Published in Angew Chem Int Ed Engl on November 13, 2006
Droplet microfluidic technology for single-cell high-throughput screening. Proc Natl Acad Sci U S A (2009) 3.85
Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins. Proc Natl Acad Sci U S A (2006) 2.66
Controlled encapsulation of single-cells into monodisperse picolitre drops. Lab Chip (2008) 2.48
Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidics. Lab Chip (2008) 2.11
High-throughput injection with microfluidics using picoinjectors. Proc Natl Acad Sci U S A (2010) 2.07
Microfluidic confinement of single cells of bacteria in small volumes initiates high-density behavior of quorum sensing and growth and reveals its variability. Angew Chem Int Ed Engl (2009) 1.99
The chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution. Proc Natl Acad Sci U S A (2008) 1.90
SlipChip. Lab Chip (2009) 1.84
Digital PCR on a SlipChip. Lab Chip (2010) 1.57
Control and measurement of the phase behavior of aqueous solutions using microfluidics. J Am Chem Soc (2007) 1.44
Surface molecular property modifications for poly(dimethylsiloxane) (PDMS) based microfluidic devices. Microfluid Nanofluidics (2009) 1.40
Chemistry and biology in femtoliter and picoliter volume droplets. Acc Chem Res (2009) 1.35
Development of an automated microfluidic reaction platform for multidimensional screening: reaction discovery employing bicyclo[3.2.1]octanoid scaffolds. J Org Chem (2009) 1.34
Theoretical design and analysis of multivolume digital assays with wide dynamic range validated experimentally with microfluidic digital PCR. Anal Chem (2011) 1.32
Nanoliter multiplex PCR arrays on a SlipChip. Anal Chem (2010) 1.30
Nanofluidic concentration devices for biomolecules utilizing ion concentration polarization: theory, fabrication, and applications. Chem Soc Rev (2010) 1.26
Microfluidics as a functional tool for cell mechanics. Biomicrofluidics (2009) 1.22
Recent trends in microdialysis sampling integrated with conventional and microanalytical systems for monitoring biological events: a review. Anal Chim Acta (2009) 1.21
Using a multijunction microfluidic device to inject substrate into an array of preformed plugs without cross-contamination: comparing theory and experiments. Anal Chem (2007) 1.20
Dispensing nano-pico droplets and liquid patterning by pyroelectrodynamic shooting. Nat Nanotechnol (2010) 1.19
Picoinjection enables digital detection of RNA with droplet rt-PCR. PLoS One (2013) 1.19
Sampling and electrophoretic analysis of segmented flow streams using virtual walls in a microfluidic device. Anal Chem (2008) 1.18
Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA. Mol Ther Nucleic Acids (2012) 1.16
SlipChip for immunoassays in nanoliter volumes. Anal Chem (2010) 1.13
Compartmentalization of chemically separated components into droplets. Angew Chem Int Ed Engl (2009) 1.11
Rate of mixing controls rate and outcome of autocatalytic processes: theory and microfluidic experiments with chemical reactions and blood coagulation. Biophys J (2008) 1.11
Microfluidic stochastic confinement enhances analysis of rare cells by isolating cells and creating high density environments for control of diffusible signals. Chem Soc Rev (2010) 1.10
Real-time detection, control, and sorting of microfluidic droplets. Biomicrofluidics (2007) 1.08
An on-chip, multichannel droplet sorter using standing surface acoustic waves. Anal Chem (2013) 1.08
Evolution of catalysts directed by genetic algorithms in a plug-based microfluidic device tested with oxidation of methane by oxygen. J Am Chem Soc (2010) 1.07
Micro-chemical synthesis of molecular probes on an electronic microfluidic device. Proc Natl Acad Sci U S A (2011) 1.07
Counting single molecules in sub-nanolitre droplets. Lab Chip (2009) 1.07
Droplet microfluidics driven by gradients of confinement. Proc Natl Acad Sci U S A (2013) 1.07
A practical guide to the staggered herringbone mixer. Lab Chip (2008) 1.06
Analysis of samples stored as individual plugs in a capillary by electrospray ionization mass spectrometry. Anal Chem (2009) 1.06
Single-shot characterization of enzymatic reaction constants Km and kcat by an acoustic-driven, bubble-based fast micromixer. Anal Chem (2012) 1.06
