Published in Blood on November 18, 2011
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STAT5 signaling is required for the efficient induction and maintenance of CML in mice. Blood (2006) 1.63
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Hmgb3 regulates the balance between hematopoietic stem cell self-renewal and differentiation. Proc Natl Acad Sci U S A (2006) 1.22
Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1. Mol Cell (2003) 1.20
Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis. Leukemia (2008) 1.20
The polycomb group BMI1 gene is a molecular marker for predicting prognosis of chronic myeloid leukemia. Blood (2007) 1.17
Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo. Blood (2010) 1.13
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BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34+ cells. Blood (2010) 1.06
MEK1/2 inhibitors sensitize Bcr/Abl+ human leukemia cells to the dual Abl/Src inhibitor BMS-354/825. Blood (2007) 1.05
Ectopic expression of PAX5 promotes maintenance of biphenotypic myeloid progenitors coexpressing myeloid and B-cell lineage-associated genes. Blood (2007) 1.03
Hmgb3 deficiency deregulates proliferation and differentiation of common lymphoid and myeloid progenitors. Blood (2004) 1.01
Differential interaction and activation of Rho family GTPases by p210bcr-abl and p190bcr-abl. Oncogene (2003) 1.01
The RhoGEF domain of p210 Bcr-Abl activates RhoA and is required for transformation. Oncogene (2007) 1.00
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Signaling and cytoskeletal requirements in erythroblast enucleation. Blood (2012) 2.05
Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. Cancer Cell (2008) 1.86
Stem cell collection and gene transfer in Fanconi anemia. Mol Ther (2007) 1.81
Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow. Proc Natl Acad Sci U S A (2007) 1.74
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Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. Nat Med (2012) 1.58
FIP1L1/PDGFRalpha synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome. Blood (2008) 1.53
Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms. Blood (2013) 1.50
A rapid method for retrovirus-mediated identification of complementation groups in Fanconi anemia patients. Mol Ther (2005) 1.48
Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus. PLoS One (2009) 1.40
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Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development. Blood (2008) 1.37
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Rho GTPases and regulation of hematopoietic stem cell localization. Methods Enzymol (2008) 1.33
Cdc42 critically regulates the balance between myelopoiesis and erythropoiesis. Blood (2007) 1.28
Tissue inhibitor of metalloproteinase-3 via oncolytic herpesvirus inhibits tumor growth and vascular progenitors. Cancer Res (2008) 1.24
Inhibition of RhoA GTPase activity enhances hematopoietic stem and progenitor cell proliferation and engraftment. Blood (2006) 1.19
Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization. Nat Med (2010) 1.16
Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential. Cell Stem Cell (2008) 1.15
Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo. Blood (2010) 1.13
Rac1 is essential for intraembryonic hematopoiesis and for the initial seeding of fetal liver with definitive hematopoietic progenitor cells. Blood (2007) 1.10
Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity. J Clin Invest (2013) 1.08
Atypical protein kinase C (aPKCzeta and aPKClambda) is dispensable for mammalian hematopoietic stem cell activity and blood formation. Proc Natl Acad Sci U S A (2011) 1.07
Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors. Blood (2012) 1.05
Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition. Acta Neuropathol (2012) 1.03
Rosiglitazone treatment of type 2 diabetic db/db mice attenuates urinary albumin and angiotensin converting enzyme 2 excretion. PLoS One (2013) 1.03
Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells. Proc Natl Acad Sci U S A (2012) 0.99
Perinatal or adult Nf1 inactivation using tamoxifen-inducible PlpCre each cause neurofibroma formation. Cancer Res (2011) 0.98
The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease. Blood (2006) 0.97
Bone marrow connexin-43 expression is critical for hematopoietic regeneration after chemotherapy. Cell Commun Adhes (2006) 0.95
Mouse gene targeting reveals an essential role of mTOR in hematopoietic stem cell engraftment and hematopoiesis. Haematologica (2013) 0.94
Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival. Blood (2012) 0.92
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In vivo viability of stored red blood cells derived from riboflavin plus ultraviolet light-treated whole blood. Transfusion (2011) 0.88
R-Ras and Rac GTPase cross-talk regulates hematopoietic progenitor cell migration, homing, and mobilization. J Biol Chem (2011) 0.87
Evaluation of overnight hold of whole blood at room temperature before component processing: effect of red blood cell (RBC) additive solutions on in vitro RBC measures. Transfusion (2011) 0.87
Children are not little adults: just ask their hematopoietic stem cells. J Clin Invest (2006) 0.86
Fanca-/- hematopoietic stem cells demonstrate a mobilization defect which can be overcome by administration of the Rac inhibitor NSC23766. Haematologica (2009) 0.86
RhoA GTPase controls cytokinesis and programmed necrosis of hematopoietic progenitors. J Exp Med (2013) 0.85
Leukaemia: niche retreats for stem cells. Nature (2006) 0.85
Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells. J Clin Invest (2015) 0.84
Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells. Immunol Rev (2013) 0.83
FIP1L1/PDGFR alpha-associated systemic mastocytosis. Int Arch Allergy Immunol (2010) 0.82
Evaluation of the overnight hold of whole blood at room temperature, before component processing: platelets (PLTs) from PLT-rich plasma. Transfusion (2011) 0.82
Stem cell mobilization by beta2-agonists. Nat Med (2006) 0.81
Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature. Cell Rep (2013) 0.81
A randomized controlled trial evaluating recovery and survival of 6% dimethyl sulfoxide-frozen autologous platelets in healthy volunteers. Transfusion (2012) 0.79
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In vitro and in vivo evaluation of LEUKOSEP HRC-600-C leukoreduction filtration system for red cells. Transfusion (2006) 0.77
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Lack of communication rusts and ages stem cells. Cell Cycle (2012) 0.76
Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells. EMBO J (2017) 0.75
The bioequivalence of frozen plasma prepared from whole blood held overnight at room temperature compared to fresh-frozen plasma prepared within eight hours of collection. Transfusion (2014) 0.75
A conundrum in mammalian hematopoietic stem cell polarity. Cell Cycle (2011) 0.75