Published in N Engl J Med on September 07, 2006
Vitamins C and E to prevent complications of pregnancy-associated hypertension. N Engl J Med (2010) 3.81
Vitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects. PLoS One (2010) 1.92
Vitamin C: a concentration-function approach yields pharmacology and therapeutic discoveries. Adv Nutr (2011) 1.45
Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice. J Clin Invest (2010) 1.33
Vitamin C: the known and the unknown and Goldilocks. Oral Dis (2016) 0.82
Oxidative stress in pregnancy and reproduction. Obstet Med (2016) 0.75
Vitamins C and E and the risks of preeclampsia and perinatal complications. N Engl J Med (2006) 4.27
Antioxidants and the prevention of preeclampsia--unresolved issues. N Engl J Med (2006) 1.17
Beyond prejudice: are negative evaluations the problem and is getting us to like one another more the solution? Behav Brain Sci (2012) 18.61
Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer. J Natl Cancer Inst (2002) 4.33
Vitamin C pharmacokinetics: implications for oral and intravenous use. Ann Intern Med (2004) 4.30
Effect of a decision aid on knowledge and treatment decision making for breast cancer surgery: a randomized trial. JAMA (2004) 4.18
Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr (2003) 3.34
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Proc Natl Acad Sci U S A (2005) 3.30
Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival. Nat Med (2002) 2.90
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo. Proc Natl Acad Sci U S A (2007) 2.71
Helping patients make informed choices: a randomized trial of a decision aid for adjuvant chemotherapy in lymph node-negative breast cancer. J Natl Cancer Inst (2003) 2.51
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice. Proc Natl Acad Sci U S A (2008) 2.50
Major contribution of tubular secretion to creatinine clearance in mice. Kidney Int (2009) 2.46
The Kitty Genovese murder and the social psychology of helping: the parable of the 38 witnesses. Am Psychol (2007) 2.23
Randomized trial of high-dose chemotherapy with autologous peripheral-blood stem-cell support compared with standard-dose chemotherapy in women with metastatic breast cancer: NCIC MA.16. J Clin Oncol (2007) 2.15
Oxalic acid excretion after intravenous ascorbic acid administration. Metabolism (2009) 2.14
Randomized trial comparing two fractionation schedules for patients with localized prostate cancer. J Clin Oncol (2005) 2.06
Warfarin dose assessment every 4 weeks versus every 12 weeks in patients with stable international normalized ratios: a randomized trial. Ann Intern Med (2011) 1.98
Vitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects. PLoS One (2010) 1.92
High-dose parenteral ascorbate enhanced chemosensitivity of ovarian cancer and reduced toxicity of chemotherapy. Sci Transl Med (2014) 1.91
Clinical practice guidelines for the care and treatment of breast cancer: follow-up after treatment for breast cancer (summary of the 2005 update). CMAJ (2005) 1.89
Human adrenal glands secrete vitamin C in response to adrenocorticotrophic hormone. Am J Clin Nutr (2007) 1.60
Mechanisms of ascorbate-induced cytotoxicity in pancreatic cancer. Clin Cancer Res (2010) 1.57
Randomized trial comparing iridium implant plus external-beam radiation therapy with external-beam radiation therapy alone in node-negative locally advanced cancer of the prostate. J Clin Oncol (2005) 1.54
Coverage with evidence development: the Ontario experience. Int J Technol Assess Health Care (2011) 1.53
Inhibition of the intestinal glucose transporter GLUT2 by flavonoids. FASEB J (2006) 1.53
Clinical practice guidelines for the care and treatment of breast cancer: 15. Treatment for women with stage III or locally advanced breast cancer. CMAJ (2004) 1.51
Using administrative databases to measure waiting times for patients undergoing major cancer surgery in Ontario, 1993-2000. Can J Surg (2005) 1.49
Clinical practice guidelines for the care and treatment of breast cancer: 16. Locoregional post-mastectomy radiotherapy. CMAJ (2004) 1.46