User-loaded SlipChip for equipment-free multiplexed nanoliter-scale experiments. J Am Chem Soc (2010) 1.04
Polymer nanofibre junctions of attolitre volume serve as zeptomole-scale chemical reactors. Nat Chem (2009) 1.03
Dripping and jetting in microfluidic multiphase flows applied to particle and fiber synthesis. J Phys D Appl Phys (2013) 1.03
Quantum dot-based theranostics. Nanoscale (2009) 1.03
Push-pull perfusion sampling with segmented flow for high temporal and spatial resolution in vivo chemical monitoring. Anal Chem (2011) 1.02
Laterally mobile, functionalized self-assembled monolayers at the fluorous-aqueous interface in a plug-based microfluidic system: characterization and testing with membrane protein crystallization. J Am Chem Soc (2009) 1.02
Tuning physical properties of nanocomplexes through microfluidics-assisted confinement. Nano Lett (2011) 1.00
Field-free particle focusing in microfluidic plugs. Biomicrofluidics (2012) 0.98
Continuous-flow catalytic asymmetric hydrogenations: Reaction optimization using FTIR inline analysis. Beilstein J Org Chem (2012) 0.98
Mixing subattolitre volumes in a quantitative and highly parallel manner with soft matter nanofluidics. Nat Nanotechnol (2011) 0.98
A droplet-based, optofluidic device for high-throughput, quantitative bioanalysis. Anal Chem (2012) 0.97
Plug-based microfluidics with defined surface chemistry to miniaturize and control aggregation of amyloidogenic peptides. Angew Chem Int Ed Engl (2009) 0.97
Opportunities for microfluidic technologies in synthetic biology. J R Soc Interface (2009) 0.97
Microfluidic systems for biosensing. Sensors (Basel) (2010) 0.96
Surface patterning of bonded microfluidic channels. Biomicrofluidics (2010) 0.96
Behavior of a train of droplets in a fluidic network with hydrodynamic traps. Biomicrofluidics (2010) 0.96
Microfluidic platform for on-demand generation of spatially indexed combinatorial droplets. Lab Chip (2012) 0.95
Ultralocalized thermal reactions in subnanoliter droplets-in-air. Proc Natl Acad Sci U S A (2013) 0.95
Microfluidic sample preparation for diagnostic cytopathology. Lab Chip (2013) 0.95
A Plug-Based Microfluidic System for Dispensing Lipidic Cubic Phase (LCP) Material Validated by Crystallizing Membrane Proteins in Lipidic Mesophases. Microfluid Nanofluidics (2010) 0.93
Review of methods to probe single cell metabolism and bioenergetics. Metab Eng (2014) 0.92
Microfluidic-based 18F-labeling of biomolecules for immuno-positron emission tomography. Mol Imaging (2011) 0.92
Development and optimization of an integrated PDMS based-microdialysis microchip electrophoresis device with on-chip derivatization for continuous monitoring of primary amines. Electrophoresis (2013) 0.91
Development and fabrication of nanoporous silicon-based bioreactors within a microfluidic chip. Lab Chip (2010) 0.91
Microvalve Enabled Digital Microfluidic Systems for High Performance Biochemical and Genetic Analysis. JALA Charlottesv Va (2010) 0.91
Oil-sealed femtoliter fiber-optic arrays for single molecule analysis. Lab Chip (2012) 0.91
Simple host-guest chemistry to modulate the process of concentration and crystallization of membrane proteins by detergent capture in a microfluidic device. J Am Chem Soc (2008) 0.90
Simultaneous generation of multiple aqueous droplets in a microfluidic device. Anal Chim Acta (2008) 0.90
Controlled multistep synthesis in a three-phase droplet reactor. Nat Commun (2014) 0.89
Droplets formation and merging in two-phase flow microfluidics. Int J Mol Sci (2011) 0.89
Sizing subcellular organelles and nanoparticles confined within aqueous droplets. Anal Chem (2008) 0.89
On-chip magnetic separation and encapsulation of cells in droplets. Lab Chip (2013) 0.89
Electrowetting --a versatile tool for controlling microdrop generation. Eur Phys J E Soft Matter (2008) 0.89
Enhancing protease activity assay in droplet-based microfluidics using a biomolecule concentrator. J Am Chem Soc (2011) 0.88
Microfluidics: reframing biological enquiry. Nat Rev Mol Cell Biol (2015) 0.87
Vimentin networks at tunable ion-concentration in microfluidic drops. Biomicrofluidics (2012) 0.87
