Published in Stroke on June 29, 2006
Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery. Nat Med (2009) 2.76
Hypertension and cerebrovascular dysfunction. Cell Metab (2008) 2.30
Rho kinase inhibition rescues the endothelial cell cerebral cavernous malformation phenotype. J Biol Chem (2010) 1.51
Hyperglycemia, diabetes and stroke: focus on the cerebrovasculature. Vascul Pharmacol (2009) 1.14
Inhibition of Rho kinase by hydroxyfasudil attenuates brain edema after subarachnoid hemorrhage in rats. Neurochem Int (2011) 1.05
Update on statin-mediated anti-inflammatory activities in atherosclerosis. Semin Immunopathol (2009) 1.04
FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2. FASEB J (2012) 0.95
Postischemic reperfusion causes smooth muscle calcium sensitization and vasoconstriction of parenchymal arterioles. Stroke (2014) 0.84
HIV-1 Tat-induced cerebrovascular toxicity is enhanced in mice with amyloid deposits. Neurobiol Aging (2011) 0.81
New approaches to the treatment of pulmonary hypertension: from bench to bedside. Cardiol Rev (2010) 0.80
Hypersensitivity to thromboxane receptor mediated cerebral vasomotion and CBF oscillations during acute NO-deficiency in rats. PLoS One (2010) 0.79
Suppression of the Rho/Rho-kinase pathway and prevention of cerebral vasospasm by combination treatment with statin and fasudil after subarachnoid hemorrhage in rabbit. Transl Stroke Res (2013) 0.78
Efficacy of Rho kinase inhibitor on cognitive impairment induced by chronic cerebral hypoperfusion in rats. Int J Clin Exp Med (2015) 0.76
Alteration of basilar artery rho-kinase and soluble guanylyl cyclase protein expression in a rat model of cerebral vasospasm following subarachnoid hemorrhage. Biomed Res Int (2014) 0.75
Role of the Rho GTPase/Rho kinase signaling pathway in pathogenesis and treatment of glaucoma: Bench to bedside research. Exp Eye Res (2016) 0.75
Concepts and hypothesis: integrin cytoplasmic domain-associated protein-1 (ICAP-1) as a potential player in cerebral cavernous malformation. J Neurol (2012) 0.75
Apoptotic mechanisms after cerebral ischemia. Stroke (2009) 3.92
Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat Rev Drug Discov (2011) 3.08
Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice. Am J Physiol Heart Circ Physiol (2009) 2.00
NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries. Circ Res (2005) 1.65
Angiotensin II type 2 receptor stimulation initiated after stroke causes neuroprotection in conscious rats. Hypertension (2012) 1.61
Targeting Rho and Rho-kinase in the treatment of cardiovascular disease. Trends Pharmacol Sci (2005) 1.60
NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition. Pharmacol Ther (2008) 1.58
Pathophysiology, treatment, and animal and cellular models of human ischemic stroke. Mol Neurodegener (2011) 1.48
Evidence for a detrimental role of TLR8 in ischemic stroke. Exp Neurol (2013) 1.46
Mechanisms contributing to cerebral infarct size after stroke: gender, reperfusion, T lymphocytes, and Nox2-derived superoxide. J Cereb Blood Flow Metab (2010) 1.36
Oxidative stress and endothelial dysfunction in cerebrovascular disease. Front Biosci (Landmark Ed) (2011) 1.34
Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries. Am J Physiol Heart Circ Physiol (2010) 1.29
Adiponectin receptor signalling in the brain. Br J Pharmacol (2012) 1.28
Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus. Nat Med (2012) 1.23
Importance of T lymphocytes in brain injury, immunodeficiency, and recovery after cerebral ischemia. J Cereb Blood Flow Metab (2012) 1.22
NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival. Naunyn Schmiedebergs Arch Pharmacol (2009) 1.15
Effect of gender on NADPH-oxidase activity, expression, and function in the cerebral circulation: role of estrogen. Stroke (2007) 1.13
Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo. Stroke (2004) 1.11