Central venous catheter care for the patient with cancer: American Society of Clinical Oncology clinical practice guideline. J Clin Oncol (2013) 1.46
Vitamin C: a concentration-function approach yields pharmacology and therapeutic discoveries. Adv Nutr (2011) 1.45
Intravenously administered vitamin C as cancer therapy: three cases. CMAJ (2006) 1.43
Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion. Mol Biol Cell (2007) 1.41
Incidence and prognostic impact of amenorrhea during adjuvant therapy in high-risk premenopausal breast cancer: analysis of a National Cancer Institute of Canada Clinical Trials Group Study--NCIC CTG MA.5. J Clin Oncol (2005) 1.40
Phase I evaluation of intravenous ascorbic acid in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer. PLoS One (2012) 1.35
Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice. J Clin Invest (2010) 1.33
Comparison of the genomic structure and variation in the two human sodium-dependent vitamin C transporters, SLC23A1 and SLC23A2. Hum Genet (2004) 1.27
Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer. Free Radic Biol Med (2011) 1.27
Lessons learned from the Decision Board: a unique and evolving decision aid. Health Expect (2000) 1.25
6-Bromo-6-deoxy-L-ascorbic acid: an ascorbate analog specific for Na+-dependent vitamin C transporter but not glucose transporter pathways. J Biol Chem (2004) 1.16
Genomic and functional analysis of the sodium-dependent vitamin C transporter SLC23A1-SVCT1. Genes Nutr (2007) 1.16
Venous thrombosis in cancer patients: insights from the FRONTLINE survey. Oncologist (2003) 1.13
Flavonoid inhibition of sodium-dependent vitamin C transporter 1 (SVCT1) and glucose transporter isoform 2 (GLUT2), intestinal transporters for vitamin C and Glucose. J Biol Chem (2002) 1.13
Influence of hospital characteristics on operative death and survival of patients after major cancer surgery in Ontario. Can J Surg (2006) 1.12
High-dose oral vitamin C partially replenishes vitamin C levels in patients with Type 2 diabetes and low vitamin C levels but does not improve endothelial dysfunction or insulin resistance. Am J Physiol Heart Circ Physiol (2005) 1.11
Standard-dose vs high-dose multivitamin supplements for HIV. JAMA (2013) 1.08
Genetic variation in the sodium-dependent vitamin C transporters, SLC23A1, and SLC23A2 and risk for preterm delivery. Am J Epidemiol (2005) 1.08
Radiation therapy and tamoxifen: concurrent or sequential? That is the question. J Clin Oncol (2004) 1.06
Cloning and functional characterization of the mouse fructose transporter, GLUT5. Biochim Biophys Acta (2002) 1.05
Hemoglobin and plasma vitamin C levels in patients on peritoneal dialysis. Perit Dial Int (2010) 0.99
The role of mannosylated enzyme and the mannose receptor in enzyme replacement therapy. Am J Hum Genet (2005) 0.98
Parenteral ascorbate as a cancer therapeutic: a reassessment based on pharmacokinetics. Antioxid Redox Signal (2013) 0.97
Genetic variation in sodium-dependent vitamin C transporters SLC23A1 and SLC23A2 and risk of advanced colorectal adenoma. Nutr Cancer (2008) 0.96
The experience of conducting Mortality and Morbidity reviews in a pediatric interventional radiology service: a retrospective study. J Vasc Interv Radiol (2008) 0.93
Impaired adrenal catecholamine system function in mice with deficiency of the ascorbic acid transporter (SVCT2). FASEB J (2003) 0.92
Bystander responses to a violent incident in an immersive virtual environment. PLoS One (2013) 0.90
Vitamin and mineral supplements in the primary prevention of cardiovascular disease and cancer. Ann Intern Med (2014) 0.88
Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8. J Biol Chem (2013) 0.88
Fruit and vegetables: think variety, go ahead, eat! Am J Clin Nutr (2008) 0.87
Evidence-based approach to the introduction of positron emission tomography in ontario, Canada. J Clin Oncol (2009) 0.87
Vitamin C in mouse and human red blood cells: an HPLC assay. Anal Biochem (2012) 0.86
