Published in Anal Bioanal Chem on July 08, 2006
Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research. Chem Rev (2013) 1.80
4-Chloro-alpha-cyanocinnamic acid is an advanced, rationally designed MALDI matrix. Proc Natl Acad Sci U S A (2008) 1.03
Proteoglycan sequence. Mol Biosyst (2012) 0.98
MALDI immunoscreening (MiSCREEN): a method for selection of anti-peptide monoclonal antibodies for use in immunoproteomics. J Immunol Methods (2010) 0.94
Ionic liquid matrix for direct UV-MALDI-TOF-MS analysis of dermatan sulfate and chondroitin sulfate oligosaccharides. Anal Chem (2007) 0.90
Matrix assisted ionization vacuum (MAIV), a new ionization method for biological materials analysis using mass spectrometry. Mol Cell Proteomics (2012) 0.84
MALDI Mass Spectrometry Imaging for Visualizing In Situ Metabolism of Endogenous Metabolites and Dietary Phytochemicals. Metabolites (2014) 0.83
Mass Spectrometry Imaging of Therapeutics from Animal Models to Three-Dimensional Cell Cultures. Anal Chem (2015) 0.82
Recent advances in sialic acid-focused glycomics. J Proteomics (2012) 0.78
Global relative quantification with liquid chromatography-matrix-assisted laser desorption ionization time-of-flight (LC-MALDI-TOF)--cross-validation with LTQ-Orbitrap proves reliability and reveals complementary ionization preferences. Mol Cell Proteomics (2013) 0.77
Intact lipid imaging of mouse brain samples: MALDI, nanoparticle-laser desorption ionization, and 40 keV argon cluster secondary ion mass spectrometry. Anal Bioanal Chem (2016) 0.76
Mass spectrometry imaging: a novel technology in rheumatology. Nat Rev Rheumatol (2016) 0.75
Proteome analysis of excretory-secretory proteins of Entamoeba histolytica HM1:IMSS via LC-ESI-MS/MS and LC-MALDI-TOF/TOF. Clin Proteomics (2016) 0.75
MALDI Matrix Research for Biopolymers. Mass Spectrom (Tokyo) (2015) 0.75
Correcting mass isotopomer distributions for naturally occurring isotopes. Biotechnol Bioeng (2002) 1.90
Identification and quantification of feathers, down, and hair of avian and mammalian origin using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal Chem (2002) 1.67
The yeast Kluyveromyces marxianus and its biotechnological potential. Appl Microbiol Biotechnol (2008) 1.61
Genealogy profiling through strain improvement by using metabolic network analysis: metabolic flux genealogy of several generations of lysine-producing corynebacteria. Appl Environ Microbiol (2002) 1.58
Impact of the cold shock phenomenon on quantification of intracellular metabolites in bacteria. Anal Biochem (2004) 1.55
Comparative metabolic flux analysis of lysine-producing Corynebacterium glutamicum cultured on glucose or fructose. Appl Environ Microbiol (2004) 1.50
Amplified expression of fructose 1,6-bisphosphatase in Corynebacterium glutamicum increases in vivo flux through the pentose phosphate pathway and lysine production on different carbon sources. Appl Environ Microbiol (2005) 1.44
Integrated optical sensing of dissolved oxygen in microtiter plates: a novel tool for microbial cultivation. Biotechnol Bioeng (2003) 1.41
Quantitative characterization of metabolism and metabolic shifts during growth of the new human cell line AGE1.HN using time resolved metabolic flux analysis. Bioprocess Biosyst Eng (2010) 1.40
Minibioreactors. Biotechnol Lett (2004) 1.37
In vivo analysis of intracellular amino acid labelings by GC/MS. Anal Biochem (2002) 1.37
In-depth profiling of lysine-producing Corynebacterium glutamicum by combined analysis of the transcriptome, metabolome, and fluxome. J Bacteriol (2004) 1.32
In vivo quantification of intracellular amino acids and intermediates of the methionine pathway in Corynebacterium glutamicum. Anal Biochem (2005) 1.23
Characterization and application of an optical sensor for quantification of dissolved O2 in shake-flasks. Biotechnol Lett (2003) 1.15
Selective permeabilization for the high-throughput measurement of compartmented enzyme activities in mammalian cells. Anal Biochem (2011) 1.14
Two-dimensional reversed-phase x ion-pair reversed-phase HPLC: an alternative approach to high-resolution peptide separation for shotgun proteome analysis. J Proteome Res (2007) 1.13
