Published in Mol Psychiatry on August 29, 2006
Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components. J Neurosci (2008) 1.80
Adaptive evolution of genes underlying schizophrenia. Proc Biol Sci (2007) 1.58
The genetics of bipolar disorder. Neuroscience (2009) 1.57
A role for white matter abnormalities in the pathophysiology of bipolar disorder. Neurosci Biobehav Rev (2009) 1.49
Specific regulation of NRG1 isoform expression by neuronal activity. J Neurosci (2011) 1.46
Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases. Neuron (2014) 1.30
A social deafferentation hypothesis for induction of active schizophrenia. Schizophr Bull (2007) 1.26
Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls. Arch Gen Psychiatry (2010) 1.24
White matter integrity, creativity, and psychopathology: disentangling constructs with diffusion tensor imaging. PLoS One (2010) 1.18
PADB: published association database. BMC Bioinformatics (2007) 1.12
Effects of schizophrenia risk variation in the NRG1 gene on NRG1-IV splicing during fetal and early postnatal human neocortical development. Am J Psychiatry (2014) 1.09
Evidence of missense mutations on the neuregulin 1 gene affecting function of prepulse inhibition. Biol Psychiatry (2007) 1.06
Genetic variants in the ErbB4 gene are associated with white matter integrity. Psychiatry Res (2011) 0.96
Mechanisms of neuregulin action. Novartis Found Symp (2008) 0.95
Neuregulin 1 genotype and schizophrenia. Schizophr Bull (2007) 0.95
Discovery, validation and characterization of Erbb4 and Nrg1 haplotypes using data from three genome-wide association studies of schizophrenia. PLoS One (2013) 0.90
Measurement and comparison of serum neuregulin 1 immunoreactivity in control subjects and patients with schizophrenia: an influence of its genetic polymorphism. J Neural Transm (Vienna) (2010) 0.90
Synaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia. Front Synaptic Neurosci (2014) 0.87
Impact of neuregulin-1 on the pathophysiology of schizophrenia in human post-mortem studies. Eur Arch Psychiatry Clin Neurosci (2008) 0.87
Biomarkers of bipolar disorder: specific or shared with schizophrenia? Front Biosci (Elite Ed) (2013) 0.86
Association study of neuregulin-1 gene polymorphisms in a North Indian schizophrenia sample. Schizophr Res (2013) 0.86
Family-based association study of Neuregulin 1 with psychotic bipolar disorder. Am J Med Genet B Neuropsychiatr Genet (2009) 0.85
Schizophrenia-related neuregulin-1 single-nucleotide polymorphisms lead to deficient smooth eye pursuit in a large sample of young men. Schizophr Bull (2009) 0.83
Lack of association to a NRG1 missense polymorphism in schizophrenia or bipolar disorder in a Costa Rican population. Schizophr Res (2011) 0.83
Nature and nurture in neuropsychiatric genetics: where do we stand? Dialogues Clin Neurosci (2010) 0.82
Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models. Front Psychiatry (2015) 0.79
Neurotransmission and bipolar disorder: a systematic family-based association study. Am J Med Genet B Neuropsychiatr Genet (2008) 0.79
Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Hum Mol Genet (2016) 0.79
White matter microstructure alterations in bipolar disorder. Funct Neurol (2012) 0.78
Evidence for single nucleotide polymorphisms and their association with bipolar disorder. Neuropsychiatr Dis Treat (2013) 0.78
Copy variations in schizophrenia and bipolar disorder. Cytogenet Genome Res (2009) 0.78
Neuregulin 1 and age of onset in the major psychoses. J Neural Transm (Vienna) (2009) 0.77
Analysis of a promoter polymorphism in the SMDF neuregulin 1 isoform in Schizophrenia. Neuropsychobiology (2009) 0.77
A gene trap mutagenesis screen for genes underlying cellular response to the mood stabilizer lithium. J Cell Mol Med (2013) 0.77
Neurobehavioral Differences Between Mice Receiving Distinct Neuregulin Variants as Neonates; Impact on Sensitivity to MK-801. Curr Mol Med (2015) 0.77
Genetic association of the EGR2 gene with bipolar disorder in Korea. Exp Mol Med (2012) 0.76
Significant correlation between openness personality in normal subjects and brain myelin mapping with T1/T2-weighted MR imaging. Heliyon (2017) 0.75
