Published in CNS Drug Rev on January 01, 2006
Conotoxins targeting nicotinic acetylcholine receptors: an overview. Mar Drugs (2014) 1.09
The neuronal nicotinic alpha4beta2 receptor has a high maximal probability of being open. Br J Pharmacol (2010) 1.05
An autoradiographic survey of mouse brain nicotinic acetylcholine receptors defined by null mutants. Biochem Pharmacol (2011) 1.02
[11C]CHIBA-1001 as a novel PET ligand for alpha7 nicotinic receptors in the brain: a PET study in conscious monkeys. PLoS One (2008) 0.91
Auto/paracrine control of inflammatory cytokines by acetylcholine in macrophage-like U937 cells through nicotinic receptors. Int Immunopharmacol (2009) 0.89
Selective α4β2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons. Neuropsychopharmacology (2011) 0.86
Going up in smoke? A review of nAChRs-based treatment strategies for improving cognition in schizophrenia. Curr Pharm Des (2014) 0.86
Single photon emission computed tomography experience with (S)-5-[(123)I]iodo-3-(2-azetidinylmethoxy)pyridine in the living human brain of smokers and nonsmokers. Synapse (2009) 0.84
Brain imaging of nicotinic receptors in Alzheimer's disease. Int J Alzheimers Dis (2010) 0.82
Neurocircuitry of the nicotinic cholinergic system. Dialogues Clin Neurosci (2010) 0.80
Discovery of highly potent and selective α4β2-nicotinic acetylcholine receptor (nAChR) partial agonists containing an isoxazolylpyridine ether scaffold that demonstrate antidepressant-like activity. Part II. J Med Chem (2012) 0.80
Novel multifunctional pharmacology of lobinaline, the major alkaloid from Lobelia cardinalis. Fitoterapia (2016) 0.78
Galantamine-induced improvements in cognitive function are not related to alterations in alpha(4)beta (2) nicotinic receptors in early Alzheimer's disease as measured in vivo by 2-[18F]fluoro-A-85380 PET. Psychopharmacology (Berl) (2008) 0.77
Effects of nicotinic acetylcholine receptor agonists in assays of acute pain-stimulated and pain-depressed behaviors in rats. J Pharmacol Exp Ther (2015) 0.76
The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification. Cell (2002) 5.35
A single population of olfactory sensory neurons mediates an innate avoidance behaviour in Drosophila. Nature (2004) 4.52
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron (2007) 4.47
Genetic dissection of an amygdala microcircuit that gates conditioned fear. Nature (2010) 4.34
Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. Proc Natl Acad Sci U S A (2009) 3.98
Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus. Cell (2009) 3.97
Automated monitoring and analysis of social behavior in Drosophila. Nat Methods (2009) 3.94
Functional identification of an aggression locus in the mouse hypothalamus. Nature (2011) 3.88
Sensory nerves determine the pattern of arterial differentiation and blood vessel branching in the skin. Cell (2002) 3.84
Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms. J Clin Invest (2002) 3.70
Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd. Neuron (2005) 3.54
Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro. Neuron (2003) 3.27
Lhx6 delineates a pathway mediating innate reproductive behaviors from the amygdala to the hypothalamus. Neuron (2005) 3.21
Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags. Proc Natl Acad Sci U S A (2002) 3.15
Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease. J Neurochem (2005) 3.06
Allocrine modulation of feeding behavior by the Sex Peptide of Drosophila. Curr Biol (2006) 3.01
SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells. Neuron (2003) 2.98
TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms. Proc Natl Acad Sci U S A (2009) 2.96
Quantitative proteome analysis of human plasma following in vivo lipopolysaccharide administration using 16O/18O labeling and the accurate mass and time tag approach. Mol Cell Proteomics (2005) 2.50
Distinct sensory representations of wind and near-field sound in the Drosophila brain. Nature (2009) 2.32
An anatomic gene expression atlas of the adult mouse brain. Nat Neurosci (2009) 2.30
Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity. Genes Dev (2002) 2.19
Two different forms of arousal in Drosophila are oppositely regulated by the dopamine D1 receptor ortholog DopR via distinct neural circuits. Neuron (2009) 2.18
