Published in J Biol Chem on November 05, 1990
Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol Cell Biol (1999) 5.55
Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest. J Biol Chem (1996) 5.52
Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability. Mol Cell Biol (2001) 3.12
Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase pathways. Mol Cell Biol (2006) 2.21
The TIS11 primary response gene is a member of a gene family that encodes proteins with a highly conserved sequence containing an unusual Cys-His repeat. Mol Cell Biol (1991) 2.06
The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis. Arthritis Res Ther (2004) 2.05
The zinc finger antiviral protein directly binds to specific viral mRNAs through the CCCH zinc finger motifs. J Virol (2004) 2.02
Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action. Biochim Biophys Acta (2013) 1.90
Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-alpha and phorbol ester. J Clin Invest (1994) 1.89
Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/macrophage progenitors may be responsible for TNFalpha overproduction. J Clin Invest (1997) 1.78
Immunological characterization of tristetraprolin as a low abundance, inducible, stable cytosolic protein. J Biol Chem (2004) 1.65
Identification of RNA-protein interaction networks using PAR-CLIP. Wiley Interdiscip Rev RNA (2011) 1.61
Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice. BMC Genomics (2008) 1.55
The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes. Oncogene (2010) 1.43
Metal binding properties and secondary structure of the zinc-binding domain of Nup475. Proc Natl Acad Sci U S A (1996) 1.40
Transcriptional repression by the Caenorhabditis elegans germ-line protein PIE-1. Genes Dev (1999) 1.39
Cleavage of RNA hairpins mediated by a developmentally regulated CCCH zinc finger protein. Mol Cell Biol (1996) 1.38
The human TTP protein: sequence, alignment with related proteins, and chromosomal localization of the mouse and human genes. Nucleic Acids Res (1991) 1.35
The role of tristetraprolin in cancer and inflammation. Front Biosci (Landmark Ed) (2012) 1.33
Ebola virus transcription activator VP30 is a zinc-binding protein. J Virol (2003) 1.29
Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis. Biochem J (2006) 1.26
Myeloid-specific tristetraprolin deficiency in mice results in extreme lipopolysaccharide sensitivity in an otherwise minimal phenotype. J Immunol (2012) 1.24
The roles of TTP and BRF proteins in regulated mRNA decay. Wiley Interdiscip Rev RNA (2011) 1.24
TIS11 family proteins and their roles in posttranscriptional gene regulation. J Biomed Biotechnol (2009) 1.21
The respiratory syncytial virus M2-1 protein forms tetramers and interacts with RNA and P in a competitive manner. J Virol (2009) 1.20
Glucocorticoids regulate tristetraprolin synthesis and posttranscriptionally regulate tumor necrosis factor alpha inflammatory signaling. Mol Cell Biol (2006) 1.18
Tristetraprolin impairs NF-kappaB/p65 nuclear translocation. J Biol Chem (2009) 1.17
Expression and purification of recombinant tristetraprolin that can bind to tumor necrosis factor-alpha mRNA and serve as a substrate for mitogen-activated protein kinases. Arch Biochem Biophys (2003) 1.16
C. elegans GLA-3 is a novel component of the MAP kinase MPK-1 signaling pathway required for germ cell survival. Genes Dev (2006) 1.15
Expression, purification, and biochemical characterization of the antiinflammatory tristetraprolin: a zinc-dependent mRNA binding protein affected by posttranslational modifications. Biochemistry (2004) 1.12
Phosphorylation site analysis of the anti-inflammatory and mRNA-destabilizing protein tristetraprolin. Expert Rev Proteomics (2007) 1.06
The embryonically active gene, unkempt, of Drosophila encodes a Cys3His finger protein. Genetics (1992) 1.04
Down-regulation of tristetraprolin expression results in enhanced IL-12 and MIP-2 production and reduced MIP-3alpha synthesis in activated macrophages. Mediators Inflamm (2006) 1.03
Genetic selection of growth-inhibitory sequences in mammalian cells. Proc Natl Acad Sci U S A (1994) 1.01
A unique C-terminal repeat domain maintains the cytosolic localization of the placenta-specific tristetraprolin family member ZFP36L3. J Biol Chem (2008) 0.99
Green tea increases anti-inflammatory tristetraprolin and decreases pro-inflammatory tumor necrosis factor mRNA levels in rats. J Inflamm (Lond) (2007) 0.99
Schizosaccharomyces pombe zfs1+ encoding a zinc-finger protein functions in the mating pheromone recognition pathway. Mol Biol Cell (1995) 0.99