BACE1-Dependent Neuregulin-1 Signaling: An Implication for Schizophrenia. Front Mol Neurosci (2017) 0.75
Forebrain-specific ablation of phospholipase Cγ1 causes manic-like behavior. Mol Psychiatry (2017) 0.75
Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet (2000) 7.16
Whole-genome association study of bipolar disorder. Mol Psychiatry (2008) 6.80
Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. Am J Hum Genet (2001) 4.77
Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Mol Psychiatry (2011) 4.16
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Mol Psychiatry (2008) 3.85
The DISC locus in psychiatric illness. Mol Psychiatry (2007) 3.46
SUSPECTS: enabling fast and effective prioritization of positional candidates. Bioinformatics (2006) 2.96
Prognostic significance of anaplastic lymphoma kinase (ALK) protein expression in adults with anaplastic large cell lymphoma. Blood (1999) 2.95
Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned. Mol Psychiatry (2010) 2.95
Anaplastic lymphoma kinase (ALK) expression in the inflammatory myofibroblastic tumor: a comparative immunohistochemical study. Am J Surg Pathol (2001) 2.80
WWOX: a candidate tumor suppressor gene involved in multiple tumor types. Proc Natl Acad Sci U S A (2001) 2.79
Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nat Genet (2001) 2.55
Splinkerettes--improved vectorettes for greater efficiency in PCR walking. Nucleic Acids Res (1995) 2.51
ALK-positive lymphoma: a single disease with a broad spectrum of morphology. Blood (1998) 2.41
The emerging normal and disease-related roles of anaplastic lymphoma kinase. Cell Mol Life Sci (2004) 2.19
Anaplastic lymphoma kinase proteins in growth control and cancer. J Cell Physiol (2004) 2.19
Case-control study of neurocognitive function in euthymic patients with bipolar disorder: an association with mania. Br J Psychiatry (2002) 2.11
Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis. Mol Cell Biol (1997) 2.04
Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32). Nat Genet (1999) 1.96
Lung clearance index is a sensitive, repeatable and practical measure of airways disease in adults with cystic fibrosis. Thorax (2007) 1.93
Development and geometry of isotropic and directional shrinkage-crack patterns. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics (2000) 1.88
Retrovirus-mediated gene transfer of NPM-ALK causes lymphoid malignancy in mice. Blood (1997) 1.83
A new subtype of large B-cell lymphoma expressing the ALK kinase and lacking the 2; 5 translocation. Blood (1997) 1.82
Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia. Mol Psychiatry (2001) 1.81
Expression of the ALK tyrosine kinase gene in neuroblastoma. Am J Pathol (2000) 1.75
High-resolution localization of 69 potential human zinc finger protein genes: a number are clustered. Genomics (1992) 1.74
Fusion of the ALK gene to the clathrin heavy chain gene, CLTC, in inflammatory myofibroblastic tumor. Am J Pathol (2001) 1.72
The effects of a neuregulin 1 variant on white matter density and integrity. Mol Psychiatry (2007) 1.68
Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity. Mol Cell Biol (1998) 1.68
A locus for bipolar affective disorder on chromosome 4p. Nat Genet (1996) 1.67
The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1. Oncogene (1996) 1.65
Translocations involving anaplastic lymphoma kinase (ALK). Oncogene (2001) 1.61
Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis. Cancer Res (2001) 1.60
Candidate gene polymorphisms for behavioural adaptations during urbanization in blackbirds. Mol Ecol (2013) 1.59
A demonstration using mouse models that successful gene therapy for cystic fibrosis requires only partial gene correction. Gene Ther (1996) 1.49
Disruption of the neuronal PAS3 gene in a family affected with schizophrenia. J Med Genet (2003) 1.46
Automation of genetic linkage analysis using fluorescent microsatellite markers. Genomics (1994) 1.43
Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population. Mol Psychiatry (2005) 1.41
DNA restriction fragment length polymorphisms as markers of familial coronary heart disease. Lancet (1989) 1.40