Metabolic flux analysis in eukaryotes. Curr Opin Biotechnol (2010) 1.13
Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line Hep G2. Toxicol Appl Pharmacol (2009) 1.07
Metabolic flux analysis in systems biology of mammalian cells. Adv Biochem Eng Biotechnol (2012) 1.07
Isotope labeling experiments in metabolomics and fluxomics. Wiley Interdiscip Rev Syst Biol Med (2012) 1.06
On-line oxygen uptake rate and culture viability measurement of animal cell culture using microplates with integrated oxygen sensors. Biotechnol Lett (2004) 1.05
Transcriptional and metabolic responses of Bacillus subtilis to the availability of organic acids: transcription regulation is important but not sufficient to account for metabolic adaptation. Appl Environ Microbiol (2006) 1.05
Metabolic network analysis of lysine producing Corynebacterium glutamicum at a miniaturized scale. Biotechnol Bioeng (2004) 1.02
3D organotypic cultures of human HepaRG cells: a tool for in vitro toxicity studies. Toxicol Sci (2013) 1.01
Optical device for parallel online measurement of dissolved oxygen and pH in shake flask cultures. Bioprocess Biosyst Eng (2009) 1.00
Theoretical aspects of 13C metabolic flux analysis with sole quantification of carbon dioxide labeling. Comput Biol Chem (2005) 1.00
Free intracellular amino acid pools during autonomous oscillations in Saccharomyces cerevisiae. Biotechnol Bioeng (2003) 0.99
Metabolic pathway analysis for rational design of L-methionine production by Escherichia coli and Corynebacterium glutamicum. Metab Eng (2006) 0.99
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry combined with multidimensional scaling, binary hierarchical cluster tree and selected diagnostic masses improves species identification of Neolithic keratin sequences from furs of the Tyrolean Iceman Oetzi. Rapid Commun Mass Spectrom (2012) 0.96
Species identification of Oetzi's clothing with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry based on peptide pattern similarities of hair digests. Rapid Commun Mass Spectrom (2008) 0.96
Physiology of the yeast Kluyveromyces marxianus during batch and chemostat cultures with glucose as the sole carbon source. FEMS Yeast Res (2007) 0.95
Cardiotoxicity testing using pluripotent stem cell-derived human cardiomyocytes and state-of-the-art bioanalytics: a review. J Appl Toxicol (2011) 0.95
Modeling of mixing in 96-well microplates observed with fluorescence indicators. Biotechnol Prog (2002) 0.94
Hybrid optimization for 13C metabolic flux analysis using systems parametrized by compactification. BMC Syst Biol (2008) 0.94
Microplates with integrated oxygen sensing for medium optimization in animal cell culture. Cytotechnology (2005) 0.93
Towards a metabolic and isotopic steady state in CHO batch cultures for reliable isotope-based metabolic profiling. Biotechnol J (2009) 0.91
PH-sensing 96-well microtitre plates for the characterization of acid production by dairy starter cultures. J Dairy Res (2003) 0.91
Doxorubicin increases oxidative metabolism in HL-1 cardiomyocytes as shown by 13C metabolic flux analysis. Toxicol Sci (2011) 0.90
An integrated approach to improved toxicity prediction for the safety assessment during preclinical drug development using Hep G2 cells. Toxicol Appl Pharmacol (2009) 0.88
Numerical bias estimation for mass spectrometric mass isotopomer analysis. Anal Biochem (2009) 0.88
Primary metabolism in the new human cell line AGE1.HN at various substrate levels: increased metabolic efficiency and α1-antitrypsin production at reduced pyruvate load. Appl Microbiol Biotechnol (2011) 0.86
Qualitative and quantitative analysis of low molecular weight compounds by ultraviolet matrix-assisted laser desorption/ionization mass spectrometry using ionic liquid matrices. Rapid Commun Mass Spectrom (2004) 0.86
Engineering the supply chain for protein production/secretion in yeasts and mammalian cells. J Ind Microbiol Biotechnol (2015) 0.85
Quantification of peptides for the monitoring of protease-catalyzed reactions by matrix-assisted laser desorption/ionization mass spectrometry using ionic liquid matrixes. Anal Chem (2006) 0.85
