Published in Biotechnol Bioeng on March 30, 2003
Validation of a high-throughput fermentation system based on online monitoring of biomass and fluorescence in continuously shaken microtiter plates. Microb Cell Fact (2009) 1.50
Indicators for optical oxygen sensors. Bioanal Rev (2012) 1.34
Miniature bioreactors: current practices and future opportunities. Microb Cell Fact (2006) 1.30
A new wireless system for decentralised measurement of physiological parameters from shake flasks. Microb Cell Fact (2006) 1.11
Fluorescent microparticles for sensing cell microenvironment oxygen levels within 3D scaffolds. Biomaterials (2009) 1.06
Scale-up from microtiter plate to laboratory fermenter: evaluation by online monitoring techniques of growth and protein expression in Escherichia coli and Hansenula polymorpha fermentations. Microb Cell Fact (2009) 1.05
High yield recombinant penicillin G amidase production and export into the growth medium using Bacillus megaterium. Microb Cell Fact (2006) 0.99
Review of microfluidic microbioreactor technology for high-throughput submerged microbiological cultivation. Biomicrofluidics (2013) 0.93
Microplates with integrated oxygen sensing for medium optimization in animal cell culture. Cytotechnology (2005) 0.93
Pitfalls in optical on-line monitoring for high-throughput screening of microbial systems. Microb Cell Fact (2014) 0.89
Suppressing glucose uptake and acetic acid production increases membrane protein overexpression in Escherichia coli. Microb Cell Fact (2011) 0.81
Online monitoring of dissolved oxygen tension in microtiter plates based on infrared fluorescent oxygen-sensitive nanoparticles. Microb Cell Fact (2015) 0.81
A microfluidic device to study cancer metastasis under chronic and intermittent hypoxia. Biomicrofluidics (2014) 0.80
Metabolite profiling studies in Saccharomyces cerevisiae: an assisting tool to prioritize host targets for antiviral drug screening. Microb Cell Fact (2009) 0.80
Transient hypoxia improves matrix properties in tissue engineered cartilage. J Orthop Res (2012) 0.80
Fluorescent silica particles for monitoring oxygen levels in three-dimensional heterogeneous cellular structures. Biotechnol Bioeng (2012) 0.79
Spatially monitoring oxygen level in 3D microfabricated cell culture systems using optical oxygen sensing beads. Lab Chip (2013) 0.78
Adapting yeast as model to study ricin toxin a uptake and trafficking. Toxins (Basel) (2011) 0.78
H/KDEL receptors mediate host cell intoxication by a viral A/B toxin in yeast. Sci Rep (2016) 0.77
High-throughput workflow for monitoring and mining bioprocess data and its application to inferring the physiological response of Escherichia coli to perturbations. Appl Environ Microbiol (2011) 0.76
Quasi-continuous parallel online scattered light, fluorescence and dissolved oxygen tension measurement combined with monitoring of the oxygen transfer rate in each well of a shaken microtiter plate. Microb Cell Fact (2016) 0.75
Complete genome sequence of the myxobacterium Sorangium cellulosum. Nat Biotechnol (2007) 2.43
Correcting mass isotopomer distributions for naturally occurring isotopes. Biotechnol Bioeng (2002) 1.90
Sampling for metabolome analysis of microorganisms. Anal Chem (2007) 1.89
Identification and quantification of feathers, down, and hair of avian and mammalian origin using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal Chem (2002) 1.67
The yeast Kluyveromyces marxianus and its biotechnological potential. Appl Microbiol Biotechnol (2008) 1.61
OpenFLUX: efficient modelling software for 13C-based metabolic flux analysis. Microb Cell Fact (2009) 1.61
Genealogy profiling through strain improvement by using metabolic network analysis: metabolic flux genealogy of several generations of lysine-producing corynebacteria. Appl Environ Microbiol (2002) 1.58
Impact of the cold shock phenomenon on quantification of intracellular metabolites in bacteria. Anal Biochem (2004) 1.55
Comparative metabolic flux analysis of lysine-producing Corynebacterium glutamicum cultured on glucose or fructose. Appl Environ Microbiol (2004) 1.50
Systems metabolic engineering of xylose-utilizing Corynebacterium glutamicum for production of 1,5-diaminopentane. Biotechnol J (2013) 1.50
From zero to hero--design-based systems metabolic engineering of Corynebacterium glutamicum for L-lysine production. Metab Eng (2011) 1.47
Characterization of the metabolic shift between oxidative and fermentative growth in Saccharomyces cerevisiae by comparative 13C flux analysis. Microb Cell Fact (2005) 1.47
Amplified expression of fructose 1,6-bisphosphatase in Corynebacterium glutamicum increases in vivo flux through the pentose phosphate pathway and lysine production on different carbon sources. Appl Environ Microbiol (2005) 1.44
Bio-based production of chemicals, materials and fuels -Corynebacterium glutamicum as versatile cell factory. Curr Opin Biotechnol (2011) 1.43
