Published in Biophys J on September 29, 2006
Sensing voltage across lipid membranes. Nature (2008) 2.66
Structure and hydration of membranes embedded with voltage-sensing domains. Nature (2009) 2.15
Dynamics of the Kv1.2 voltage-gated K+ channel in a membrane environment. Biophys J (2007) 2.10
Calculation of the gating charge for the Kv1.2 voltage-activated potassium channel. Biophys J (2010) 1.87
The membrane potential and its representation by a constant electric field in computer simulations. Biophys J (2008) 1.68
Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer. Structure (2008) 1.64
Conformational changes and slow dynamics through microsecond polarized atomistic molecular simulation of an integral Kv1.2 ion channel. PLoS Comput Biol (2009) 1.51
How does a voltage sensor interact with a lipid bilayer? Simulations of a potassium channel domain. Structure (2007) 1.46
An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1. Nat Struct Mol Biol (2010) 1.44
Membrane protein insertion: the biology-physics nexus. J Gen Physiol (2007) 1.42
In search of a consensus model of the resting state of a voltage-sensing domain. Neuron (2011) 1.36
Spontaneous membrane-translocating peptides by orthogonal high-throughput screening. J Am Chem Soc (2011) 1.35
Voltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) family. Physiol Rev (2013) 1.35
Gating pore currents in DIIS4 mutations of NaV1.4 associated with periodic paralysis: saturation of ion flux and implications for disease pathogenesis. J Gen Physiol (2008) 1.35
The activated state of a sodium channel voltage sensor in a membrane environment. Proc Natl Acad Sci U S A (2010) 1.18
Construction and validation of a homology model of the human voltage-gated proton channel hHV1. J Gen Physiol (2013) 1.17
Molecular dynamics simulation of Kv channel voltage sensor helix in a lipid membrane with applied electric field. Biophys J (2008) 1.13
3₁₀-helix conformation facilitates the transition of a voltage sensor S4 segment toward the down state. Biophys J (2011) 1.11
Water wires in atomistic models of the Hv1 proton channel. Biochim Biophys Acta (2011) 1.07
Voltage-gated proton channels. Cell Mol Life Sci (2008) 1.06
Down-state model of the voltage-sensing domain of a potassium channel. Biophys J (2010) 1.06
Gating pore currents and the resting state of Nav1.4 voltage sensor domains. Proc Natl Acad Sci U S A (2012) 1.06
Transfer of arginine into lipid bilayers is nonadditive. Biophys J (2011) 1.05
A look at arginine in membranes. J Membr Biol (2010) 1.05
Bubbles, gating, and anesthetics in ion channels. Biophys J (2008) 1.02
Modeling and simulation of ion channels. Chem Rev (2012) 1.02
Evolutionary imprint of activation: the design principles of VSDs. J Gen Physiol (2014) 1.02
Determinants of water permeability through nanoscopic hydrophilic channels. Biophys J (2009) 1.01
Structural refinement of the hERG1 pore and voltage-sensing domains with ROSETTA-membrane and molecular dynamics simulations. Proteins (2010) 0.92
The influence of lipids on voltage-gated ion channels. Curr Opin Struct Biol (2012) 0.90
Electron spin-echo envelope modulation (ESEEM) reveals water and phosphate interactions with the KcsA potassium channel. Biochemistry (2010) 0.90
Profile structures of the voltage-sensor domain and the voltage-gated K(+)-channel vectorially oriented in a single phospholipid bilayer membrane at the solid-vapor and solid-liquid interfaces determined by x-ray interferometry. Phys Rev E Stat Nonlin Soft Matter Phys (2011) 0.90
Mechanism Matters: A Taxonomy of Cell Penetrating Peptides. Trends Biochem Sci (2015) 0.89
Molecular dynamics simulations of voltage-gated cation channels: insights on voltage-sensor domain function and modulation. Front Pharmacol (2012) 0.87
A highly charged voltage-sensor helix spontaneously translocates across membranes. Angew Chem Int Ed Engl (2012) 0.87
Microscopic origin of gating current fluctuations in a potassium channel voltage sensor. Biophys J (2012) 0.86
Structural interactions between lipids, water and S1-S4 voltage-sensing domains. J Mol Biol (2012) 0.86
