Published in J Biol Chem on October 31, 1997
Physical and functional interactions of human DNA polymerase eta with PCNA. Mol Cell Biol (2001) 2.84
Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein. Proc Natl Acad Sci U S A (1998) 2.22
The mechanism of the translocation step in DNA replication by DNA polymerase I: a computer simulation analysis. Structure (2010) 1.91
The beta clamp targets DNA polymerase IV to DNA and strongly increases its processivity. EMBO Rep (2000) 1.77
DNA polymerase fidelity: from genetics toward a biochemical understanding. Genetics (1998) 1.52
The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains. Mol Cell Biol (2005) 1.51
RPA and PCNA suppress formation of large deletion errors by yeast DNA polymerase delta. Nucleic Acids Res (2006) 1.43
The processivity factor beta controls DNA polymerase IV traffic during spontaneous mutagenesis and translesion synthesis in vivo. EMBO Rep (2001) 1.41
Insights into the replisome from the structure of a ternary complex of the DNA polymerase III alpha-subunit. J Mol Biol (2008) 1.37
The lower bound to the evolution of mutation rates. Genome Biol Evol (2011) 1.33
Spontaneous frameshift mutations in Saccharomyces cerevisiae: accumulation during DNA replication and removal by proofreading and mismatch repair activities. Genetics (2001) 1.13
Mechanism of DNA polymerase II-mediated frameshift mutagenesis. Proc Natl Acad Sci U S A (2001) 1.13
DNA polymerase fidelity: comparing direct competition of right and wrong dNTP substrates with steady state and pre-steady state kinetics. Biochemistry (2010) 1.13
Adenosine triphosphate stimulates Aquifex aeolicus MutL endonuclease activity. PLoS One (2009) 1.00
Identification of a mutant DNA polymerase delta in Saccharomyces cerevisiae with an antimutator phenotype for frameshift mutations. Genetics (2001) 0.99
A mechanism of nucleotide misincorporation during transcription due to template-strand misalignment. Mol Cell (2006) 0.96
DNA polymerases drive DNA sequencing-by-synthesis technologies: both past and present. Front Microbiol (2014) 0.95
Regulation of Mutagenic DNA Polymerase V Activation in Space and Time. PLoS Genet (2015) 0.93
Architecture of the Pol III-clamp-exonuclease complex reveals key roles of the exonuclease subunit in processive DNA synthesis and repair. EMBO J (2013) 0.92
Dpb2p, a noncatalytic subunit of DNA polymerase epsilon, contributes to the fidelity of DNA replication in Saccharomyces cerevisiae. Genetics (2008) 0.91
Localization, mobility and fidelity of retrotransposed Group II introns in rRNA genes. Nucleic Acids Res (2005) 0.90
The Y-family DNA polymerase Dpo4 uses a template slippage mechanism to create single-base deletions. J Bacteriol (2011) 0.90
Escherichia coli DNA polymerase III is responsible for the high level of spontaneous mutations in mutT strains. Mol Microbiol (2012) 0.89
Dysfunctional proofreading in the Escherichia coli DNA polymerase III core. Biochem J (2004) 0.88
UmuD(2) inhibits a non-covalent step during DinB-mediated template slippage on homopolymeric nucleotide runs. J Biol Chem (2010) 0.87
Mutagenic spectra arising from replication bypass of the 2,6-diamino-4-hydroxy-N(5)-methyl formamidopyrimidine adduct in primate cells. Chem Res Toxicol (2013) 0.85
cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and τ. Elife (2015) 0.84
Human polymerase kappa uses a template-slippage deletion mechanism, but can realign the slipped strands to favour base substitution mutations over deletions. Nucleic Acids Res (2013) 0.84
The Roles of UmuD in Regulating Mutagenesis. J Nucleic Acids (2010) 0.82
MutS and MutL are dispensable for maintenance of the genomic mutation rate in the halophilic archaeon Halobacterium salinarum NRC-1. PLoS One (2010) 0.81
Hypermutation in bacteria and other cellular systems. Philos Trans R Soc Lond B Biol Sci (2001) 0.80
Mutational effects of γ-rays and carbon ion beams on Arabidopsis seedlings. J Radiat Res (2013) 0.80
Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation. J Biol Chem (2009) 0.80
A substitution in the fingers domain of DNA polymerase δ reduces fidelity by altering nucleotide discrimination in the catalytic site. J Biol Chem (2013) 0.80
PolA1, a putative DNA polymerase I, is coexpressed with PerR and contributes to peroxide stress defenses of group A Streptococcus. J Bacteriol (2012) 0.79
DNA expansions generated by human Polμ on iterative sequences. Nucleic Acids Res (2012) 0.78
Biochemical analysis of DNA polymerase η fidelity in the presence of replication protein A. PLoS One (2014) 0.77
Mismatch repair at stop codons is directed independent of GATC methylation on the Escherichia coli chromosome. Sci Rep (2014) 0.77
Self-correcting mismatches during high-fidelity DNA replication. Nat Struct Mol Biol (2017) 0.76
Kinetic approaches to understanding the mechanisms of fidelity of the herpes simplex virus type 1 DNA polymerase. J Nucleic Acids (2010) 0.75
A molecular characterization of spontaneous frameshift mutagenesis within the trpA gene of Escherichia coli. DNA Repair (Amst) (2006) 0.75
