Published in FASEB J on October 25, 2006
Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution. Science (2010) 3.03
Cortactin in tumor invasiveness. Cancer Lett (2008) 1.88
Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins. PLoS Biol (2009) 1.78
The roles of K(+) channels in cancer. Nat Rev Cancer (2013) 1.46
Cortactin: a multifunctional regulator of cellular invasiveness. Cell Adh Migr (2011) 1.36
Cytoplasmic BK(Ca) channel intron-containing mRNAs contribute to the intrinsic excitability of hippocampal neurons. Proc Natl Acad Sci U S A (2008) 1.20
TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology. Am J Physiol Renal Physiol (2010) 1.14
Nephrin binds to the COOH terminus of a large-conductance Ca2+-activated K+ channel isoform and regulates its expression on the cell surface. Am J Physiol Renal Physiol (2008) 1.11
Alternatively spliced C-terminal domains regulate the surface expression of large conductance calcium-activated potassium channels. Neuroscience (2007) 1.07
MAGI-1 interacts with Slo1 channel proteins and suppresses Slo1 expression on the cell surface. Am J Physiol Cell Physiol (2009) 1.04
MaxiK channel and cell signalling. Pflugers Arch (2014) 1.02
Cortactin is required for N-cadherin regulation of Kv1.5 channel function. J Biol Chem (2011) 1.00
Palmitoylation of the S0-S1 linker regulates cell surface expression of voltage- and calcium-activated potassium (BK) channels. J Biol Chem (2010) 0.98
Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain. J Mol Biol (2009) 0.96
Regulation of podocyte BK(Ca) channels by synaptopodin, Rho, and actin microfilaments. Am J Physiol Renal Physiol (2010) 0.93
Identification and quantification of full-length BK channel variants in the developing mouse cochlea. J Neurosci Res (2011) 0.91
Bin1 SRC homology 3 domain acts as a scaffold for myofiber sarcomere assembly. J Biol Chem (2009) 0.90
An alpha-catulin homologue controls neuromuscular function through localization of the dystrophin complex and BK channels in Caenorhabditis elegans. PLoS Genet (2010) 0.88
The RCC1 domain of protein associated with Myc (PAM) interacts with and regulates KCC2. Cell Physiol Biochem (2008) 0.88
Interactions between β-catenin and the HSlo potassium channel regulates HSlo surface expression. PLoS One (2011) 0.88
Neph1 regulates steady-state surface expression of Slo1 Ca(2+)-activated K(+) channels: different effects in embryonic neurons and podocytes. Am J Physiol Cell Physiol (2009) 0.86
The role of cell cholesterol and the cytoskeleton in the interaction between IK1 and maxi-K channels. Am J Physiol Cell Physiol (2009) 0.86
Cortactin controls surface expression of the voltage-gated potassium channel K(V)10.1. J Biol Chem (2012) 0.84
A graph kernel approach for alignment-free domain-peptide interaction prediction with an application to human SH3 domains. Bioinformatics (2013) 0.84
The beta1 subunit of Na+/K+-ATPase interacts with BKCa channels and affects their steady-state expression on the cell surface. FEBS Lett (2009) 0.84
Evidence of K+ channel function in epithelial cell migration, proliferation, and repair. Am J Physiol Cell Physiol (2013) 0.83
KCa1.1 inhibition attenuates fibroblast-like synoviocyte invasiveness and ameliorates disease in rat models of rheumatoid arthritis. Arthritis Rheumatol (2015) 0.82
Intrinsic disorder in the BK channel and its interactome. PLoS One (2014) 0.81
The C-terminus SH3-binding domain of Kv1.3 is required for the actin-mediated immobilization of the channel via cortactin. Mol Biol Cell (2015) 0.79
CDK5 interacts with Slo and affects its surface expression and kinetics through direct phosphorylation. Am J Physiol Cell Physiol (2011) 0.79
Interaction of tumour cells with their microenvironment: ion channels and cell adhesion molecules. A focus on pancreatic cancer. Philos Trans R Soc Lond B Biol Sci (2014) 0.78
Cyclin G2 promotes hypoxia-driven local invasion of glioblastoma by orchestrating cytoskeletal dynamics. Neoplasia (2013) 0.77
Ethanol Effect on BK Channels is Modulated by Magnesium. Alcohol Clin Exp Res (2015) 0.76
Evolution of the SH3 Domain Specificity Landscape in Yeasts. PLoS One (2015) 0.76
IRFinder: assessing the impact of intron retention on mammalian gene expression. Genome Biol (2017) 0.75
ERG-28 controls BK channel trafficking in the ER to regulate synaptic function and alcohol response in C. elegans. Elife (2017) 0.75
The large conductance calcium-activated potassium channel affects extrinsic and intrinsic mechanisms of apoptosis. J Neurosci Res (2015) 0.75
