Published in Nature on April 26, 1990
Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule. J Cell Biol (1991) 3.91
Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice. Neuron (2008) 2.95
Characterization of a novel peripheral nervous system myelin protein (PMP-22/SR13). J Cell Biol (1992) 1.56
Tst-1, a member of the POU domain gene family, binds the promoter of the gene encoding the cell surface adhesion molecule P0. Mol Cell Biol (1991) 1.56
P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves. J Cell Biol (2000) 1.55
Novel E-cadherin-mediated adhesion in peripheral nerve: Schwann cell architecture is stabilized by autotypic adherens junctions. J Cell Biol (1995) 1.49
Structure of a new nervous system glycoprotein, Nr-CAM, and its relationship to subgroups of neural cell adhesion molecules. J Cell Biol (1991) 1.45
The receptor tyrosine kinase ARK mediates cell aggregation by homophilic binding. Mol Cell Biol (1995) 1.36
Epithelial V-like antigen (EVA), a novel member of the immunoglobulin superfamily, expressed in embryonic epithelia with a potential role as homotypic adhesion molecule in thymus histogenesis. J Cell Biol (1998) 1.28
Homophilic adhesion between Ig superfamily carcinoembryonic antigen molecules involves double reciprocal bonds. J Cell Biol (1993) 1.26
Evolution of a neuroprotective function of central nervous system myelin. J Cell Biol (2006) 1.25
Myelin/oligodendrocyte glycoprotein is a member of a subset of the immunoglobulin superfamily encoded within the major histocompatibility complex. Proc Natl Acad Sci U S A (1993) 1.13
The erbB2 gene is required for the development of terminally differentiated spinal cord oligodendrocytes. J Cell Biol (2001) 1.10
Homophilic and heterophilic binding activities of Nr-CAM, a nervous system cell adhesion molecule. J Cell Biol (1992) 1.05
MpzR98C arrests Schwann cell development in a mouse model of early-onset Charcot-Marie-Tooth disease type 1B. Brain (2012) 1.04
Schwann cell myelination requires timely and precise targeting of P(0) protein. J Cell Biol (2000) 1.03
Protein zero, a nervous system adhesion molecule, triggers epithelial reversion in host carcinoma cells. J Cell Biol (1995) 1.02
The dual origin of the peripheral olfactory system: placode and neural crest. Mol Brain (2011) 1.02
Molecular anatomy and genetics of myelin proteins in the peripheral nervous system. J Anat (1995) 1.02
Epitope-tagged P(0) glycoprotein causes Charcot-Marie-Tooth-like neuropathy in transgenic mice. J Cell Biol (2000) 1.01
Animal models for inherited peripheral neuropathies. J Anat (1997) 1.00
The cytoplasmic domain of the myelin P0 protein influences the adhesive interactions of its extracellular domain. J Cell Biol (1994) 0.99
Mutations in the cytoplasmic domain of P0 reveal a role for PKC-mediated phosphorylation in adhesion and myelination. J Cell Biol (2001) 0.98
L-MPZ, a novel isoform of myelin P0, is produced by stop codon readthrough. J Biol Chem (2012) 0.98
Homophilic adhesion of the myelin P0 protein requires glycosylation of both molecules in the homophilic pair. J Cell Biol (1993) 0.96
Dominant-negative effect on adhesion by myelin Po protein truncated in its cytoplasmic domain. J Cell Biol (1996) 0.91
A soluble form of the F3 neuronal cell adhesion molecule promotes neurite outgrowth. J Cell Biol (1992) 0.90
Clinical features and molecular modelling of novel MPZ mutations in demyelinating and axonal neuropathies. Eur J Hum Genet (2009) 0.86
Characterization of the shark myelin Po protein. Brain Behav Evol (2008) 0.82
P0 protein is required for and can induce formation of schmidt-lantermann incisures in myelin internodes. J Neurosci (2008) 0.82
Major isoform of zebrafish P0 is a 23.5 kDa myelin glycoprotein expressed in selected white matter tracts of the central nervous system. J Comp Neurol (2011) 0.82
Phosphorylation and localization of protein-zero related (PZR) in cultured endothelial cells. Endothelium (2008) 0.81
Myelin protein zero/P0 phosphorylation and function require an adaptor protein linking it to RACK1 and PKC alpha. J Cell Biol (2007) 0.81
P0S63del impedes the arrival of wild-type P0 glycoprotein to myelin in CMT1B mice. Hum Mol Genet (2011) 0.79
