Published in J Biol Chem on August 02, 2006
Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase. Proc Natl Acad Sci U S A (2009) 1.63
The X-ray crystal structure of human aminopeptidase N reveals a novel dimer and the basis for peptide processing. J Biol Chem (2012) 1.12
Distribution and biochemical properties of an M1-family aminopeptidase in Plasmodium falciparum indicate a role in vacuolar hemoglobin catabolism. J Biol Chem (2011) 0.99
Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros. PLoS Negl Trop Dis (2010) 0.90
Engagement of the S1, S1' and S2' subsites drives efficient catalysis of peptide bond hydrolysis by the M1-family aminopeptidase from Plasmodium falciparum. Mol Biochem Parasitol (2012) 0.87
Intestinal peptidases form functional complexes with the neutral amino acid transporter B(0)AT1. Biochem J (2012) 0.84
Detecting clusters of mutations. PLoS One (2008) 0.84
Hybrid molecular structure of the giant protease tripeptidyl peptidase II. Nat Struct Mol Biol (2010) 0.84
An integrated approach to the ligand binding specificity of Neisseria meningitidis M1 alanine aminopeptidase by fluorogenic substrate profiling, inhibitory studies and molecular modeling. Biochimie (2012) 0.84
Exploration of Sitagliptin as a potential inhibitor for the M1 Alanine aminopeptidase enzyme in Plasmodium falciparum using computational docking. Bioinformation (2013) 0.83
Identification of threonine 348 as a residue involved in aminopeptidase A substrate specificity. J Biol Chem (2009) 0.83
Dipeptidyl aminopeptidase IV from Stenotrophomonas maltophilia exhibits activity against a substrate containing a 4-hydroxyproline residue. J Bacteriol (2008) 0.83
Aminopeptidase B, a glucagon-processing enzyme: site directed mutagenesis of the Zn2+-binding motif and molecular modelling. BMC Biochem (2007) 0.81
Functional and genomic analyses of alpha-solenoid proteins. PLoS One (2013) 0.81
Glu121-Lys319 salt bridge between catalytic and N-terminal domains is pivotal for the activity and stability of Escherichia coli aminopeptidase N. Protein Sci (2012) 0.81
A naturally variable residue in the S1 subsite of M1 family aminopeptidases modulates catalytic properties and promotes functional specialization. J Biol Chem (2013) 0.81
Functional interpretation of APN receptor from M.sexta using a molecular model. Bioinformation (2009) 0.79
Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases. J Med Chem (2014) 0.78
Discovery of inhibitors of insulin-regulated aminopeptidase as cognitive enhancers. Int J Hypertens (2012) 0.78
The Plasmodium falciparum malaria M1 alanyl aminopeptidase (PfA-M1): insights of catalytic mechanism and function from MD simulations. PLoS One (2011) 0.77
Development of Synthetic Aminopeptidase N/CD13 Inhibitors to Overcome Cancer Metastasis and Angiogenesis. ACS Med Chem Lett (2012) 0.76
LYP, a novel bestatin derivative, inhibits cell growth and suppresses APN/CD13 activity in human ovarian carcinoma cells more potently than bestatin. Invest New Drugs (2010) 0.76
3'-RACE Amplification of Aminopeptidase N Gene from Anopheles stephensi Applicable in Transmission Blocking Vaccines. Avicenna J Med Biotechnol (2012) 0.76
Tma108, a putative M1 aminopeptidase, is a specific nascent chain-associated protein in Saccharomyces cerevisiae. Nucleic Acids Res (2016) 0.75
Structural basis for the inhibition of M1 family aminopeptidases by the natural product actinonin: Crystal structure in complex with E. coli aminopeptidase N. Protein Sci (2015) 0.75
Proposed Bioactive Conformations of Opiorphin, an Endogenous Dual APN/NEP Inhibitor. ACS Med Chem Lett (2011) 0.75
Histidine 379 of human laeverin/aminopeptidase Q, a nonconserved residue within the exopeptidase motif, defines its distinctive enzymatic properties. J Biol Chem (2009) 0.75
Exploring ligand dissociation pathways from aminopeptidase N using random acceleration molecular dynamics simulation. J Mol Model (2016) 0.75
A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A (2006) 5.24
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics. Mol Cell Biol (2007) 3.03
The origin of planetary impactors in the inner solar system. Science (2005) 3.01
A crucial role for adipose tissue p53 in the regulation of insulin resistance. Nat Med (2009) 2.65
A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 21q. Genome Res (2004) 2.56
Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation. J Biol Chem (2003) 2.45
Living donor liver transplantation: the Asian perspective. Transplantation (2014) 2.13
Retracted The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. Cell (2003) 1.88
Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation. Genes Dev (2008) 1.87
Single center experience of 39 patients with preoperative portal vein thrombosis among 404 adult living donor liver transplantations. Liver Transpl (2006) 1.81
High-resolution DNA methylome analysis of primordial germ cells identifies gender-specific reprogramming in mice. Genome Res (2013) 1.75
Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway. Arterioscler Thromb Vasc Biol (2012) 1.75
