Published in J Am Chem Soc on July 29, 2011
MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice. Nucleic Acids Res (2013) 0.94
Light-controlled synthetic gene circuits. Curr Opin Chem Biol (2012) 0.94
Manipulation of gene expression in zebrafish using caged circular morpholino oligomers. Nucleic Acids Res (2012) 0.88
Optochemical control of deoxyoligonucleotide function via a nucleobase-caging approach. Acc Chem Res (2013) 0.87
Spatiotemporal control of microRNA function using light-activated antagomirs. Mol Biosyst (2012) 0.85
Optochemical control of RNA interference in mammalian cells. Nucleic Acids Res (2013) 0.82
Controlling the origins of inflammation with a photoactive lipopeptide immunopotentiator. Angew Chem Int Ed Engl (2015) 0.81
Cellular delivery and photochemical activation of antisense agents through a nucleobase caging strategy. ACS Chem Biol (2013) 0.80
Optically Triggered Immune Response through Photocaged Oligonucleotides. Tetrahedron Lett (2015) 0.80
Site-specific promoter caging enables optochemical gene activation in cells and animals. J Am Chem Soc (2014) 0.78
Catch and Release DNA Decoys: Capture and Photochemical Dissociation of NF-κB Transcription Factors. ACS Chem Biol (2016) 0.76
Molecular stripping, targets and decoys as modulators of oscillations in the NF-κB/IκBα/DNA genetic network. J R Soc Interface (2016) 0.76
Biologically active molecules with a "light switch". Angew Chem Int Ed Engl (2006) 3.92
Regulation of gene expression with double-stranded phosphorothioate oligonucleotides. Science (1990) 2.33
The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy. Expert Opin Ther Targets (2010) 1.85
Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease. Pharmacol Ther (2008) 1.74
Photochemical control of biological processes. Org Biomol Chem (2006) 1.64
Therapeutic applications of transcription factor decoy oligonucleotides. J Clin Invest (2000) 1.53
NF-κB and innate immunity in ischemic stroke. Ann N Y Acad Sci (2010) 1.34
Principles and applications of the photochemical control of cellular processes. Chembiochem (2010) 1.33
Gene silencing in mammalian cells with light-activated antisense agents. Chembiochem (2008) 1.33
Recent advances in the photochemical control of protein function. Trends Biotechnol (2010) 1.32
Light-dependent RNA interference with nucleobase-caged siRNAs. RNA (2007) 1.31
NF-kappaB regulation: the nuclear response. J Cell Mol Med (2009) 1.27
Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice. BMC Cancer (2007) 1.26
Photochemical DNA activation. Org Lett (2007) 1.25
Light activation as a method of regulating and studying gene expression. Curr Opin Chem Biol (2009) 1.25
Regulating gene expression in human leukemia cells using light-activated oligodeoxynucleotides. Nucleic Acids Res (2007) 1.17
Photocaged morpholino oligomers for the light-regulation of gene function in zebrafish and Xenopus embryos. J Am Chem Soc (2010) 1.16
Photoinduced transcription by using temporarily mismatched caged oligonucleotides. Angew Chem Int Ed Engl (2005) 1.13
Caged siRNAs for spatiotemporal control of gene silencing. Mol Pharm (2009) 1.13
Activation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cells. J Am Chem Soc (2010) 1.09
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. J Immunol (2010) 1.05
Light-triggered polymerase chain reaction. Chem Commun (Camb) (2007) 1.04
Targeted disruption of stat6 DNA binding activity by an oligonucleotide decoy blocks IL-4-driven T(H)2 cell response. Blood (2000) 1.03
Taking control of gene expression with light-activated oligonucleotides. Biotechniques (2007) 1.02
New trends in the development of transcription factor decoy (TFD) pharmacotherapy. Curr Drug Targets (2004) 0.96
Turning the 10-23 DNAzyme on and off with light. Chembiochem (2010) 0.95
Transcription factor decoy for NFkappaB inhibits cytokine and adhesion molecule expressions in synovial cells derived from rheumatoid arthritis. Rheumatology (Oxford) (2000) 0.89
