Published in Angew Chem Int Ed Engl on July 24, 2006
Caged compounds: photorelease technology for control of cellular chemistry and physiology. Nat Methods (2007) 3.22
Gold nanocages covered by smart polymers for controlled release with near-infrared light. Nat Mater (2009) 2.85
Illuminating the chemistry of life: design, synthesis, and applications of "caged" and related photoresponsive compounds. ACS Chem Biol (2009) 2.67
Photoremovable protecting groups in chemistry and biology: reaction mechanisms and efficacy. Chem Rev (2012) 2.49
A facile system for encoding unnatural amino acids in mammalian cells. Angew Chem Int Ed Engl (2009) 2.02
Selective labeling of living cells by a photo-triggered click reaction. J Am Chem Soc (2009) 1.89
Polymeric micelles in anticancer therapy: targeting, imaging and triggered release. Pharm Res (2010) 1.83
Subcellular control of Rac-GTPase signalling by magnetogenetic manipulation inside living cells. Nat Nanotechnol (2013) 1.82
Photoregulated release of caged anticancer drugs from gold nanoparticles. J Am Chem Soc (2009) 1.68
A biomolecule-compatible visible-light-induced azide reduction from a DNA-encoded reaction-discovery system. Nat Chem (2011) 1.54
Gold nanoparticle platforms as drug and biomacromolecule delivery systems. J Control Release (2010) 1.54
Optogenetic control of cells and circuits. Annu Rev Cell Dev Biol (2011) 1.40
Tuning photochromic ion channel blockers. ACS Chem Neurosci (2011) 1.39
Recent advances in the photochemical control of protein function. Trends Biotechnol (2010) 1.32
Light-dependent RNA interference with nucleobase-caged siRNAs. RNA (2007) 1.31
Photochemical DNA activation. Org Lett (2007) 1.25
Light activation as a method of regulating and studying gene expression. Curr Opin Chem Biol (2009) 1.25
Controlling the enzymatic activity of a restriction enzyme by light. Proc Natl Acad Sci U S A (2009) 1.25
Time-resolved structural studies of protein reaction dynamics: a smorgasbord of X-ray approaches. Acta Crystallogr A (2010) 1.23
Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. J Am Chem Soc (2010) 1.23
Subcellular-resolution delivery of a cytokine through precisely manipulated nanowires. Nat Nanotechnol (2010) 1.18
Regulating gene expression in human leukemia cells using light-activated oligodeoxynucleotides. Nucleic Acids Res (2007) 1.17
Direct observation of disulfide isomerization in a single protein. Nat Chem (2011) 1.17
Gold nanorods based platforms for light-mediated theranostics. Theranostics (2013) 1.11
Visualizing metal ions in cells: an overview of analytical techniques, approaches, and probes. Biochim Biophys Acta (2012) 1.10
Activation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cells. J Am Chem Soc (2010) 1.09
Applications of p-hydroxyphenacyl (pHP) and coumarin-4-ylmethyl photoremovable protecting groups. Photochem Photobiol Sci (2012) 1.07
Targeting gold nanocages to cancer cells for photothermal destruction and drug delivery. Expert Opin Drug Deliv (2010) 1.06
Chemical modification of siRNA bases to probe and enhance RNA interference. J Org Chem (2011) 1.06
Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate. Chem Commun (Camb) (2010) 1.04
Light-triggered polymerase chain reaction. Chem Commun (Camb) (2007) 1.04
Optically selective two-photon uncaging of glutamate at 900 nm. J Am Chem Soc (2013) 1.02
Optical control of antibacterial activity. Nat Chem (2013) 1.01
5-Fluoro pyrimidines: labels to probe DNA and RNA secondary structures by 1D 19F NMR spectroscopy. Nucleic Acids Res (2009) 0.99
Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore. J Am Chem Soc (2011) 0.98
RNA bandages for photoregulating in vitro protein synthesis. Bioorg Med Chem Lett (2008) 0.98
Genetically encoded light-activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells. J Am Chem Soc (2013) 0.98
Photoregulated release of noncovalent guests from dendritic amphiphilic nanocontainers. Angew Chem Int Ed Engl (2011) 0.97
