Published in J Biol Chem on November 13, 2006
Stoichiometry and architecture of active DNA replication machinery in Escherichia coli. Science (2010) 2.58
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis. Nature (2008) 2.09
Single-molecule analysis reveals that the lagging strand increases replisome processivity but slows replication fork progression. Proc Natl Acad Sci U S A (2009) 1.30
Single-molecule studies reveal the function of a third polymerase in the replisome. Nat Struct Mol Biol (2011) 1.26
Dynamic coupling between the motors of DNA replication: hexameric helicase, DNA polymerase, and primase. Curr Opin Chem Biol (2011) 1.24
Coordinating DNA polymerase traffic during high and low fidelity synthesis. Biochim Biophys Acta (2009) 1.20
Replisome structure and conformational dynamics underlie fork progression past obstacles. Curr Opin Cell Biol (2009) 0.99
Timing, coordination, and rhythm: acrobatics at the DNA replication fork. J Biol Chem (2010) 0.98
New insights into replisome fluidity during chromosome replication. Trends Biochem Sci (2012) 0.98
Replisome dynamics and use of DNA trombone loops to bypass replication blocks. Mol Biosyst (2008) 0.95
Investigation of stoichiometry of T4 bacteriophage helicase loader protein (gp59). J Biol Chem (2009) 0.93
Response of the bacteriophage T4 replisome to noncoding lesions and regression of a stalled replication fork. J Mol Biol (2010) 0.91
Single-molecule analysis of the Escherichia coli replisome and use of clamps to bypass replication barriers. FEBS Lett (2010) 0.91
Discrete interactions between bacteriophage T7 primase-helicase and DNA polymerase drive the formation of a priming complex containing two copies of DNA polymerase. Biochemistry (2013) 0.80
Experimental approaches for addressing fundamental biological questions in living, functioning cells with single molecule precision. Open Biol (2012) 0.80
Stability versus exchange: a paradox in DNA replication. Nucleic Acids Res (2016) 0.80
Models for the binary complex of bacteriophage T4 gp59 helicase loading protein: gp32 single-stranded DNA-BINDING protein and ternary complex with pseudo-Y junction DNA. J Biol Chem (2012) 0.80
Insights into Okazaki fragment synthesis by the T4 replisome: the fate of lagging-strand holoenzyme components and their influence on Okazaki fragment size. J Biol Chem (2013) 0.78
Coordinated DNA Replication by the Bacteriophage T4 Replisome. Viruses (2015) 0.78
Many ways to loop DNA. J Biol Chem (2013) 0.78
Evolution of replication machines. Crit Rev Biochem Mol Biol (2015) 0.78
Single-molecule FRET studies of the cooperative and non-cooperative binding kinetics of the bacteriophage T4 single-stranded DNA binding protein (gp32) to ssDNA lattices at replication fork junctions. Nucleic Acids Res (2016) 0.77
Replisome mechanics: lagging strand events that influence speed and processivity. Nucleic Acids Res (2014) 0.77
Mutational analysis of the T4 gp59 helicase loader reveals its sites for interaction with helicase, single-stranded binding protein, and DNA. J Biol Chem (2012) 0.77
Free-energy calculations for semi-flexible macromolecules: applications to DNA knotting and looping. J Chem Phys (2014) 0.76
Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome. Structure (2017) 0.76
DNA replication catalyzed by herpes simplex virus type 1 proteins reveals trombone loops at the fork. J Biol Chem (2014) 0.75
What maintains the high intra-follicular estradiol concentration in pre-ovulatory follicles? J Assist Reprod Genet (2015) 0.75
The UL8 subunit of the helicase/primase complex of herpes simplex virus promotes DNA annealing and has a high affinity for replication forks. J Biol Chem (2017) 0.75
Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. Cell (2009) 5.56
Mechanism of replication-coupled DNA interstrand crosslink repair. Cell (2008) 4.53
Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis. Cell (2012) 2.98
Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs. Nucleic Acids Res (2007) 2.95
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro. Proc Natl Acad Sci U S A (2003) 2.80
Synapsis of DNA ends by DNA-dependent protein kinase. EMBO J (2002) 2.62
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Mol Cell Biol (2007) 2.54
Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodia. Cell (2008) 2.28
Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops. Mol Cell Biol (2004) 2.23
Termination factor-mediated DNA loop between termination and initiation sites drives mitochondrial rRNA synthesis. Cell (2005) 2.01
Preferential binding of ATR protein to UV-damaged DNA. Proc Natl Acad Sci U S A (2002) 1.87
The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA. Nat Struct Mol Biol (2010) 1.85
