Published in Proc Natl Acad Sci U S A on August 31, 2006
Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells. Cell Stem Cell (2009) 4.43
Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell (2008) 3.62
Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation. Proc Natl Acad Sci U S A (2007) 2.25
Wnt-related molecules and signaling pathway equilibrium in hematopoiesis. Cell Stem Cell (2009) 2.00
HMGB1 in health and disease. Mol Aspects Med (2014) 1.67
Transcription factor Oct1 is a somatic and cancer stem cell determinant. PLoS Genet (2012) 1.15
Hematopoietic stem cell function requires 12/15-lipoxygenase-dependent fatty acid metabolism. Blood (2010) 1.14
Gene expression profiling and chromatin immunoprecipitation identify DBN1, SETMAR and HIG2 as direct targets of SOX11 in mantle cell lymphoma. PLoS One (2010) 1.08
Comparative transcriptional profiling of the axolotl limb identifies a tripartite regeneration-specific gene program. PLoS One (2013) 1.04
miRNA-mRNA integrative analysis in primary myelofibrosis CD34+ cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis. Blood (2014) 0.93
Nucleocytoplasmic distribution of the Arabidopsis chromatin-associated HMGB2/3 and HMGB4 proteins. Plant Physiol (2010) 0.91
Bmi1 reprograms CML B-lymphoid progenitors to become B-ALL-initiating cells. Blood (2011) 0.87
The role of microRNAs in skeletal muscle health and disease. Front Biosci (Landmark Ed) (2015) 0.84
HMGB factors are required for posterior digit development through integrating signaling pathway activities. Dev Dyn (2011) 0.84
The epigenetics of adult (somatic) stem cells. Crit Rev Eukaryot Gene Expr (2008) 0.83
KIT receptor gain-of-function in hematopoiesis enhances stem cell self-renewal and promotes progenitor cell expansion. Stem Cells (2013) 0.82
Increased expression of HMGB3: a novel independent prognostic marker of worse outcome in patients with esophageal squamous cell carcinoma. Int J Clin Exp Pathol (2015) 0.81
Single-cell analyses of X Chromosome inactivation dynamics and pluripotency during differentiation. Genome Res (2016) 0.81
High mobility group-box 3 overexpression is associated with poor prognosis of resected gastric adenocarcinoma. World J Gastroenterol (2012) 0.79
Prioritizing genes for X-linked diseases using population exome data. Hum Mol Genet (2014) 0.75
miR-494-3p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6. Oncotarget (2017) 0.75
Differences of immune disorders between Alzheimer's disease and breast cancer based on transcriptional regulation. PLoS One (2017) 0.75
The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol (2004) 24.63
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet (2000) 21.52
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med (1996) 17.51
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature (2000) 16.75
A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature (2003) 12.81
Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell (1997) 12.60
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med (2004) 11.29
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development (1999) 9.82
Biology of hematopoietic stem cells and progenitors: implications for clinical application. Annu Rev Immunol (2002) 7.78
The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice. Nat Genet (1999) 4.77
Specific recognition of cruciform DNA by nuclear protein HMG1. Science (1989) 4.44
Structural features of the HMG chromosomal proteins and their genes. Biochim Biophys Acta (1990) 3.55
Phenotypic and functional changes induced at the clonal level in hematopoietic stem cells after 5-fluorouracil treatment. Blood (1997) 2.84
Specific binding of chromosomal protein HMG1 to DNA damaged by the anticancer drug cisplatin. Science (1992) 2.79
High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors. EMBO J (1995) 2.48
The dishevelled protein is modified by wingless signaling in Drosophila. Genes Dev (1995) 2.46
HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation. EMBO J (1996) 2.09
HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation. Exp Hematol (2001) 1.81
Vascular bed-specific expression of an endothelial cell gene is programmed by the tissue microenvironment. J Cell Biol (1997) 1.74
Reduced fertility and spermatogenesis defects in mice lacking chromosomal protein Hmgb2. Development (2001) 1.63
Pluripotent hematopoietic stem cells contain high levels of mRNA for c-kit, GATA-2, p45 NF-E2, and c-myb and low levels or no mRNA for c-fms and the receptors for granulocyte colony-stimulating factor and interleukins 5 and 7. Proc Natl Acad Sci U S A (1995) 1.58
Characterization of mouse dishevelled (Dvl) proteins in Wnt/Wingless signaling pathway. J Biol Chem (1999) 1.41
Hmg4, a new member of the Hmg1/2 gene family. Genomics (1998) 1.37
Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation. Blood (2003) 1.20
Net increase of pluripotential hematopoietic precursors in suspension culture in response to IL-1 and IL-3. J Immunol (1989) 1.09
ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status. Blood (2004) 1.06
Hmgb3 deficiency deregulates proliferation and differentiation of common lymphoid and myeloid progenitors. Blood (2004) 1.01