Challenges and opportunities for new protein crystallization strategies in structure-based drug design. Expert Opin Drug Discov (2010) 0.86
Ionic liquid flow along the carbon nanotube with DC electric field. Sci Rep (2015) 0.86
Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis. Proc Natl Acad Sci U S A (2014) 0.86
Using chemistry and microfluidics to understand the spatial dynamics of complex biological networks. Acc Chem Res (2008) 0.85
A digital microfluidic droplet generator produces self-assembled supramolecular nanoparticles for targeted cell imaging. Nanotechnology (2010) 0.85
Single-Cell Analysis of [18F]Fluorodeoxyglucose Uptake by Droplet Radiofluidics. Anal Chem (2015) 0.85
Remotely controllable liquid marbles. Adv Mater (2012) 0.85
Online coupling of digital microfluidic devices with mass spectrometry detection using an eductor with electrospray ionization. Anal Chem (2012) 0.85
Cofabrication: a strategy for building multicomponent microsystems. Acc Chem Res (2010) 0.84
Microfluidics for positron emission tomography probe development. Mol Imaging (2010) 0.84
Digitally programmable microfluidic automaton for multiscale combinatorial mixing and sample processing. Lab Chip (2012) 0.84
The convergence of quantum-dot-mediated fluorescence resonance energy transfer and microfluidics for monitoring DNA polyplex self-assembly in real time. Nanotechnology (2009) 0.84
Oil-isolated hydrogel microstructures for sensitive bioassays on-chip. Anal Chem (2013) 0.84
Detecting and tracking nosocomial methicillin-resistant Staphylococcus aureus using a microfluidic SERS biosensor. Anal Chem (2013) 0.83
Nanowire liquid pumps. Nat Nanotechnol (2013) 0.83
Microfluidic device for robust generation of two-component liquid-in-air slugs with individually controlled composition. Microfluid Nanofluidics (2010) 0.83
Use of a corona discharge to selectively pattern a hydrophilic/hydrophobic interface for integrating segmented flow with microchip electrophoresis and electrochemical detection. Anal Chem (2011) 0.82
Controlling droplet incubation using close-packed plug flow. Biomicrofluidics (2011) 0.82
Interfacial nano-biosensing in microfluidic droplets for high-sensitivity detection of low-solubility molecules. Chem Commun (Camb) (2016) 0.82
DNA sequence analysis with droplet-based microfluidics. Lab Chip (2013) 0.82
Theta-glass capillaries in electrospray ionization: rapid mixing and short droplet lifetimes. Anal Chem (2014) 0.82
A new microfluidics-based droplet dispenser for ICPMS. Anal Chem (2014) 0.81
Controlled generation of double emulsions in air. Anal Chem (2013) 0.81
Synthesis of fluorosurfactants for emulsion-based biological applications. ACS Nano (2014) 0.81
Controlled dispensing and mixing of pico- to nanoliter volumes using on-demand droplet-based microfluidics. Microfluid Nanofluidics (2013) 0.81
Microdroplet fusion mass spectrometry for fast reaction kinetics. Proc Natl Acad Sci U S A (2015) 0.80
Coalescing drops in microfluidic parking networks: A multifunctional platform for drop-based microfluidics. Biomicrofluidics (2014) 0.80
Exploring the new world of the genome with DNA microarrays. Nat Genet (1999) 19.05
The origins and the future of microfluidics. Nature (2006) 16.24
Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane). Anal Chem (1998) 15.53
Fabrication of microfluidic systems in poly(dimethylsiloxane). Electrophoresis (2000) 9.45
Cells on chips. Nature (2006) 8.40
Chaotic mixer for microchannels. Science (2002) 8.22
Microfluidic large-scale integration. Science (2002) 7.64
Poly(dimethylsiloxane) as a material for fabricating microfluidic devices. Acc Chem Res (2002) 7.35
Lab-on-a-chip: microfluidics in drug discovery. Nat Rev Drug Discov (2006) 5.65
An integrated nanoliter DNA analysis device. Science (1998) 5.40
Dynamic pattern formation in a vesicle-generating microfluidic device. Phys Rev Lett (2001) 4.27
A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion. Proc Natl Acad Sci U S A (2002) 4.16
Screening of protein crystallization conditions on a microfluidic chip using nanoliter-size droplets. J Am Chem Soc (2003) 3.97
Liquid marbles. Nature (2001) 3.86
A vesicle bioreactor as a step toward an artificial cell assembly. Proc Natl Acad Sci U S A (2004) 3.69
