Published in J Biol Chem on November 06, 2006
Function, structure and therapeutic potential of complement C5a receptors. Br J Pharmacol (2007) 2.25
Structural and kinetic modeling of an activating helix switch in the rhodopsin-transducin interface. Proc Natl Acad Sci U S A (2009) 1.03
Role of the carboxyl terminal di-leucine in phosphorylation and internalization of C5a receptor. Biochim Biophys Acta (2008) 0.83
Simplified modeling approach suggests structural mechanisms for constitutive activation of the C5a receptor. Proteins (2010) 0.79
Essential role for the second extracellular loop in C5a receptor activation. Nat Struct Mol Biol (2005) 2.71
A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila. Dis Model Mech (2011) 1.92
Transformed Drosophila cells evade diet-mediated insulin resistance through wingless signaling. Cell (2013) 1.69
C5a receptor oligomerization. I. Disulfide trapping reveals oligomers and potential contact surfaces in a G protein-coupled receptor. J Biol Chem (2003) 1.44
Synthesis and characterization of a macrocyclic near-infrared optical scaffold. J Am Chem Soc (2003) 1.33
A Drosophila model of high sugar diet-induced cardiomyopathy. PLoS Genet (2013) 1.28
Modeling the possible conformations of the extracellular loops in G-protein-coupled receptors. Proteins (2010) 1.27
Genetic analysis of the first and third extracellular loops of the C5a receptor reveals an essential WXFG motif in the first loop. J Biol Chem (2006) 1.00
Evidence for transgenerational metabolic programming in Drosophila. Dis Model Mech (2013) 0.98
C5a receptor oligomerization. II. Fluorescence resonance energy transfer studies of a human G protein-coupled receptor expressed in yeast. J Biol Chem (2003) 0.98
Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor. Traffic (2002) 0.98
Prognostic factors in patients with well-differentiated thyroid cancer presenting with pulmonary metastasis. Cancer Biother Radiopharm (2008) 0.95
Role of fat body lipogenesis in protection against the effects of caloric overload in Drosophila. J Biol Chem (2013) 0.93
Constitutive activity of neural melanocortin receptors. Methods Enzymol (2010) 0.92
Electron paramagnetic resonance studies of functionally active, nitroxide spin-labeled peptide analogues of the C-terminus of a G-protein alpha subunit. Biochemistry (2010) 0.91
Structure of the complement factor 5a receptor-ligand complex studied by disulfide trapping and molecular modeling. J Biol Chem (2008) 0.91
Modeling molecular mechanisms of binding of the anaphylatoxin C5a to the C5a receptor. Biochemistry (2008) 0.89
Beta2-chimaerin in cancer signaling: connecting cell adhesion and MAP kinase activation. Cell Cycle (2007) 0.89
Exploring new near-infrared fluorescent disulfide-based cyclic RGD peptide analogs for potential integrin-targeted optical imaging. Bioorg Med Chem Lett (2011) 0.88
Third extracellular loop (EC3)-N terminus interaction is important for seven-transmembrane domain receptor function: implications for an activation microswitch region. J Biol Chem (2010) 0.87
Targeting Beta-3 integrin using a linear hexapeptide labeled with a near-infrared fluorescent molecular probe. Mol Pharm (2006) 0.86
Chimaerin and Rac regulate cell number, adherens junctions, and ERK MAP kinase signaling in the Drosophila eye. Proc Natl Acad Sci U S A (2007) 0.85
Insight into the binding mode for cyclopentapeptide antagonists of the CXCR4 receptor. Chem Biol Drug Des (2006) 0.85
Motion of carboxyl terminus of Galpha is restricted upon G protein activation. A solution NMR study using semisynthetic Galpha subunits. J Biol Chem (2005) 0.84
Frizzled receptors signal through G proteins. Cell Signal (2013) 0.82
Structural mechanisms of constitutive activation in the C5a receptors with mutations in the extracellular loops: molecular modeling study. Proteins (2011) 0.82
A comprehensive structure-function map of the intracellular surface of the human C5a receptor. I. Identification of critical residues. J Biol Chem (2006) 0.81
Random mutagenesis of the complement factor 5a (C5a) receptor N terminus provides a structural constraint for C5a docking. J Biol Chem (2006) 0.80
Difference between restoring and predicting 3D structures of the loops in G-protein-coupled receptors by molecular modeling. Proc Natl Acad Sci U S A (2011) 0.80
A Drosophila functional evaluation of candidates from human genome-wide association studies of type 2 diabetes and related metabolic traits identifies tissue-specific roles for dHHEX. BMC Genomics (2013) 0.80
Expressed protein ligation to study protein interactions: semi-synthesis of the G-protein alpha subunit. Protein Pept Lett (2005) 0.80
Conformational templates for rational drug design: flexibility of cyclo(D-Pro1-Ala2-Ala3-Ala4-Ala5) in DMSO solution. J Med Chem (2007) 0.79
Simplified modeling approach suggests structural mechanisms for constitutive activation of the C5a receptor. Proteins (2010) 0.79
Structural models for the complex of chemotaxis inhibitory protein of Staphylococcus aureus with the C5a receptor. Biochem Biophys Res Commun (2009) 0.78
Defining the interface between the C-terminal fragment of alpha-transducin and photoactivated rhodopsin. Biophys J (2007) 0.77
Conformational movement of F251 contributes to the molecular mechanism of constitutive activation in the C5a receptor. Chem Biol Drug Des (2008) 0.77
E2F8 is a nonreceptor activator of heterotrimeric G proteins. J Mol Signal (2007) 0.77
Vinyl sulfide cyclized analogues of angiotensin II with high affinity and full agonist activity at the AT(1) receptor. J Med Chem (2002) 0.77
Complement factor 5a receptor chimeras reveal the importance of lipid-facing residues in transport competence. FEBS J (2009) 0.77
Thyroid cancer: what to do after fine needle aspiration. Mo Med (2011) 0.76
Comparison of the retinitis pigmentosa mutations in rhodopsin with a functional map of the C5a receptor. Vision Res (2006) 0.76
A minimalistic 3D pharmacophore model for cyclopentapeptide CXCR4 antagonists. Biopolymers (2006) 0.76
Computational modeling of constitutively active mutants of GPCRs C5a receptor. Methods Enzymol (2010) 0.75