Effect of NF-κB decoy oligodeoxynucleotide on LPS/high-fat diet-induced atherosclerosis in an animal model. Basic Clin Pharmacol Toxicol (2010) 0.88
NFkappaB decoy oligonucleotides. Curr Opin Mol Ther (2010) 0.88
Increase in nuclease resistance and incorporation of NF-kappaB decoy oligodeoxynucleotides by modification of the 3'-terminus. J Gene Med (2007) 0.88
Regulation of NF-kappaB signaling by decoy oligodeoxynucleotides. Microbiol Immunol (2006) 0.87
Sequence-specific inhibition of a transcription factor by circular dumbbell DNA oligonucleotides. FEBS Lett (1999) 0.87
Transcriptional regulation of NF-kappaB by ring type decoy oligodeoxynucleotide in an animal model of nephropathy. Exp Mol Pathol (2008) 0.86
Gene therapy using ets-1 transcription factor decoy for peritoneal dissemination of gastric cancer. Int J Cancer (2007) 0.86
Oligonucleotide decoy to NF-kappaB slowly released from PLGA microspheres reduces chronic inflammation in rat. Pharmacol Res (2009) 0.86
Advantages of the circular dumbbell decoy in gene therapy and studies of gene regulation. Curr Drug Targets (2003) 0.82
Quantification of gene expression with a secreted alkaline phosphatase reporter system. Biotechniques (1997) 0.81
An oligonucleotide decoy for transcription factor E2F inhibits mesangial cell proliferation in vitro. Am J Physiol (1998) 0.80
Antitumor activity of decoy oligodeoxynucleotides targeted to NF-kappaB in vitro and in vivo. Asian Pac J Cancer Prev (2010) 0.80
Targeting cytokine expression in glial cells by cellular delivery of an NF-kappaB decoy. J Mol Neurosci (2007) 0.79
A double-strand decoy DNA oligomer for NF-kappaB inhibits TNFalpha-induced ICAM-1 expression in sinusoidal endothelial cells. Biochem Biophys Res Commun (2002) 0.79
Decoy androgen-responsive element DNA can inhibit androgen receptor transactivation of the PSA promoter gene. Ann Clin Lab Sci (2005) 0.78
Enhancement of ultraviolet-induced apoptosis by NF-kappaB decoy oligonucleotides. Br J Dermatol (2005) 0.78
Light-activated kinases enable temporal dissection of signaling networks in living cells. J Am Chem Soc (2011) 2.22
Genetic encoding and labeling of aliphatic azides and alkynes in recombinant proteins via a pyrrolysyl-tRNA Synthetase/tRNA(CUA) pair and click chemistry. J Am Chem Soc (2009) 2.06
Small-molecule inhibitors of microrna miR-21 function. Angew Chem Int Ed Engl (2008) 2.00
Genetically encoded photocontrol of protein localization in mammalian cells. J Am Chem Soc (2010) 1.94
A genetically encoded fluorescent amino acid. Proc Natl Acad Sci U S A (2006) 1.66
A genetically encoded photocaged amino acid. J Am Chem Soc (2004) 1.65
Photochemical control of biological processes. Org Biomol Chem (2006) 1.64
Iceberg alert for NIH. Science (2012) 1.60
Expanding the genetic code of yeast for incorporation of diverse unnatural amino acids via a pyrrolysyl-tRNA synthetase/tRNA pair. J Am Chem Soc (2010) 1.53
Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. J Am Chem Soc (2010) 1.53
Gene silencing in mammalian cells with light-activated antisense agents. Chembiochem (2008) 1.33
Flagellin-F1-V fusion protein is an effective plague vaccine in mice and two species of nonhuman primates. Clin Vaccine Immunol (2008) 1.33
Recent advances in the photochemical control of protein function. Trends Biotechnol (2010) 1.32
Free methionine-(R)-sulfoxide reductase from Escherichia coli reveals a new GAF domain function. Proc Natl Acad Sci U S A (2007) 1.31
Photochemical DNA activation. Org Lett (2007) 1.25
Mesothelin is shed from tumor cells. Cancer Epidemiol Biomarkers Prev (2006) 1.24
Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. J Am Chem Soc (2010) 1.23
Light-activated Cre recombinase as a tool for the spatial and temporal control of gene function in mammalian cells. ACS Chem Biol (2009) 1.23
Pepsin and carbonic anhydrase isoenzyme III as diagnostic markers for laryngopharyngeal reflux disease. Laryngoscope (2004) 1.23
Development of a robust and high throughput method for profiling N-linked glycans derived from plasma glycoproteins by NanoLC-FTICR mass spectrometry. J Proteome Res (2009) 1.19