Controlled microfluidic interfaces. Nature (2005) 3.60
Long-term monitoring of bacteria undergoing programmed population control in a microchemostat. Science (2005) 3.54
Formation of droplets and bubbles in a microfluidic T-junction-scaling and mechanism of break-up. Lab Chip (2006) 3.17
Millisecond kinetics on a microfluidic chip using nanoliters of reagents. J Am Chem Soc (2003) 3.17
Selective encapsulation of single cells and subcellular organelles into picoliter- and femtoliter-volume droplets. Anal Chem (2005) 3.16
Monodisperse double emulsions generated from a microcapillary device. Science (2005) 3.11
Control and detection of chemical reactions in microfluidic systems. Nature (2006) 3.09
Colloidosomes: selectively permeable capsules composed of colloidal particles. Science (2002) 3.09
Partial liquid ventilation with perflubron in premature infants with severe respiratory distress syndrome. The LiquiVent Study Group. N Engl J Med (1996) 3.06
Microfabrication inside capillaries using multiphase laminar flow patterning Science (1999) 2.87
Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics. Science (2005) 2.83
The "One-Bead-One-Compound" Combinatorial Library Method. Chem Rev (1997) 2.82
Geometrically mediated breakup of drops in microfluidic devices. Phys Rev Lett (2004) 2.71
Integrated nanoliter systems. Nat Biotechnol (2003) 2.68
High-throughput protein crystallization. Curr Opin Struct Biol (2000) 2.50
Electrowetting-based actuation of droplets for integrated microfluidics. Lab Chip (2002) 2.47
Complex synthetic chemical libraries indexed with molecular tags. Proc Natl Acad Sci U S A (1993) 2.44
A droplet-based, composite PDMS/glass capillary microfluidic system for evaluating protein crystallization conditions by microbatch and vapor-diffusion methods with on-chip X-ray diffraction. Angew Chem Int Ed Engl (2004) 2.26
Micro/nano encapsulation via electrified coaxial liquid jets. Science (2002) 2.24
Controlling nonspecific protein adsorption in a plug-based microfluidic system by controlling interfacial chemistry using fluorous-phase surfactants. Anal Chem (2005) 2.15
Vibration-actuated drop motion on surfaces for batch microfluidic processes. Langmuir (2005) 2.14
Planar chip device for PCR and hybridization with surface acoustic wave pump. Lab Chip (2004) 2.02
Injectable microbubbles as contrast agents for diagnostic ultrasound imaging: the key role of perfluorochemicals. Angew Chem Int Ed Engl (2003) 2.01
Health risks in infants associated with exposure to perfluorinated compounds in human breast milk from Zhoushan, China. Environ Sci Technol (2006) 1.98
Chemical transformations in individual ultrasmall biomimetic containers. Science (1999) 1.93
Systematic investigation of protein phase behavior with a microfluidic formulator. Proc Natl Acad Sci U S A (2004) 1.88
Multi-step synthesis of nanoparticles performed on millisecond time scale in a microfluidic droplet-based system. Lab Chip (2004) 1.87
Design of microfluidic channel geometries for the control of droplet volume, chemical concentration, and sorting. Lab Chip (2004) 1.85
Parallel picoliter rt-PCR assays using microfluidics. Anal Chem (2006) 1.84
Microgram-scale testing of reaction conditions in solution using nanoliter plugs in microfluidics with detection by MALDI-MS. J Am Chem Soc (2006) 1.81
Permeation-driven flow in poly(dimethylsiloxane) microfluidic devices. Proc Natl Acad Sci U S A (2005) 1.77
A microfluidic approach for screening submicroliter volumes against multiple reagents by using preformed arrays of nanoliter plugs in a three-phase liquid/liquid/gas flow. Angew Chem Int Ed Engl (2005) 1.74
On-chip manipulation of free droplets. Nature (2003) 1.71
Protein microarray technology. Trends Biotechnol (2002) 1.68
Janus and ternary particles generated by microfluidic synthesis: design, synthesis, and self-assembly. J Am Chem Soc (2006) 1.67
A microfluidic device for kinetic optimization of protein crystallization and in situ structure determination. J Am Chem Soc (2006) 1.65
Surface-directed liquid flow inside microchannels. Science (2001) 1.64
Transport and reaction in microscale segmented gas-liquid flow. Lab Chip (2004) 1.64
