Published in J Immunol on December 01, 2006
Genome-wide identification of post-translational modulators of transcription factor activity in human B cells. Nat Biotechnol (2009) 2.79
Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma. Blood (2007) 2.31
BRAF Mutants Evade ERK-Dependent Feedback by Different Mechanisms that Determine Their Sensitivity to Pharmacologic Inhibition. Cancer Cell (2015) 1.71
Regulation of innate immune response by MAP kinase phosphatase-1. Cell Signal (2007) 1.65
MAPK signaling in inflammation-associated cancer development. Protein Cell (2010) 1.23
TGF beta-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2. EMBO Rep (2008) 1.20
The immunobiology of cholangiocytes. Immunol Cell Biol (2008) 1.18
DUSPs, to MAP kinases and beyond. Cell Biosci (2012) 1.16
MAPK activation modulates permeability of isolated rat alveolar epithelial cell monolayers following cyclic stretch. PLoS One (2010) 1.15
TRPV1 activation is required for hypertonicity-stimulated inflammatory cytokine release in human corneal epithelial cells. Invest Ophthalmol Vis Sci (2011) 1.15
Acetylation of MKP-1 and the control of inflammation. Sci Signal (2008) 1.14
Prenatal arsenic exposure and the epigenome: altered microRNAs associated with innate and adaptive immune signaling in newborn cord blood. Environ Mol Mutagen (2013) 1.13
Transcriptional regulation of human dual specificity protein phosphatase 1 (DUSP1) gene by glucocorticoids. PLoS One (2010) 1.12
Toll-like receptor 4 and MYD88-dependent signaling mechanisms of the innate immune system are essential for the response to lipopolysaccharide by epithelial and stromal cells of the bovine endometrium. Biol Reprod (2012) 1.08
Mitogen-activated protein kinase phosphatase (MKP)-1 in immunology, physiology, and disease. Life Sci (2011) 1.08
Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages. J Biol Chem (2011) 1.07
Glucocorticoid regulation of mouse and human dual specificity phosphatase 1 (DUSP1) genes: unusual cis-acting elements and unexpected evolutionary divergence. J Biol Chem (2009) 1.05
Targeting mRNA stability arrests inflammatory bone loss. Mol Ther (2008) 1.04
Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice. PLoS One (2011) 1.03
A common neuronal response to alphaherpesvirus infection. J Neuroimmune Pharmacol (2010) 1.02
Staphylococcus aureus Biofilm and Planktonic cultures differentially impact gene expression, mapk phosphorylation, and cytokine production in human keratinocytes. BMC Microbiol (2011) 1.00
Suppression of dual-specificity phosphatase-2 by hypoxia increases chemoresistance and malignancy in human cancer cells. J Clin Invest (2011) 1.00
A non-redundant role for MKP5 in limiting ROS production and preventing LPS-induced vascular injury. EMBO J (2009) 0.99
Mitogen-activated protein kinase phosphatase 2 regulates the inflammatory response in sepsis. Infect Immun (2010) 0.98
Deletion of the dual specific phosphatase-4 (DUSP-4) gene reveals an essential non-redundant role for MAP kinase phosphatase-2 (MKP-2) in proliferation and cell survival. J Biol Chem (2011) 0.98
Increased inflammation and lethality of Dusp1-/- mice in polymicrobial peritonitis models. Immunology (2010) 0.98
Gene expression changes in mononuclear cells in patients with metabolic syndrome after acute intake of phenol-rich virgin olive oil. BMC Genomics (2010) 0.97
Overproduction, purification and structure determination of human dual-specificity phosphatase 14. Acta Crystallogr D Biol Crystallogr (2009) 0.97
IgE-induced mast cell survival requires the prolonged generation of reactive oxygen species. J Immunol (2008) 0.95
JNK pathway activation is controlled by Tao/TAOK3 to modulate ethanol sensitivity. PLoS One (2012) 0.92