Activity/stability of human pepsin: implications for reflux attributed laryngeal disease. Laryngoscope (2007) 1.18
Generating permissive site-specific unnatural aminoacyl-tRNA synthetases. Biochemistry (2010) 1.10
Activation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cells. J Am Chem Soc (2010) 1.09
Photochemical activation of protein expression in bacterial cells. Angew Chem Int Ed Engl (2007) 1.04
Light-triggered polymerase chain reaction. Chem Commun (Camb) (2007) 1.04
Sensitive pepsin immunoassay for detection of laryngopharyngeal reflux. Laryngoscope (2005) 1.04
The human mitochondrial tRNAMet: structure/function relationship of a unique modification in the decoding of unconventional codons. J Mol Biol (2010) 1.03
Tricyclic alkaloid core structures assembled by a cyclotrimerization-coupled intramolecular nucleophilic substitution reaction. Org Lett (2010) 1.03
Photocontrol of tyrosine phosphorylation in mammalian cells via genetic encoding of photocaged tyrosine. J Am Chem Soc (2012) 1.02
Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human mitochondrial tRNAMet. Nucleic Acids Res (2008) 1.02
Cleavage of high-molecular-weight kininogen by elastase and tryptase is inhibited by ferritin. Am J Physiol Lung Cell Mol Physiol (2008) 1.01
High-throughput luciferase reporter assay for small-molecule inhibitors of microRNA function. J Biomol Screen (2012) 0.98
Light-activated deoxyguanosine: photochemical regulation of peroxidase activity. Mol Biosyst (2008) 0.98
Effect of pepsin on laryngeal stress protein (Sep70, Sep53, and Hsp70) response: role in laryngopharyngeal reflux disease. Ann Otol Rhinol Laryngol (2006) 0.98
Genetically encoded light-activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells. J Am Chem Soc (2013) 0.98
Photochemical hammerhead ribozyme activation. Bioorg Med Chem Lett (2006) 0.97
Microwave activation of enzymatic catalysis. J Am Chem Soc (2008) 0.96
Optical control of protein function through unnatural amino acid mutagenesis and other optogenetic approaches. ACS Chem Biol (2014) 0.95
Altered -3 substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library. J Biol Chem (2006) 0.95
DNA computation in mammalian cells: microRNA logic operations. J Am Chem Soc (2013) 0.95
A light-activated DNA polymerase. Angew Chem Int Ed Engl (2009) 0.95
Photocaged t7 RNA polymerase for the light activation of transcription and gene function in pro- and eukaryotic cells. Chembiochem (2010) 0.94
Light-controlled synthetic gene circuits. Curr Opin Chem Biol (2012) 0.94
DNA computation: a photochemically controlled AND gate. J Am Chem Soc (2012) 0.93
Light-activation of gene function in mammalian cells via ribozymes. Chem Commun (Camb) (2008) 0.92
Light-regulated RNA-small molecule interactions. Chembiochem (2008) 0.92
EphrinA1 is released in three forms from cancer cells by matrix metalloproteases. Mol Cell Biol (2012) 0.91
The identification of residues that control signal peptidase cleavage fidelity and substrate specificity. J Biol Chem (2004) 0.91
Genetically encoded optochemical probes for simultaneous fluorescence reporting and light activation of protein function with two-photon excitation. J Am Chem Soc (2014) 0.91
C60-fullerenes: detection of intracellular photoluminescence and lack of cytotoxic effects. J Nanobiotechnology (2006) 0.89
Effects of 4-hydroxynonenal on mitochondrial 3-hydroxy-3-methylglutaryl (HMG-CoA) synthase. Free Radic Biol Med (2007) 0.89
Site-specific incorporation of fluorotyrosines into proteins in Escherichia coli by photochemical disguise. Biochemistry (2010) 0.89
A general approach to chemo- and regioselective cyclotrimerization reactions. Angew Chem Int Ed Engl (2007) 0.89
Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes. Chem Commun (Camb) (2014) 0.88
Regulation of transcription through light-activation and light-deactivation of triplex-forming oligonucleotides in mammalian cells. ACS Chem Biol (2012) 0.88