Controlled production of monodisperse double emulsions by two-step droplet breakup in microfluidic devices. Langmuir (2004) 1.63
High-speed microfluidic differential manometer for cellular-scale hydrodynamics. Proc Natl Acad Sci U S A (2006) 1.63
Microfluidic systems for chemical kinetics that rely on chaotic mixing in droplets. Philos Trans A Math Phys Eng Sci (2004) 1.62
Applied physics. Designing optimal micromixers. Science (2004) 1.62
Using nanoliter plugs in microfluidics to facilitate and understand protein crystallization. Curr Opin Struct Biol (2005) 1.61
Experimental test of scaling of mixing by chaotic advection in droplets moving through microfluidic channels. Appl Phys Lett (2003) 1.57
Microfluidic and optical systems for the on-demand generation and manipulation of single femtoliter-volume aqueous droplets. Anal Chem (2006) 1.55
High-throughput screens and selections of enzyme-encoding genes. Curr Opin Chem Biol (2005) 1.54
Controlled microfluidic encapsulation of cells, proteins, and microbeads in lipid vesicles. J Am Chem Soc (2006) 1.54
Formation of droplets of alternating composition in microfluidic channels and applications to indexing of concentrations in droplet-based assays. Anal Chem (2004) 1.54
Applied physics. Droplet control for microfluidics. Science (2005) 1.53
Reagent-loaded cartridges for valveless and automated fluid delivery in microfluidic devices. Anal Chem (2005) 1.50
Dynamic microcompartmentation in synthetic cells. Proc Natl Acad Sci U S A (2005) 1.49
Perfectly monodisperse microbubbling by capillary flow focusing. Phys Rev Lett (2001) 1.49
Alternating droplet generation and controlled dynamic droplet fusion in microfluidic device for CdS nanoparticle synthesis. Lab Chip (2006) 1.49
Concentrating solutes and nanoparticles within individual aqueous microdroplets. Anal Chem (2004) 1.48
Encoding microcarriers: present and future technologies. Nat Rev Drug Discov (2002) 1.48
Droplet fusion by alternating current (AC) field electrocoalescence in microchannels. Electrophoresis (2005) 1.47
Linkers and cleavage strategies in solid-phase organic synthesis and combinatorial chemistry. Chem Rev (2000) 1.45
Droplet formation in a microchannel network. Lab Chip (2002) 1.44
Colloid science: non-spherical bubbles. Nature (2005) 1.44
Controlled synthesis of nonspherical microparticles using microfluidics. Langmuir (2005) 1.44
In situ data collection and structure refinement from microcapillary protein crystallization. J Appl Crystallogr (2005) 1.42
On-chip titration of an anticoagulant argatroban and determination of the clotting time within whole blood or plasma using a plug-based microfluidic system. Anal Chem (2006) 1.42
A microfluidic device for conducting gas-liquid-solid hydrogenation reactions. Science (2004) 1.41
Microfluidic flow focusing: drop size and scaling in pressure versus flow-rate-driven pumping. Electrophoresis (2005) 1.38
The intensification of rapid reactions in multiphase systems using slug flow in capillaries. Lab Chip (2001) 1.36
Micromixing of miscible liquids in segmented gas-liquid flow. Langmuir (2005) 1.36
High-temperature microfluidic synthesis of CdSe nanocrystals in nanoliter droplets. J Am Chem Soc (2005) 1.35
Mixing with bubbles: a practical technology for use with portable microfluidic devices. Lab Chip (2005) 1.31
Using microfluidics to observe the effect of mixing on nucleation of protein crystals. J Am Chem Soc (2005) 1.31
Polymer particles with various shapes and morphologies produced in continuous microfluidic reactors. J Am Chem Soc (2005) 1.31
Formation of Arrayed Droplets by Soft Lithography and Two-Phase Fluid Flow, and Application in Protein Crystallization. Adv Mater (2004) 1.30
Production of arrays of chemically distinct nanolitre plugs via repeated splitting in microfluidic devices. Lab Chip (2006) 1.30
Generation of larger numbers of separated microbial populations by cultivation in segmented-flow microdevices. Lab Chip (2003) 1.29
MULTIPLE AUTOMATIC SEQUENTIAL ANALYSIS. Clin Chem (1964) 1.26
Microfluidic synthesis of colloidal silica. Langmuir (2004) 1.23
High-throughput microcoil NMR of compound libraries using zero-dispersion segmented flow analysis. J Comb Chem (2005) 1.22