C. elegans telomeres contain G-strand and C-strand overhangs that are bound by distinct proteins. Cell (2008) 1.65
F-actin binding is essential for coronin 1B function in vivo. J Cell Sci (2007) 1.55
Mechanism of Holliday junction resolution by the human GEN1 protein. Genes Dev (2010) 1.54
Unpacking a gel-forming mucin: a view of MUC5B organization after granular release. Am J Physiol Lung Cell Mol Physiol (2009) 1.52
The enterovirus 71 A-particle forms a gateway to allow genome release: a cryoEM study of picornavirus uncoating. PLoS Pathog (2013) 1.52
Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid. J Mol Biol (2010) 1.50
Human CST promotes telomere duplex replication and general replication restart after fork stalling. EMBO J (2012) 1.47
The basic domain of TRF2 directs binding to DNA junctions irrespective of the presence of TTAGGG repeats. J Biol Chem (2006) 1.45
Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development. Mol Cell Biol (2008) 1.36
Catalysis of strand exchange by the HSV-1 UL12 and ICP8 proteins: potent ICP8 recombinase activity is revealed upon resection of dsDNA substrate by nuclease. J Mol Biol (2004) 1.35
Replication fork regression in repetitive DNAs. Nucleic Acids Res (2006) 1.35
Telomere looping in P. sativum (common garden pea). Plant J (2003) 1.32
Structures of the procapsid and mature virion of enterovirus 71 strain 1095. J Virol (2013) 1.32
5-Azacytidine induced methyltransferase-DNA adducts block DNA replication in vivo. Cancer Res (2007) 1.31
Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells. Cancer Res (2007) 1.27
Lagging strand synthesis in coordinated DNA synthesis by bacteriophage t7 replication proteins. J Mol Biol (2002) 1.24
The processing of Holliday junctions by BLM and WRN helicases is regulated by p53. J Biol Chem (2002) 1.22
Crystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how flap endonuclease-1 family nucleases bind their substrates. J Biol Chem (2007) 1.21
Regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic Acid by GTP. J Biol Chem (2005) 1.21
The carboxyl-terminal domain of bacteriophage T7 single-stranded DNA-binding protein modulates DNA binding and interaction with T7 DNA polymerase. J Biol Chem (2003) 1.21
Telomere loops and homologous recombination-dependent telomeric circles in a Kluyveromyces lactis telomere mutant strain. Mol Cell Biol (2007) 1.20
Architecture of the replication complex and DNA loops at the fork generated by the bacteriophage t4 proteins. J Biol Chem (2003) 1.19
Hairpin formation in Friedreich's ataxia triplet repeat expansion. J Biol Chem (2002) 1.19
The Werner syndrome protein binds replication fork and holliday junction DNAs as an oligomer. J Biol Chem (2008) 1.18
Role of p38 in replication of Trypanosoma brucei kinetoplast DNA. Mol Cell Biol (2006) 1.15
Modulation of B-cell exosome proteins by gamma herpesvirus infection. Proc Natl Acad Sci U S A (2013) 1.14
Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures. J Biol Chem (2004) 1.13
The killing of African trypanosomes by ethidium bromide. PLoS Pathog (2010) 1.12
Origin-specific unwinding of herpes simplex virus 1 DNA by the viral UL9 and ICP8 proteins: visualization of a specific preunwinding complex. Proc Natl Acad Sci U S A (2003) 1.11
Extrachromosomal microDNAs and chromosomal microdeletions in normal tissues. Science (2012) 1.11
Taz1 binding to a fission yeast model telomere: formation of telomeric loops and higher order structures. J Biol Chem (2004) 1.11
Telomeric circles: universal players in telomere maintenance? Nat Struct Mol Biol (2009) 1.10
Human heart mitochondrial DNA is organized in complex catenated networks containing abundant four-way junctions and replication forks. J Biol Chem (2009) 1.09
Chaperone proteins abrogate inhibition of the human papillomavirus (HPV) E1 replicative helicase by the HPV E2 protein. Mol Cell Biol (2002) 1.07
E. coli DNA replication in the absence of free β clamps. EMBO J (2011) 1.04
Differential single-stranded DNA binding properties of the paralogous SsbA and SsbB proteins from Streptococcus pneumoniae. J Biol Chem (2005) 1.04
Recombination at long mutant telomeres produces tiny single- and double-stranded telomeric circles. Mol Cell Biol (2005) 1.03
p53 Monitors replication fork regression by binding to "chickenfoot" intermediates. J Biol Chem (2005) 1.02
BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression. Nucleic Acids Res (2010) 1.02
Amplification of telomeric arrays via rolling-circle mechanism. J Biol Chem (2005) 1.02
Sticky DNA, a long GAA.GAA.TTC triplex that is formed intramolecularly, in the sequence of intron 1 of the frataxin gene. J Biol Chem (2002) 1.01
