Published in J Mol Biol on December 12, 2013
Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response. Immunity (2014) 1.01
TRIM32 Senses and Restricts Influenza A Virus by Ubiquitination of PB1 Polymerase. PLoS Pathog (2015) 0.98
Ubiquitination in the antiviral immune response. Virology (2015) 0.92
The E3 ubiquitin ligase tripartite motif 33 is essential for cytosolic RNA-induced NLRP3 inflammasome activation. J Immunol (2014) 0.91
Crystal structure of cytomegalovirus IE1 protein reveals targeting of TRIM family member PML via coiled-coil interactions. PLoS Pathog (2014) 0.91
A Bacterial Pathogen Targets a Host Rab-Family GTPase Defense Pathway with a GAP. Cell Host Microbe (2016) 0.87
Proteomic analysis of ubiquitin-like posttranslational modifications induced by the adenovirus E4-ORF3 protein. J Virol (2014) 0.84
Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation. Immunity (2015) 0.84
Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity. EMBO J (2016) 0.83
Overlapping and distinct molecular determinants dictating the antiviral activities of TRIM56 against flaviviruses and coronavirus. J Virol (2014) 0.82
PML/TRIM19-Dependent Inhibition of Retroviral Reverse-Transcription by Daxx. PLoS Pathog (2015) 0.82
TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity. Immunol Rev (2015) 0.81
Modulation of Immune Cell Functions by the E3 Ligase Cbl-b. Front Oncol (2015) 0.81
The Salmonella Effector Protein SopA Modulates Innate Immune Responses by Targeting TRIM E3 Ligase Family Members. PLoS Pathog (2016) 0.79
The C-Terminal Tail of TRIM56 Dictates Antiviral Restriction of Influenza A and B Viruses by Impeding Viral RNA Synthesis. J Virol (2016) 0.79
The ubiquitin-conjugating system: multiple roles in viral replication and infection. Cells (2014) 0.79
Trim65: a cofactor for regulation of the microRNA pathway. RNA Biol (2014) 0.79
The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response. PLoS Pathog (2016) 0.79
TRIM9 short isoform preferentially promotes DNA and RNA virus-induced production of type I interferon by recruiting GSK3β to TBK1. Cell Res (2016) 0.78
Trim9 Deletion Alters the Morphogenesis of Developing and Adult-Born Hippocampal Neurons and Impairs Spatial Learning and Memory. J Neurosci (2016) 0.77
TRIM52 inhibits Japanese Encephalitis Virus replication by degrading the viral NS2A. Sci Rep (2016) 0.77
The host E3-Ubiquitin ligase TRIM6 ubiquitinates the Ebola virus VP35 protein and promotes virus replication. J Virol (2017) 0.75
Trim32 Deficiency Enhances Th2 Immunity and Predisposes to Features of Atopic Dermatitis. J Invest Dermatol (2016) 0.75
Ubiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global Profiling. Front Immunol (2015) 0.75
TRIM25 Identification in the Chinese Goose: Gene Structure, Tissue Expression Profiles, and Antiviral Immune Responses In Vivo and In Vitro. Biomed Res Int (2016) 0.75
Single point mutations in the helicase domain of the NS3 protein enhance dengue virus replicative capacity in human monocyte-derived dendritic cells and circumvent the type I interferon response. Clin Exp Immunol (2015) 0.75
Manipulation of the innate immune response by human papillomaviruses. Virus Res (2016) 0.75
Delicate coordination of TRIM21's dual activity in virus neutralization and signaling. Proc Natl Acad Sci U S A (2015) 0.75
Positive selection of the TRIM family regulatory region in primate genomes. Proc Biol Sci (2016) 0.75
Cell-Based Screen Identifies Human Interferon-Stimulated Regulators of Listeria monocytogenes Infection. PLoS Pathog (2016) 0.75
Unreported intrinsic disorder in proteins: Building connections to the literature on IDPs. Intrinsically Disord Proteins (2014) 0.75
Expression profiling of TRIM protein family in THP1-derived macrophages following TLR stimulation. Sci Rep (2017) 0.75
TRIM25 in the Regulation of the Antiviral Innate Immunity. Front Immunol (2017) 0.75
TRIM29 promotes DNA virus infections by inhibiting innate immune response. Nat Commun (2017) 0.75
The Transcriptional Changes of trim Genes Associated with Parkinson's Disease on a Model of Human Induced Pluripotent Stem Cells. Mol Neurobiol (2016) 0.75
The TRIMendous Role of TRIMs in Virus-Host Interactions. Vaccines (Basel) (2017) 0.75
Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Inflammatory Cytokine Production and Promotes Invasiveness. J Biol Chem (2017) 0.75
FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection. Front Immunol (2017) 0.75
Solution NMR structure of the TRIM21 B-box2 and identification of residues involved in its interaction with the RING domain. PLoS One (2017) 0.75
Antagonism of type I interferon by flaviviruses. Biochem Biophys Res Commun (2017) 0.75
Ubiquitin enzymes in the regulation of immune responses. Crit Rev Biochem Mol Biol (2017) 0.75
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Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21. Nat Immunol (2013) 2.42
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