Digital microfluidics with in-line sample purification for proteomics analyses with MALDI-MS. Anal Chem (2005) 1.22
Microfluidic production of biopolymer microcapsules with controlled morphology. J Am Chem Soc (2006) 1.20
In vitro compartmentalization by double emulsions: sorting and gene enrichment by fluorescence activated cell sorting. Anal Biochem (2004) 1.20
The application of micro reactors for organic synthesis. Chem Soc Rev (2005) 1.16
A new embedded process for compartmentalized cell-free protein expression and on-line detection in microfluidic devices. Chembiochem (2005) 1.15
Fluorinated materials for in vivo oxygen transport (blood substitutes), diagnosis and drug delivery. Biomaterials (1998) 1.14
Chemical reactions in microdroplets by electrostatic manipulation of droplets in liquid media. Lab Chip (2002) 1.14
Continuous segmented-flow polymerase chain reaction for high-throughput miniaturized DNA amplification. Anal Chem (2003) 1.11
Droplet traffic at a simple junction at low capillary numbers. Phys Rev Lett (2005) 1.11
Screening of protein crystallization conditions on a microfluidic chip using nanoliter-size droplets. J Am Chem Soc (2003) 3.97
A microfluidic system for controlling reaction networks in time. Angew Chem Int Ed Engl (2003) 3.96
Millisecond kinetics on a microfluidic chip using nanoliters of reagents. J Am Chem Soc (2003) 3.17
Dynamics of Drosophila embryonic patterning network perturbed in space and time using microfluidics. Nature (2005) 3.01
Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins. Proc Natl Acad Sci U S A (2006) 2.66
Defined spatial structure stabilizes a synthetic multispecies bacterial community. Proc Natl Acad Sci U S A (2008) 2.42
A droplet-based, composite PDMS/glass capillary microfluidic system for evaluating protein crystallization conditions by microbatch and vapor-diffusion methods with on-chip X-ray diffraction. Angew Chem Int Ed Engl (2004) 2.26
Controlling nonspecific protein adsorption in a plug-based microfluidic system by controlling interfacial chemistry using fluorous-phase surfactants. Anal Chem (2005) 2.15
Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidics. Lab Chip (2008) 2.11
Microfluidic confinement of single cells of bacteria in small volumes initiates high-density behavior of quorum sensing and growth and reveals its variability. Angew Chem Int Ed Engl (2009) 1.99
The chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution. Proc Natl Acad Sci U S A (2008) 1.90
Multi-step synthesis of nanoparticles performed on millisecond time scale in a microfluidic droplet-based system. Lab Chip (2004) 1.87
SlipChip. Lab Chip (2009) 1.84
Microgram-scale testing of reaction conditions in solution using nanoliter plugs in microfluidics with detection by MALDI-MS. J Am Chem Soc (2006) 1.81
A microfluidic approach for screening submicroliter volumes against multiple reagents by using preformed arrays of nanoliter plugs in a three-phase liquid/liquid/gas flow. Angew Chem Int Ed Engl (2005) 1.74
Spatial localization of bacteria controls coagulation of human blood by 'quorum acting'. Nat Chem Biol (2008) 1.74
Microfluidic systems for chemical kinetics that rely on chaotic mixing in droplets. Philos Trans A Math Phys Eng Sci (2004) 1.62
Using nanoliter plugs in microfluidics to facilitate and understand protein crystallization. Curr Opin Struct Biol (2005) 1.61
Experimental test of scaling of mixing by chaotic advection in droplets moving through microfluidic channels. Appl Phys Lett (2003) 1.57
Digital PCR on a SlipChip. Lab Chip (2010) 1.57
Formation of droplets of alternating composition in microfluidic channels and applications to indexing of concentrations in droplet-based assays. Anal Chem (2004) 1.54
Multiplexed quantification of nucleic acids with large dynamic range using multivolume digital RT-PCR on a rotational SlipChip tested with HIV and hepatitis C viral load. J Am Chem Soc (2011) 1.51
Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization. Angew Chem Int Ed Engl (2006) 1.45
In situ data collection and structure refinement from microcapillary protein crystallization. J Appl Crystallogr (2005) 1.42