Measurement of TLR-Induced Macrophage Spreading by Automated Image Analysis: Differential Role of Myd88 and MAPK in Early and Late Responses. Front Physiol (2011) 0.92
Pretreatment with stress cortisol enhances the human systemic inflammatory response to bacterial endotoxin. Crit Care Med (2009) 0.91
Phosphatase-dependent regulation of epithelial mitogen-activated protein kinase responses to toxin-induced membrane pores. PLoS One (2009) 0.91
Differential functional genomic effects of anti-inflammatory phytocompounds on immune signaling. BMC Genomics (2010) 0.91
Map kinase phosphatase 5 protects against sepsis-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol (2012) 0.90
Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to Lipopolysaccharide. J Immunol (2015) 0.89
Transcriptome analysis of renal ischemia/reperfusion injury and its modulation by ischemic pre-conditioning or hemin treatment. PLoS One (2012) 0.88
Parthenolide inhibits ERK and AP-1 which are dysregulated and contribute to excessive IL-8 expression and secretion in cystic fibrosis cells. J Inflamm (Lond) (2011) 0.88
Cutting edge: Expression of the transcription factor E74-like factor 4 is regulated by the mammalian target of rapamycin pathway in CD8+ T cells. J Immunol (2010) 0.87
Dusp5 negatively regulates IL-33-mediated eosinophil survival and function. EMBO J (2014) 0.87
Control of host cell phosphorylation by legionella pneumophila. Front Microbiol (2011) 0.87
Mapping MKP-3/FOXO1 interaction and evaluating the effect on gluconeogenesis. PLoS One (2012) 0.87
Ca-dependent Ras/Erk signaling mediates negative selection of autoreactive B cells. Small GTPases (2011) 0.86
Sensing of dietary lipids by enterocytes: a new role for SR-BI/CLA-1. PLoS One (2009) 0.86
Mechanism of upregulation of the inhibitory regulator, src-like adaptor protein (SLAP), by glucocorticoids in mast cells. Mol Immunol (2008) 0.86
TLR cross-talk confers specificity to innate immunity. Int Rev Immunol (2014) 0.86
Eukaryotic signaling pathways targeted by Salmonella effector protein AvrA in intestinal infection in vivo. BMC Microbiol (2010) 0.86
Phevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expression. PLoS One (2012) 0.85
Anti-inflammatory effects of mapracorat, a novel selective glucocorticoid receptor agonist, is partially mediated by MAP kinase phosphatase-1 (MKP-1). J Biol Chem (2012) 0.85
WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-inflammatory properties via MKP-1 in LPS-stimulated RAW264.7 macrophages. Br J Pharmacol (2015) 0.85
IL-2 and IL-4 stimulate MEK1 expression and contribute to T cell resistance against suppression by TGF-beta and IL-10 in asthma. J Immunol (2010) 0.84
Regulation of TCR signalling by tyrosine phosphatases: from immune homeostasis to autoimmunity. Immunology (2012) 0.83
Obesity accelerates T cell senescence in murine visceral adipose tissue. J Clin Invest (2016) 0.82
Transcriptome sequencing reveals a profile that corresponds to genomic variants in Waldenström macroglobulinemia. Blood (2016) 0.82
Salubrinal acts as a Dusp2 inhibitor and suppresses inflammation in anti-collagen antibody-induced arthritis. Cell Signal (2015) 0.81
Immunoregulatory Effects Triggered by Lactic Acid Bacteria Exopolysaccharides: New Insights into Molecular Interactions with Host Cells. Microorganisms (2016) 0.81
p38 MAPK Signaling in Pemphigus: Implications for Skin Autoimmunity. Autoimmune Dis (2013) 0.81
DNA methylation patterns of ulcer-healing genes associated with the normal gastric mucosa of gastric cancers. J Korean Med Sci (2010) 0.81
Highly recurrent mutations of SGK1, DUSP2 and JUNB in nodular lymphocyte predominant Hodgkin lymphoma. Leukemia (2015) 0.81
Early postinjury exercise reverses memory deficits and retards the progression of closed-head injury in mice. J Physiol (2012) 0.80