Quantitative characterization of metabolism and metabolic shifts during growth of the new human cell line AGE1.HN using time resolved metabolic flux analysis. Bioprocess Biosyst Eng (2010) 1.40
In vivo analysis of intracellular amino acid labelings by GC/MS. Anal Biochem (2002) 1.37
Minibioreactors. Biotechnol Lett (2004) 1.37
Indicators for optical oxygen sensors. Bioanal Rev (2012) 1.34
In-depth profiling of lysine-producing Corynebacterium glutamicum by combined analysis of the transcriptome, metabolome, and fluxome. J Bacteriol (2004) 1.32
Ultrabright oxygen optodes based on cyclometalated iridium(III) coumarin complexes. Anal Chem (2007) 1.29
In vivo quantification of intracellular amino acids and intermediates of the methionine pathway in Corynebacterium glutamicum. Anal Biochem (2005) 1.23
Industrial biotechnology of Pseudomonas putida and related species. Appl Microbiol Biotechnol (2012) 1.20
Systems-wide metabolic pathway engineering in Corynebacterium glutamicum for bio-based production of diaminopentane. Metab Eng (2010) 1.17
Characterization and application of an optical sensor for quantification of dissolved O2 in shake-flasks. Biotechnol Lett (2003) 1.15
Selective permeabilization for the high-throughput measurement of compartmented enzyme activities in mammalian cells. Anal Biochem (2011) 1.14
Two-dimensional reversed-phase x ion-pair reversed-phase HPLC: an alternative approach to high-resolution peptide separation for shotgun proteome analysis. J Proteome Res (2007) 1.13
Metabolic flux analysis in eukaryotes. Curr Opin Biotechnol (2010) 1.13
Metabolic flux engineering of L-lysine production in Corynebacterium glutamicum--over expression and modification of G6P dehydrogenase. J Biotechnol (2007) 1.12
Characterization and control of fungal morphology for improved production performance in biotechnology. J Biotechnol (2012) 1.09
Systems and synthetic metabolic engineering for amino acid production - the heartbeat of industrial strain development. Curr Opin Biotechnol (2012) 1.09
Determination of oxygen gradients in engineered tissue using a fluorescent sensor. Biotechnol Bioeng (2002) 1.08
Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line Hep G2. Toxicol Appl Pharmacol (2009) 1.07
Metabolic flux analysis in systems biology of mammalian cells. Adv Biochem Eng Biotechnol (2012) 1.07
An optical multifrequency phase-modulation method using microbeads for measuring intracellular oxygen concentrations in plants. Biophys J (2005) 1.06
Isotope labeling experiments in metabolomics and fluxomics. Wiley Interdiscip Rev Syst Biol Med (2012) 1.06
On-line oxygen uptake rate and culture viability measurement of animal cell culture using microplates with integrated oxygen sensors. Biotechnol Lett (2004) 1.05
Transcriptional and metabolic responses of Bacillus subtilis to the availability of organic acids: transcription regulation is important but not sufficient to account for metabolic adaptation. Appl Environ Microbiol (2006) 1.05
Time-resolved pH/pO2 mapping with luminescent hybrid sensors. Anal Chem (2007) 1.04
Intracellular O2 sensing probe based on cell-penetrating phosphorescent nanoparticles. ACS Nano (2011) 1.03
Ionic (liquid) matrices for matrix-assisted laser desorption/ionization mass spectrometry-applications and perspectives. Anal Bioanal Chem (2006) 1.02
Metabolic network analysis of lysine producing Corynebacterium glutamicum at a miniaturized scale. Biotechnol Bioeng (2004) 1.02
Response of the central metabolism of Escherichia coli to modified expression of the gene encoding the glucose-6-phosphate dehydrogenase. FEBS Lett (2007) 1.01
Fluorescent pH sensors with negligible sensitivity to ionic strength. Analyst (2004) 1.01
3D organotypic cultures of human HepaRG cells: a tool for in vitro toxicity studies. Toxicol Sci (2013) 1.01
Consequences of phosphoenolpyruvate:sugar phosphotranferase system and pyruvate kinase isozymes inactivation in central carbon metabolism flux distribution in Escherichia coli. Microb Cell Fact (2012) 1.01
Optical device for parallel online measurement of dissolved oxygen and pH in shake flask cultures. Bioprocess Biosyst Eng (2009) 1.00
Getting the big beast to work--systems biotechnology of Bacillus megaterium for novel high-value proteins. J Biotechnol (2012) 1.00
Novel optical trace oxygen sensors based on platinum(II) and palladium(II) complexes with 5,10,15,20-meso-tetrakis-(2,3,4,5,6-pentafluorphenyl)-porphyrin covalently immobilized on silica-gel particles. Anal Chim Acta (2011) 1.00
Poly(styrene-block-vinylpyrrolidone) beads as a versatile material for simple fabrication of optical nanosensors. Anal Chem (2008) 1.00
Morphology engineering of Aspergillus niger for improved enzyme production. Biotechnol Bioeng (2010) 1.00
Theoretical aspects of 13C metabolic flux analysis with sole quantification of carbon dioxide labeling. Comput Biol Chem (2005) 1.00
Free intracellular amino acid pools during autonomous oscillations in Saccharomyces cerevisiae. Biotechnol Bioeng (2003) 0.99