On-chip titration of an anticoagulant argatroban and determination of the clotting time within whole blood or plasma using a plug-based microfluidic system. Anal Chem (2006) 1.42
Modular chemical mechanism predicts spatiotemporal dynamics of initiation in the complex network of hemostasis. Proc Natl Acad Sci U S A (2006) 1.36
Digital isothermal quantification of nucleic acids via simultaneous chemical initiation of recombinase polymerase amplification reactions on SlipChip. Anal Chem (2011) 1.36
Threshold response of initiation of blood coagulation by tissue factor in patterned microfluidic capillaries is controlled by shear rate. Arterioscler Thromb Vasc Biol (2008) 1.33
Theoretical design and analysis of multivolume digital assays with wide dynamic range validated experimentally with microfluidic digital PCR. Anal Chem (2011) 1.32
Using microfluidics to observe the effect of mixing on nucleation of protein crystals. J Am Chem Soc (2005) 1.31
Nanoliter multiplex PCR arrays on a SlipChip. Anal Chem (2010) 1.30
Formation of Arrayed Droplets by Soft Lithography and Two-Phase Fluid Flow, and Application in Protein Crystallization. Adv Mater (2004) 1.30
Production of arrays of chemically distinct nanolitre plugs via repeated splitting in microfluidic devices. Lab Chip (2006) 1.30
Protein crystallization using microfluidic technologies based on valves, droplets, and SlipChip. Annu Rev Biophys (2010) 1.28
Microfluidic cartridges preloaded with nanoliter plugs of reagents: an alternative to 96-well plates for screening. Curr Opin Chem Biol (2006) 1.28
Using a multijunction microfluidic device to inject substrate into an array of preformed plugs without cross-contamination: comparing theory and experiments. Anal Chem (2007) 1.20
Effects of shear rate on propagation of blood clotting determined using microfluidics and numerical simulations. J Am Chem Soc (2008) 1.19
A precise Bicoid gradient is nonessential during cycles 11-13 for precise patterning in the Drosophila blastoderm. PLoS One (2008) 1.15
Characterization of the threshold response of initiation of blood clotting to stimulus patch size. Biophys J (2007) 1.15
Minimal functional model of hemostasis in a biomimetic microfluidic system. Angew Chem Int Ed Engl (2004) 1.13
SlipChip for immunoassays in nanoliter volumes. Anal Chem (2010) 1.13
Rate of mixing controls rate and outcome of autocatalytic processes: theory and microfluidic experiments with chemical reactions and blood coagulation. Biophys J (2008) 1.11
Characterization of the local temperature in space and time around a developing Drosophila embryo in a microfluidic device. Lab Chip (2006) 1.11
Multiparameter screening on SlipChip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods. J Am Chem Soc (2010) 1.10
Microfluidic stochastic confinement enhances analysis of rare cells by isolating cells and creating high density environments for control of diffusible signals. Chem Soc Rev (2010) 1.10
Using three-phase flow of immiscible liquids to prevent coalescence of droplets in microfluidic channels: criteria to identify the third liquid and validation with protein crystallization. Langmuir (2007) 1.08
Evolution of catalysts directed by genetic algorithms in a plug-based microfluidic device tested with oxidation of methane by oxygen. J Am Chem Soc (2010) 1.07
A synthetic reaction network: chemical amplification using nonequilibrium autocatalytic reactions coupled in time. J Am Chem Soc (2004) 1.07
Chemical stimulation of the Arabidopsis thaliana root using multi-laminar flow on a microfluidic chip. Lab Chip (2010) 1.04
Microfluidics using spatially defined arrays of droplets in one, two, and three dimensions. Annu Rev Anal Chem (Palo Alto Calif) (2011) 1.03
Laterally mobile, functionalized self-assembled monolayers at the fluorous-aqueous interface in a plug-based microfluidic system: characterization and testing with membrane protein crystallization. J Am Chem Soc (2009) 1.02
Combining microfluidic networks and peptide arrays for multi-enzyme assays. J Am Chem Soc (2005) 1.00
Mechanistic evaluation of the pros and cons of digital RT-LAMP for HIV-1 viral load quantification on a microfluidic device and improved efficiency via a two-step digital protocol. Anal Chem (2013) 0.99
