Published in J Physiol on March 29, 2010
Large conductance, calcium- and voltage-gated potassium (BK) channels: regulation by cholesterol. Pharmacol Ther (2012) 0.96
Rescue of epithelial HCO3- secretion in murine intestine by apical membrane expression of the cystic fibrosis transmembrane conductance regulator mutant F508del. J Physiol (2012) 0.88
Large conductance Ca(2+) -activated K(+) channel activation by apical P2Y receptor agonists requires hydrocortisone in differentiated airway epithelium. J Physiol (2017) 0.88
Role of the BK channel (KCa1.1) during activation of electrogenic K+ secretion in guinea pig distal colon. Am J Physiol Gastrointest Liver Physiol (2012) 0.83
Molecular basis of potassium channels in pancreatic duct epithelial cells. Channels (Austin) (2013) 0.83
Hypokalemia Associated with Colonic Pseudo-Obstruction (Ogilvie's Syndrome). Case Rep Nephrol Dial (2015) 0.83
Properties of cholinergic and non-cholinergic submucosal neurons along the mouse colon. J Physiol (2013) 0.80
The secretory KCa1.1 channel localises to crypts of distal mouse colon: functional and molecular evidence. Pflugers Arch (2011) 0.80
A tale from the Crypt: splice variants of BK channels in colonic potassium secretion. J Physiol (2010) 0.75
Intact colonic KCa1.1 channel activity in KCNMB2 knockout mice. Physiol Rep (2017) 0.75
High-conductance potassium channels of the SLO family. Nat Rev Neurosci (2006) 4.26
Electrolyte transport in the mammalian colon: mechanisms and implications for disease. Physiol Rev (2002) 3.10
Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency. Proc Natl Acad Sci U S A (2004) 2.97
Crypts are the site of intestinal fluid and electrolyte secretion. Science (1982) 2.66
Protein kinases: tuners of the BKCa channel in smooth muscle. Trends Pharmacol Sci (2001) 2.48
Control of alternative splicing of potassium channels by stress hormones. Science (1998) 2.35
Alternative splicing switches potassium channel sensitivity to protein phosphorylation. J Biol Chem (2001) 1.95
Current-voltage curve of sodium channels and concentration dependence of sodium permeability in frog skin. J Physiol (1977) 1.83
Functionally diverse complement of large conductance calcium- and voltage-activated potassium channel (BK) alpha-subunits generated from a single site of splicing. J Biol Chem (2005) 1.78
Increased survival of CFTR knockout mice with an oral osmotic laxative. Lab Anim Sci (1996) 1.43
Distal colonic K(+) secretion occurs via BK channels. J Am Soc Nephrol (2006) 1.35
Basolateral localization of native ClC-2 chloride channels in absorptive intestinal epithelial cells and basolateral sorting encoded by a CBS-2 domain di-leucine motif. J Cell Sci (2005) 1.33
Active K transport across rabbit distal colon: relation to Na absorption and Cl secretion. Am J Physiol (1986) 1.24
Aldosterone increases KCa1.1 (BK) channel-mediated colonic K+ secretion. J Physiol (2008) 1.24
Segment-specific effects of epinephrine on ion transport in the colon of the rat. Am J Physiol (1998) 1.21
Characterization of aldosterone-induced potassium secretion in rat distal colon. J Clin Invest (1989) 1.19
Abolition of Ca2+-mediated intestinal anion secretion and increased stool dehydration in mice lacking the intermediate conductance Ca2+-dependent K+ channel Kcnn4. J Physiol (2007) 1.11
Alternative splicing determines sensitivity of murine calcium-activated potassium channels to glucocorticoids. J Physiol (2001) 1.05
Characterization of apical potassium channels induced in rat distal colon during potassium adaptation. J Physiol (1997) 1.02
Role of aldosterone and dietary potassium in potassium adaptation in the distal colon of the rat. Gastroenterology (1985) 1.01
Regulation of apical and basolateral K+ conductances in rat colon. Br J Pharmacol (1997) 0.99
Emerging insights into the coactivator role of NCoA62/SKIP in Vitamin D-mediated transcription. J Steroid Biochem Mol Biol (2004) 0.98
ATP increases [Ca2+]i and ion secretion via a basolateral P2Y-receptor in rat distal colonic mucosa. Pflugers Arch (1997) 0.97
Active potassium transport across guinea-pig distal colon: action of secretagogues. J Physiol (1996) 0.93
Molecular and functional identification of cyclic AMP-sensitive BKCa potassium channels (ZERO variant) and L-type voltage-dependent calcium channels in single rat juxtaglomerular cells. Circ Res (2003) 0.92
Cyclic adenosine monophosphate stimulates active potassium secretion in the rat colon. Gastroenterology (1983) 0.91
Aldosterone stimulates K secretion across mammalian colon independent of Na absorption. Proc Natl Acad Sci U S A (1989) 0.88
Aldosterone induction and epithelial distribution of CHIF. Am J Physiol (1996) 0.85
Adrenergic influences on the electrical potential across the colonic mucosa of the rabbit. J Physiol (1975) 0.84
