Published in PLoS One on February 05, 2016
MAP kinases in the immune response. Annu Rev Immunol (2001) 7.62
Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials. Lancet (2009) 4.40
Dual-specificity phosphatases: critical regulators with diverse cellular targets. Biochem J (2009) 3.98
Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses. Proc Natl Acad Sci U S A (2006) 3.74
MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock. J Exp Med (2005) 3.37
MAPK phosphatases--regulating the immune response. Nat Rev Immunol (2007) 3.16
Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death, and cancer. Pharmacol Rev (2008) 2.75
Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1. J Exp Med (2006) 2.46
DUSP meet immunology: dual specificity MAPK phosphatases in control of the inflammatory response. J Immunol (2006) 2.36
Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38. Mol Cell Biol (2002) 2.10
Cutting edge: macrophage inhibition by cyclic AMP (cAMP): differential roles of protein kinase A and exchange protein directly activated by cAMP-1. J Immunol (2005) 2.01
Regulation of the immune response by stress-activated protein kinases. Immunol Rev (2009) 2.00
Roflumilast with long-acting β2-agonists for COPD: influence of exacerbation history. Eur Respir J (2011) 1.99
Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling. FEBS J (2012) 1.86
The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation. Biochim Biophys Acta (2010) 1.85
SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung. Am J Physiol Lung Cell Mol Physiol (2000) 1.75
Pharmacology and therapeutics of bronchodilators. Pharmacol Rev (2012) 1.72
Signaling by the phosphatase MKP-1 in dendritic cells imprints distinct effector and regulatory T cell fates. Immunity (2011) 1.65
Structure, mapping, and expression of erp, a growth factor-inducible gene encoding a nontransmembrane protein tyrosine phosphatase, and effect of ERP on cell growth. Mol Cell Biol (1993) 1.62
Isolation and characterization of a human dual specificity protein-tyrosine phosphatase gene. J Biol Chem (1994) 1.55
β2-agonist therapy in lung disease. Am J Respir Crit Care Med (2013) 1.27
Increased inflammation, impaired bacterial clearance, and metabolic disruption after gram-negative sepsis in Mkp-1-deficient mice. J Immunol (2009) 1.27
Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation--a potential mechanism. Eur J Immunol (2001) 1.22
Activation of G protein-coupled receptors. Adv Protein Chem (2007) 1.20
Transcriptional regulation of human dual specificity protein phosphatase 1 (DUSP1) gene by glucocorticoids. PLoS One (2010) 1.12
Regulation of innate immunity by MAPK dual-specificity phosphatases: knockout models reveal new tricks of old genes. J Leukoc Biol (2007) 1.09
Mitogen-activated protein kinase phosphatase (MKP)-1 in immunology, physiology, and disease. Life Sci (2011) 1.08
β2-Adrenoreceptors of regulatory lymphocytes are essential for vagal neuromodulation of the innate immune system. FASEB J (2011) 1.03
Anti-inflammatory effects of theophylline, cromolyn and salbutamol in a murine model of pleurisy. Br J Pharmacol (1996) 1.01
Effect of beta2-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human ASM cells: a role for protein kinase A. Am J Physiol Lung Cell Mol Physiol (2008) 0.98
Phosphodiesterase 4B mediates extracellular signal-regulated kinase-dependent up-regulation of mucin MUC5AC protein by Streptococcus pneumoniae by inhibiting cAMP-protein kinase A-dependent MKP-1 phosphatase pathway. J Biol Chem (2012) 0.98
Tangeretin suppresses IL-1beta-induced cyclooxygenase (COX)-2 expression through inhibition of p38 MAPK, JNK, and AKT activation in human lung carcinoma cells. Biochem Pharmacol (2006) 0.98
Cyclic AMP inhibits JNK activation by CREB-mediated induction of c-FLIP(L) and MKP-1, thereby antagonizing UV-induced apoptosis. Cell Death Differ (2008) 0.95
Salmeterol with fluticasone enhances the suppression of IL-8 release and increases the translocation of glucocorticoid receptor by human neutrophils stimulated with cigarette smoke. J Mol Med (Berl) (2008) 0.93
Mitogen-activated protein kinase phosphatase-1 negatively regulates the expression of interleukin-6, interleukin-8, and cyclooxygenase-2 in A549 human lung epithelial cells. J Pharmacol Exp Ther (2010) 0.91
Lung myofibroblasts as targets of salmeterol and fluticasone propionate: inhibition of alpha-SMA and NF-kappaB. Int Immunol (2005) 0.88
Mitogen-activated protein kinase phosphatase 1 as an inflammatory factor and drug target. Basic Clin Pharmacol Toxicol (2013) 0.88
Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism. Mediators Inflamm (2012) 0.87
Regulation of cartilage formation and maturation by mitogen-activated protein kinase signaling. Birth Defects Res C Embryo Today (2008) 0.87
Differential effects of SB 242235, a selective p38 mitogen-activated protein kinase inhibitor, on IL-1 treated bovine and human cartilage/chondrocyte cultures. Osteoarthritis Cartilage (2000) 0.87
MAPK phosphatase-1 (MKP-1) expression is up-regulated by hCG/cAMP and modulates steroidogenesis in MA-10 Leydig cells. Endocrinology (2011) 0.86
Can the anti-inflammatory activities of β2-agonists be harnessed in the clinical setting? Drug Des Devel Ther (2013) 0.86
Attenuation of the acute inflammatory response by dual specificity phosphatase 1 by inhibition of p38 MAP kinase. Mol Immunol (2011) 0.85
Long-acting β2-agonists increase fluticasone propionate-induced mitogen-activated protein kinase phosphatase 1 (MKP-1) in airway smooth muscle cells. PLoS One (2013) 0.85
Inhibitors of Phosphodiesterase 4, but Not Phosphodiesterase 3, Increase β2-Agonist-Induced Expression of Antiinflammatory Mitogen-Activated Protein Kinase Phosphatase 1 in Airway Smooth Muscle Cells. Am J Respir Cell Mol Biol (2015) 0.84
SD0006: a potent, selective and orally available inhibitor of p38 kinase. Pharmacology (2009) 0.84
The expression of interleukin-12 is increased by MAP kinase phosphatase-1 through a mechanism related to interferon regulatory factor 1. Mol Immunol (2012) 0.84
Activation of p38 mitogen-activated protein kinase in ovalbumin and ozone-induced mouse model of asthma. Respirology (2013) 0.82
Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1. Br J Pharmacol (2013) 0.81
Effects of adrenoceptor agonists and antagonists on morphine-induced Straub tail in mice. Pharmacol Biochem Behav (2002) 0.81
Coal-induced interleukin-6 gene expression is mediated through ERKs and p38 MAPK pathways. Toxicol Appl Pharmacol (2003) 0.76