Dual wavelength photoactivation of cAMP- and cGMP-dependent protein kinase signaling pathways. ACS Chem Biol (2011) 0.97
In situ assembly of macromolecular complexes triggered by light. Proc Natl Acad Sci U S A (2010) 0.96
Engineering the Properties of Metal Nanostructures via Galvanic Replacement Reactions. Mater Sci Eng R Rep (2010) 0.95
Photocaged t7 RNA polymerase for the light activation of transcription and gene function in pro- and eukaryotic cells. Chembiochem (2010) 0.94
Photochemical control of DNA decoy function enables precise regulation of nuclear factor κB activity. J Am Chem Soc (2011) 0.93
Light-activation of gene function in mammalian cells via ribozymes. Chem Commun (Camb) (2008) 0.92
Caged protein prenyltransferase substrates: tools for understanding protein prenylation. Chem Biol Drug Des (2008) 0.92
Light-regulated RNA-small molecule interactions. Chembiochem (2008) 0.92
A fast ruthenium polypyridine cage complex photoreleases glutamate with visible or IR light in one and two photon regimes. J Inorg Biochem (2009) 0.91
Regulating enzymatic activity with a photoswitchable affinity label. Chembiochem (2008) 0.91
Light-mediated spatial control via photolabile fluorescently quenched peptide cassettes. J Am Chem Soc (2010) 0.90
Optochemogenetics (OCG) allows more precise control of genetic engineering in mice with CreER regulators. Bioconjug Chem (2012) 0.90
Light-Controlled Histone Deacetylase (HDAC) Inhibitors: Towards Photopharmacological Chemotherapy. Chemistry (2015) 0.90
Photomodulating RNA cleavage using photolabile circular antisense oligodeoxynucleotides. Nucleic Acids Res (2010) 0.89
A chemist and biologist talk to each other about caged neurotransmitters. Beilstein J Org Chem (2013) 0.88
Manipulation of gene expression in zebrafish using caged circular morpholino oligomers. Nucleic Acids Res (2012) 0.88
Visible Light Controlled Release of Anticancer Drug through Double Activation of Prodrug. ACS Med Chem Lett (2012) 0.88
Regulation of transcription through light-activation and light-deactivation of triplex-forming oligonucleotides in mammalian cells. ACS Chem Biol (2012) 0.88
Merging of confocal and caging technologies: selective three-color communication with profluorescent reporters. Angew Chem Int Ed Engl (2012) 0.88
A modified consumer inkjet for spatiotemporal control of gene expression. PLoS One (2009) 0.87
Optochemical control of deoxyoligonucleotide function via a nucleobase-caging approach. Acc Chem Res (2013) 0.87
Dependence of aptamer activity on opposed terminal extensions: improvement of light-regulation efficiency. Nucleic Acids Res (2009) 0.87
Caged ceramide 1-phosphate analogues: synthesis and properties. J Org Chem (2009) 0.86
Spectral evolution of a photochemical protecting group for orthogonal two-color uncaging with visible light. J Am Chem Soc (2013) 0.86
A photochemical approach for controlled drug release in targeted drug delivery. Bioorg Med Chem (2011) 0.85
Photochemical tools to study dynamic biological processes. HFSP J (2009) 0.85
Photochemically initiated intracellular astrocytic calcium waves in living mice using two-photon uncaging of IP(3). ACS Chem Neurosci (2010) 0.85
Photon-regulated DNA-enzymatic nanostructures by molecular assembly. ACS Nano (2011) 0.84
Photocaged permeability: a new strategy for controlled drug release. Chem Commun (Camb) (2012) 0.84
Light-activated gene editing with a photocaged zinc-finger nuclease. Angew Chem Int Ed Engl (2011) 0.83
Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors. Sci Rep (2015) 0.83
Photochemical modulation of Ras-mediated signal transduction using caged farnesyltransferase inhibitors: activation by one- and two-photon excitation. Chembiochem (2012) 0.83
Synthesis of a photocaged tamoxifen for light-dependent activation of Cre-ER recombinase-driven gene modification. Chem Commun (Camb) (2013) 0.83
Triggered Nanoparticles as Therapeutics. Nano Today (2013) 0.83
Light activation of transcription: photocaging of nucleotides for control over RNA polymerization. Nucleic Acids Res (2008) 0.83