Localization of cAMP- and aldosterone-induced K+ secretion in rat distal colon by conductance scanning. J Physiol (1998) 0.83
Rectal potential difference and the functional expression of CFTR in the gastrointestinal epithelia in cystic fibrosis mouse models. Pediatr Res (2008) 0.82
Activation of apical K+ conductances by muscarinic receptor stimulation in rat distal colon: fast and slow components. J Membr Biol (2003) 0.81
beta-adrenergic agonists stimulate Na+-K+-Cl- cotransport by inducing intracellular Ca2+ liberation in crypt cells. Am J Physiol (1999) 0.79
Large-conductance calcium-activated potassium channel activity is absent in human and mouse neutrophils and is not required for innate immunity. Am J Physiol Cell Physiol (2007) 1.99
Intravenous iron sucrose versus oral iron supplementation for the treatment of iron deficiency anemia in patients with inflammatory bowel disease--a randomized, controlled, open-label, multicenter study. Am J Gastroenterol (2005) 1.93
Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity. PLoS One (2007) 1.86
Fructose-induced hypertension: essential role of chloride and fructose absorbing transporters PAT1 and Glut5. Kidney Int (2008) 1.80
Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel-deficient mice. Circulation (2005) 1.80
ATP release from non-excitable cells. Purinergic Signal (2009) 1.78
Functionally diverse complement of large conductance calcium- and voltage-activated potassium channel (BK) alpha-subunits generated from a single site of splicing. J Biol Chem (2005) 1.78
Renal and intestinal transport defects in Slc26a6-null mice. Am J Physiol Cell Physiol (2004) 1.68
Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss. Proc Natl Acad Sci U S A (2004) 1.67
Flow-induced [Ca2+]i increase depends on nucleotide release and subsequent purinergic signaling in the intact nephron. J Am Soc Nephrol (2007) 1.59
Enhanced glucose tolerance by SK4 channel inhibition in pancreatic beta-cells. Diabetes (2009) 1.58
Autocrine purinergic receptor signaling is essential for macrophage chemotaxis. Sci Signal (2010) 1.52
Interaction between Na+/K+-pump and Na+/Ca2+-exchanger modulates intercellular communication. Circ Res (2007) 1.50
Down-regulated in adenoma mediates apical Cl-/HCO3- exchange in rabbit, rat, and human duodenum. Gastroenterology (2002) 1.47
The role of pancreatic ductal secretion in protection against acute pancreatitis in mice*. Crit Care Med (2014) 1.46
Ca2+ -activated K+ channels of the BK-type in the mouse brain. Histochem Cell Biol (2005) 1.46
Distinct stoichiometry of BKCa channel tetramer phosphorylation specifies channel activation and inhibition by cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (2004) 1.45
Na⁺/H⁺ exchanger regulatory factor 3 is critical for multidrug resistance protein 4-mediated drug efflux in the kidney. J Am Soc Nephrol (2014) 1.41
Palmitoylation gates phosphorylation-dependent regulation of BK potassium channels. Proc Natl Acad Sci U S A (2008) 1.41
Distal colonic K(+) secretion occurs via BK channels. J Am Soc Nephrol (2006) 1.35
Lysophosphatidic acid stimulates the intestinal brush border Na(+)/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF2. Gastroenterology (2009) 1.33
A noncanonical SH3 domain binding motif links BK channels to the actin cytoskeleton via the SH3 adapter cortactin. FASEB J (2006) 1.31
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice. J Clin Invest (2009) 1.30
Alpha-hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis. Proc Natl Acad Sci U S A (2009) 1.30
Isoforms of SLC26A6 mediate anion transport and have functional PDZ interaction domains. Am J Physiol Cell Physiol (2002) 1.29
Dual role of protein kinase C on BK channel regulation. Proc Natl Acad Sci U S A (2010) 1.29
The role of the NHERF family of PDZ scaffolding proteins in the regulation of salt and water transport. Ann N Y Acad Sci (2009) 1.26
Slc2a5 (Glut5) is essential for the absorption of fructose in the intestine and generation of fructose-induced hypertension. J Biol Chem (2008) 1.25
The down regulated in adenoma (dra) gene product binds to the second PDZ domain of the NHE3 kinase A regulatory protein (E3KARP), potentially linking intestinal Cl-/HCO3- exchange to Na+/H+ exchange. Biochemistry (2002) 1.24
Luminal P2Y2 receptor-mediated inhibition of Na+ absorption in isolated perfused mouse CCD. J Am Soc Nephrol (2002) 1.24
Aldosterone increases KCa1.1 (BK) channel-mediated colonic K+ secretion. J Physiol (2008) 1.24
Immunolocalization of BK channels in hippocampal pyramidal neurons. Eur J Neurosci (2006) 1.23
Differential expression of otoferlin in brain, vestibular system, immature and mature cochlea of the rat. Eur J Neurosci (2006) 1.21
Otoferlin interacts with myosin VI: implications for maintenance of the basolateral synaptic structure of the inner hair cell. Hum Mol Genet (2009) 1.21