A strain-specific epitope of enterovirus 71 identified by cryo-electron microscopy of the complex with fab from neutralizing antibody. J Virol (2013) 0.99
The NAD(+)-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric status. Sci Rep (2012) 0.98
Human Rap1 interacts directly with telomeric DNA and regulates TRF2 localization at the telomere. J Biol Chem (2012) 0.98
Reconstitution of long and short patch mismatch repair reactions using Saccharomyces cerevisiae proteins. Proc Natl Acad Sci U S A (2013) 0.97
Ring-shaped Rad51 paralog protein complexes bind Holliday junctions and replication forks as visualized by electron microscopy. J Biol Chem (2010) 0.96
Nanoassembly of surfactants with interfacial drug-interactive motifs as tailor-designed drug carriers. Mol Pharm (2012) 0.96
An intramolecular salt bridge drives the soluble domain of GTP-bound atlastin into the postfusion conformation. J Cell Biol (2011) 0.95
Analysis of re-replication from deregulated origin licensing by DNA fiber spreading. Nucleic Acids Res (2008) 0.95
The bipolar filaments formed by herpes simplex virus type 1 SSB/recombination protein (ICP8) suggest a mechanism for DNA annealing. J Mol Biol (2008) 0.95
Kinetic and structural analysis of coxsackievirus B3 receptor interactions and formation of the A-particle. J Virol (2014) 0.94
Structure of long telomeric RNA transcripts: the G-rich RNA forms a compact repeating structure containing G-quartets. J Biol Chem (2009) 0.94
DNA replication in early S phase pauses near newly activated origins. Cell Cycle (2008) 0.94
Polymerization and nucleic acid-binding properties of human L1 ORF1 protein. Nucleic Acids Res (2011) 0.93
TbPIF1, a Trypanosoma brucei mitochondrial DNA helicase, is essential for kinetoplast minicircle replication. J Biol Chem (2009) 0.93
Open-channel structures of the human glycine receptor α1 full-length transmembrane domain. Structure (2013) 0.93
p53 binds telomeric single strand overhangs and t-loop junctions in vitro. J Biol Chem (2002) 0.92
Mapping subunit location on the Saccharomyces cerevisiae origin recognition complex free and bound to DNA using a novel nanoscale biopointer. J Biol Chem (2004) 0.92
The Cullin-RING E3 ubiquitin ligase CRL4-DCAF1 complex dimerizes via a short helical region in DCAF1. Biochemistry (2011) 0.91
Visualization of the annealing of complementary single-stranded DNA catalyzed by the herpes simplex virus type 1 ICP8 SSB/recombinase. J Mol Biol (2005) 0.91
t-Loops in yeast mitochondria. Mitochondrion (2002) 0.90
FEN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells. Mol Cancer Res (2010) 0.90
Two-dimensional crystallization of herpes simplex virus type 1 single-stranded DNA-binding protein, ICP8, on a lipid monolayer. Biochim Biophys Acta (2004) 0.88
Mapping of an origin of DNA replication in the promoter of fragile X gene FMR1. Exp Mol Pathol (2006) 0.88
Biophysical and ultrastructural characterization of adeno-associated virus capsid uncoating and genome release. J Virol (2012) 0.87
Synthesis and dissolution of hemicatenanes by type IA DNA topoisomerases. Proc Natl Acad Sci U S A (2013) 0.86
Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation. J Biol Chem (2008) 0.86
Disulfide bond formation contributes to herpes simplex virus capsid stability and retention of pentons. J Virol (2011) 0.85
Electron microscopic visualization of telomerase from Euplotes aediculatus bound to a model telomere DNA. Biochemistry (2006) 0.85
Interactions between p53, hMSH2-hMSH6 and HMG I(Y) on Holliday junctions and bulged bases. Nucleic Acids Res (2002) 0.85
A single-stranded DNA-binding protein of bacteriophage T7 defective in DNA annealing. J Biol Chem (2003) 0.85
DNA replication and the GINS complex: localization on extended chromatin fibers. Epigenetics Chromatin (2009) 0.84
The Epstein-Barr virus polymerase accessory factor BMRF1 adopts a ring-shaped structure as visualized by electron microscopy. J Biol Chem (2004) 0.83
Details of ssDNA annealing revealed by an HSV-1 ICP8-ssDNA binary complex. Nucleic Acids Res (2013) 0.83
Modulation of p53 binding to Holliday junctions and 3-cytosine bulges by phosphorylation events. Biochemistry (2005) 0.82
TRF1 and TRF2 differentially modulate Rad51-mediated telomeric and nontelomeric displacement loop formation in vitro. Biochemistry (2014) 0.81
Titanium dioxide nanoparticles activate the ATM-Chk2 DNA damage response in human dermal fibroblasts. Nanotoxicology (2012) 0.81
Synergism of the two Myb domains of Tay1 protein results in high affinity binding to telomeres. J Biol Chem (2012) 0.81
Early S phase DNA replication: a search for targets of carcinogenesis. Adv Enzyme Regul (2006) 0.81