Membrane insertion of a voltage sensor helix. Biophys J (2011) 0.84
Quantum mechanical calculations of charge effects on gating the KcsA channel. Biochim Biophys Acta (2007) 0.81
Potassium channel opening: a subtle two-step. J Physiol (2009) 0.81
The last few frames of the voltage-gating movie. Biophys J (2007) 0.80
Voltage Sensing in Membranes: From Macroscopic Currents to Molecular Motions. J Membr Biol (2015) 0.80
Structural dynamics of the S4 voltage-sensor helix in lipid bilayers lacking phosphate groups. J Phys Chem B (2011) 0.79
Voltage-dependent conformational changes of KVAP S4 segment in bacterial membrane environment. Channels (Austin) (2009) 0.79
Electric fingerprint of voltage sensor domains. Proc Natl Acad Sci U S A (2014) 0.78
Implicit membrane treatment of buried charged groups: application to peptide translocation across lipid bilayers. Biochim Biophys Acta (2014) 0.78
Mechanisms of activation of voltage-gated potassium channels. Acta Naturae (2014) 0.77
The Hv1 proton channel responds to mechanical stimuli. J Gen Physiol (2016) 0.76
Proton currents constrain structural models of voltage sensor activation. Elife (2016) 0.75
X-ray structure of a voltage-dependent K+ channel. Nature (2003) 14.50
Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel. Neuron (1996) 8.20
Contribution of the S4 segment to gating charge in the Shaker K+ channel. Neuron (1996) 8.11
Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor. Nature (2005) 6.85
A proton pore in a potassium channel voltage sensor reveals a focused electric field. Nature (2004) 5.66
A voltage sensor-domain protein is a voltage-gated proton channel. Science (2006) 5.07
A voltage-gated proton-selective channel lacking the pore domain. Nature (2006) 4.89
Structure of the KvAP voltage-dependent K+ channel and its dependence on the lipid membrane. Proc Natl Acad Sci U S A (2005) 3.25
Voltage-sensing arginines in a potassium channel permeate and occlude cation-selective pores. Neuron (2005) 2.94
Ion permeation through a voltage- sensitive gating pore in brain sodium channels having voltage sensor mutations. Neuron (2005) 1.95
Environment of the gating charges in the Kv1.2 Shaker potassium channel. Biophys J (2006) 1.89
The intrinsic flexibility of the Kv voltage sensor and its implications for channel gating. Biophys J (2005) 1.07
Update of the CHARMM all-atom additive force field for lipids: validation on six lipid types. J Phys Chem B (2010) 8.70
Recognition of transmembrane helices by the endoplasmic reticulum translocon. Nature (2005) 7.72
A comprehensive classification system for lipids. J Lipid Res (2005) 6.52
Molecular code for transmembrane-helix recognition by the Sec61 translocon. Nature (2007) 4.60
Membrane insertion of a potassium-channel voltage sensor. Science (2005) 3.30
Interface connections of a transmembrane voltage sensor. Proc Natl Acad Sci U S A (2005) 2.92
Specific ion effects at the air/water interface. Chem Rev (2006) 2.25
Structure and hydration of membranes embedded with voltage-sensing domains. Nature (2009) 2.15
Experimental validation of molecular dynamics simulations of lipid bilayers: a new approach. Biophys J (2004) 2.09
MPEx: a tool for exploring membrane proteins. Protein Sci (2009) 1.89
AND/R: Advanced neutron diffractometer/reflectometer for investigation of thin films and multilayers for the life sciences. Rev Sci Instrum (2006) 1.86
Arginine in membranes: the connection between molecular dynamics simulations and translocon-mediated insertion experiments. J Membr Biol (2010) 1.58
Folding amphipathic helices into membranes: amphiphilicity trumps hydrophobicity. J Mol Biol (2007) 1.52
Rhomboid protease dynamics and lipid interactions. Structure (2009) 1.40
Predicting in vivo clinical performance of anterior cruciate ligament fixation methods from in vitro analysis: industrial tests of fatigue life and tolerance limits are more useful than other cyclic loading parameters. Am J Sports Med (2005) 1.38
Interfacial folding and membrane insertion of a designed helical peptide. Biochemistry (2004) 1.38