Photochemical regulation of restriction endonuclease activity. Chembiochem (2009) 0.82
Acetylcholinesterase inhibitors with photoswitchable inhibition of β-amyloid aggregation. ACS Chem Neurosci (2014) 0.82
Light-triggered disassembly of amyloid fibrils. Langmuir (2012) 0.82
Optochemical control of RNA interference in mammalian cells. Nucleic Acids Res (2013) 0.82
Diarylethene-modified nucleotides for switching optical properties in DNA. Beilstein J Org Chem (2012) 0.81
Bioorthogonal chemical reporter methodology for visualization, isolation and analysis of glycoconjugates. Carbohydr Chem (2010) 0.81
Mismatch Discrimination and Efficient Photomodulation with Split 10-23 DNAzymes. Inorganica Chim Acta (2012) 0.81
Dual imaging and photoactivated nanoprobe for controlled cell tracking. Small (2012) 0.80
Caged agonist of P2Y1 and P2Y12 receptors for light-directed facilitation of platelet aggregation. Biochem Pharmacol (2007) 0.80
Construction of a photoactivatable profluorescent enzyme via propinquity labeling. J Am Chem Soc (2011) 0.80
Caged O-phosphorothioyl amino acids as building blocks for Fmoc-based solid phase peptide synthesis. Tetrahedron (2007) 0.80
Single-stranded DNA as a cleavable linker for bioorthogonal click chemistry-based proteomics. Bioconjug Chem (2013) 0.80
Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization. Nucleic Acids Res (2009) 0.80
Cellular delivery and photochemical activation of antisense agents through a nucleobase caging strategy. ACS Chem Biol (2013) 0.80
Optically Triggered Immune Response through Photocaged Oligonucleotides. Tetrahedron Lett (2015) 0.80
Light control of cellular processes by using photocaged abscisic acid. Chembiochem (2014) 0.80
Tightening up the structure, lighting up the pathway: Application of molecular constraints and light to manipulate protein folding, self-assembly and function. Sci China Chem (2014) 0.80
Light-activated serotonin for exploring its action in biological systems. Chem Biol (2013) 0.79
Improved synthesis of the two-photon caging group 3-nitro-2-ethyldibenzofuran and its application to a caged thymidine phosphoramidite. Org Lett (2010) 0.79
Unraveling the mechanism of the photodeprotection reaction of 8-bromo- and 8-chloro-7-hydroxyquinoline caged acetates. Chemistry (2012) 0.79
Complete optical neurophysiology: toward optical stimulation and recording of neural tissue. Appl Opt (2009) 0.79
Light-mediated remote control of signaling pathways. Biochim Biophys Acta (2009) 0.79
Phototriggerable 2',7-caged paclitaxel. PLoS One (2012) 0.79
Experimental and theoretical investigations in stimuli responsive dendrimer-based assemblies. Nanoscale (2015) 0.79
Development of Anionically Decorated Caged Neurotransmitters: In Vitro Comparison of 7-Nitroindolinyl- and 2-(p-Phenyl-o-nitrophenyl)propyl-Based Photochemical Probes. Chembiochem (2016) 0.78
Photoactive Electrospun Polymeric Meshes: Spatiotemporally Wetting of Textured 3-Dimensional Structures. J Mater Chem B Mater Biol Med (2014) 0.78
Photo-Triggered Click Chemistry for Biological Applications. Top Curr Chem (J) (2015) 0.78
Light-controlled tools. Angew Chem Int Ed Engl (2012) 1.96
Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates. Nucleic Acids Res (2004) 1.84
TADDOLs, Their Derivatives, and TADDOL Analogues: Versatile Chiral Auxiliaries. Angew Chem Int Ed Engl (2001) 1.73
Completion of a Programmable DNA-Binding Small Molecule Library. Tetrahedron (2007) 1.58
Light-dependent RNA interference with nucleobase-caged siRNAs. RNA (2007) 1.31
The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA. Nucleic Acids Res (2010) 1.17
A double-stranded DNA rotaxane. Nat Nanotechnol (2010) 1.16
The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase. Nucleic Acids Res (2010) 1.16
Photoinduced transcription by using temporarily mismatched caged oligonucleotides. Angew Chem Int Ed Engl (2005) 1.13
A ribozyme for the aldol reaction. Chem Biol (2005) 1.00
Light-induced formation of G-quadruplex DNA secondary structures. Chembiochem (2005) 0.99