The molecular fingerprint of lung inflammation after blunt chest trauma. Eur J Med Res (2015) 0.80
Manganese modulation of MAPK pathways: effects on upstream mitogen activated protein kinase kinases and mitogen activated kinase phosphatase-1 in microglial cells. J Appl Toxicol (2011) 0.80
MEK/ERK pathway mediates insulin-promoted degradation of MKP-3 protein in liver cells. Mol Cell Endocrinol (2012) 0.80
12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity. Exp Mol Med (2012) 0.79
A novel anti-mycobacterial function of mitogen-activated protein kinase phosphatase-1. BMC Immunol (2009) 0.79
Gene trap mice reveal an essential function of dual specificity phosphatase Dusp16/MKP-7 in perinatal survival and regulation of Toll-like receptor (TLR)-induced cytokine production. J Biol Chem (2013) 0.79
Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells. Sci Rep (2016) 0.78
Epidermal RAF prevents allergic skin disease. Elife (2016) 0.78
Early gene expression changes with rush immunotherapy. Clin Mol Allergy (2011) 0.78
Src-like adaptor protein (SLAP) is upregulated in antigen-stimulated mast cells and acts as a negative regulator. Mol Immunol (2009) 0.78
Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice. Mucosal Immunol (2014) 0.77
Emerging Roles of the Mitogen and Stress Activated Kinases MSK1 and MSK2. Front Cell Dev Biol (2016) 0.77
Phosphotyrosine Substrate Sequence Motifs for Dual Specificity Phosphatases. PLoS One (2015) 0.77
Mechanisms of crystalline silica-induced pulmonary toxicity revealed by global gene expression profiling. Inhal Toxicol (2011) 0.77
MicroRNA expression profiles differentiate chronic pain condition subtypes. Transl Res (2015) 0.77
Concomitant BET and MAPK blockade for effective treatment of ovarian cancer. Oncotarget (2016) 0.76
Caloric restriction induces heat shock response and inhibits B16F10 cell tumorigenesis both in vitro and in vivo. Aging (Albany NY) (2015) 0.76
Tetraspanin CD151 Is a Negative Regulator of FcεRI-Mediated Mast Cell Activation. J Immunol (2015) 0.76
Genome-wide profiling of in vivo LPS-responsive genes in splenic myeloid cells. Mol Cells (2013) 0.76
Age-related changes in monocytes exacerbate neointimal hyperplasia after vascular injury. Oncotarget (2015) 0.76
Hypoxia Potentiates Palmitate-induced Pro-inflammatory Activation of Primary Human Macrophages. J Biol Chem (2015) 0.76
pCAP-based peptide substrates: the new tool in the box of tyrosine phosphatase assays. Methods (2013) 0.75
Transcriptional Profiling of Th2 Cells Identifies Pathogenic Features Associated with Asthma. J Immunol (2016) 0.75
Mechanistic systems biology of inflammatory gene expression in airway smooth muscle as tool for asthma drug development. Curr Drug Discov Technol (2008) 0.75
Differential responses of normal human melanocytes to intra- and extracellular dsRNA. DNA Cell Biol (2015) 0.75
Oxidants induce a corticosteroid-insensitive phosphorylation of histone 3 at serine 10 in monocytes. PLoS One (2015) 0.75
Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis. Nucleic Acids Res (2013) 0.75
Anti-Inflammatory Effects of β2-Receptor Agonists Salbutamol and Terbutaline Are Mediated by MKP-1. PLoS One (2016) 0.75
In vitro studies on the antimicrobial peptide human beta-defensin 9 (HBD9): signalling pathways and pathogen-related response (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc (2014) 0.75
Long-time treatment by low-dose N-acetyl-L-cysteine enhances proinflammatory cytokine expressions in LPS-stimulated macrophages. PLoS One (2014) 0.75
Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease. PLoS Genet (2017) 0.75
Dual specificity phosphatase 1 regulates human inducible nitric oxide synthase expression by p38 MAP kinase. Mediators Inflamm (2011) 0.75