Meningitis-retention syndrome. An unrecognized clinical condition. J Neurol (2005) 1.72
Living donor liver transplantation with reduced monosegments for neonates and small infants. Transplantation (2007) 1.61
Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging. Nucleic Acids Res (2012) 1.61
Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation. Proc Natl Acad Sci U S A (2003) 1.59
Mouse oocyte methylomes at base resolution reveal genome-wide accumulation of non-CpG methylation and role of DNA methyltransferases. PLoS Genet (2013) 1.57
Hemoperfusion with a high-mobility group box 1 adsorption column can prevent the occurrence of hepatic ischemia-reperfusion injury in rats. Crit Care Med (2010) 1.51
Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo. Genes Dev (2004) 1.49
A histone chaperone, DEK, transcriptionally coactivates a nuclear receptor. Genes Dev (2009) 1.49
Living donor liver transplantation as a second-line therapeutic strategy for patients with hepatocellular carcinoma. Liver Transpl (2006) 1.48
Survival in nonocclusive mesenteric ischemia: early diagnosis by multidetector row computed tomography and early treatment with continuous intravenous high-dose prostaglandin E(1). Ann Surg (2007) 1.47
Barrier proteins remodel and modify chromatin to restrict silenced domains. Mol Cell Biol (2004) 1.47
Living-donor liver transplantation with monosegments. Transplantation (2003) 1.45
Transcriptional activation of polycomb-repressed genes by ZRF1. Nature (2010) 1.44
Sox9 and p300 cooperatively regulate chromatin-mediated transcription. J Biol Chem (2005) 1.44
Proteomic analysis of in vivo 14-3-3 interactions in the yeast Saccharomyces cerevisiae. Biochemistry (2007) 1.43
Linker histone variants control chromatin dynamics during early embryogenesis. Proc Natl Acad Sci U S A (2005) 1.43
The adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase. EMBO J (2002) 1.41
The conserved kinase NHK-1 is essential for mitotic progression and unifying acentrosomal meiotic spindles in Drosophila melanogaster. J Cell Biol (2005) 1.41
Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2 alpha kinase GCN2. J Biol Chem (2003) 1.41
Structure and function of the PB1 domain, a protein interaction module conserved in animals, fungi, amoebas, and plants. Sci STKE (2007) 1.41
Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity. PLoS Genet (2012) 1.40
Discovery of the first insect nidovirus, a missing evolutionary link in the emergence of the largest RNA virus genomes. PLoS Pathog (2011) 1.40
Long-term outcome and metastatic risk after endoscopic resection of superficial esophageal squamous cell carcinoma. Am J Gastroenterol (2013) 1.39
The resurgence of Coulter counting for analyzing nanoscale objects. Analyst (2004) 1.33
In vivo characterization of bone marrow-derived fibroblasts recruited into fibrotic lesions. Stem Cells (2005) 1.31
Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro. Mol Cell Biol (2002) 1.31
A histone code in meiosis: the histone kinase, NHK-1, is required for proper chromosomal architecture in Drosophila oocytes. Genes Dev (2005) 1.30
The Watanabe heritable hyperlipidemic (WHHL) rabbit, its characteristics and history of development: a tribute to the late Dr. Yoshio Watanabe. Atherosclerosis (2009) 1.28
Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein. Mol Cell (2011) 1.28
Regulation of histone acetylation and nucleosome assembly by transcription factor JDP2. Nat Struct Mol Biol (2006) 1.27
Podoplanin-positive fibroblasts enhance lung adenocarcinoma tumor formation: podoplanin in fibroblast functions for tumor progression. Cancer Res (2011) 1.26
Absolute quantification of the budding yeast transcriptome by means of competitive PCR between genomic and complementary DNAs. BMC Genomics (2008) 1.24
Inhibitors of Plasmodium falciparum methionine aminopeptidase 1b possess antimalarial activity. Proc Natl Acad Sci U S A (2006) 1.23
Atrogin-1 ubiquitin ligase is upregulated by doxorubicin via p38-MAP kinase in cardiac myocytes. Cardiovasc Res (2008) 1.22
Development of an animal model for spontaneous myocardial infarction (WHHLMI rabbit). Arterioscler Thromb Vasc Biol (2003) 1.20
Transcriptional activators in yeast. Nucleic Acids Res (2006) 1.20
Small-for-size graft in living donor liver transplantation: how far should we go? Liver Transpl (2003) 1.19
Molecular recognition in dimerization between PB1 domains. J Biol Chem (2003) 1.18
Usefulness of the Kyoto criteria as expanded selection criteria for liver transplantation for hepatocellular carcinoma. Surgery (2013) 1.17
Outcomes of adult-to-adult living donor liver transplantation: a single institution's experience with 335 consecutive cases. Ann Surg (2007) 1.15
A functional single-nucleotide polymorphism in the human cytidine deaminase gene contributing to ara-C sensitivity. Pharmacogenetics (2003) 1.13
Living donor liver transplantation for patients with HCC exceeding the Milan criteria: a proposal of expanded criteria. Dig Dis (2007) 1.11
Mass spectrometry-based approaches toward absolute quantitative proteomics. Curr Genomics (2008) 1.10