The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1. Neuron (2006) 3.17
Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases. Proc Natl Acad Sci U S A (2006) 3.13
Functional and spatial segregation of secretory vesicle pools according to vesicle age. Nature (2003) 2.55
BKCa-Cav channel complexes mediate rapid and localized Ca2+-activated K+ signaling. Science (2006) 2.40
Large-conductance calcium-activated potassium channel activity is absent in human and mouse neutrophils and is not required for innate immunity. Am J Physiol Cell Physiol (2007) 1.99
Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel-deficient mice. Circulation (2005) 1.80
Functionally diverse complement of large conductance calcium- and voltage-activated potassium channel (BK) alpha-subunits generated from a single site of splicing. J Biol Chem (2005) 1.78
Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss. Proc Natl Acad Sci U S A (2004) 1.67
Enhanced glucose tolerance by SK4 channel inhibition in pancreatic beta-cells. Diabetes (2009) 1.58
Ca2+ -activated K+ channels of the BK-type in the mouse brain. Histochem Cell Biol (2005) 1.46
Distinct stoichiometry of BKCa channel tetramer phosphorylation specifies channel activation and inhibition by cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (2004) 1.45
Palmitoylation gates phosphorylation-dependent regulation of BK potassium channels. Proc Natl Acad Sci U S A (2008) 1.41
A key role for gp130 expressed on peripheral sensory nerves in pathological pain. J Neurosci (2009) 1.37
Distal colonic K(+) secretion occurs via BK channels. J Am Soc Nephrol (2006) 1.35
Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model. J Neurosci (2008) 1.30
Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia. J Clin Invest (2004) 1.29
Dual role of protein kinase C on BK channel regulation. Proc Natl Acad Sci U S A (2010) 1.29
Aldosterone increases KCa1.1 (BK) channel-mediated colonic K+ secretion. J Physiol (2008) 1.24
Immunolocalization of BK channels in hippocampal pyramidal neurons. Eur J Neurosci (2006) 1.23
Differential expression of otoferlin in brain, vestibular system, immature and mature cochlea of the rat. Eur J Neurosci (2006) 1.21
Otoferlin interacts with myosin VI: implications for maintenance of the basolateral synaptic structure of the inner hair cell. Hum Mol Genet (2009) 1.21
Distinct acyl protein transferases and thioesterases control surface expression of calcium-activated potassium channels. J Biol Chem (2012) 1.21
A cysteine-rich motif confers hypoxia sensitivity to mammalian large conductance voltage- and Ca-activated K (BK) channel alpha-subunits. Proc Natl Acad Sci U S A (2005) 1.15
The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells. Hum Mol Genet (2006) 1.14
Endothelial dysfunction and blood pressure alterations in K+-channel transgenic mice. Pflugers Arch (2010) 1.13
Interacting effects of N-terminal variation and strex exon splicing on slo potassium channel regulation by calcium, phosphorylation, and oxidation. J Biol Chem (2002) 1.12
cGMP produced by NO-sensitive guanylyl cyclase essentially contributes to inflammatory and neuropathic pain by using targets different from cGMP-dependent protein kinase I. J Neurosci (2008) 1.10
The role of BKCa channels in electrical signal encoding in the mammalian auditory periphery. J Neurosci (2006) 1.10
Hierarchal type III secretion of translocators and effectors from Escherichia coli O157:H7 requires the carboxy terminus of SepL that binds to Tir. Mol Microbiol (2008) 1.10
Ionizing radiation, ion transports, and radioresistance of cancer cells. Front Physiol (2013) 1.09
Blunted IgE-mediated activation of mast cells in mice lacking the Ca2+-activated K+ channel KCa3.1. J Immunol (2008) 1.09
Conditional protein phosphorylation regulates BK channel activity in rat cerebellar Purkinje neurons. J Physiol (2003) 1.08
Disruption of the olivo-cerebellar circuit by Purkinje neuron-specific ablation of BK channels. Proc Natl Acad Sci U S A (2010) 1.07
Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca2+-activated K+ channel. FASEB J (2006) 1.07
BK channels in innate immune functions of neutrophils and macrophages. Blood (2008) 1.07
Increased large conductance calcium-activated potassium (BK) channel expression accompanied by STREX variant downregulation in the developing mouse CNS. BMC Dev Biol (2006) 1.07
Ca(v)1.3 and BK channels for timing and regulating cell firing. Mol Neurobiol (2010) 1.06