Inflammation: cytokines and RNA-based regulation. Wiley Interdiscip Rev RNA (2010) 0.92
Deletion of tristetraprolin caused spontaneous reactive granulopoiesis by a non-cell-autonomous mechanism without disturbing long-term hematopoietic stem cell quiescence. J Immunol (2011) 0.88
RNase-L control of cellular mRNAs: roles in biologic functions and mechanisms of substrate targeting. J Interferon Cytokine Res (2014) 0.88
Regulation and localization of endogenous human tristetraprolin. Arthritis Res Ther (2003) 0.88
Phosphorylation of recombinant tristetraprolin in vitro. Protein J (2008) 0.87
Inhibition of tristetraprolin deadenylation by poly(A) binding protein. Am J Physiol Gastrointest Liver Physiol (2008) 0.87
Transforming growth factor β regulates P-body formation through induction of the mRNA decay factor tristetraprolin. Mol Cell Biol (2013) 0.86
Mutational and structural analysis of the tandem zinc finger domain of tristetraprolin. J Biol Chem (2013) 0.86
The Arabidopsis thaliana tandem zinc finger 1 (AtTZF1) protein in RNA binding and decay. Plant J (2014) 0.86
Analyses of SELEX-derived ZAP-binding RNA aptamers suggest that the binding specificity is determined by both structure and sequence of the RNA. Protein Cell (2010) 0.84
Quantitative evaluation of His-tag purification and immunoprecipitation of tristetraprolin and its mutant proteins from transfected human cells. Biotechnol Prog (2009) 0.82
Coordinated expression of tristetraprolin post-transcriptionally attenuates mitogenic induction of the oncogenic Ser/Thr kinase Pim-1. PLoS One (2012) 0.82
Characterization of genomic vitamin D receptor binding sites through chromatin looping and opening. PLoS One (2014) 0.81
Tristetraprolin represses estrogen receptor α transactivation in breast cancer cells. J Biol Chem (2014) 0.80
Tristetraprolin inhibits poly(A)-tail synthesis in nuclear mRNA that contains AU-rich elements by interacting with poly(A)-binding protein nuclear 1. PLoS One (2012) 0.80
Tristetraprolin suppresses the EMT through the down-regulation of Twist1 and Snail1 in cancer cells. Oncotarget (2016) 0.80
Identification of a functional promoter element in the 5'-flanking region of the rat cMG1/TIS11b gene. Biochem J (1995) 0.79
Comparative functional analysis of ZFP36 genes during Xenopus development. PLoS One (2013) 0.79
Growth hormone potentiates 17β-estradiol-dependent breast cancer cell proliferation independently of IGF-I receptor signaling. Endocrinology (2013) 0.79
RNase L attenuates mitogen-stimulated gene expression via transcriptional and post-transcriptional mechanisms to limit the proliferative response. J Biol Chem (2014) 0.79
Myeloid ZFP36L1 does not regulate inflammation or host defense in mouse models of acute bacterial infection. PLoS One (2014) 0.79
Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-κB-dependent transcription of TNF-α and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA. J Inflamm (Lond) (2010) 0.78
Polyubiquitinated tristetraprolin protects from TNF-induced, caspase-mediated apoptosis. J Biol Chem (2014) 0.78
Increases in nup475 and c-jun are early molecular events that precede the adaptive hyperplastic response after small bowel resection. Ann Surg (1995) 0.78
Three Residues Make an Evolutionary Switch for Folding and RNA-Destabilizing Activity in the TTP Family of Proteins. ACS Chem Biol (2015) 0.78
RNA binding proteins as regulators of immune cell biology. Clin Exp Immunol (2015) 0.77
LARP4 Is Regulated by Tumor Necrosis Factor Alpha in a Tristetraprolin-Dependent Manner. Mol Cell Biol (2015) 0.75
The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases. Biochem Soc Trans (2016) 0.75
Inactivation of tristetraprolin in chronic hypoxia provokes the expression of cathepsin B. Mol Cell Biol (2014) 0.75
An Ancient Family of RNA-Binding Proteins: Still Important! Trends Biochem Sci (2017) 0.75
Nuclear tristetraprolin acts as a corepressor of multiple steroid nuclear receptors in breast cancer cells. Mol Genet Metab Rep (2016) 0.75
Tristetraprolin as a Therapeutic Target in Inflammatory Disease. Trends Pharmacol Sci (2016) 0.75
Restriction endonucleases in the analysis and restructuring of dna molecules. Annu Rev Biochem (1975) 11.76
Specific cleavage of simian virus 40 DNA by restriction endonuclease of Hemophilus influenzae. Proc Natl Acad Sci U S A (1971) 10.06
Studies of simian virus 40 DNA. VII. A cleavage map of the SV40 genome. J Mol Biol (1973) 9.30
Letter: A suggested nomenclature for bacterial host modification and restriction systems and their enzymes. J Mol Biol (1973) 9.17
