Published in Brain Res on January 08, 2007
Equol: pharmacokinetics and biological actions. J Nutr (2010) 1.25
Estrogen receptor agonists for attenuation of neuroinflammation and neurodegeneration. Brain Res Bull (2014) 1.01
Vascular effects of phytoestrogens and alternative menopausal hormone therapy in cardiovascular disease. Mini Rev Med Chem (2012) 0.99
Does equol production determine soy endocrine effects? Eur J Nutr (2012) 0.87
The soybean isoflavonoid equol blocks ritonavir-induced endothelial dysfunction in porcine pulmonary arteries and human pulmonary artery endothelial cells. J Nutr (2009) 0.84
Effect of high soy diet on the cerebrovasculature and endothelial nitric oxide synthase in the ovariectomized rat. Vascul Pharmacol (2010) 0.81
Estrogen receptor and PI3K/Akt signaling pathway involvement in S-(-)equol-induced activation of Nrf2/ARE in endothelial cells. PLoS One (2013) 0.79
Interaction of Isoflavones and Endophyte-Infected Tall Fescue Seed Extract on Vasoactivity of Bovine Mesenteric Vasculature. Front Nutr (2015) 0.79
The Effect of Eqoul, a Metabolite of Isoflavone, on Endothelial Cell-independent Vasodilatation of Human Uterine Artery In Vitro. J Bone Metab (2015) 0.77
The Effects of Steroid Implant and Dietary Soybean Hulls on Estrogenic Activity of Sera of Steers Grazing Toxic Endophyte-Infected Tall Fescue Pasture. Front Vet Sci (2015) 0.77
Acute benefits of the microbial-derived isoflavone metabolite equol on arterial stiffness in men prospectively recruited according to equol producer phenotype: a double-blind randomized controlled trial. Am J Clin Nutr (2016) 0.76
Dietary soy may not confound acute experimental stroke infarct volume outcomes in ovariectomized female rats. Lab Anim (2010) 0.75
Research protocol: effect of natural S-equol on blood pressure and vascular function- a six-month randomized controlled trial among equol non-producers of postmenopausal women with prehypertension or untreated stage 1 hypertension. BMC Complement Altern Med (2016) 0.75
Effect of isoflavones on cardiovascular health: low but not out either. J Clin Biochem Nutr (2008) 0.75
Apoptotic mechanisms after cerebral ischemia. Stroke (2009) 3.92
Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat Rev Drug Discov (2011) 3.08
Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice. Am J Physiol Heart Circ Physiol (2009) 2.00
NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries. Circ Res (2005) 1.65
Angiotensin II type 2 receptor stimulation initiated after stroke causes neuroprotection in conscious rats. Hypertension (2012) 1.61
Targeting Rho and Rho-kinase in the treatment of cardiovascular disease. Trends Pharmacol Sci (2005) 1.60
NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition. Pharmacol Ther (2008) 1.58
Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening. Mol Pharmacol (2010) 1.49
Pathophysiology, treatment, and animal and cellular models of human ischemic stroke. Mol Neurodegener (2011) 1.48
Evidence for a detrimental role of TLR8 in ischemic stroke. Exp Neurol (2013) 1.46
Mechanisms contributing to cerebral infarct size after stroke: gender, reperfusion, T lymphocytes, and Nox2-derived superoxide. J Cereb Blood Flow Metab (2010) 1.36
Oxidative stress and endothelial dysfunction in cerebrovascular disease. Front Biosci (Landmark Ed) (2011) 1.34
Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries. Am J Physiol Heart Circ Physiol (2010) 1.29
Adiponectin receptor signalling in the brain. Br J Pharmacol (2012) 1.28
Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus. Nat Med (2012) 1.23
Importance of T lymphocytes in brain injury, immunodeficiency, and recovery after cerebral ischemia. J Cereb Blood Flow Metab (2012) 1.22
NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival. Naunyn Schmiedebergs Arch Pharmacol (2009) 1.15
Effect of gender on NADPH-oxidase activity, expression, and function in the cerebral circulation: role of estrogen. Stroke (2007) 1.13
Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo. Stroke (2004) 1.11
NADPH oxidase activity is higher in cerebral versus systemic arteries of four animal species: role of Nox2. Am J Physiol Heart Circ Physiol (2008) 1.10
Recent evidence for an involvement of rho-kinase in cerebral vascular disease. Stroke (2006) 1.08
Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke. Mol Pharmacol (2011) 1.04
Effect of gender and sex hormones on vascular oxidative stress. Clin Exp Pharmacol Physiol (2007) 1.02
NADPH oxidases as regulators of tumor angiogenesis: current and emerging concepts. Antioxid Redox Signal (2012) 1.02
Flow-induced cerebral vasodilatation in vivo involves activation of phosphatidylinositol-3 kinase, NADPH-oxidase, and nitric oxide synthase. J Cereb Blood Flow Metab (2006) 1.02