Metabolic fluxes in the central carbon metabolism of Dinoroseobacter shibae and Phaeobacter gallaeciensis, two members of the marine Roseobacter clade. BMC Microbiol (2009) 0.99
Metabolic pathway analysis for rational design of L-methionine production by Escherichia coli and Corynebacterium glutamicum. Metab Eng (2006) 0.99
Metabolic responses to pyruvate kinase deletion in lysine producing Corynebacterium glutamicum. Microb Cell Fact (2008) 0.98
Systems metabolic engineering of Escherichia coli for production of the antitumor drugs violacein and deoxyviolacein. Metab Eng (2013) 0.97
Improved enzyme production by bio-pellets of Aspergillus niger: targeted morphology engineering using titanate microparticles. Biotechnol Bioeng (2011) 0.97
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry combined with multidimensional scaling, binary hierarchical cluster tree and selected diagnostic masses improves species identification of Neolithic keratin sequences from furs of the Tyrolean Iceman Oetzi. Rapid Commun Mass Spectrom (2012) 0.96
Species identification of Oetzi's clothing with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry based on peptide pattern similarities of hair digests. Rapid Commun Mass Spectrom (2008) 0.96
Physiology of the yeast Kluyveromyces marxianus during batch and chemostat cultures with glucose as the sole carbon source. FEMS Yeast Res (2007) 0.95
Metabolic engineering of cellular transport for overproduction of the platform chemical 1,5-diaminopentane in Corynebacterium glutamicum. Metab Eng (2011) 0.95
Cardiotoxicity testing using pluripotent stem cell-derived human cardiomyocytes and state-of-the-art bioanalytics: a review. J Appl Toxicol (2011) 0.95
Phosphorescent platinum(II) and palladium(II) complexes with azatetrabenzoporphyrins-new red laser diode-compatible indicators for optical oxygen sensing. ACS Appl Mater Interfaces (2010) 0.94
Debottlenecking recombinant protein production in Bacillus megaterium under large-scale conditions--targeted precursor feeding designed from metabolomics. Biotechnol Bioeng (2012) 0.94
Hybrid optimization for 13C metabolic flux analysis using systems parametrized by compactification. BMC Syst Biol (2008) 0.94
Modeling of mixing in 96-well microplates observed with fluorescence indicators. Biotechnol Prog (2002) 0.94
Blue LED excitable temperature sensors based on a new europium(III) chelate. J Fluoresc (2008) 0.94
Tunable phosphorescent NIR oxygen indicators based on mixed benzo- and naphthoporphyrin complexes. Inorg Chem (2010) 0.94
Precipitation as a simple and versatile method for preparation of optical nanochemosensors. Talanta (2009) 0.93
Flux Design: In silico design of cell factories based on correlation of pathway fluxes to desired properties. BMC Syst Biol (2009) 0.93
Microbial production of the drugs violacein and deoxyviolacein: analytical development and strain comparison. Biotechnol Lett (2011) 0.93
Identification and elimination of the competing N-acetyldiaminopentane pathway for improved production of diaminopentane by Corynebacterium glutamicum. Appl Environ Microbiol (2010) 0.93
Microplates with integrated oxygen sensing for medium optimization in animal cell culture. Cytotechnology (2005) 0.93
Microparticle based morphology engineering of filamentous microorganisms for industrial bio-production. Biotechnol Lett (2012) 0.92
Integration of in vivo and in silico metabolic fluxes for improvement of recombinant protein production. Metab Eng (2011) 0.92
Systems biology of recombinant protein production using Bacillus megaterium. Methods Enzymol (2011) 0.92
Appropriate sampling for intracellular amino acid analysis in five phylogenetically different yeasts. Biotechnol Lett (2008) 0.92
Sol-gel based optical carbon dioxide sensor employing dual luminophore referencing for application in food packaging technology. Analyst (2002) 0.91
Towards a metabolic and isotopic steady state in CHO batch cultures for reliable isotope-based metabolic profiling. Biotechnol J (2009) 0.91
Strongly Phosphorescent Iridium(III)-Porphyrins - New Oxygen Indicators with Tuneable Photophysical Properties and Functionalities. Eur J Inorg Chem (2011) 0.91
Metabolic network simulation using logical loop algorithm and Jacobian matrix. Metab Eng (2004) 0.91
PH-sensing 96-well microtitre plates for the characterization of acid production by dairy starter cultures. J Dairy Res (2003) 0.91
Advanced biotechnology: metabolically engineered cells for the bio-based production of chemicals and fuels, materials, and health-care products. Angew Chem Int Ed Engl (2015) 0.90
Filamentous fungi in good shape: microparticles for tailor-made fungal morphology and enhanced enzyme production. Bioeng Bugs (2011) 0.90
Comparative study on central metabolic fluxes of Bacillus megaterium strains in continuous culture using 13C labelled substrates. Bioprocess Biosyst Eng (2006) 0.90
In vivo phosphorescence imaging of pO2 using planar oxygen sensors. Microcirculation (2005) 0.90