Better living with hyper-mutation. Environ Mol Mutagen (2016) 0.75
Mutations for Worse or Better: Low-Fidelity DNA Synthesis by SOS DNA Polymerase V Is a Tightly Regulated Double-Edged Sword. Biochemistry (2016) 0.75
Single-molecule mechanochemical characterization of E. coli pol III core catalytic activity. Protein Sci (2017) 0.75
TRANSFAC: an integrated system for gene expression regulation. Nucleic Acids Res (2000) 15.70
The TRANSFAC system on gene expression regulation. Nucleic Acids Res (2001) 13.63
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell (2000) 9.13
The importance of repairing stalled replication forks. Nature (2000) 7.93
RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature (1996) 7.04
Expanding the TRANSFAC database towards an expert system of regulatory molecular mechanisms. Nucleic Acids Res (1999) 6.70
A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nat Genet (1996) 6.58
The Y-family of DNA polymerases. Mol Cell (2001) 6.49
Natural engineering principles of electron tunnelling in biological oxidation-reduction. Nature (1999) 6.38
Revealing the maximum strength in nanotwinned copper. Science (2009) 6.27
Fidelity mechanisms in DNA replication. Annu Rev Biochem (1991) 5.93
Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp. Cell (1992) 5.77
Stroke incidence among white, black, and Hispanic residents of an urban community: the Northern Manhattan Stroke Study. Am J Epidemiol (1998) 5.54
Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA. Cell (1996) 5.38
Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3) Nature (1996) 5.32
Arabidopsis auxin-resistance gene AXR1 encodes a protein related to ubiquitin-activating enzyme E1. Nature (1993) 5.22
Mechanisms of fatty acid-induced inhibition of glucose uptake. J Clin Invest (1994) 5.12
Gene delivery to skeletal muscle results in sustained expression and systemic delivery of a therapeutic protein. Proc Natl Acad Sci U S A (1996) 4.76
The TIR1 protein of Arabidopsis functions in auxin response and is related to human SKP2 and yeast grr1p. Genes Dev (1998) 4.72
A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol Cell Biol (1996) 4.47
UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V. Proc Natl Acad Sci U S A (1999) 4.24
Cdc25 cell-cycle phosphatase as a target of c-myc. Nature (1996) 4.23
Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs. Science (2013) 4.17
Comparison between DNA melting thermodynamics and DNA polymerase fidelity. Proc Natl Acad Sci U S A (1988) 4.07
The Zarit Burden Interview: a new short version and screening version. Gerontologist (2001) 3.95
Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis. Nature (2000) 3.95
Reduced naphthylphthalamic acid binding in the tir3 mutant of Arabidopsis is associated with a reduction in polar auxin transport and diverse morphological defects. Plant Cell (1997) 3.78
Development of microsatellite markers and characterization of simple sequence length polymorphism (SSLP) in rice (Oryza sativa L.). Mol Gen Genet (1996) 3.75
Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR. Nucleic Acids Res (1992) 3.74
Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading, and lesion bypass efficiencies. Methods Enzymol (1995) 3.65
CD8(+) T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons. J Exp Med (2000) 3.62
Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol Cell Biol (1998) 3.61
DNA polymerase insertion fidelity. Gel assay for site-specific kinetics. J Biol Chem (1987) 3.59
A risk of malignancy index incorporating CA 125, ultrasound and menopausal status for the accurate preoperative diagnosis of ovarian cancer. Br J Obstet Gynaecol (1990) 3.58
Effectiveness of a regional trauma system in reducing mortality from major trauma: before and after study. BMJ (1997) 3.55
Does cyclosporin increase lipoprotein(a) concentrations in renal transplant recipients? Lancet (1993) 3.54
Functionalized graphene sheets for polymer nanocomposites. Nat Nanotechnol (2008) 3.45
Nucleotide insertion kinetics opposite abasic lesions in DNA. J Biol Chem (1987) 3.41
Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase. J Biol Chem (1990) 3.38
Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme. J Biol Chem (1991) 3.37
SVM-Prot: Web-based support vector machine software for functional classification of a protein from its primary sequence. Nucleic Acids Res (2003) 3.34
Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am J Respir Cell Mol Biol (1994) 3.32
DNA polymerase III holoenzyme: structure and function of a chromosomal replicating machine. Annu Rev Biochem (1995) 3.27
ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer. EMBO J (1996) 3.22
Efficacy of a small single dose of oral dexamethasone for outpatient croup: a double blind placebo controlled clinical trial. BMJ (1996) 3.15
Regulation of CSF1 promoter by the SWI/SNF-like BAF complex. Cell (2001) 3.10
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. Proc Natl Acad Sci U S A (1994) 3.03
Requesting necropsies. BMJ (1997) 3.00
Speckle tracking methods for ultrasonic elasticity imaging using short-time correlation. IEEE Trans Ultrason Ferroelectr Freq Control (1999) 2.97
