Published in Biol Chem on November 03, 2006
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Novel domain combinations in proteins encoded by chimeric transcripts. Bioinformatics (2012) 0.96
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Filamins: promiscuous organizers of the cytoskeleton. Trends Biochem Sci (2006) 2.79
High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx. Cell Cycle (2009) 2.11
Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain. Cell Cycle (2008) 1.71
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Structure of the stapled p53 peptide bound to Mdm2. J Am Chem Soc (2011) 1.30
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The crystal structure of the non-liganded 14-3-3sigma protein: insights into determinants of isoform specific ligand binding and dimerization. Cell Res (2005) 1.13
Molecular determinants for the complex formation between the retinoblastoma protein and LXCXE sequences. J Biol Chem (2005) 1.12
Molecular structure of the rod domain of dictyostelium filamin. J Mol Biol (2004) 1.12
Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proc Natl Acad Sci U S A (2006) 1.11
Active detachment involves inhibition of cell-matrix contacts of malignant melanoma cells by secretion of melanoma inhibitory activity. Lab Invest (2003) 1.10
NMR indicates that the small molecule RITA does not block p53-MDM2 binding in vitro. Nat Med (2005) 1.09
c-Abl phosphorylates Hdmx and regulates its interaction with p53. J Biol Chem (2008) 1.09
Structural ramification for acetyl-lysine recognition by the bromodomain of human BRG1 protein, a central ATPase of the SWI/SNF remodeling complex. Chembiochem (2007) 1.09
Backbone dynamics of green fluorescent protein and the effect of histidine 148 substitution. Biochemistry (2003) 1.08
Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing. Nature (2011) 1.07
Characterization of 14-3-3sigma dimerization determinants: requirement of homodimerization for inhibition of cell proliferation. Cell Cycle (2006) 1.07
1,4-Thienodiazepine-2,5-diones via MCR (I): synthesis, virtual space and p53-Mdm2 activity. Chem Biol Drug Des (2010) 1.07
Shugoshin is a Mad1/Cdc20-like interactor of Mad2. EMBO J (2011) 1.06
Rapid and efficient hydrophilicity tuning of p53/mdm2 antagonists. J Comb Chem (2010) 1.03
Slow exchange in the chromophore of a green fluorescent protein variant. J Am Chem Soc (2002) 1.02
Exhaustive fluorine scanning toward potent p53-Mdm2 antagonists. ChemMedChem (2011) 1.01
Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation. Proc Natl Acad Sci U S A (2010) 1.00
Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization. J Mol Biol (2006) 0.99
Monitoring the effects of antagonists on protein-protein interactions with NMR spectroscopy. J Am Chem Soc (2005) 0.96
Structural basis for the regulation of insulin-like growth factors by IGF binding proteins. Structure (2005) 0.95
Robust NMR screening for lead compounds using tryptophan-containing proteins. J Am Chem Soc (2009) 0.95
A novel medium for expression of proteins selectively labeled with 15N-amino acids in Spodoptera frugiperda (Sf9) insect cells. J Biomol NMR (2003) 0.95
Functional and structural characterization of Spl proteases from Staphylococcus aureus. J Mol Biol (2006) 0.95
An NMR-based antagonist induced dissociation assay for targeting the ligand-protein and protein-protein interactions in competition binding experiments. J Med Chem (2007) 0.94
Mdm2 and MdmX inhibitors for the treatment of cancer: a patent review (2011-present). Expert Opin Ther Pat (2013) 0.91
Programmed death-1: therapeutic success after more than 100 years of cancer immunotherapy. Angew Chem Int Ed Engl (2014) 0.91
Ablation of cyclase-associated protein 2 (CAP2) leads to cardiomyopathy. Cell Mol Life Sci (2012) 0.91