Plug-based microfluidics with defined surface chemistry to miniaturize and control aggregation of amyloidogenic peptides. Angew Chem Int Ed Engl (2009) 0.97
Propagation of blood clotting in the complex biochemical network of hemostasis is described by a simple mechanism. J Am Chem Soc (2007) 0.95
Increased robustness of single-molecule counting with microfluidics, digital isothermal amplification, and a mobile phone versus real-time kinetic measurements. Anal Chem (2013) 0.94
Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain. J Mol Biol (2010) 0.94
Dynamics of coalescence of plugs with a hydrophilic wetting layer induced by flow in a microfluidic chemistrode. Langmuir (2009) 0.94
A Plug-Based Microfluidic System for Dispensing Lipidic Cubic Phase (LCP) Material Validated by Crystallizing Membrane Proteins in Lipidic Mesophases. Microfluid Nanofluidics (2010) 0.93
Dead-end filling of SlipChip evaluated theoretically and experimentally as a function of the surface chemistry and the gap size between the plates for lubricated and dry SlipChips. Langmuir (2010) 0.91
Simple host-guest chemistry to modulate the process of concentration and crystallization of membrane proteins by detergent capture in a microfluidic device. J Am Chem Soc (2008) 0.90
The pumping lid: investigating multi-material 3D printing for equipment-free, programmable generation of positive and negative pressures for microfluidic applications. Lab Chip (2014) 0.90
Complex function by design using spatially pre-structured synthetic microbial communities: degradation of pentachlorophenol in the presence of Hg(ii). Integr Biol (Camb) (2010) 0.90
A genetically encoded and gate for cell-targeted metabolic labeling of proteins. J Am Chem Soc (2013) 0.88
Digital biology and chemistry. Lab Chip (2014) 0.87
ABO, D blood typing and subtyping using plug-based microfluidics. Anal Chem (2008) 0.87
Using chemistry and microfluidics to understand the spatial dynamics of complex biological networks. Acc Chem Res (2008) 0.85
The endo-siRNA pathway is essential for robust development of the Drosophila embryo. PLoS One (2009) 0.85
Individually addressable arrays of replica microbial cultures enabled by splitting SlipChips. Integr Biol (Camb) (2014) 0.85
Response to shape emerges in a complex biochemical network and its simple chemical analogue. Angew Chem Int Ed Engl (2007) 0.84
Using microfluidics to understand the effect of spatial distribution of tissue factor on blood coagulation. Thromb Res (2008) 0.82
A microfluidic device for dry sample preservation in remote settings. Lab Chip (2013) 0.82
Confinement regulates complex biochemical networks: initiation of blood clotting by "diffusion acting". Biophys J (2009) 0.81
Digital, ultrasensitive, end-point protein measurements with large dynamic range via Brownian trapping with drift. J Am Chem Soc (2014) 0.79
Three-dimensional nanocrystal superlattices grown in nanoliter microfluidic plugs. J Am Chem Soc (2011) 0.79
Evaluating 3D printing to solve the sample-to-device interface for LRS and POC diagnostics: example of an interlock meter-mix device for metering and lysing clinical urine samples. Lab Chip (2016) 0.78
Control of initiation, rate, and routing of spontaneous capillary-driven flow of liquid droplets through microfluidic channels on SlipChip. Langmuir (2012) 0.78
Using TIRF microscopy to quantify and confirm efficient mass transfer at the substrate surface of the chemistrode. New J Phys (2009) 0.78
Toward mechanistic understanding of nuclear reprocessing chemistries by quantifying lanthanide solvent extraction kinetics via microfluidics with constant interfacial area and rapid mixing. J Am Chem Soc (2011) 0.78
Chemical analog-to-digital signal conversion based on robust threshold chemistry and its evaluation in the context of microfluidics-based quantitative assays. J Am Chem Soc (2013) 0.77
Structural and spectropotentiometric analysis of Blastochloris viridis heterodimer mutant reaction center. Biochim Biophys Acta (2009) 0.76
Corrigendum: Digital Quantification of DNA Replication and Chromosome Segregation Enables Determination of Antimicrobial Susceptibility after only 15 Minutes of Antibiotic Exposure. Angew Chem Int Ed Engl (2017) 0.75