Enhancement of macrophage inflammatory responses by CCL2 is correlated with increased miR-9 expression and downregulation of the ERK1/2 phosphatase Dusp6. Cell Immunol (2017) 0.75
The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases. Biochem Soc Trans (2016) 0.75
Role of protein tyrosine phosphatase non-receptor type 7 in the regulation of TNF-α production in RAW 264.7 macrophages. PLoS One (2013) 0.75
The transcription factor Gli3 promotes B cell development in fetal liver through repression of Shh. J Exp Med (2017) 0.75
Gene expression patterns induced at different stages of rhinovirus infection in human alveolar epithelial cells. PLoS One (2017) 0.75
Crosstalk between Signaling Pathways in Pemphigus: A Role for Endoplasmic Reticulum Stress in p38 Mitogen-Activated Protein Kinase Activation? Front Immunol (2017) 0.75
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity (2008) 3.67
SOCS3 regulates the plasticity of gp130 signaling. Nat Immunol (2003) 3.45
Colloquium paper: genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proc Natl Acad Sci U S A (2010) 3.20
High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay. RNA (2008) 3.13
Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock. J Exp Med (2005) 2.83
Interferon-regulatory-factor 1 controls Toll-like receptor 9-mediated IFN-beta production in myeloid dendritic cells. Eur J Immunol (2007) 2.62
E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex. Gastroenterology (2009) 2.35
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation. J Exp Med (2009) 2.03
Distribution of Y chromosomes among native North Americans: a study of Athapaskan population history. Am J Phys Anthropol (2008) 2.02
Opposing functions of IKKbeta during acute and chronic intestinal inflammation. Proc Natl Acad Sci U S A (2008) 1.90
Multiple gene expression classifiers from different array platforms predict poor prognosis of colorectal cancer. Clin Cancer Res (2007) 1.89
Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling. J Leukoc Biol (2007) 1.81
Extracellular and intracellular pattern recognition receptors cooperate in the recognition of Helicobacter pylori. Gastroenterology (2009) 1.57
Control of dual-specificity phosphatase-1 expression in activated macrophages by IL-10. Eur J Immunol (2005) 1.56
The phosphoproteome of toll-like receptor-activated macrophages. Mol Syst Biol (2010) 1.55
Differential recognition of TLR-dependent microbial ligands in human bronchial epithelial cells. J Immunol (2007) 1.53
Autocrine IL-10 induces hallmarks of alternative activation in macrophages and suppresses antituberculosis effector mechanisms without compromising T cell immunity. J Immunol (2009) 1.47
Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells. Eur J Immunol (2008) 1.46
Identification of a TLR4- and TRIF-dependent activation program of dendritic cells. Eur J Immunol (2004) 1.39
Tristetraprolin is required for full anti-inflammatory response of murine macrophages to IL-10. J Immunol (2009) 1.37
Embryonic endothelial progenitor cells expressing a broad range of proangiogenic and remodeling factors enhance vascularization and tissue recovery in acute and chronic ischemia. FASEB J (2005) 1.33
Highly sensitive detection of early-stage pancreatic cancer by multimodal near-infrared molecular imaging in living mice. Int J Cancer (2008) 1.31
Double-stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-mediated differential signaling. J Immunol (2008) 1.30
Toll-like receptor-dependent activation of antigen-presenting cells affects adaptive immunity to Helicobacter pylori. Gastroenterology (2007) 1.23
Microarray-based prediction of tumor response to neoadjuvant radiochemotherapy of patients with locally advanced rectal cancer. Clin Gastroenterol Hepatol (2008) 1.16