A novel isoform of SK2 assembles with other SK subunits in mouse brain. J Biol Chem (2005) 1.06
The vasodilator 17,18-epoxyeicosatetraenoic acid targets the pore-forming BK alpha channel subunit in rodents. Exp Physiol (2007) 1.04
Multiple palmitoyltransferases are required for palmitoylation-dependent regulation of large conductance calcium- and voltage-activated potassium channels. J Biol Chem (2010) 1.04
Inducible knockout mutagenesis reveals compensatory mechanisms elicited by constitutive BK channel deficiency in overactive murine bladder. FEBS J (2008) 1.04
Large-conductance calcium-activated potassium channels in purkinje cell plasma membranes are clustered at sites of hypolemmal microdomains. J Comp Neurol (2009) 1.02
M2 muscarinic receptors induce airway smooth muscle activation via a dual, Gbetagamma-mediated inhibition of large conductance Ca2+-activated K+ channel activity. J Biol Chem (2008) 1.01
Leucine zipper domain targets cAMP-dependent protein kinase to mammalian BK channels. J Biol Chem (2002) 1.01
TNF-alpha-mediates neuroprotection against glutamate-induced excitotoxicity via NF-kappaB-dependent up-regulation of K2.2 channels. J Neurochem (2008) 1.00
Ionizing radiation induces migration of glioblastoma cells by activating BK K(+) channels. Radiother Oncol (2011) 1.00
Mice with deficient BK channel function show impaired prepulse inhibition and spatial learning, but normal working and spatial reference memory. PLoS One (2013) 0.99
cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function. Nat Med (2012) 0.99
Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy. Brain Res (2008) 0.99
Palmitoylation of the S0-S1 linker regulates cell surface expression of voltage- and calcium-activated potassium (BK) channels. J Biol Chem (2010) 0.98
Dual effects of spinally delivered 8-bromo-cyclic guanosine mono-phosphate (8-bromo-cGMP) in formalin-induced nociception in rats. Neurosci Lett (2002) 0.98
Adrenaline-induced colonic K+ secretion is mediated by KCa1.1 (BK) channels. J Physiol (2010) 0.97
Reduced inflammatory hyperalgesia with preservation of acute thermal nociception in mice lacking cGMP-dependent protein kinase I. Proc Natl Acad Sci U S A (2004) 0.95
Neuronal functions, feeding behavior, and energy balance in Slc2a3+/- mice. Am J Physiol Endocrinol Metab (2008) 0.95
Selective expression in carotid body type I cells of a single splice variant of the large conductance calcium- and voltage-activated potassium channel confers regulation by AMP-activated protein kinase. J Biol Chem (2011) 0.94
Palmitoylation and membrane association of the stress axis regulated insert (STREX) controls BK channel regulation by protein kinase C. J Biol Chem (2012) 0.92
Pre-synaptic BK channels selectively control glutamate versus GABA release from cortical and hippocampal nerve terminals. J Neurochem (2010) 0.92
A high-capacity membrane potential FRET-based assay for NaV1.8 channels. Assay Drug Dev Technol (2006) 0.92
CD31 delays phagocyte membrane repolarization to promote efficient binding of apoptotic cells. J Leukoc Biol (2007) 0.90
Neuronal Ca2+-activated K+ channels limit brain infarction and promote survival. PLoS One (2010) 0.90
Protease and pro-inflammatory cytokine concentrations are elevated in chronic compared to acute wounds and can be modulated by collagen type I in vitro. Arch Dermatol Res (2009) 0.90
Rab8b GTPase, a protein transport regulator, is an interacting partner of otoferlin, defective in a human autosomal recessive deafness form. Hum Mol Genet (2008) 0.90
An electrostatic switch controls palmitoylation of the large conductance voltage- and calcium-activated potassium (BK) channel. J Biol Chem (2011) 0.90
Surface expression, single-channel analysis and membrane topology of recombinant Chlamydia trachomatis Major Outer Membrane Protein. BMC Microbiol (2005) 0.89
Otoferlin couples to clathrin-mediated endocytosis in mature cochlear inner hair cells. J Neurosci (2013) 0.89
Heme oxygenase-2 and large-conductance Ca2+-activated K+ channels: lung vascular effects of hypoxia. Am J Respir Crit Care Med (2009) 0.89
The hemocyanin from a living fossil, the cephalopod Nautilus pompilius: protein structure, gene organization, and evolution. J Mol Evol (2006) 0.88
Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wlds) gene. Mol Neurodegener (2007) 0.88
Deafness in TRbeta mutants is caused by malformation of the tectorial membrane. J Neurosci (2009) 0.88