Distinct acyl protein transferases and thioesterases control surface expression of calcium-activated potassium channels. J Biol Chem (2012) 1.21
NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes. J Physiol (2007) 1.20
Deletion of the chloride transporter Slc26a9 causes loss of tubulovesicles in parietal cells and impairs acid secretion in the stomach. Proc Natl Acad Sci U S A (2008) 1.18
Involvement of the anion exchanger SLC26A6 in prostaglandin E2- but not forskolin-stimulated duodenal HCO3- secretion. Gastroenterology (2006) 1.17
D-glucose acts via sodium/glucose cotransporter 1 to increase NHE3 in mouse jejunal brush border by a Na+/H+ exchange regulatory factor 2-dependent process. Gastroenterology (2010) 1.16
Intrarenal purinergic signaling in the control of renal tubular transport. Annu Rev Physiol (2010) 1.15
Basolateral Na+-dependent HCO3- transporter NBCn1-mediated HCO3- influx in rat medullary thick ascending limb. J Physiol (2003) 1.13
Endothelial dysfunction and blood pressure alterations in K+-channel transgenic mice. Pflugers Arch (2010) 1.13
Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice. J Biol Chem (2007) 1.11
cGMP produced by NO-sensitive guanylyl cyclase essentially contributes to inflammatory and neuropathic pain by using targets different from cGMP-dependent protein kinase I. J Neurosci (2008) 1.10
The role of BKCa channels in electrical signal encoding in the mammalian auditory periphery. J Neurosci (2006) 1.10
Ionizing radiation, ion transports, and radioresistance of cancer cells. Front Physiol (2013) 1.09
Blunted IgE-mediated activation of mast cells in mice lacking the Ca2+-activated K+ channel KCa3.1. J Immunol (2008) 1.09
The switch of intestinal Slc26 exchangers from anion absorptive to HCOFormula secretory mode is dependent on CFTR anion channel function. Am J Physiol Cell Physiol (2010) 1.08
Colonic potassium handling. Pflugers Arch (2010) 1.08
Disruption of the olivo-cerebellar circuit by Purkinje neuron-specific ablation of BK channels. Proc Natl Acad Sci U S A (2010) 1.07
Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca2+-activated K+ channel. FASEB J (2006) 1.07
BK channels in innate immune functions of neutrophils and macrophages. Blood (2008) 1.07
Increased large conductance calcium-activated potassium (BK) channel expression accompanied by STREX variant downregulation in the developing mouse CNS. BMC Dev Biol (2006) 1.07
Ca(v)1.3 and BK channels for timing and regulating cell firing. Mol Neurobiol (2010) 1.06
Down regulation of small intestinal ion transport in PDZK1- (CAP70/NHERF3) deficient mice. Pflugers Arch (2007) 1.06
Knockout mouse models for intestinal electrolyte transporters and regulatory PDZ adaptors: new insights into cystic fibrosis, secretory diarrhoea and fructose-induced hypertension. Exp Physiol (2008) 1.06
Loss of downregulated in adenoma (DRA) impairs mucosal HCO3(-) secretion in murine ileocolonic inflammation. Inflamm Bowel Dis (2011) 1.05
Gp130 signaling promotes development of acute experimental colitis by facilitating early neutrophil/macrophage recruitment and activation. J Immunol (2008) 1.05
The vasodilator 17,18-epoxyeicosatetraenoic acid targets the pore-forming BK alpha channel subunit in rodents. Exp Physiol (2007) 1.04
Molecular mechanisms of disturbed electrolyte transport in intestinal inflammation. Ann N Y Acad Sci (2006) 1.04
P2Y6 receptor mediates colonic NaCl secretion via differential activation of cAMP-mediated transport. J Clin Invest (2003) 1.04
Sodium and chloride absorptive defects in the small intestine in Slc26a6 null mice. Pflugers Arch (2007) 1.04
Inducible knockout mutagenesis reveals compensatory mechanisms elicited by constitutive BK channel deficiency in overactive murine bladder. FEBS J (2008) 1.04
Loss of PDZ-adaptor protein NHERF2 affects membrane localization and cGMP- and [Ca2+]- but not cAMP-dependent regulation of Na+/H+ exchanger 3 in murine intestine. J Physiol (2010) 1.04
New therapeutic targets in ulcerative colitis: the importance of ion transporters in the human colon. Inflamm Bowel Dis (2010) 1.03
Vasopressin-independent targeting of aquaporin-2 by selective E-prostanoid receptor agonists alleviates nephrogenic diabetes insipidus. Proc Natl Acad Sci U S A (2011) 1.02
Large-conductance calcium-activated potassium channels in purkinje cell plasma membranes are clustered at sites of hypolemmal microdomains. J Comp Neurol (2009) 1.02
Transient P2X7 receptor activation triggers macrophage death independent of Toll-like receptors 2 and 4, caspase-1, and pannexin-1 proteins. J Biol Chem (2012) 1.01
M2 muscarinic receptors induce airway smooth muscle activation via a dual, Gbetagamma-mediated inhibition of large conductance Ca2+-activated K+ channel activity. J Biol Chem (2008) 1.01
Knock-out mice reveal the contributions of P2Y and P2X receptors to nucleotide-induced Ca2+ signaling in macrophages. J Biol Chem (2006) 1.01