A novel mutation of myelin protein zero associated with an axonal form of Charcot-Marie-Tooth disease. J Neurol Neurosurg Psychiatry (2004) 0.78
Proteolipid protein cannot replace P0 protein as the major structural protein of peripheral nervous system myelin. Glia (2014) 0.76
Two novel missense mutations in the myelin protein zero gene causes Charcot-Marie-Tooth type 2 and Déjérine-Sottas syndrome. BMC Res Notes (2010) 0.75
Charcot-Marie-Tooth disease: a novel Tyr145Ser mutation in the myelin protein zero (MPZ, P0) gene causes different phenotypes in homozygous and heterozygous carriers within one family. Neurogenetics (2003) 0.75
Myelin in cartilaginous fish. Brain Res (2016) 0.75
Endoplasmic Reticulum Protein Quality Control Failure in Myelin Disorders. Front Mol Neurosci (2017) 0.75
Tracing myelin protein zero (P0) in vivo by construction of P0-GFP fusion proteins. BMC Cell Biol (2002) 0.75
GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system. Sci Rep (2017) 0.75
Four novel mutations of the myelin protein zero gene presenting as a mild and late-onset polyneuropathy. J Neurol (2010) 0.75
Monoclonal antibody to a plasma membrane antigen of neurons. Proc Natl Acad Sci U S A (1979) 4.09
Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann Neurol (2001) 4.06
Neuropathology of fragile X-associated tremor/ataxia syndrome (FXTAS). Brain (2005) 3.99
Identification of a novel aspartic protease (Asp 2) as beta-secretase. Mol Cell Neurosci (1999) 3.77
Antibody-mediated clearance of alphavirus infection from neurons. Science (1991) 3.70
A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration. Neuron (1994) 3.57
Human dystrophin expression in mdx mice after intramuscular injection of DNA constructs. Nature (1991) 3.03
An autosomal transcript in skeletal muscle with homology to dystrophin. Nature (1989) 2.91
Inhibitor of neurite outgrowth in humans. Nature (2000) 2.89
NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions. J Neurosci (2000) 2.87
Cortical demyelination in PML and MS: Similarities and differences. Neurology (2008) 2.75
NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia. Nature (2005) 2.74
Structural mosaicism on the submicron scale in the plasma membrane. Biophys J (1998) 2.50
Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons. J Neurosci (1998) 2.43
Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin. Neuron (1994) 2.29
Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins. Neuron (2000) 2.25
Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration. Mult Scler (2003) 2.24
Expression and activity of the POU transcription factor SCIP. Science (1990) 2.23
Orientation of cell-surface antigens in the lipid bilayer of lymphocyte plasma membrane. Nature (1977) 2.18
Axonal loss in the pathology of MS: consequences for understanding the progressive phase of the disease. J Neurol Sci (2003) 2.17
Oligodendrocyte population dynamics and the role of PDGF in vivo. Neuron (1998) 2.11
Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients. Ann Neurol (2000) 2.08
Basis of neurovirulence in Sindbis virus encephalomyelitis of mice. Lab Invest (1988) 2.05
Childhood ataxia with diffuse central nervous system hypomyelination. Ann Neurol (1994) 1.98
Alternative splicing generates a secreted form of N-CAM in muscle and brain. Cell (1988) 1.97
Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains. Ann Neurol (1994) 1.95
CAM-FGF receptor interactions: a model for axonal growth. Mol Cell Neurosci (1996) 1.95
Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences. Curr Opin Neurol (2001) 1.92
Neural cell adhesion molecule (NCAM) is the antigen recognized by monoclonal antibodies of similar specificity in small-cell lung carcinoma and neuroblastoma. Int J Cancer (1989) 1.85
Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels. Cell (1991) 1.85
Epithelial (E-) and placental (P-) cadherin cell adhesion molecule expression in breast carcinoma. J Pathol (1993) 1.83
Human muscle neural cell adhesion molecule (N-CAM): identification of a muscle-specific sequence in the extracellular domain. Cell (1987) 1.81
Wallerian degeneration in the peripheral nervous system: participation of both Schwann cells and macrophages in myelin degradation. J Neurocytol (1989) 1.79
