Published in Curr Opin Microbiol on July 03, 2006
The structural biology of HIV assembly. Curr Opin Struct Biol (2008) 3.71
Cyclophilin A is an essential cofactor for hepatitis C virus infection and the principal mediator of cyclosporine resistance in vitro. J Virol (2008) 2.22
Evolution of a TRIM5-CypA splice isoform in old world monkeys. PLoS Pathog (2008) 2.20
The interferon response inhibits HIV particle production by induction of TRIM22. PLoS Pathog (2008) 2.06
TRIM E3 ligases interfere with early and late stages of the retroviral life cycle. PLoS Pathog (2008) 2.05
Proteasomal degradation of TRIM5alpha during retrovirus restriction. PLoS Pathog (2008) 1.96
Integrase, LEDGF/p75 and HIV replication. Cell Mol Life Sci (2008) 1.50
Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent. Antimicrob Agents Chemother (2008) 1.46
Innate immune sensing of HIV-1 by dendritic cells. Cell Host Microbe (2012) 1.35
Cyclophilin D in mitochondrial pathophysiology. Biochim Biophys Acta (2009) 1.27
Host genes associated with HIV/AIDS: advances in gene discovery. Trends Genet (2010) 1.25
TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity. J Mol Biol (2013) 1.25
Discovery of novel small-molecule HIV-1 replication inhibitors that stabilize capsid complexes. Antimicrob Agents Chemother (2013) 1.18
The mitochondrial permeability transition from yeast to mammals. FEBS Lett (2010) 1.17
The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects in Col6a1-/- myopathic mice. Br J Pharmacol (2009) 1.16
Cell factors stimulate human immunodeficiency virus type 1 reverse transcription in vitro. J Virol (2007) 1.14
Regulatory polymorphisms in the cyclophilin A gene, PPIA, accelerate progression to AIDS. PLoS Pathog (2007) 1.08
Role of human immunodeficiency virus type 1 integrase in uncoating of the viral core. J Virol (2010) 1.07
Human cytosolic extracts stabilize the HIV-1 core. J Virol (2013) 1.03
Relief of preintegration inhibition and characterization of additional blocks for HIV replication in primary mouse T cells. PLoS One (2008) 1.01
Coupling genetics and proteomics to identify aphid proteins associated with vector-specific transmission of polerovirus (luteoviridae). J Virol (2007) 0.96
Gene expression analyses in Atlantic salmon challenged with infectious salmon anemia virus reveal differences between individuals with early, intermediate and late mortality. BMC Genomics (2008) 0.96
Hepatitis B virus (HBV) surface antigen interacts with and promotes cyclophilin a secretion: possible link to pathogenesis of HBV infection. J Virol (2010) 0.94
Relative contribution of free-virus and synaptic transmission to the spread of HIV-1 through target cell populations. Biol Lett (2012) 0.93
PDZD8 is a novel Gag-interacting factor that promotes retroviral infection. J Virol (2010) 0.91
A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection. PLoS Pathog (2014) 0.88
Unraveling the convoluted biological roles of type I interferons in infection and immunity: a way forward for therapeutics and vaccine design. Front Immunol (2014) 0.87
Identification of an arsenic-sensitive block to primate lentiviral infection of human dendritic cells. J Virol (2007) 0.87
Cyclophilin and viruses: cyclophilin as a cofactor for viral infection and possible anti-viral target. Drug Target Insights (2007) 0.86
Cyclophilin A is required for efficient human cytomegalovirus DNA replication and reactivation. J Gen Virol (2012) 0.85
Keep on moving: discovering and perturbing the conformational dynamics of enzymes. Acc Chem Res (2014) 0.85
Effect of synaptic transmission on viral fitness in HIV infection. PLoS One (2012) 0.84
Homology-based identification of capsid determinants that protect HIV1 from human TRIM5α restriction. J Biol Chem (2010) 0.84
The TPR domain in the host Cyp40-like cyclophilin binds to the viral replication protein and inhibits the assembly of the tombusviral replicase. PLoS Pathog (2012) 0.84
Requirements for peptidyl-prolyl isomerization activity: a comprehensive mutational analysis of the substrate-binding cavity of FK506-binding protein 12. Protein Sci (2007) 0.83
Retroviral restriction and dependency factors in primates and carnivores. Vet Immunol Immunopathol (2011) 0.83
Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity. Cell Rep (2015) 0.82
Nuclear Envelope Protein SUN2 Promotes Cyclophilin-A-Dependent Steps of HIV Replication. Cell Rep (2016) 0.80
SUN2 silencing impairs CD4 T cell proliferation and alters sensitivity to HIV-1 infection independently of Cyclophilin A. J Virol (2017) 0.78
Cyclosporin a and rapamycin relieve distinct lentiviral restriction blocks in hematopoietic stem and progenitor cells. Mol Ther (2014) 0.78
Interaction of cyclophilin A with a novel binding protein, SR-25, and characterization of their expression pattern in Chinese hepatocellular carcinoma patients. Oncol Lett (2016) 0.75
Association of Polymorphisms in the Regulatory Region of the Cyclophilin a Gene (PPIA) with Gene Expression and HIV/AIDS Disease Progression. J Acquir Immune Defic Syndr (2016) 0.75
Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1. Nature (2004) 7.10
TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature (2011) 6.29
Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors. Nat Med (2003) 5.97
TRIM5alpha selectively binds a restriction-sensitive retroviral capsid. Retrovirology (2005) 3.39
TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs. J Clin Invest (2005) 3.04
HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation. PLoS Pathog (2009) 2.92
Target cell cyclophilin A modulates human immunodeficiency virus type 1 infectivity. J Virol (2004) 2.51
Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells. J Virol (2008) 2.41
Cyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cells. Proc Natl Acad Sci U S A (2005) 2.21
Envelope-dependent, cyclophilin-independent effects of glycosaminoglycans on human immunodeficiency virus type 1 attachment and infection. J Virol (2002) 2.11
Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics. PLoS Pathog (2009) 1.94
As(2)O(3) enhances retroviral reverse transcription and counteracts Ref1 antiviral activity. J Virol (2003) 1.94
Human cellular restriction factors that target HIV-1 replication. BMC Med (2009) 1.86
Cyclophilin A and TRIM5alpha independently regulate human immunodeficiency virus type 1 infectivity in human cells. J Virol (2006) 1.77
Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components. J Clin Invest (2009) 1.73
AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis. Oncogene (2004) 1.68
Lv1 inhibition of human immunodeficiency virus type 1 is counteracted by factors that stimulate synthesis or nuclear translocation of viral cDNA. J Virol (2004) 1.56
Blockade of late stages of autoimmune diabetes by inhibition of the receptor for advanced glycation end products. J Immunol (2004) 1.55
Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk. Immunity (2004) 1.50
Specific incorporation of heat shock protein 70 family members into primate lentiviral virions. J Virol (2002) 1.50
Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia. J Exp Med (2007) 1.50
Disruption of human TRIM5alpha antiviral activity by nonhuman primate orthologues. J Virol (2005) 1.49
TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. J Virol (2012) 1.47
A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal. J Biol Chem (2008) 1.38
TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm. Retrovirology (2013) 1.38
Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus. Retrovirology (2011) 1.32
Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon. Retrovirology (2011) 1.32
HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency. Retrovirology (2012) 1.27
TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-kappaB-responsive long terminal repeat elements. J Virol (2011) 1.16
Selection for loss of Ref1 activity in human cells releases human immunodeficiency virus type 1 from cyclophilin A dependence during infection. J Virol (2004) 1.14
TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling. Curr Opin Virol (2012) 1.12
Covalent modification of human immunodeficiency virus type 1 p6 by SUMO-1. J Virol (2005) 1.11
ATPgammaS disrupts human immunodeficiency virus type 1 virion core integrity. J Virol (2005) 1.08
p62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha. J Virol (2010) 1.08
Cyclophilin A-deficient mice are resistant to immunosuppression by cyclosporine. J Immunol (2005) 1.07
Deciphering the code for retroviral integration target site selection. PLoS Comput Biol (2010) 1.06
Cyclophilin A peptidyl-prolyl isomerase activity promotes ZPR1 nuclear export. Mol Cell Biol (2002) 1.05
Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression. J Biol Chem (2003) 1.05
Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay. Retrovirology (2013) 1.03
Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1. Proc Natl Acad Sci U S A (2009) 1.02
Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection. J Virol (2010) 1.02
Arsenic counteracts human immunodeficiency virus type 1 restriction by various TRIM5 orthologues in a cell type-dependent manner. J Virol (2006) 1.01
The role of lysine 186 in HIV-1 integrase multimerization. Virology (2007) 1.00
An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding. J Virol (2009) 0.98
Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41. PLoS Pathog (2011) 0.98
TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions. Retrovirology (2011) 0.97
HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes. Mol Biol Cell (2004) 0.96
Production of ribosome components in effector CD4+ T cells is accelerated by TCR stimulation and coordinated by ERK-MAPK. Immunity (2003) 0.96
Overcoming current limitations in humanized mouse research. J Infect Dis (2013) 0.95
The double-stranded RNA binding domain of the vaccinia virus E3L protein inhibits both RNA- and DNA-induced activation of interferon beta. J Biol Chem (2009) 0.93
Lentiviral vector gene transfer is limited by the proteasome at postentry steps in various types of stem cells. Stem Cells (2008) 0.93
The fate of HIV-1 capsid: a biochemical assay for HIV-1 uncoating. Methods Mol Biol (2014) 0.93
Cyclosporine A-sensitive, cyclophilin B-dependent endoplasmic reticulum-associated degradation. PLoS One (2010) 0.92
Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells. J Virol (2007) 0.91
Processing strategies and software solutions for data-independent acquisition in mass spectrometry. Proteomics (2015) 0.89
The retroviral restriction factor TRIM5alpha. Curr Infect Dis Rep (2007) 0.87
G2 cell cycle arrest and cyclophilin A in lentiviral gene transfer. Mol Ther (2006) 0.84
Cyclosporine blocks incorporation of HIV-1 envelope glycoprotein into virions. J Virol (2010) 0.82
The carboxyl-terminus of human immunodeficiency virus type 2 circulating recombinant form 01_AB capsid protein affects sensitivity to human TRIM5α. PLoS One (2012) 0.82
Cyclophilin B interacts with sodium-potassium ATPase and is required for pump activity in proximal tubule cells of the kidney. PLoS One (2010) 0.80
TRIM5α and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment. J Virol (2014) 0.78
Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness. medRxiv (2022) 0.75