther (1973) 2.48
Imidazole: a selective inhibitor of thromboxane synthetase. Prostaglandins (1977) 2.48
The disappearance of bradykinin and eledoisin in the circulation and vascular beds of the cat. Br J Pharmacol Chemother (1967) 2.44
Release of rabbit aorta contracting substance (RCS) and prostaglandins induced by chemical or mechanical stimulation of guinea-pig lungs. Br J Pharmacol (1973) 2.42
Phospholipase A2 activity of guinea-pig isolated perfused lungs: stimulation, and inhibition by anti-inflammatory steroids. Br J Pharmacol (1978) 2.41
Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt. Circ Res (2000) 2.39
The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure. Proc Natl Acad Sci U S A (1995) 2.36
The contribution of prostaglandin production to contractions of the isolated uterus of the rat. Br J Pharmacol (1973) 2.33
Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors. Lab Invest (1999) 2.32
Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock. Br J Pharmacol (1993) 2.32
A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation. Prostaglandins (1976) 2.28
Conversion of angiotensin I to angiotensin II. Nature (1967) 2.26
Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa. Nature (1980) 2.24
Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1. J Biol Chem (2000) 2.23
Release of prostaglandin E-1 from the rat stomach. Nature (1967) 2.13
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis. Mol Cell (2001) 2.11
Enhanced electron flux and reduced calmodulin dissociation may explain "calcium-independent" eNOS activation by phosphorylation. J Biol Chem (2000) 2.10
Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor. Proc Natl Acad Sci U S A (1989) 2.08
Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs. Br J Pharmacol (1973) 2.07
The effects of prostagladin endoperoxides and thromboxane A2 on strips of rabbit coeliac artery and certain other smooth muscle preparations [proceedings]. Br J Pharmacol (1976) 2.06
The release of catechol amines from the adrenal medulla by histamine. Br J Pharmacol Chemother (1965) 2.00
Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide. Proc Natl Acad Sci U S A (1993) 1.96
Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat. Eur J Pharmacol (1989) 1.95
Fate of angiotensin I in the circulation. Nature (1968) 1.94
Endothelial cells metabolize NG-monomethyl-L-arginine to L-citrulline and subsequently to L-arginine. Biochem Biophys Res Commun (1990) 1.94
Metabolism of the angiotensins in isolated perfused tissues. Nature (1969) 1.91
The first 35 amino acids and fatty acylation sites determine the molecular targeting of endothelial nitric oxide synthase into the Golgi region of cells: a green fluorescent protein study. J Cell Biol (1997) 1.89
5-hydroxytryptamine in the circulation of the dog. Nature (1967) 1.88
High endothelin-1 immunoreactivity in Crohn's disease and ulcerative colitis. Lancet (1992) 1.88
The distribution and metabolism of arachidonic acid in rabbit platelets during aggregation and its modification by drugs. Br J Pharmacol (1977) 1.87
Comparison of the effects of prostacyclin (PGI2), prostaglandin E1 and D2 on platelet aggregation in different species. Prostaglandins (1978) 1.85
Comparison of the vasodepressor effects of prostacyclin and 6-oxo-prostaglandin F1alpha with those of prostaglandin E2 in rats and rabbits. Br J Pharmacol (1978) 1.85
Heat shock protein 90 mediates the balance of nitric oxide and superoxide anion from endothelial nitric-oxide synthase. J Biol Chem (2001) 1.82
Induction of cyclo-oxygenase-2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone. Br J Pharmacol (1994) 1.82
Palmitoylation of endothelial nitric oxide synthase is necessary for optimal stimulated release of nitric oxide: implications for caveolae localization. Biochemistry (1996) 1.81
Proceedings: Prostaglandin generation maintains the smooth muscle tone of the rabbit isolated jejunum. Br J Pharmacol (1972) 1.80
The detection and estimation of bradykinin in the circulating blood. Br J Pharmacol Chemother (1967) 1.80
Pharmacokinetics of aspirin and salicylate in relation to inhibition of arachidonate cyclooxygenase and antiinflammatory activity. Proc Natl Acad Sci U S A (1987) 1.80
Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion. Circ Res (1995) 1.76
Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells. J Biol Chem (2001) 1.72
Characterization of bovine endothelial nitric oxide synthase expressed in E. coli. Biochem Biophys Res Commun (1996) 1.71
The synergistic activity of alphavbeta3 integrin and PDGF receptor increases cell migration. J Cell Sci (1998) 1.70
Functional analysis of the human endothelial nitric oxide synthase promoter. Sp1 and GATA factors are necessary for basal transcription in endothelial cells. J Biol Chem (1995) 1.69
The effects of alteration of blood-volume on the concentration of circulating angiotensin in anaesthetized dogs. J Physiol (1966) 1.66
Partial purification of rabbit aorta contracting substance-releasing factor and inhibition of its activity by anti-inflammatory steroids. Nature (1976) 1.65
Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells. J Biol Chem (2001) 1.65
The generation from arachidonic acid of rabbit aorta contracting substance (RCS) by a microsomal enzyme preparation which also generates prostaglandins. Br J Pharmacol (1972) 1.65
Co-induction of nitric oxide synthase and cyclo-oxygenase: interactions between nitric oxide and prostanoids. Br J Pharmacol (1995) 1.63
17 beta-estradiol regulation of human endothelial cell basal nitric oxide release, independent of cytosolic Ca2+ mobilization. Circ Res (1997) 1.63
Prostacyclin is a circulating hormone. Nature (1978) 1.60
Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat. Gastroenterology (1999) 1.58
Synthesis of 6-keto-PGF1alpha by ram seminal vesicle microsomes. Prostaglandins (1977) 1.57