Accelerated recovery of peripheral blood cell counts in mice transplanted with in vitro cytokine-expanded hematopoietic progenitors. Exp Hematol (1992) 0.96
Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome. PLoS Genet (2007) 5.93
Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase. Immunity (2009) 2.51
Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation. Proc Natl Acad Sci U S A (2007) 2.25
A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia. Blood (2010) 1.88
Bone marrow stem cells regenerate infarcted myocardium. Pediatr Transplant (2003) 1.66
High-efficiency recovery of functional hematopoietic progenitor and stem cells from human cord blood cryopreserved for 15 years. Proc Natl Acad Sci U S A (2003) 1.60
Requirements for selection of conventional and innate T lymphocyte lineages. Immunity (2007) 1.59
Ribosomal protein gene deletions in Diamond-Blackfan anemia. Blood (2011) 1.57
An experimental system for the evaluation of retroviral vector design to diminish the risk for proto-oncogene activation. Blood (2007) 1.57
Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation. Blood (2011) 1.50
Adducin forms a bridge between the erythrocyte membrane and its cytoskeleton and regulates membrane cohesion. Blood (2009) 1.42
Failure of terminal erythroid differentiation in EKLF-deficient mice is associated with cell cycle perturbation and reduced expression of E2F2. Mol Cell Biol (2008) 1.42
Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites. Genome Res (2012) 1.37
Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development. Blood (2014) 1.34
Alterations in expression and chromatin configuration of the alpha hemoglobin-stabilizing protein gene in erythroid Kruppel-like factor-deficient mice. Mol Cell Biol (2006) 1.26
Major erythrocyte membrane protein genes in EKLF-deficient mice. Exp Hematol (2006) 1.23
Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation. Blood (2003) 1.20
Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells. J Exp Med (2014) 1.16
Regulation of hematopoiesis and the hematopoietic stem cell niche by Wnt signaling pathways. Cell Res (2007) 1.14
Reversion mutations in patients with leukocyte adhesion deficiency type-1 (LAD-1). Blood (2007) 1.09
Side population cells derived from adult human liver generate hepatocyte-like cells in vitro. Dig Dis Sci (2005) 1.02
An 11-amino acid beta-hairpin loop in the cytoplasmic domain of band 3 is responsible for ankyrin binding in mouse erythrocytes. Proc Natl Acad Sci U S A (2007) 1.02
Hmgb3 deficiency deregulates proliferation and differentiation of common lymphoid and myeloid progenitors. Blood (2004) 1.01
beta-Catenin expression in the bone marrow microenvironment is required for long-term maintenance of primitive hematopoietic cells. Stem Cells (2009) 0.97
An insulator with barrier-element activity promotes alpha-spectrin gene expression in erythroid cells. Blood (2008) 0.93
Mutation of a barrier insulator in the human ankyrin-1 gene is associated with hereditary spherocytosis. J Clin Invest (2010) 0.93
Exploiting pre-rRNA processing in Diamond Blackfan anemia gene discovery and diagnosis. Am J Hematol (2014) 0.93
Improved transduction of human sheep repopulating cells by retrovirus vectors pseudotyped with feline leukemia virus type C or RD114 envelopes. Blood (2005) 0.91
Sequences downstream of the erythroid promoter are required for high level expression of the human alpha-spectrin gene. J Biol Chem (2004) 0.89
Erythroid expression of the human alpha-spectrin gene promoter is mediated by GATA-1- and NF-E2-binding proteins. J Biol Chem (2002) 0.88
Sensitive quantification of mosaicism using high density SNP arrays and the cumulative distribution function. Mol Genet Metab (2011) 0.86
GATA-1 and Oct-1 are required for expression of the human alpha-hemoglobin-stabilizing protein gene. J Biol Chem (2005) 0.86
Defective inhibition of B-cell proliferation by Wiskott-Aldrich syndrome protein-deficient regulatory T cells. Blood (2011) 0.85
Mutations in the murine erythroid alpha-spectrin gene alter spectrin mRNA and protein levels and spectrin incorporation into the red blood cell membrane skeleton. Blood (2002) 0.84
Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q- syndrome. Blood (2013) 0.84
Transcription factor zinc finger and BTB domain 1 is essential for lymphocyte development. J Immunol (2012) 0.83
A dinucleotide deletion in the ankyrin promoter alters gene expression, transcription initiation and TFIID complex formation in hereditary spherocytosis. Hum Mol Genet (2005) 0.83
A tissue-specific chromatin loop activates the erythroid ankyrin-1 promoter. Blood (2012) 0.80
Drug selection with paclitaxel restores expression of linked IL-2 receptor gamma -chain and multidrug resistance (MDR1) transgenes in canine bone marrow. Proc Natl Acad Sci U S A (2002) 0.80
Genome-wide detection of a TFIID localization element from an initial human disease mutation. Nucleic Acids Res (2010) 0.79
A somatic cell defect is associated with the onset of neurological symptoms in a lysosomal storage disease. Mol Genet Metab (2013) 0.77
Functional analysis of a novel cis-acting regulatory region within the human ankyrin gene (ANK-1) promoter. Mol Cell Biol (2010) 0.76
The third conference on hematopoietic stem cell gene therapy: biology and technology. Mol Ther (2002) 0.75