Asn- and Asp-mediated interactions between transmembrane helices during translocon-mediated membrane protein assembly. EMBO Rep (2006) 1.33
Insertion of short transmembrane helices by the Sec61 translocon. Proc Natl Acad Sci U S A (2009) 1.31
Unified molecular picture of the surfaces of aqueous acid, base, and salt solutions. J Phys Chem B (2005) 1.30
Coincidence of dynamical transitions in a soluble protein and its hydration water: direct measurements by neutron scattering and MD simulations. J Am Chem Soc (2008) 1.27
Molecular code for protein insertion in the endoplasmic reticulum membrane is similar for N(in)-C(out) and N(out)-C(in) transmembrane helices. Proc Natl Acad Sci U S A (2008) 1.21
In silico partitioning and transmembrane insertion of hydrophobic peptides under equilibrium conditions. J Am Chem Soc (2011) 1.20
Reversible refolding of the diphtheria toxin T-domain on lipid membranes. Biochemistry (2004) 1.17
Self-induced docking site of a deeply embedded peripheral membrane protein. Biophys J (2006) 1.14
Investigation of finite system-size effects in molecular dynamics simulations of lipid bilayers. J Phys Chem B (2006) 1.12
An experiment-based algorithm for predicting the partitioning of unfolded peptides into phosphatidylcholine bilayer interfaces. Biochemistry (2005) 1.11
Hydration of POPC bilayers studied by 1H-PFG-MAS-NOESY and neutron diffraction. Eur Biophys J (2007) 1.10
Determining the membrane topology of proteins: insertion pathway of a transmembrane helix of annexin 12. Biochemistry (2002) 1.09
Water wires in atomistic models of the Hv1 proton channel. Biochim Biophys Acta (2011) 1.07
Air-liquid interfaces of aqueous solutions containing ammonium and sulfate: spectroscopic and molecular dynamics studies. J Phys Chem B (2005) 1.06
Down-state model of the voltage-sensing domain of a potassium channel. Biophys J (2010) 1.06
Structure and dynamics of the aqueous liquid-vapor interface: a comprehensive particle-based simulation study. J Phys Chem B (2006) 1.04
CD spectroscopy of peptides and proteins bound to large unilamellar vesicles. J Membr Biol (2010) 1.04
Dynamics of SecY translocons with translocation-defective mutations. Structure (2010) 1.02
Separating instability from aggregation propensity in γS-crystallin variants. Biophys J (2011) 1.01
Aggregation behavior of an ultra-pure lipopolysaccharide that stimulates TLR-4 receptors. Biophys J (2008) 1.01
Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum. Proc Natl Acad Sci U S A (2011) 0.99
Outer membrane phospholipase A in phospholipid bilayers: a model system for concerted computational and experimental investigations of amino acid side chain partitioning into lipid bilayers. Biochim Biophys Acta (2011) 0.98
Allosteric mechanism of water-channel gating by Ca2+-calmodulin. Nat Struct Mol Biol (2013) 0.98
Spectral signatures of the pentagonal water cluster in bacteriorhodopsin. Chemphyschem (2008) 0.96
Hydrogen-bond energetics drive helix formation in membrane interfaces. Biochim Biophys Acta (2011) 0.95
Molecular dynamics simulations of atmospheric oxidants at the air-water interface: solvation and accommodation of OH and O3. J Phys Chem B (2005) 0.94
Structure and vibrational spectroscopy of salt water/air interfaces: predictions from classical molecular dynamics simulations. J Phys Chem B (2005) 0.94
Acyl-chain methyl distributions of liquid-ordered and -disordered membranes. Biophys J (2011) 0.94
pH dependence of sphingosine aggregation. Biophys J (2009) 0.93
Membrane partitioning: "classical" and "nonclassical" hydrophobic effects. J Membr Biol (2010) 0.91
Structure and dynamics of cholesterol-containing polyunsaturated lipid membranes studied by neutron diffraction and NMR. J Membr Biol (2010) 0.90
Watching the low-frequency motions in aqueous salt solutions: the terahertz vibrational signatures of hydrated ions. J Am Chem Soc (2011) 0.90
Diffraction-based density restraints for membrane and membrane-peptide molecular dynamics simulations. Biophys J (2006) 0.90
Relation between surface tension and ion adsorption at the air-water interface: a molecular dynamics simulation study. J Phys Chem A (2009) 0.90