The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord. Neuron (2006) 2.18
Development and evaluation of a micro- and nanoscale proteomic sample preparation method. J Proteome Res (2005) 2.06
Development of NG2 neural progenitor cells requires Olig gene function. Proc Natl Acad Sci U S A (2006) 2.04
BCR-ABL1 compound mutations in tyrosine kinase inhibitor-resistant CML: frequency and clonal relationships. Blood (2012) 2.01
Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to Schwann cells. Development (2004) 1.98
Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes. Mol Pharmacol (2007) 1.98
Identification of an aggression-promoting pheromone and its receptor neurons in Drosophila. Nature (2009) 1.96
Reversible silencing of neuronal excitability in behaving mice by a genetically targeted, ivermectin-gated Cl- channel. Neuron (2007) 1.95
Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback. Development (2005) 1.93
Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Proc Natl Acad Sci U S A (2003) 1.90
Cardiovascular ephrinB2 function is essential for embryonic angiogenesis. Development (2002) 1.84
Light activation of an innate olfactory avoidance response in Drosophila. Curr Biol (2007) 1.81
Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code. Cell (2008) 1.79
Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch. Nat Neurosci (2007) 1.78
Wind, waves, and wing loading: morphological specialization may limit range expansion of endangered albatrosses. PLoS One (2008) 1.74
Hierarchical chemosensory regulation of male-male social interactions in Drosophila. Nat Neurosci (2011) 1.72
Selective electrical silencing of mammalian neurons in vitro by the use of invertebrate ligand-gated chloride channels. J Neurosci (2002) 1.71
A common genetic target for environmental and heritable influences on aggressiveness in Drosophila. Proc Natl Acad Sci U S A (2008) 1.68
Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway. Proc Natl Acad Sci U S A (2002) 1.67
Visualizing neuromodulation in vivo: TANGO-mapping of dopamine signaling reveals appetite control of sugar sensing. Cell (2012) 1.65
In vitro electrical properties for iridium oxide versus titanium nitride stimulating electrodes. IEEE Trans Biomed Eng (2002) 1.63
Trace but not delay fear conditioning requires attention and the anterior cingulate cortex. Proc Natl Acad Sci U S A (2003) 1.60
Management of unstable/acute slipped capital femoral epiphysis: results of a survey of the POSNA membership. J Pediatr Orthop (2005) 1.57
The ABL switch control inhibitor DCC-2036 is active against the chronic myeloid leukemia mutant BCR-ABLT315I and exhibits a narrow resistance profile. Cancer Res (2011) 1.53
An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo. J Pharmacol Exp Ther (2007) 1.53
Mrgprd enhances excitability in specific populations of cutaneous murine polymodal nociceptors. J Neurosci (2009) 1.53
The origin and diversification of Galapagos mockingbirds. Evolution (2006) 1.50
Identification of the subthalamic nucleus in deep brain stimulation surgery with a novel wavelet-derived measure of neural background activity. J Neurosurg (2009) 1.49
A Cre-dependent, anterograde transsynaptic viral tracer for mapping output pathways of genetically marked neurons. Neuron (2011) 1.49
Spatial mapping of protein abundances in the mouse brain by voxelation integrated with high-throughput liquid chromatography-mass spectrometry. Genome Res (2007) 1.46
Using a common average reference to improve cortical neuron recordings from microelectrode arrays. J Neurophysiol (2008) 1.45
Comparison of the generic neuronal differentiation and neuron subtype specification functions of mammalian achaete-scute and atonal homologs in cultured neural progenitor cells. Development (2002) 1.44
Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo. Nature (2013) 1.43
Structure-activity relationship studies on a series of novel, substituted 1-benzyl-5-phenyltetrazole P2X7 antagonists. J Med Chem (2006) 1.36
Allatostatin-A neurons inhibit feeding behavior in adult Drosophila. Proc Natl Acad Sci U S A (2012) 1.34