Cerebral white matter changes in acquired immunodeficiency syndrome dementia: alterations of the blood-brain barrier. Ann Neurol (1993) 1.73
Deposits of amyloid beta protein in the central nervous system of transgenic mice. Science (1991) 1.69
Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation stimulated by CAMs. Neuron (1997) 1.64
Purification and expansion of human Schwann cells in vitro. Nat Med (1995) 1.63
Evidence for collapsin-1 functioning in the control of neural crest migration in both trunk and hindbrain regions. Development (1999) 1.60
A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism. Proc Natl Acad Sci U S A (1985) 1.59
P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves. J Cell Biol (2000) 1.55
Axonal loss in normal-appearing white matter in a patient with acute MS. Neurology (2001) 1.53
Regional modulation of neurofilament organization by myelination in normal axons. J Neurosci (1994) 1.49
NG2+ glial cells: a novel glial cell population in the adult brain. J Neuropathol Exp Neurol (1999) 1.49
Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy. Hum Mol Genet (1995) 1.49
IgM in a human neuropathy related to paraproteinemia binds to a carbohydrate determinant in the myelin-associated glycoprotein and to a ganglioside. Proc Natl Acad Sci U S A (1984) 1.49
Edg8/S1P5: an oligodendroglial receptor with dual function on process retraction and cell survival. J Neurosci (2005) 1.46
The p53 response to ionising radiation in adult and developing murine tissues. Oncogene (1996) 1.46
Neurite outgrowth in response to transfected N-CAM and N-cadherin reveals fundamental differences in neuronal responsiveness to CAMs. Neuron (1991) 1.46
Presence of the myelin-associated glycoprotein correlates with alterations in the periodicity of peripheral myelin. J Cell Biol (1982) 1.45
A threshold effect of the major isoforms of NCAM on neurite outgrowth. Nature (1990) 1.44
Axonal pathology in myelin disorders. J Neurocytol (2000) 1.43
Myelination in rat brain aggregating cell cultures. Neuroscience (1978) 1.42
Choline acetyltransferase activity in striatum of neonatal rats increased by nerve growth factor. Science (1985) 1.41
Neurite outgrowth in response to transfected N-CAM changes during development and is modulated by polysialic acid. Neuron (1990) 1.41
Enhanced myogenesis in NCAM-transfected mouse myoblasts. Nature (1990) 1.39
Association of GABA(B) receptors and members of the 14-3-3 family of signaling proteins. Mol Cell Neurosci (2001) 1.37
Expression of oligodendrocyte progenitor cell antigens by gliomas: implications for the histogenesis of brain tumors. Proc Natl Acad Sci U S A (1999) 1.36
Surface antigen differentiation during human myogenesis in culture. Nature (1981) 1.34
Serum antibodies to gangliosides in Guillain-Barré syndrome. Ann Neurol (1988) 1.34
Skeletal muscle neural cell adhesion molecule (N-CAM): changes in protein and mRNA species during myogenesis of muscle cell lines. J Cell Biol (1987) 1.34
Cyclic AMP-dependent protein kinase phosphorylation facilitates GABA(B) receptor-effector coupling. Nat Neurosci (2002) 1.33
Heterophilic binding of L1 on unmyelinated sensory axons mediates Schwann cell adhesion and is required for axonal survival. J Cell Biol (1999) 1.32
Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein. J Biol Chem (1998) 1.30
Calcium influx into neurons can solely account for cell contact-dependent neurite outgrowth stimulated by transfected L1. J Cell Biol (1992) 1.30
Nerve growth factor increases choline acetyltransferase activity in developing basal forebrain neurons. Brain Res (1986) 1.30
Myelin-associated glycoprotein interacts with ganglioside GT1b. A mechanism for neurite outgrowth inhibition. J Biol Chem (2001) 1.29
A soluble chimeric form of the L1 glycoprotein stimulates neurite outgrowth. Neuron (1995) 1.29
Anti-GQ1b ganglioside antibodies mediate complement-dependent destruction of the motor nerve terminal. Brain (2001) 1.28
Immunocytochemical localization of rat peripheral nervous system myelin proteins: P2 protein is not a component of all peripheral nervous system myelin sheaths. Proc Natl Acad Sci U S A (1979) 1.28