Proton-coupled dynamics in lactose permease. Structure (2012) 0.89
Ion spatial distributions at the liquid-vapor interface of aqueous potassium fluoride solutions. Phys Chem Chem Phys (2008) 0.89
Reversible unfolding of beta-sheets in membranes: a calorimetric study. J Mol Biol (2004) 0.88
The low-temperature inflection observed in neutron scattering measurements of proteins is due to methyl rotation: direct evidence using isotope labeling and molecular dynamics simulations. J Am Chem Soc (2010) 0.88
Experimental and theoretical characterization of adsorbed water on self-assembled monolayers: understanding the interaction of water with atmospherically relevant surfaces. J Phys Chem A (2009) 0.88
Charge composition features of model single-span membrane proteins that determine selection of YidC and SecYEG translocase pathways in Escherichia coli. J Biol Chem (2013) 0.88
Microscopic wetting of mixed self-assembled monolayers: a molecular dynamics study. J Phys Chem B (2009) 0.87
Thermodynamics of iodide adsorption at the instantaneous air-water interface. J Chem Phys (2013) 0.87
Methyl group dynamics as a probe of the protein dynamical transition. J Am Chem Soc (2004) 0.87
Conformational states of melittin at a bilayer interface. Biophys J (2013) 0.86
Hydrogen bond dynamics in membrane protein function. Biochim Biophys Acta (2011) 0.86
Microscopic origin of gating current fluctuations in a potassium channel voltage sensor. Biophys J (2012) 0.86
Validation of depth-dependent fluorescence quenching in membranes by molecular dynamics simulation of tryptophan octyl ester in POPC bilayer. J Phys Chem B (2013) 0.86
Spatial dependence of protein-water collective hydrogen-bond dynamics. Phys Rev Lett (2013) 0.85
Ion specificity at the peptide bond: molecular dynamics simulations of N-methylacetamide in aqueous salt solutions. J Phys Chem B (2010) 0.84
Solvation of magnesium dication: molecular dynamics simulation and vibrational spectroscopic study of magnesium chloride in aqueous solutions. J Phys Chem A (2010) 0.83
Ser/Thr motifs in transmembrane proteins: conservation patterns and effects on local protein structure and dynamics. J Membr Biol (2012) 0.82
Molecular dynamics simulations of a pulmonary surfactant protein B peptide in a lipid monolayer. Biophys J (2003) 0.82
Inertial suppression of protein dynamics in a binary glycerol-trehalose glass. J Phys Chem B (2006) 0.82
A transporter converted into a sensor, a phototaxis signaling mutant of bacteriorhodopsin at 3.0 Å. J Mol Biol (2011) 0.82
Coupling between the voltage-sensing and pore domains in a voltage-gated potassium channel. Biochim Biophys Acta (2012) 0.82
Coupling of retinal, protein, and water dynamics in squid rhodopsin. Biophys J (2010) 0.82
Sensitivity of 2D IR spectra to peptide helicity: a concerted experimental and simulation study of an octapeptide. J Phys Chem B (2009) 0.81
Rhomboid intramembrane protease structures galore! Nat Struct Mol Biol (2006) 0.80
Re-examining the properties of the aqueous vapor-liquid interface using dispersion corrected density functional theory. J Chem Phys (2011) 0.80
Voltage Sensing in Membranes: From Macroscopic Currents to Molecular Motions. J Membr Biol (2015) 0.80
Structure of large nitrate-water clusters at ambient temperatures: simulations with effective fragment potentials and force fields with implications for atmospheric chemistry. J Phys Chem A (2009) 0.80
Structural dynamics of the S4 voltage-sensor helix in lipid bilayers lacking phosphate groups. J Phys Chem B (2011) 0.79
Crystal structure of cindoxin, the P450cin redox partner. Biochemistry (2014) 0.79
Nitrate ion photolysis in thin water films in the presence of bromide ions. J Phys Chem A (2011) 0.79
Dynamics of the internal water molecules in squid rhodopsin. Biophys J (2009) 0.79
Assembly and Stability of α-Helical Membrane Proteins. Soft Matter (2012) 0.79
Toward a unified picture of the water self-ions at the air-water interface: a density functional theory perspective. J Phys Chem B (2014) 0.79