Characterization of Propionibacterium acnes isolates from sarcoid and non-sarcoid tissues with special reference to cell invasiveness, serotype, and trigger factor gene polymorphism. Microb Pathog (2008) 1.08
A novel strategy to design highly specific PCR primers based on the stability and uniqueness of 3'-end subsequences. Bioinformatics (2005) 1.05
A novel Cdc42-interacting domain of the yeast polarity establishment protein Bem1. Implications for modulation of mating pheromone signaling. J Biol Chem (2006) 1.04
A Cenozoic record of the equatorial Pacific carbonate compensation depth. Nature (2012) 1.04
Taurine inhibits apoptosis by preventing formation of the Apaf-1/caspase-9 apoptosome. Am J Physiol Cell Physiol (2004) 1.04
Isoflavones stimulate estrogen receptor-mediated core histone acetylation. Biochem Biophys Res Commun (2004) 1.03
N-cadherin-mediated cell adhesion determines the plasticity for cell alignment in response to mechanical stretch in cultured cardiomyocytes. Biochem Biophys Res Commun (2005) 1.03
Structure of the biotin carboxylase subunit of pyruvate carboxylase from Aquifex aeolicus at 2.2 A resolution. Acta Crystallogr D Biol Crystallogr (2004) 1.03
The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells. J Pharmacol Exp Ther (2009) 1.03
Effect of differences in cancer cells and tumor growth sites on recruiting bone marrow-derived endothelial cells and myofibroblasts in cancer-induced stroma. Int J Cancer (2005) 1.03
Interaction of N-acetylglutamate kinase with a PII-like protein in rice. Plant Cell Physiol (2004) 1.02
In vivo and in vitro characterization of human fibroblasts recruited selectively into human cancer stroma. Int J Cancer (2005) 1.02
p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure. Cell Metab (2012) 1.02
Identification of cardiac myocytes as the target of interleukin 11, a cardioprotective cytokine. Cytokine (2007) 1.02
NMR analysis of lignins in CAD-deficient plants. Part 1. Incorporation of hydroxycinnamaldehydes and hydroxybenzaldehydes into lignins. Org Biomol Chem (2003) 1.01
MicroRNA-22 regulates hypoxia signaling in colon cancer cells. PLoS One (2011) 1.01
Identification of a five-pass transmembrane protein family localizing in the Golgi apparatus and the ER. Biochem Biophys Res Commun (2003) 1.01
Development of Capsicum EST-SSR markers for species identification and in silico mapping onto the tomato genome sequence. Mol Breed (2012) 1.01
Electrokinetic trapping and concentration enrichment of DNA in a microfluidic channel. J Am Chem Soc (2003) 1.00
The PB1 domain and the PC motif-containing region are structurally similar protein binding modules. EMBO J (2003) 0.99
Taurine prevents the ischemia-induced apoptosis in cultured neonatal rat cardiomyocytes through Akt/caspase-9 pathway. Biochem Biophys Res Commun (2004) 0.98
N-cadherin signals through Rac1 determine the localization of connexin 43 in cardiac myocytes. J Mol Cell Cardiol (2006) 0.98
Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism. PLoS One (2013) 0.98
Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250. Acta Crystallogr D Biol Crystallogr (2009) 0.97
B cell-derived vascular endothelial growth factor A promotes lymphangiogenesis and high endothelial venule expansion in lymph nodes. J Immunol (2010) 0.97
Edaravone attenuates cerebral ischemic injury by suppressing aquaporin-4. Biochem Biophys Res Commun (2009) 0.96
Isolated trochlear nerve palsy in herpes zoster ophthalmicus. Intern Med (2007) 0.96
Crystal structure of serine dehydrogenase from Escherichia coli: important role of the C-terminal region for closed-complex formation. J Biochem (2011) 0.96
C-reactive protein induces high-mobility group box-1 protein release through activation of p38MAPK in macrophage RAW264.7 cells. Cardiovasc Pathol (2007) 0.96
A synthetic protein approach toward accurate mass spectrometric quantification of component stoichiometry of multiprotein complexes. J Proteome Res (2007) 0.95
Signals through gp130 upregulate Wnt5a and contribute to cell adhesion in cardiac myocytes. FEBS Lett (2004) 0.95
Rac1 activity is required for cardiac myocyte alignment in response to mechanical stress. Biochem Biophys Res Commun (2006) 0.95
Electron microscopic studies on bactericidal effects of electrolyzed acidic water on bacteria derived from kendo protective equipment. Environ Health Prev Med (2006) 0.95
Preparation of primary amine-modified gold nanoparticles and their transfection ability into cultivated cells. Chem Commun (Camb) (2004) 0.94
OPR, PC and AID: all in the PB1 family. Trends Biochem Sci (2002) 0.94
Crystal structure and mechanism of tripeptidyl activity of prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis. J Mol Biol (2006) 0.94
Effect of taurine and potential interactions with caffeine on cardiovascular function. Amino Acids (2014) 0.94
Correlation of vulnerable coronary plaques to sudden cardiac events. Lessons from a myocardial infarction-prone animal model (the WHHLMI rabbit). J Atheroscler Thromb (2004) 0.93