Complete sequence and in vitro expression of a tissue-specific phosphatidylinositol-linked N-CAM isoform from skeletal muscle. Development (1988) 1.26
Specific regulation of N-CAM/D2-CAM cell adhesion molecule during skeletal muscle development. EMBO J (1985) 1.25
Identification of an N-cadherin motif that can interact with the fibroblast growth factor receptor and is required for axonal growth. J Biol Chem (2001) 1.24
Isolation of human myoblasts with the fluorescence-activated cell sorter. Exp Cell Res (1988) 1.24
The cell adhesion molecule M-cadherin is specifically expressed in developing and regenerating, but not denervated skeletal muscle. Development (1993) 1.24
Neuregulin signaling through a PI3K/Akt/Bad pathway in Schwann cell survival. Mol Cell Neurosci (2001) 1.24
Detection of MHC class II-antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesions. J Neuroimmunol (1994) 1.22
Polyneuropathy and IgM monoclonal gammopathy: studies on the pathogenetic role of anti-myelin-associated glycoprotein antibody. Ann Neurol (1985) 1.20
Actin may be present on the lymphocyte surface. Proc Natl Acad Sci U S A (1978) 1.19
Immunocytochemical localization of the myelin-associated glycoprotein. Fact or artifact? J Neuroimmunol (1984) 1.19
Nerve growth factor activates Thy-1 and neurofilament gene transcription in rat PC12 cells. EMBO J (1986) 1.19
Immunocytochemical localization of P0 protein in Golgi complex membranes and myelin of developing rat Schwann cells. J Cell Biol (1981) 1.18
Tyrosine kinase inhibitors can differentially inhibit integrin-dependent and CAM-stimulated neurite outgrowth. J Cell Biol (1994) 1.16
Neurite outgrowth stimulated by neural cell adhesion molecules requires growth-associated protein-43 (GAP-43) function and is associated with GAP-43 phosphorylation in growth cones. J Neurosci (1998) 1.16
The FGFR1 inhibitor PD 173074 selectively and potently antagonizes FGF-2 neurotrophic and neurotropic effects. J Neurochem (2000) 1.15
Interferon-beta inhibits progression of relapsing-remitting experimental autoimmune encephalomyelitis. J Neuroimmunol (1996) 1.15
ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site. Mol Cell Neurosci (2000) 1.14
A role for Pak protein kinases in Schwann cell transformation. Proc Natl Acad Sci U S A (1998) 1.14
Immunocytochemical studies of quaking mice support a role for the myelin-associated glycoprotein in forming and maintaining the periaxonal space and periaxonal cytoplasmic collar of myelinating Schwann cells. J Cell Biol (1984) 1.13
Cellular determinants of the lateral mobility of neural cell adhesion molecules. Biochim Biophys Acta (1997) 1.13
Affinity-purification and characterization of caveolins from the brain: differential expression of caveolin-1, -2, and -3 in brain endothelial and astroglial cell types. Brain Res (1998) 1.13
Neutrophil infiltration, glial reaction, and neurological disease in transgenic mice expressing the chemokine N51/KC in oligodendrocytes. J Clin Invest (1996) 1.13
Negative control of Xenopus GATA-2 by activin and noggin with eventual expression in precursors of the ventral blood islands. Development (1994) 1.12
Astrocytes and Schwann cells are virus-host cells in the nervous system of rats with Borna disease. J Neuropathol Exp Neurol (1989) 1.12
Signal transduction events underlying neurite outgrowth stimulated by cell adhesion molecules. Curr Opin Neurobiol (1994) 1.10
The VASE exon downregulates the neurite growth-promoting activity of NCAM 140. Nature (1992) 1.09
Neuronal process outgrowth of human sensory neurons on monolayers of cells transfected with cDNAs for five human N-CAM isoforms. J Cell Biol (1989) 1.09
Caveolin-3 upregulation activates beta-secretase-mediated cleavage of the amyloid precursor protein in Alzheimer's disease. J Neurosci (1999) 1.08
Soluble myelin-associated glycoprotein (MAG) found in vivo inhibits axonal regeneration. Mol Cell Neurosci (1997) 1.08
Co-localization and molecular association of dystrophin with laminin at the surface of mouse and human myotubes. J Cell Sci (1992) 1.08
Nerve growth factor-induced changes in neural cell adhesion molecule (N-CAM) in PC12 cells. EMBO J (1987) 1.07