A 700-kb physical map of a region of 16q23.2 homozygously deleted in multiple cancers and spanning the common fragile site FRA16D. Cancer Res (2000) 1.39
Lung disease in the cystic fibrosis mouse exposed to bacterial pathogens. Nat Genet (1995) 1.37
Disrupted in Schizophrenia 1 (DISC1) is a multicompartmentalized protein that predominantly localizes to mitochondria. Mol Cell Neurosci (2004) 1.35
Control of the flux in the arginine pathway of Neurospora crassa. Modulations of enzyme activity and concentration. Biochem J (1981) 1.35
Chromosomal assignment and genomic structure of Il15. Genomics (1995) 1.31
Identification of polymorphisms within Disrupted in Schizophrenia 1 and Disrupted in Schizophrenia 2, and an investigation of their association with schizophrenia and bipolar affective disorder. Psychiatr Genet (2001) 1.30
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science (1995) 1.27
Auditory P300 and eye tracking dysfunction in schizophrenic pedigrees. Arch Gen Psychiatry (1991) 1.27
Interacting haplotypes at the NPAS3 locus alter risk of schizophrenia and bipolar disorder. Mol Psychiatry (2008) 1.27
Peripheral nerve-conduction block by high muscle-compartment pressure. J Bone Joint Surg Am (1979) 1.26
Molecular analysis of chromosome 11 deletions in aniridia-Wilms tumor syndrome. Proc Natl Acad Sci U S A (1985) 1.22
CFTR and calcium-activated chloride currents in pancreatic duct cells of a transgenic CF mouse. Am J Physiol (1994) 1.20
Presence of multiple functional polyadenylation signals and a single nucleotide polymorphism in the 3' untranslated region of the human serotonin transporter gene. J Neurochem (1999) 1.18
Molecular and physical arrangements of human DNA in HRAS1-selected, chromosome-mediated transfectants. Mol Cell Biol (1986) 1.17
Quantitation of skeletal-muscle necrosis in a model compartment syndrome. J Bone Joint Surg Am (1981) 1.17
Control of the flux in the arginine pathway of Neurospora crassa. The flux from citrulline to arginine. Biochem J (1980) 1.16
Association between genotype at an exonic SNP in DISC1 and normal cognitive aging. Neurosci Lett (2005) 1.15
Inclusion of cholesterol in DOTAP transfection complexes increases the delivery of DNA to cells in vitro in the presence of serum. Gene Ther (1998) 1.14
'Pfropfschizophrenie' revisited. Schizophrenia in people with mild learning disability. Br J Psychiatry (1998) 1.14
Rethinking the genetic architecture of schizophrenia. Psychol Med (2010) 1.13
Sendai virus-mediated CFTR gene transfer to the airway epithelium. Gene Ther (2007) 1.13
Disruption of a brain transcription factor, NPAS3, is associated with schizophrenia and learning disability. Am J Med Genet B Neuropsychiatr Genet (2005) 1.13
Cystic fibrosis mice carrying the missense mutation G551D replicate human genotype-phenotype correlations. EMBO J (1996) 1.13
Cytogenetic and genetic evidence supports a role for the kainate-type glutamate receptor gene, GRIK4, in schizophrenia and bipolar disorder. Mol Psychiatry (2006) 1.12
Role of signal transducer and activator of transcription 5 in nucleophosmin/ anaplastic lymphoma kinase-mediated malignant transformation of lymphoid cells. Cancer Res (2001) 1.12
Adenoviral augmentation of elafin protects the lung against acute injury mediated by activated neutrophils and bacterial infection. J Immunol (2001) 1.11
Mutational screening and association study of glutamate decarboxylase 1 as a candidate susceptibility gene for bipolar affective disorder and schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2005) 1.11
HRAS1-selected chromosome transfer generates markers that colocalize aniridia- and genitourinary dysplasia-associated translocation breakpoints and the Wilms tumor gene within band 11p13. Proc Natl Acad Sci U S A (1987) 1.11
Activity of TNF-related apoptosis-inducing ligand (TRAIL) in haematological malignancies. Br J Haematol (1997) 1.10
Nucleolar localization of the nucleophosmin-anaplastic lymphoma kinase is not required for malignant transformation. Cancer Res (1998) 1.10
Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung. Gene Ther (2011) 1.10
A genome scan and follow-up study identify a bipolar disorder susceptibility locus on chromosome 1q42. Mol Psychiatry (2004) 1.08