Evidence that nitric oxide inhibits vascular inflammation and superoxide production via a p47phox-dependent mechanism in mice. Clin Exp Pharmacol Physiol (2009) 1.01
Chemokine-related gene expression in the brain following ischemic stroke: no role for CXCR2 in outcome. Brain Res (2010) 1.00
Inwardly rectifying potassium channels in the regulation of vascular tone. Curr Drug Targets (2003) 1.00
Novel isoforms of NADPH-oxidase in cerebral vascular control. Pharmacol Ther (2006) 0.99
The red wine antioxidant resveratrol prevents cardiomyocyte injury following ischemia-reperfusion via multiple sites and mechanisms. Antioxid Redox Signal (2007) 0.99
Reactive oxygen species in the cerebral circulation: are they all bad? Antioxid Redox Signal (2006) 0.99
NADPH-oxidase activity is elevated in penumbral and non-ischemic cerebral arteries following stroke. Brain Res (2006) 0.98
Endothelial cell mineralocorticoid receptors regulate deoxycorticosterone/salt-mediated cardiac remodeling and vascular reactivity but not blood pressure. Hypertension (2014) 0.97
Role of Nox isoforms in angiotensin II-induced oxidative stress and endothelial dysfunction in brain. J Appl Physiol (1985) (2012) 0.97
Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke. Brain Res (2009) 0.97
Gender influences cerebral vascular responses to angiotensin II through Nox2-derived reactive oxygen species. Stroke (2009) 0.97
Understanding the cardioprotective effects of flavonols: discovery of relaxant flavonols without antioxidant activity. J Med Chem (2008) 0.97
Nox isoforms in vascular pathophysiology: insights from transgenic and knockout mouse models. Redox Rep (2010) 0.97
Evidence that estrogen suppresses rho-kinase function in the cerebral circulation in vivo. Stroke (2004) 0.96
High-fructose diet elevates myocardial superoxide generation in mice in the absence of cardiac hypertrophy. Nutrition (2009) 0.96
Segmental differences in the roles of rho-kinase and protein kinase C in mediating vasoconstriction. J Pharmacol Exp Ther (2006) 0.95
Pathogenesis of acute stroke and the role of inflammasomes. Ageing Res Rev (2013) 0.94
Augmented superoxide production by Nox2-containing NADPH oxidase causes cerebral artery dysfunction during hypercholesterolemia. Stroke (2010) 0.94
Nox2 oxidase activity accounts for the oxidative stress and vasomotor dysfunction in mouse cerebral arteries following ischemic stroke. PLoS One (2011) 0.94
Reversal of vascular macrophage accumulation and hypertension by a CCR2 antagonist in deoxycorticosterone/salt-treated mice. Hypertension (2012) 0.93
Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice. Am J Physiol Regul Integr Comp Physiol (2004) 0.92
Cerebral vascular effects of reactive oxygen species: recent evidence for a role of NADPH-oxidase. Clin Exp Pharmacol Physiol (2003) 0.92
Isoflavones, equol and cardiovascular disease: pharmacological and therapeutic insights. Curr Med Chem (2007) 0.91
Antioxidant actions contribute to the antihypertrophic effects of atrial natriuretic peptide in neonatal rat cardiomyocytes. Cardiovasc Res (2006) 0.91
Post-stroke inflammation and the potential efficacy of novel stem cell therapies: focus on amnion epithelial cells. Front Cell Neurosci (2013) 0.91
NADPH-induced contractions of mouse aorta do not involve NADPH oxidase: a role for P2X receptors. J Pharmacol Exp Ther (2006) 0.90
Nitroxyl (HNO) as a vasoprotective signaling molecule. Antioxid Redox Signal (2010) 0.90
Vascular cognitive impairment and Alzheimer's disease: role of cerebral hypoperfusion and oxidative stress. Naunyn Schmiedebergs Arch Pharmacol (2012) 0.89
Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways. J Neurochem (2012) 0.89
Evidence that the EphA2 receptor exacerbates ischemic brain injury. PLoS One (2013) 0.89
Type 1 diabetes and hypercholesterolaemia reveal the contribution of endothelium-derived hyperpolarizing factor to endothelium-dependent relaxation of the rat aorta. Clin Exp Pharmacol Physiol (2007) 0.89
Cardioprotective action of CRF peptide urocortin against simulated ischemia in adult rat cardiomyocytes. Am J Physiol Heart Circ Physiol (2002) 0.88
Sex-dependent effects of G protein-coupled estrogen receptor activity on outcome after ischemic stroke. Stroke (2014) 0.88
Modulation of the glucagon-like peptide-1 receptor signaling by naturally occurring and synthetic flavonoids. J Pharmacol Exp Ther (2010) 0.88
Vascular dysfunction in cerebrovascular disease: mechanisms and therapeutic intervention. Clin Sci (Lond) (2010) 0.88
3',4'-Dihydroxyflavonol restores endothelium-dependent relaxation in small mesenteric artery from rats with type 1 and type 2 diabetes. Eur J Pharmacol (2011) 0.86
A flow cytometric method for the analysis of macrophages in the vascular wall. J Immunol Methods (2013) 0.86