Transient expression of the bHLH factor neurogenin-2 marks a subpopulation of neural crest cells biased for a sensory but not a neuronal fate. Proc Natl Acad Sci U S A (2002) 1.33
Improved proteome coverage by using high efficiency cysteinyl peptide enrichment: the human mammary epithelial cell proteome. Proteomics (2005) 1.33
Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways. J Neurosci (2007) 1.32
Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo. Proc Natl Acad Sci U S A (2006) 1.30
A-366833: a novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]-heptane alpha4beta2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models. Biochem Pharmacol (2007) 1.27
Neural correlates of competing fear behaviors evoked by an innately aversive stimulus. J Neurosci (2003) 1.25
Localization of histamine H4 receptors in the central nervous system of human and rat. Brain Res (2008) 1.24
Multidimensional proteome analysis of human mammary epithelial cells. J Proteome Res (2004) 1.24
Pain behavior in the formalin test persists after ablation of the great majority of C-fiber nociceptors. Pain (2010) 1.22
Waved albatrosses can navigate with strong magnets attached to their head. J Exp Biol (2003) 1.20
Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network. Proc Natl Acad Sci U S A (2008) 1.20
Mas-related G-protein-coupled receptors inhibit pathological pain in mice. Proc Natl Acad Sci U S A (2010) 1.20
Allosteric modulators of the alpha7 nicotinic acetylcholine receptor. J Med Chem (2008) 1.14
Mechanisms of compartmentalized expression of Mrg class G-protein-coupled sensory receptors. J Neurosci (2008) 1.14
Auditory cortical responses to electrical stimulation of the inferior colliculus: implications for an auditory midbrain implant. J Neurophysiol (2006) 1.12
Syntheses and structure-activity relationship (SAR) studies of 2,5-diazabicyclo[2.2.1]heptanes as novel alpha7 neuronal nicotinic receptor (NNR) ligands. Bioorg Med Chem Lett (2010) 1.10
Conducting polymers on hydrogel-coated neural electrode provide sensitive neural recordings in auditory cortex. Acta Biomater (2009) 1.08
Novel multi-sided, microelectrode arrays for implantable neural applications. Biomed Microdevices (2011) 1.05
Decoding ventromedial hypothalamic neural activity during male mouse aggression. J Neurosci (2014) 1.04
Antidromic activation reveals tonotopically organized projections from primary auditory cortex to the central nucleus of the inferior colliculus in guinea pig. J Neurophysiol (2006) 1.04
Developmental changes in Notch1 and numb expression mediated by local cell-cell interactions underlie progressively increasing delta sensitivity in neural crest stem cells. Dev Biol (2002) 1.03
Role of channel activation in cognitive enhancement mediated by alpha7 nicotinic acetylcholine receptors. Br J Pharmacol (2009) 1.02
A neuropeptide circuit that coordinates sperm transfer and copulation duration in Drosophila. Proc Natl Acad Sci U S A (2012) 1.01
Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM. J Neurophysiol (2003) 0.99
Stimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity alpha4beta2 subunit combination. Biochem Pharmacol (2009) 0.99
In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease. J Pharmacol Exp Ther (2010) 0.98
2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases. Bioorg Med Chem Lett (2007) 0.97
Spatially distinct functional output regions within the central nucleus of the inferior colliculus: implications for an auditory midbrain implant. J Neurosci (2007) 0.97
Prokineticin 2 is a target gene of proneural basic helix-loop-helix factors for olfactory bulb neurogenesis. J Biol Chem (2007) 0.97
Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties. CNS Neurosci Ther (2008) 0.96
Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats. Proc Natl Acad Sci U S A (2004) 0.96
Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord. Mol Pain (2011) 0.95
Discovery of novel glucose-regulated proteins in isolated human pancreatic islets using LC-MS/MS-based proteomics. J Proteome Res (2012) 0.94
Antisense knockdown of the rat alpha7 nicotinic acetylcholine receptor produces spatial memory impairment. Neurosci Lett (2006) 0.94
Involvement of DRG11 in the development of the primary afferent nociceptive system. Mol Cell Neurosci (2006) 0.94