Local mutagenesis: a method for generating viral mutants with base substitutions in preselected regions of the viral genome. Proc Natl Acad Sci U S A (1978) 8.36
A gene activated by growth factors is related to the oncogene v-jun. Proc Natl Acad Sci U S A (1988) 7.47
Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc. Proc Natl Acad Sci U S A (1987) 7.38
Isolation of mutants of an animal virus in bacteria. Science (1980) 6.81
Bidirectional replication of Simian Virus 40 DNA. Proc Natl Acad Sci U S A (1972) 6.79
Budding yeast Cdc20: a target of the spindle checkpoint. Science (1998) 6.59
MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell (1993) 6.55
Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells. EMBO J (1985) 6.31
DNA binding activities of three murine Jun proteins: stimulation by Fos. Cell (1988) 6.13
Deletion mutants of simian virus 40 generated by enzymatic excision of DNA segments from the viral genome. J Mol Biol (1974) 5.47
Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun. Proc Natl Acad Sci U S A (1992) 5.28
Directed mutagenesis. Annu Rev Genet (1981) 5.27
A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences. Proc Natl Acad Sci U S A (1988) 5.25
A map of simian virus 40 transcription sites expressed in productively infected cells. J Mol Biol (1973) 5.02
Identification of simian virus 40 protein A. J Virol (1977) 4.93
Posttranscriptional selection of simian virus 40-specific RNA. J Virol (1975) 4.87
A map of temperature-sensitive mutants of simian virus 40. Virology (1975) 4.77
DNA binding site of the growth factor-inducible protein Zif268. Proc Natl Acad Sci U S A (1989) 4.52
Specific origin in SV40 DNA replication. Nat New Biol (1972) 4.39
The isolation of simian virus 40 variants with specifically altered genomes. Proc Natl Acad Sci U S A (1974) 4.35
Mapping temperature-sensitive mutants of simian virus 40: rescue of mutants by fragments of viral DNA. Virology (1974) 4.30
Mutational analysis of the simian virus 40 replicon: pseudorevertants of mutants with a defective replication origin. Proc Natl Acad Sci U S A (1979) 4.15
BRCA1 dysfunction in sporadic basal-like breast cancer. Oncogene (2006) 3.91
A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily. Proc Natl Acad Sci U S A (1988) 3.77
Cold-sensitive regulatory mutants of simian virus 40. J Mol Biol (1980) 3.77
Regulatory mutants of simian virus 40: constructed mutants with base substitutions at the origin of DNA replication. J Mol Biol (1979) 3.75
Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol Cell Biol (1991) 3.70
Mutational analysis of simian virus 40 T antigen: isolation and characterization of mutants with deletions in the T-antigen gene. Mol Cell Biol (1983) 3.67
jun-D: a third member of the jun gene family. Proc Natl Acad Sci U S A (1989) 3.47
Letter: Potential biohazards of recombinant DNA molecules. Science (1974) 3.45
The genome of simian virus 40. Adv Virus Res (1977) 3.42
Growth-related changes in specific mRNAs of cultured mouse cells. Proc Natl Acad Sci U S A (1983) 3.35
Regulatory mutants of simian virus 40. Effect of mutations at a T antigen binding site on DNA replication and expression of viral genes. J Mol Biol (1982) 3.22
CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth. Proc Natl Acad Sci U S A (1998) 3.18
A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity. Cell (1991) 3.12
Evidence of p53-dependent cross-talk between ribosome biogenesis and the cell cycle: effects of nucleolar protein Bop1 on G(1)/S transition. Mol Cell Biol (2001) 3.10
Biochemical activities of T-antigen proteins encoded by simian virus 40 A gene deletion mutants. Mol Cell Biol (1983) 3.06
Growth factor-induced delayed early response genes. Mol Cell Biol (1992) 3.03
Induction of protooncogene c-jun by serum growth factors. Proc Natl Acad Sci U S A (1988) 2.92
An altered DNA conformation in origin region I is a determinant for the binding of SV40 large T antigen. Cell (1986) 2.88
Topography of simian virus 40 A protein-DNA complexes: arrangement of protein bound to the origin of replication. J Virol (1983) 2.79
Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo. Mol Cell Biol (1999) 2.67
Isolation of cloned cDNA encoding mammalian ornithine decarboxylase. Proc Natl Acad Sci U S A (1984) 2.64
Expression of cyr61, a growth factor-inducible immediate-early gene. Mol Cell Biol (1990) 2.64
SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family. Neuron (1998) 2.63
Nucleotide sequence of murine ornithine decarboxylase mRNA. Proc Natl Acad Sci U S A (1985) 2.57
The evolution of new species of viral DNA during serial passage of simian virus 40 at high multiplicity. Virology (1973) 2.53