Inhibitory effects of protein kinase C on inwardly rectifying K+- and ATP-sensitive K+ channel-mediated responses of the basilar artery. Stroke (2002) 0.86
3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries. PLoS One (2011) 0.86
Using behaviour to predict stroke severity in conscious rats: post-stroke treatment with 3', 4'-dihydroxyflavonol improves recovery. Eur J Pharmacol (2008) 0.85
Effect of short-term phytoestrogen treatment in male rats on nitric oxide-mediated responses of carotid and cerebral arteries: comparison with 17beta-estradiol. J Pharmacol Exp Ther (2004) 0.85
Reactive oxygen species in the cerebral circulation: physiological roles and therapeutic implications for hypertension and stroke. Drugs (2004) 0.84
Cardioprotection from ischaemia-reperfusion injury by a novel flavonol that reduces activation of p38 MAPK. Eur J Pharmacol (2011) 0.84
3',4'-Dihydroxyflavonol reduces infarct size and injury associated with myocardial ischaemia and reperfusion in sheep. Br J Pharmacol (2004) 0.84
Annexin-1 peptide Anx-1(2-26) protects adult rat cardiac myocytes from cellular injury induced by simulated ischaemia. Br J Pharmacol (2005) 0.84
Brain infarct volume after permanent focal ischemia is not dependent on Nox2 expression. Brain Res (2012) 0.83
Stroke increases g protein-coupled estrogen receptor expression in the brain of male but not female mice. Neurosignals (2012) 0.83
Sodium nitroprusside protects adult rat cardiac myocytes from cellular injury induced by simulated ischemia: role for a non-cGMP-dependent mechanism of nitric oxide protection. J Cardiovasc Pharmacol (2006) 0.83
3', 4'-dihydroxyflavonol enhances nitric oxide bioavailability and improves vascular function after ischemia and reperfusion injury in the rat. J Cardiovasc Pharmacol (2003) 0.83
Low intrinsic exercise capacity in rats predisposes to age-dependent cardiac remodeling independent of macrovascular function. Am J Physiol Heart Circ Physiol (2012) 0.82
The ethanolic extract of Kaempferia parviflora reduces ischaemic injury in rat isolated hearts. J Ethnopharmacol (2011) 0.82
Effects of resveratrol and flavonols on cardiovascular function: Physiological mechanisms. Biofactors (2010) 0.82
Chronic aldosterone administration causes Nox2-mediated increases in reactive oxygen species production and endothelial dysfunction in the cerebral circulation. J Hypertens (2014) 0.82
Opposing roles of endothelial and smooth muscle phosphatidylinositol 3-kinase in vasoconstriction: effects of rho-kinase and hypertension. J Pharmacol Exp Ther (2005) 0.82
Antioxidant activity contributes to flavonol cardioprotection during reperfusion of rat hearts. Free Radic Biol Med (2011) 0.82
Vasorelaxant and antiaggregatory actions of the nitroxyl donor isopropylamine NONOate are maintained in hypercholesterolemia. Am J Physiol Heart Circ Physiol (2011) 0.81
Aldosterone and the mineralocorticoid receptor in the cerebral circulation and stroke. Exp Transl Stroke Med (2012) 0.81
Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress. PLoS One (2013) 0.81
Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain. Ann Neurol (2015) 0.80
3',4'-Dihydroxyflavonol antioxidant attenuates diastolic dysfunction and cardiac remodeling in streptozotocin-induced diabetic m(Ren2)27 rats. PLoS One (2011) 0.80
3',4'-Dihydroxyflavonol improves post-ischaemic coronary endothelial function following 7days reperfusion in sheep. Eur J Pharmacol (2009) 0.80
Influence of gender on K+-induced cerebral vasodilatation. Stroke (2004) 0.80
Cardioprotective 3',4'-dihydroxyflavonol attenuation of JNK and p38(MAPK) signalling involves CaMKII inhibition. Biochem J (2013) 0.79
Ghrelin-related peptides exert protective effects in the cerebral circulation of male mice through a nonclassical ghrelin receptor(s). Endocrinology (2015) 0.79
Effect of type 1 diabetes on the production and vasoactivity of hydrogen sulfide in rat middle cerebral arteries. Physiol Rep (2013) 0.79
Vascular rho kinases and their potential therapeutic applications. Curr Opin Drug Discov Devel (2007) 0.79
Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.78
NOX2β: A novel splice variant of NOX2 that regulates NADPH oxidase activity in macrophages. PLoS One (2012) 0.78
The concomitant coronary vasodilator and positive inotropic actions of the nitroxyl donor Angeli's salt in the intact rat heart: contribution of soluble guanylyl cyclase-dependent and -independent mechanisms. Br J Pharmacol (2014) 0.78
The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.78
Chlamydia pneumoniae induces a pro-inflammatory phenotype in murine vascular smooth muscle cells independently of elevating reactive oxygen species. Clin Exp Pharmacol Physiol (2012) 0.77