Plasma brain natriuretic peptide in assessment of acute dyspnoea. Lancet (1994) 2.96
Evolutionarily conserved sequences on human chromosome 21. Genome Res (2001) 2.95
Association between obesity and kidney disease: a systematic review and meta-analysis. Kidney Int (2007) 2.92
Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice. J Clin Invest (2001) 2.90
Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles. J Clin Invest (1992) 2.80
An information-based sequence distance and its application to whole mitochondrial genome phylogeny. Bioinformatics (2001) 2.80
Parallel genotyping of human SNPs using generic high-density oligonucleotide tag arrays. Genome Res (2000) 2.79
Testosterone dose-response relationships in healthy young men. Am J Physiol Endocrinol Metab (2001) 2.79
Studies on the biochemical basis of spontaneous mutation. II. The incorporation of a base and its analogue into DNA by wild-type, mutator and antimutator DNA polymerases. J Mol Biol (1974) 2.79
Filamentous growth of Candida albicans in response to physical environmental cues and its regulation by the unique CZF1 gene. Mol Microbiol (1999) 2.74
A clarification of transmission terms in host-microparasite models: numbers, densities and areas. Epidemiol Infect (2002) 2.69
Aerosolised pentamidine as sole therapy for Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome. Lancet (1987) 2.68
Crystal structure of the processivity clamp loader gamma (gamma) complex of E. coli DNA polymerase III. Cell (2001) 2.68
The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the beta 2-adrenergic receptor. J Biol Chem (2000) 2.67
Effects of fat on insulin-stimulated carbohydrate metabolism in normal men. J Clin Invest (1991) 2.65
Perceived discrimination and early substance abuse among American Indian children. J Health Soc Behav (2001) 2.60
Genetic evidence for the involvement of tau in progressive supranuclear palsy. Ann Neurol (1997) 2.60
Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42. J Biol Chem (1999) 2.57
A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein. Genes Dev (1993) 2.53
Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms. J Biol Chem (1979) 2.53
Trading places on DNA--a three-point switch underlies primer handoff from primase to the replicative DNA polymerase. Cell (1999) 2.51
Human CD4(+) T lymphocytes consistently respond to the latent Epstein-Barr virus nuclear antigen EBNA1. J Exp Med (2000) 2.48
The common and distinct target genes of the p53 family transcription factors. Cell Mol Life Sci (2004) 2.47
Agrobacterium-Mediated Transformation of Fusarium oxysporum: An Efficient Tool for Insertional Mutagenesis and Gene Transfer. Phytopathology (2001) 2.43
An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease. Nature (1997) 2.42
p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes. Oncogene (2001) 2.40
Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III. Cell (2001) 2.39
English language use as a risk factor for smoking initiation among Hispanic and Asian American adolescents: evidence for mediation by tobacco-related beliefs and social norms. Health Psychol (2000) 2.36
Activity of amoxicillin/clavulanate in patients with tuberculosis. Clin Infect Dis (1998) 2.35
Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA. Nature (1999) 2.35
Medically unexplained symptoms in secondary care. BMJ (2001) 2.34
Infection in social networks: using network analysis to identify high-risk individuals. Am J Epidemiol (2005) 2.31
A whole genome association study of neuroticism using DNA pooling. Mol Psychiatry (2007) 2.30
Nearest neighbor influences on DNA polymerase insertion fidelity. J Biol Chem (1989) 2.29
The General Medical Council's Performance Procedures: peer review of performance in the workplace. Med Educ (2001) 2.27
The assessment of poorly performing doctors: the development of the assessment programmes for the General Medical Council's Performance Procedures. Med Educ (2001) 2.26
ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease. Antimicrob Agents Chemother (1998) 2.23
NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation. Oncogene (2011) 2.22
Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein. Proc Natl Acad Sci U S A (1998) 2.22
Systematic review: the management of chronic diarrhoea due to bile acid malabsorption. Aliment Pharmacol Ther (2014) 2.17
Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III. Cell (1997) 2.16
The role of social networks and media receptivity in predicting age of smoking initiation: a proportional hazards model of risk and protective factors. Addict Behav (1999) 2.14
Successful treatment of primary amebic meningoencephalitis. N Engl J Med (1982) 2.14
Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase. Proc Natl Acad Sci U S A (1999) 2.14
The p53 protein is an unusually shaped tetramer that binds directly to DNA. Proc Natl Acad Sci U S A (1993) 2.11
The AXR1 and AUX1 genes of Arabidopsis function in separate auxin-response pathways. Plant J (1995) 2.11
Sliding clamps of DNA polymerases. J Mol Biol (1993) 2.11