Eukaryotic metabolism: measuring compartment fluxes. Biotechnol J (2011) 0.85
In-depth physiological characterization of primary human hepatocytes in a 3D hollow-fiber bioreactor. J Tissue Eng Regen Med (2011) 0.85
Repeatability of peptide identifications in shotgun proteome analysis employing off-line two-dimensional chromatographic separations and ion-trap MS. J Sep Sci (2009) 0.85
Accumulation of homolanthionine and activation of a novel pathway for isoleucine biosynthesis in Corynebacterium glutamicum McbR deletion strains. J Bacteriol (2006) 0.85
Derivatization of small biomolecules for optimized matrix-assisted laser desorption/ionization mass spectrometry. J Mass Spectrom (2002) 0.85
A system of miniaturized stirred bioreactors for parallel continuous cultivation of yeast with online measurement of dissolved oxygen and off-gas. Biotechnol Bioeng (2012) 0.85
Software tool for automated processing of 13C labeling data from mass spectrometric spectra. Biotechniques (2003) 0.84
Metabolic flux screening of Saccharomyces cerevisiae single knockout strains on glucose and galactose supports elucidation of gene function. J Biotechnol (2007) 0.84
Real-time in situ viability assessment in a 3D bioreactor with liver cells using resazurin assay. Cytotechnology (2012) 0.83
Respirometric 13C flux analysis--Part II: in vivo flux estimation of lysine-producing Corynebacterium glutamicum. Metab Eng (2006) 0.83
Stable isotope-assisted metabolomics to detect metabolic flux changes in mammalian cell cultures. Curr Opin Biotechnol (2012) 0.83
Mixed glucose and lactate uptake by Corynebacterium glutamicum through metabolic engineering. Biotechnol J (2011) 0.83
Dynamics of growth and metabolism controlled by glutamine availability in Chinese hamster ovary cells. Appl Microbiol Biotechnol (2013) 0.82
Online monitoring of oxygen in spinner flasks. Biotechnol Lett (2009) 0.82
Investigation of the central carbon metabolism of Sorangium cellulosum: metabolic network reconstruction and quantification of pathway fluxes. J Microbiol Biotechnol (2009) 0.81
Metabolic engineering of the purine biosynthetic pathway in Corynebacterium glutamicum results in increased intracellular pool sizes of IMP and hypoxanthine. Microb Cell Fact (2012) 0.81
13C metabolic flux analysis for larger scale cultivation using gas chromatography-combustion-isotope ratio mass spectrometry. Metab Eng (2010) 0.81
The SEURAT-1 approach towards animal free human safety assessment. ALTEX (2014) 0.81
Physiological response of Corynebacterium glutamicum to oxidative stress induced by deletion of the transcriptional repressor McbR. Microbiology (2008) 0.81
Zinc ion-induced domain organization in metallo-beta-lactamases: a flexible "zinc arm" for rapid metal ion transfer? J Biol Chem (2009) 0.80
Metabolite profiling studies in Saccharomyces cerevisiae: an assisting tool to prioritize host targets for antiviral drug screening. Microb Cell Fact (2009) 0.80
Studies on ternary metallo-beta lactamase-inhibitor complexes using electrospray ionization mass spectrometry. J Am Soc Mass Spectrom (2006) 0.80
Esterase autodisplay: enzyme engineering and whole-cell activity determination in microplates with pH sensors. Appl Environ Microbiol (2008) 0.80
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for metabolic flux analyses using isotope-labeled ethanol. Rapid Commun Mass Spectrom (2007) 0.80
N-acetylation and phosphorylation of Sec complex subunits in the ER membrane. BMC Cell Biol (2012) 0.79
Metabolic flux rearrangement in the amino acid metabolism reduces ammonia stress in the α1-antitrypsin producing human AGE1.HN cell line. Metab Eng (2012) 0.79
Matrix-assisted laser desorption/ionization mass spectrometry for the characterization of ionic liquids and the analysis of amino acids, peptides and proteins in ionic liquids. J Mass Spectrom (2004) 0.79
Quantitative matrix-assisted laser desorption/ionization mass spectrometry for the determination of enzyme activities. Anal Biochem (2004) 0.79