Transcriptional activation induced in macrophages by Toll-like receptor (TLR) ligands: from expression profiling to a model of TLR signaling. Eur J Immunol (2004) 1.12
Unexpected NRY chromosome variation in Northern Island Melanesia. Mol Biol Evol (2006) 1.12
Secreted frizzled-related protein 1 extrinsically regulates cycling activity and maintenance of hematopoietic stem cells. Cell Stem Cell (2009) 1.10
Cellular target genes of Epstein-Barr virus nuclear antigen 2. J Virol (2006) 1.10
Differential gene expression patterns of EBV infected EBNA-3A positive and negative human B lymphocytes. PLoS Pathog (2009) 1.09
The Druze: a population genetic refugium of the Near East. PLoS One (2008) 1.08
Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A. Nucleic Acids Res (2006) 1.08
MyD88-dependent changes in the pulmonary transcriptome after infection with Chlamydia pneumoniae. Physiol Genomics (2007) 1.03
Enhanced activation of epidermal growth factor receptor caused by tumor-derived E-cadherin mutations. Cancer Res (2008) 1.01
Pronounced phenotype in activated regulatory T cells during a chronic helminth infection. J Immunol (2009) 1.01
Stable knock-down of the sphingosine 1-phosphate receptor S1P1 influences multiple functions of human endothelial cells. Arterioscler Thromb Vasc Biol (2004) 1.01
Diagnostic management of patients with SAPHO syndrome: use of MR imaging to guide bone biopsy at CT for microbiological and histological work-up. Eur Radiol (2003) 0.91
Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs. Exp Hematol (2008) 0.88
Functional allelic loss detected at the protein level in archival human tumours using allele-specific E-cadherin monoclonal antibodies. J Pathol (2002) 0.88
End-of-life care in Canada. Clin Invest Med (2013) 0.88
Organ-specific role of MyD88 for gene regulation during polymicrobial peritonitis. Infect Immun (2006) 0.86
Phylogenetics of worldwide human populations as determined by polymorphic Alu insertions. Electrophoresis (2002) 0.86
Airborne indoor particles from schools are more toxic than outdoor particles. Am J Respir Cell Mol Biol (2012) 0.85
Increased inflammation and impaired resistance to Chlamydophila pneumoniae infection in Dusp1(-/-) mice: critical role of IL-6. J Leukoc Biol (2010) 0.85
Mycobacteria-induced granuloma necrosis depends on IRF-1. J Cell Mol Med (2008) 0.83
Tissue-specific induction of ADAMTS2 in monocytes and macrophages by glucocorticoids. J Mol Med (Berl) (2007) 0.82
Are we ready to build health systems that consider the climate? J Health Serv Res Policy (2013) 0.80
Retinoic acid-induced nNOS expression depends on a novel PI3K/Akt/DAX1 pathway in human TGW-nu-I neuroblastoma cells. Am J Physiol Cell Physiol (2009) 0.80
Y-chromosomal STR haplotypes in Berber and Arabic-speaking populations from Morocco. Forensic Sci Int (2004) 0.79
Motility enhancement by tumor-derived mutant E-cadherin is sensitive to treatment with epidermal growth factor receptor and phosphatidylinositol 3-kinase inhibitors. Exp Cell Res (2002) 0.77
Enhanced basal AP-1 activity and de-regulation of numerous genes in T cells transgenic for a dominant interfering mutant of FADD/MORT1. Eur J Immunol (2004) 0.76
Safety of spinal endoscopy is contingent on basic image interpretation. Reg Anesth Pain Med (2002) 0.75
Comment on fluoroscopic interlaminar epidural steroid injections. Pain Physician (2004) 0.75
Corrigendum: Geographic population structure analysis of worldwide human populations infers their biogeographical origins. Nat Commun (2016) 0.75
Balancing protection and pragmatism: a framework for NGO accountability in rights-based approaches. Health Hum Rights (2006) 0.75
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