Structure of the N-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum. Structure (2003) 0.89
The three-dimensional structures of tick carboxypeptidase inhibitor in complex with A/B carboxypeptidases reveal a novel double-headed binding mode. J Mol Biol (2005) 0.88
Discovery of highly potent p53-MDM2 antagonists and structural basis for anti-acute myeloid leukemia activities. ACS Chem Biol (2014) 0.87
Filamin-regulated F-actin assembly is essential for morphogenesis and controls phototaxis in Dictyostelium. J Biol Chem (2006) 0.87
Efforts towards the design of 'teflon' proteins: in vivo translation with trifluorinated leucine and methionine analogues. Chem Biodivers (2004) 0.86
A novel class of cysteine protease inhibitors: solution structure of staphostatin A from Staphylococcus aureus. Biochemistry (2003) 0.83
Identification of calpain cleavage sites in the G1 cyclin-dependent kinase inhibitor p19(INK4d). Biol Chem (2006) 0.82
Gadolinium oxide ultranarrow nanorods as multimodal contrast agents for optical and magnetic resonance imaging. Langmuir (2010) 0.81
Backbone H(N), N, C(alpha) and C(beta) assignment of the GFPuv mutant. J Biomol NMR (2003) 0.81
NMR structural characterization of the N-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum. J Biomol NMR (2004) 0.81
In silico and NMR identification of inhibitors of the IGF-I and IGF-binding protein-5 interaction. J Med Chem (2002) 0.80
Molecular architecture of the Spire-actin nucleus and its implication for actin filament assembly. Proc Natl Acad Sci U S A (2011) 0.80
Purification, crystallization, NMR spectroscopy and biochemical analyses of alpha-phycoerythrocyanin peptides. Eur J Biochem (2002) 0.80
NMR screening for lead compounds using tryptophan-mutated proteins. J Med Chem (2008) 0.80
Structural and functional analysis of the natural JNK1 inhibitor quercetagetin. J Mol Biol (2012) 0.79
Selective targeting of disease-relevant protein binding domains by O-phosphorylated natural product derivatives. ACS Chem Biol (2011) 0.79
Benzimidazole-2-one: a novel anchoring principle for antagonizing p53-Mdm2. Bioorg Med Chem (2012) 0.78
Fragment-based library generation for the discovery of a peptidomimetic p53-Mdm4 inhibitor. ACS Comb Sci (2014) 0.78
Backbone dynamics of the human MIA protein studied by (15)N NMR relaxation: implications for extended interactions of SH3 domains. Protein Sci (2003) 0.78
NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor. Structure (2005) 0.78
NMR and mass spectrometry studies of putative interactions of cell cycle proteins pRb and CDK6 with cell differentiation proteins MyoD and ID-2. Biochim Biophys Acta (2005) 0.78
Phosphorylation and flexibility of cyclic-AMP-dependent protein kinase (PKA) using (31)P NMR spectroscopy. Biochemistry (2002) 0.77
Proteolysis of insulin-like growth factor binding proteins (IGFBPs) by calpain. Biol Chem (2005) 0.76
2,30-Bis(10H-indole) heterocycles: New p53/MDM2/MDMX antagonists. Bioorg Med Chem Lett (2015) 0.76
Structures of the arm-type binding domains of HPI and HAI7 integrases. J Biol Chem (2009) 0.75
1H, 15N and 13C NMR resonance assignments of staphostatin A, a specific Staphylococcus aureus cysteine proteinase inhibitor. J Biomol NMR (2004) 0.75
Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond. J Mol Biol (2005) 0.75
Immune Checkpoint PD-1/PD-L1: Is There Life Beyond Antibodies? Angew Chem Int Ed Engl (2017) 0.75
1,4,5-Trisubstituted Imidazole-Based p53-MDM2/MDMX Antagonists with Aliphatic Linkers for Conjugation with Biological Carriers. J Med Chem (2017) 0.75
Sequence-specific (1H, 15N, 13C) resonance assignment of the N-terminal domain of the cyclase-associated protein (CAP) from Dictyostelium discoideum. J Biomol NMR (2002) 0.75