Sequential gene silencing using wavelength-selective caged morpholino oligonucleotides. Angew Chem Int Ed Engl (2014) 0.88
Conserved and variant molecular and functional features of multiple egg yolk precursor proteins (vitellogenins) in white perch (Morone americana) and other teleosts. Mar Biotechnol (NY) (2008) 0.87
Optochemical control of deoxyoligonucleotide function via a nucleobase-caging approach. Acc Chem Res (2013) 0.87
Two rapid catalyst-free click reactions for in vivo protein labeling of genetically encoded strained alkene/alkyne functionalities. Bioconjug Chem (2014) 0.86
A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer. J Support Oncol (2013) 0.85
Spatiotemporal control of microRNA function using light-activated antagomirs. Mol Biosyst (2012) 0.85
A photoactivatable small-molecule inhibitor for light-controlled spatiotemporal regulation of Rho kinase in live embryos. Development (2012) 0.85
A cyclotrimerization route to cannabinoids. Org Lett (2008) 0.84
Light-activated gene editing with a photocaged zinc-finger nuclease. Angew Chem Int Ed Engl (2011) 0.83
Genetic encoding of caged cysteine and caged homocysteine in bacterial and mammalian cells. Chembiochem (2014) 0.83
Photochemical regulation of restriction endonuclease activity. Chembiochem (2009) 0.82
Optochemical control of RNA interference in mammalian cells. Nucleic Acids Res (2013) 0.82
The effect of microwave irradiation on DNA hybridization. Org Biomol Chem (2009) 0.82
Interfacing synthetic DNA logic operations with protein outputs. Angew Chem Int Ed Engl (2014) 0.82
Microwave-mediated nickel-catalyzed cyclotrimerization reactions: total synthesis of illudinine. J Org Chem (2007) 0.81
Heterotaxin: a TGF-β signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos. Chem Biol (2011) 0.81
Microwave-assisted solid-supported alkyne cyclotrimerization reactions for combinatorial chemistry. J Comb Chem (2007) 0.81
Evidence for a novel serum factor distinct from zinc alpha-2 glycoprotein that promotes body fat loss early in the development of cachexia. Nutr Cancer (2010) 0.81
Control of protein function through optochemical translocation. ACS Synth Biol (2014) 0.80
Synthesis of the pyridine core of cyclothiazomycin. Org Lett (2011) 0.80
Cellular delivery and photochemical activation of antisense agents through a nucleobase caging strategy. ACS Chem Biol (2013) 0.80
Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization. Nucleic Acids Res (2009) 0.80
Noncatalytic interactions between glutathione S-transferases and nitroalkene fatty acids modulate nitroalkene-mediated activation of peroxisomal proliferator-activated receptor gamma. Biochemistry (2009) 0.79
Improved synthesis of the two-photon caging group 3-nitro-2-ethyldibenzofuran and its application to a caged thymidine phosphoramidite. Org Lett (2010) 0.79
Intracellular light-activation of riboswitch activity. Chembiochem (2014) 0.79
Reversible light switching of cell signalling by genetically encoded protein dimerization. Chembiochem (2010) 0.79
Microwave-assisted synthesis of unnatural amino acids. Bioorg Med Chem Lett (2008) 0.79
Light-cleavable rapamycin dimer as an optical trigger for protein dimerization. Chem Commun (Camb) (2015) 0.79
Solid-supported [2+2+2] cyclotrimerizations. Chemistry (2006) 0.79
Photochemical control of bacterial signal processing using a light-activated erythromycin. Mol Biosyst (2011) 0.78
Pyridines via solid-supported [2 + 2 + 2] cyclotrimerization. Chem Commun (Camb) (2006) 0.78
Hydrogen peroxide induced activation of gene expression in mammalian cells using boronate estrone derivatives. Angew Chem Int Ed Engl (2012) 0.78
Site-specific promoter caging enables optochemical gene activation in cells and animals. J Am Chem Soc (2014) 0.78
Photocleavable polyethylene glycol for the light-regulation of protein function. Bioconjug Chem (2010) 0.77
Site-specific DNA-doxorubicin conjugates display enhanced cytotoxicity to breast cancer cells. Bioconjug Chem (2014) 0.77