Metabolite channeling and compartmentation in the human cell line AGE1.HN determined by 13C labeling experiments and 13C metabolic flux analysis. J Biosci Bioeng (2011) 0.79
Respirometric 13C flux analysis, Part I: design, construction and validation of a novel multiple reactor system using on-line membrane inlet mass spectrometry. Metab Eng (2006) 0.79
A 2D reversed-phase x ion-pair reversed-phase HPLC-MALDI TOF/TOF-MS approach for shotgun proteome analysis. Anal Bioanal Chem (2008) 0.79
Quercetin treatment changes fluxes in the primary metabolism and increases culture longevity and recombinant α₁-antitrypsin production in human AGE1.HN cells. Appl Microbiol Biotechnol (2011) 0.78
Production of L-lysine on different silage juices using genetically engineered Corynebacterium glutamicum. J Biotechnol (2012) 0.78
Metabolic flux analysis gives an insight on verapamil induced changes in central metabolism of HL-1 cells. J Biotechnol (2011) 0.78
Metabolic profiling using HPLC allows classification of drugs according to their mechanisms of action in HL-1 cardiomyocytes. Toxicol Appl Pharmacol (2011) 0.78
High throughput, non-invasive and dynamic toxicity screening on adherent cells using respiratory measurements. Toxicol In Vitro (2009) 0.78
Gas sensing in microplates with optodes: influence of oxygen exchange between sample, air, and plate material. Biotechnol Bioeng (2005) 0.78
Pyridinium-based ionic liquid matrices can improve the identification of proteins by peptide mass-fingerprint analysis with matrix-assisted laser desorption/ionization mass spectrometry. Anal Bioanal Chem (2005) 0.77
Macroscopic modeling of mammalian cell growth and metabolism. Appl Microbiol Biotechnol (2015) 0.77
Metabolism and metabolic burden by α1-antitrypsin production in human AGE1.HN cells. Metab Eng (2013) 0.77
Proteolytic peptide patterns as indicators for fungal infections and nonfungal affections of human nails measured by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal Biochem (2005) 0.77
Controlled feeding of hydrogen peroxide as oxygen source improves production of 5-ketofructose from L-sorbose using engineered pyranose 2-oxidase from Peniophora gigantea. Biotechnol Bioeng (2012) 0.77
Metabolic fluxes in Schizosaccharomyces pombe grown on glucose and mixtures of glycerol and acetate. Appl Microbiol Biotechnol (2013) 0.77
Multistep synthesis of UDP-glucose using tailored, permeabilized cells of E. coli. Appl Biochem Biotechnol (2015) 0.77
Rapid selection of peptide containing fractions in off-line 2-D HPLC in shotgun proteome analysis by screening with MALDI TOF MS. Proteomics (2009) 0.76
Quantitation of intracellular purine intermediates in different Corynebacteria using electrospray LC-MS/MS. Anal Bioanal Chem (2012) 0.76
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: a new tool in diagnostic investigation of nail disorders? Exp Dermatol (2009) 0.76
Directed multistep biocatalysis using tailored permeabilized cells. Adv Biochem Eng Biotechnol (2013) 0.76
Toward preclinical predictive drug testing for metabolism and hepatotoxicity by using in vitro models derived from human embryonic stem cells and human cell lines - a report on the Vitrocellomics EU-project. Altern Lab Anim (2011) 0.76
Mass isotopomer analysis of nucleosides isolated from RNA and DNA using GC/MS. Anal Chem (2014) 0.76
Identification of oxidized methionine residues in peptides containing two methionine residues by derivatization and matrix-assisted laser desorption/ionization mass spectrometry. Proteomics (2002) 0.75
Microplates with integrated oxygen sensors for kinetic cell respiration measurement and cytotoxicity testing in primary and secondary cell lines. Assay Drug Dev Technol (2005) 0.75
Dynamic calibration and dissolved gas analysis using membrane inlet mass spectrometry for the quantification of cell respiration. Rapid Commun Mass Spectrom (2003) 0.75
Methods for biocatalyst screening. Adv Biochem Eng Biotechnol (2002) 0.75
Quantification of S-adenosyl methionine in microbial cell extracts. Biotechnol Lett (2006) 0.75
Quenching methods for the analysis of intracellular metabolites. Methods Mol Biol (2014) 0.75