Short-term and long-term vitamin C supplementation in humans dose-dependently increases the resistance of plasma to ex vivo lipid peroxidation. Arch Biochem Biophys (2004) 0.86
Ascorbic acid kills Epstein-Barr virus positive Burkitt lymphoma cells and Epstein-Barr virus transformed B-cells in vitro, but not in vivo. Leuk Lymphoma (2012) 0.86
Comparative effectiveness research in oncology: an overview. J Clin Oncol (2012) 0.85
Risk of acute leukemia following epirubicin-based adjuvant chemotherapy: a report from the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol (2003) 0.85
Measurement of plasma volume using fluorescent silica-based nanoparticles. J Appl Physiol (1985) (2011) 0.83
Reduction of atherosclerotic plaques by lysosomal acid lipase supplementation. Arterioscler Thromb Vasc Biol (2003) 0.83
Prostate imaging modalities that can be used for complementary and alternative medicine clinical studies. Urol Clin North Am (2011) 0.83
Comment re: Vitamin C antagonizes the cytotoxic effects of chemotherapy. Cancer Res (2009) 0.82
Social meaning of ambiguous sounds influences retrospective duration judgments. Psychol Sci (2013) 0.81
Vitamin C: working on the x-axis. Am J Clin Nutr (2009) 0.81
Ocular surface squamous neoplasia in an anophthalmic socket 60 years after enucleation. Surv Ophthalmol (2011) 0.80
Helping to improve the group stereotype: on the strategic dimension of prosocial behavior. Pers Soc Psychol Bull (2007) 0.80
Enoxaparin in the treatment of deep vein thrombosis with or without pulmonary embolism: an individual patient data meta-analysis. Chest (2005) 0.79
Accuracy and safety of (99m)Tc-labeled anti-D-dimer (DI-80B3) Fab' fragments (ThromboView®) in the diagnosis of deep vein thrombosis: a phase II study. Thromb Res (2012) 0.79
More evidence that locoregional radiation therapy improves survival: what should we do? J Natl Cancer Inst (2005) 0.79
Imaging: PET-CT imaging in non-small-cell lung cancer. Nat Rev Clin Oncol (2009) 0.78
Epilogue: the peril and the promise of comparative effectiveness research in oncology. J Clin Oncol (2012) 0.78
The Initial Health Assessment: an intervention to identify the supportive care needs of cancer patients. Support Care Cancer (2003) 0.78
Antioxidant supplements and cardiovascular disease in men. JAMA (2009) 0.77
Economics of preoperative radiotherapy with total mesorectal excision: what can we learn from the Dutch experience? J Clin Oncol (2003) 0.77
Structures of a pan-specific antagonist antibody complexed to different isoforms of TGFβ reveal structural plasticity of antibody-antigen interactions. Protein Sci (2014) 0.77
Data collection in cancer clinical trials: Too much of a good thing? Clin Trials (2013) 0.76
Randomized, double-blind, placebo-controlled trial of epoetin alfa in men with castration-resistant prostate cancer and anemia. J Clin Oncol (2008) 0.76
Treatment of venous thromboembolism in cancer patients. Cancer Control (2005) 0.76
High-dose ascorbate with low-dose amphotericin B attenuates severity of disease in a model of the reappearance of candidemia during sepsis in the mouse. Am J Physiol Regul Integr Comp Physiol (2015) 0.76
Cloning, sequencing, and characterization of alternatively spliced glutaredoxin 1 cDNA and its genomic gene: chromosomal localization, mrna stability, and origin of pseudogenes. J Biol Chem (2005) 0.75
Single-lung ventilation in pediatrics. Can J Anaesth (2002) 0.75
The legacy of the 38 witnesses and the importance of getting history right. Am Psychol (2008) 0.75
Beyond prejudice: relational inequality, collective action, and social change revisited. Behav Brain Sci (2012) 0.75
Breast cancer consensus meetings: vive la difference? J Clin Oncol (2002) 0.75
Evisceration after complete evaluation an acceptable option. Arch Ophthalmol (2009) 0.75
Re: Is less more? Lessons in radiation schedules in breast cancer. J Natl Cancer Inst (2003) 0.75
Reply to C.M. Booth et al. J Clin Oncol (2013) 0.75
Radiotherapy for breast cancer. N Engl J Med (2002) 0.75