Construction of a structurally defined double-stranded DNA catenane. Nano Lett (2011) 0.90
Coumarin-caged dG for improved wavelength-selective uncaging of DNA. Org Lett (2011) 0.87
Polyamide struts for DNA architectures. Angew Chem Int Ed Engl (2007) 0.87
Dependence of aptamer activity on opposed terminal extensions: improvement of light-regulation efficiency. Nucleic Acids Res (2009) 0.87
DNA minicircles with gaps for versatile functionalization. Angew Chem Int Ed Engl (2008) 0.85
Probing the limits of liquid droplet laser desorption mass spectrometry in the analysis of oligonucleotides and nucleic acids. Rapid Commun Mass Spectrom (2009) 0.83
Differential regulation of protein subdomain activity with caged bivalent ligands. Chembiochem (2009) 0.83
Wavelength-selective uncaging of dA and dC residues. Org Lett (2011) 0.82
Prion protein amyloid formation involves structural rearrangements in the C-terminal domain. Chembiochem (2010) 0.81
Regulating angiogenesis with light-inducible AntimiRs. Angew Chem Int Ed Engl (2013) 0.80
Structure-activity relationships of a caged thrombin binding DNA aptamer: insight gained from molecular dynamics simulation studies. J Struct Biol (2009) 0.79
Three-dimensional protein networks assembled by two-photon activation. Angew Chem Int Ed Engl (2014) 0.79
Light-activatable molecular beacons with a caged loop sequence. Chem Commun (Camb) (2011) 0.79
Pyrrole/imidazole-polyamide anchors for DNA tertiary interactions. Small (2009) 0.79
Light-inducible molecular beacons for spatio-temporally highly defined activation. Chem Commun (Camb) (2013) 0.78
Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates. Chem Commun (Camb) (2010) 0.78
Caged glucosamine-6-phosphate for the light-control of riboswitch activity. Photochem Photobiol Sci (2011) 0.78
Comparison of the duplex-destabilizing effects of nucleobase-caged oligonucleotides. Anal Bioanal Chem (2010) 0.78
Caged glutathione - triggering protein interaction by light. Angew Chem Int Ed Engl (2012) 0.77
Four levels of wavelength-selective uncaging for oligonucleotides. Org Lett (2013) 0.77
From selection to caged aptamers: identification of light-dependent ssDNA aptamers targeting cytohesin. Bioorg Med Chem Lett (2009) 0.77
DNA minicircles connected via G-quadruplex interaction modules. Small (2010) 0.77
Reversible photoswitching of RNA hybridization at room temperature with an azobenzene C-nucleoside. Chemistry (2014) 0.77
Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs. RNA (2012) 0.77
A light trigger for DNA nanotechnology. Small (2011) 0.76
Functional detection of proteins by caged aptamers. ACS Chem Biol (2011) 0.76
Ultrafast dynamics of a spiropyran in water. J Am Chem Soc (2012) 0.76
A two-photon activatable amino acid linker for the induction of fluorescence. Chem Commun (Camb) (2015) 0.75
Photon cascade with clip-on fluorophores. Chemphyschem (2011) 0.75
Wavelength-selective uncaging of oligonucleotides. Curr Protoc Nucleic Acid Chem (2014) 0.75
Characterization of conformational dynamics of bistable RNA by equilibrium and non-equilibrium NMR. Curr Protoc Nucleic Acid Chem (2014) 0.75
Selective uncaging of DNA through reaction rate selectivity. Org Lett (2014) 0.75
Aptamer-guided caging for selective masking of protein domains. Angew Chem Int Ed Engl (2013) 0.75
Spiropyran photoswitches in the context of DNA: synthesis and photochromic properties. Chemistry (2013) 0.75
Influence of the absolute configuration of npe-caged cytosine on DNA single base pair stability. Angew Chem Int Ed Engl (2013) 0.75
Controlling photochemistry via isotopomers and IR preexcitation. J Am Chem Soc (2017) 0.75
Light-stimulated patterning of cells. Chembiochem (2007) 0.75
Binding of hairpin polyamides to DNA studied by fluorescence correlation spectroscopy for DNA nanoarchitectures. Anal Bioanal Chem (2008) 0.75
Computational design of improved two-photon active caging compounds based on nitrodibenzofuran. J Comput Chem (2012) 0.75