NADPH oxidase activity is higher in cerebral versus systemic arteries of four animal species: role of Nox2. Am J Physiol Heart Circ Physiol (2008) 1.10
Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke. Mol Pharmacol (2011) 1.04
Effect of gender and sex hormones on vascular oxidative stress. Clin Exp Pharmacol Physiol (2007) 1.02
NADPH oxidases as regulators of tumor angiogenesis: current and emerging concepts. Antioxid Redox Signal (2012) 1.02
Flow-induced cerebral vasodilatation in vivo involves activation of phosphatidylinositol-3 kinase, NADPH-oxidase, and nitric oxide synthase. J Cereb Blood Flow Metab (2006) 1.02
Evidence that nitric oxide inhibits vascular inflammation and superoxide production via a p47phox-dependent mechanism in mice. Clin Exp Pharmacol Physiol (2009) 1.01
Chemokine-related gene expression in the brain following ischemic stroke: no role for CXCR2 in outcome. Brain Res (2010) 1.00
Inwardly rectifying potassium channels in the regulation of vascular tone. Curr Drug Targets (2003) 1.00
Novel isoforms of NADPH-oxidase in cerebral vascular control. Pharmacol Ther (2006) 0.99
Reactive oxygen species in the cerebral circulation: are they all bad? Antioxid Redox Signal (2006) 0.99
NADPH-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke. Brain Res (2006) 0.98
Endothelial cell mineralocorticoid receptors regulate deoxycorticosterone/salt-mediated cardiac remodeling and vascular reactivity but not blood pressure. Hypertension (2014) 0.97
Role of Nox isoforms in angiotensin II-induced oxidative stress and endothelial dysfunction in brain. J Appl Physiol (1985) (2012) 0.97
Nox isoforms in vascular pathophysiology: insights from transgenic and knockout mouse models. Redox Rep (2010) 0.97
Gender influences cerebral vascular responses to angiotensin II through Nox2-derived reactive oxygen species. Stroke (2009) 0.97
Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke. Brain Res (2009) 0.97
Evidence that estrogen suppresses rho-kinase function in the cerebral circulation in vivo. Stroke (2004) 0.96
Vasorelaxant and antioxidant activity of the isoflavone metabolite equol in carotid and cerebral arteries. Brain Res (2007) 0.95
Segmental differences in the roles of rho-kinase and protein kinase C in mediating vasoconstriction. J Pharmacol Exp Ther (2006) 0.95
Augmented superoxide production by Nox2-containing NADPH oxidase causes cerebral artery dysfunction during hypercholesterolemia. Stroke (2010) 0.94
Nox2 oxidase activity accounts for the oxidative stress and vasomotor dysfunction in mouse cerebral arteries following ischemic stroke. PLoS One (2011) 0.94
Pathogenesis of acute stroke and the role of inflammasomes. Ageing Res Rev (2013) 0.94
Reversal of vascular macrophage accumulation and hypertension by a CCR2 antagonist in deoxycorticosterone/salt-treated mice. Hypertension (2012) 0.93
Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice. Am J Physiol Regul Integr Comp Physiol (2004) 0.92
Cerebral vascular effects of reactive oxygen species: recent evidence for a role of NADPH-oxidase. Clin Exp Pharmacol Physiol (2003) 0.92
Isoflavones, equol and cardiovascular disease: pharmacological and therapeutic insights. Curr Med Chem (2007) 0.91
Post-stroke inflammation and the potential efficacy of novel stem cell therapies: focus on amnion epithelial cells. Front Cell Neurosci (2013) 0.91
NADPH-induced contractions of mouse aorta do not involve NADPH oxidase: a role for P2X receptors. J Pharmacol Exp Ther (2006) 0.90
Nitroxyl (HNO) as a vasoprotective signaling molecule. Antioxid Redox Signal (2010) 0.90
Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways. J Neurochem (2012) 0.89
Vascular cognitive impairment and Alzheimer's disease: role of cerebral hypoperfusion and oxidative stress. Naunyn Schmiedebergs Arch Pharmacol (2012) 0.89
Evidence that the EphA2 receptor exacerbates ischemic brain injury. PLoS One (2013) 0.89