An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene. Proc Natl Acad Sci U S A (1991) 2.44
Cyr61, a product of a growth factor-inducible immediate-early gene, promotes cell proliferation, migration, and adhesion. Mol Cell Biol (1996) 2.44
Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3. Proc Natl Acad Sci U S A (1995) 2.42
Evolutionary variants of simian virus 40: Nucleotide sequence of a conserved SV40 DNA segment containing the origin of viral DNA replication as an inverted repetition. J Mol Biol (1978) 2.32
Phage lambda gene Q antiterminator recognizes RNA polymerase near the promoter and accelerates it through a pause site. Cell (1985) 2.31
The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts. J Biol Chem (2000) 2.28
rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein. J Biol Chem (1994) 2.25
Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction. Genes Dev (1989) 2.17
cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein. Oncogene (1992) 2.17
Synthetic adaptors for cloning DNA. Methods Enzymol (1979) 2.14
The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts. J Biol Chem (2001) 2.13
SAP102, a novel postsynaptic protein that interacts with NMDA receptor complexes in vivo. Neuron (1996) 2.10
Purification of simian virus 40 large T antigen by immunoaffinity chromatography. J Virol (1985) 2.01
Bop1 is a mouse WD40 repeat nucleolar protein involved in 28S and 5. 8S RRNA processing and 60S ribosome biogenesis. Mol Cell Biol (2000) 2.00
Proposal for a unified CCN nomenclature. Mol Pathol (2003) 1.98
Evolutionary variants of simian virus 40: Cellular DNA sequences and sequences at recombinant joints of substituted variants. J Mol Biol (1978) 1.96
A colinear map relating the simian virus 40 (SV40) DNA segments of six adenovirus-SV40 hybrids to the DNA fragments produced by restriction endonuclease cleavage of SV40 DNA. Proc Natl Acad Sci U S A (1974) 1.94
Cell-free protein synthesis directed by coliphage MS2 RNA: synthesis of intact viral coat protein and other products. J Mol Biol (1965) 1.89
Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development. Exp Cell Res (1997) 1.88
Convulsant-induced increase in transcription factor messenger RNAs in rat brain. Proc Natl Acad Sci U S A (1988) 1.88
Nucleotide sequence of a growth-related mRNA encoding a member of the prolactin-growth hormone family. Proc Natl Acad Sci U S A (1984) 1.82
Studies of SV40 DNA. VI. Cleavage of SV40 DNA by restriction endonuclease from Hemophilus parainfluenzae. Virology (1973) 1.81
Local mutagenesis within deletion loops of DNA heteroduplexes. Proc Natl Acad Sci U S A (1982) 1.81
The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase. Proc Natl Acad Sci U S A (1993) 1.81
Studies of SV40 DNA. 3. Differences in DNA from various strains of SV40. J Mol Biol (1972) 1.79
Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin alphavbeta3. J Biol Chem (1998) 1.78
Functional serum response elements upstream of the growth factor-inducible gene zif268. Mol Cell Biol (1989) 1.78
The basic region of Fos mediates specific DNA binding. EMBO J (1989) 1.75
The nucleic acid of an SV40-like virus isolated from a patient with progressive multifocal leukoencephalopathy. Virology (1973) 1.71
RNA polymerase pausing and transcript release at the lambda tR1 terminator in vitro. J Biol Chem (1983) 1.71
The B/C gene of simian virus 40. Virology (1976) 1.67
Mapping the genes of simian virus 40. Cold Spring Harb Symp Quant Biol (1975) 1.66
Simian virus 40 mutant T antigens with relaxed specificity for the nucleotide sequence at the viral DNA origin of replication. J Virol (1984) 1.65
Seventeen base pairs of region I encode a novel tripartite binding signal for SV40 T antigen. Cell (1985) 1.64
Mutants of simian virus 40 with base substitutions at the origin of DNA replication. Cold Spring Harb Symp Quant Biol (1979) 1.58
In vitro activation of Stat3 by epidermal growth factor receptor kinase. Proc Natl Acad Sci U S A (1996) 1.58
Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycans. J Biol Chem (2000) 1.58
Cyr61, product of a growth factor-inducible immediate early gene, is associated with the extracellular matrix and the cell surface. Cell Growth Differ (1991) 1.55
Molecular mechanisms of glutamate receptor clustering at excitatory synapses. Curr Opin Neurobiol (1998) 1.52
Multivalent DNA-binding properties of the HMG-1 proteins. Proc Natl Acad Sci U S A (1996) 1.51
Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3). J Biol Chem (1999) 1.50
A transcriptional map of the SV40 genome in transformed cell lines. Virology (1975) 1.49