Sex-dependent effects of G protein-coupled estrogen receptor activity on outcome after ischemic stroke. Stroke (2014) 0.88
Vascular dysfunction in cerebrovascular disease: mechanisms and therapeutic intervention. Clin Sci (Lond) (2010) 0.88
A flow cytometric method for the analysis of macrophages in the vascular wall. J Immunol Methods (2013) 0.86
Inhibitory effects of protein kinase C on inwardly rectifying K+- and ATP-sensitive K+ channel-mediated responses of the basilar artery. Stroke (2002) 0.86
Reactive oxygen species in the cerebral circulation: physiological roles and therapeutic implications for hypertension and stroke. Drugs (2004) 0.84
Stroke increases g protein-coupled estrogen receptor expression in the brain of male but not female mice. Neurosignals (2012) 0.83
Brain infarct volume after permanent focal ischemia is not dependent on Nox2 expression. Brain Res (2012) 0.83
Opposing roles of endothelial and smooth muscle phosphatidylinositol 3-kinase in vasoconstriction: effects of rho-kinase and hypertension. J Pharmacol Exp Ther (2005) 0.82
Chronic aldosterone administration causes Nox2-mediated increases in reactive oxygen species production and endothelial dysfunction in the cerebral circulation. J Hypertens (2014) 0.82
Vasorelaxant and antiaggregatory actions of the nitroxyl donor isopropylamine NONOate are maintained in hypercholesterolemia. Am J Physiol Heart Circ Physiol (2011) 0.81
Aldosterone and the mineralocorticoid receptor in the cerebral circulation and stroke. Exp Transl Stroke Med (2012) 0.81
Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress. PLoS One (2013) 0.81
Influence of gender on K+-induced cerebral vasodilatation. Stroke (2004) 0.80
Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain. Ann Neurol (2015) 0.80
Vascular rho kinases and their potential therapeutic applications. Curr Opin Drug Discov Devel (2007) 0.79
Ghrelin-related peptides exert protective effects in the cerebral circulation of male mice through a nonclassical ghrelin receptor(s). Endocrinology (2015) 0.79
Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.78
NOX2β: A novel splice variant of NOX2 that regulates NADPH oxidase activity in macrophages. PLoS One (2012) 0.78
The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.78
Nitroxyl (HNO) suppresses vascular Nox2 oxidase activity. Free Radic Biol Med (2013) 0.77
Calsenilin contributes to neuronal cell death in ischemic stroke. Brain Pathol (2012) 0.77
Chlamydia pneumoniae induces a pro-inflammatory phenotype in murine vascular smooth muscle cells independently of elevating reactive oxygen species. Clin Exp Pharmacol Physiol (2012) 0.77
Over-expression of DSCR1 protects against post-ischemic neuronal injury. PLoS One (2012) 0.77
Neurogenic atherosclerosis mediated by neuropeptide y: hardening of the evidence. Arterioscler Thromb Vasc Biol (2003) 0.76
Signalling pathways activated by hydrogen peroxide in vascular smooth muscle. J Hypertens (2005) 0.76
Neuronal NO mediates cerebral vasodilator responses to K+ in hypertensive rats. Hypertension (2002) 0.76
Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP-binding cassette transporter A1. Naunyn Schmiedebergs Arch Pharmacol (2013) 0.76
Reduced cerebrovascular remodeling and functional impairment in spontaneously hypertensive rats following combined treatment with suboptimal doses of telmisartan and ramipril: is less really more? J Hypertens (2010) 0.75
Radicals spark interest in cerebral vasodilator mechanisms. Focus on "TNF-alpha dilates cerebral arteries via NAD(P)H oxidase-dependent Ca2+ spark activation". Am J Physiol Cell Physiol (2006) 0.75
Angiotensin (1-7) as a therapy to prevent rupture of intracranial aneurysms? Hypertension (2014) 0.75
Maternal nicotine exposure and fetal programming of vascular oxidative stress in adult offspring. Br J Pharmacol (2011) 0.75
Corrigendum: Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus. Nat Med (2016) 0.75