NMR studies of dynamics in RNA and DNA by 13C relaxation.

PubWeight™: 1.24‹?› | Rank: Top 10%

🔗 View Article (PMID 17154290)

Published in Biopolymers on July 03, 2007

Authors

Zahra Shajani1, Gabriele Varani

Author Affiliations

1: Department of Chemistry, University of Washington, Seattle, WA 98195-1700, USA.

Articles citing this

Strong correlation between SHAPE chemistry and the generalized NMR order parameter (S2) in RNA. J Am Chem Soc (2008) 2.26

Slow conformational dynamics at C2'-endo nucleotides in RNA. J Am Chem Soc (2008) 1.35

Extensive backbone dynamics in the GCAA RNA tetraloop analyzed using 13C NMR spin relaxation and specific isotope labeling. J Am Chem Soc (2008) 1.24

How binding of small molecule and peptide ligands to HIV-1 TAR alters the RNA motional landscape. Nucleic Acids Res (2009) 1.20

Hydration dependent dynamics in RNA. J Biomol NMR (2009) 1.17

Unwinding RNA's secrets: advances in the biology, physics, and modeling of complex RNAs. Curr Opin Struct Biol (2008) 1.10

NMR and MD studies of the temperature-dependent dynamics of RNA YNMG-tetraloops. Nucleic Acids Res (2008) 1.07

Solid-state deuterium NMR studies reveal micros-ns motions in the HIV-1 transactivation response RNA recognition site. J Am Chem Soc (2008) 1.05

Site-specific DNA structural and dynamic features revealed by nucleotide-independent nitroxide probes. Biochemistry (2009) 0.97

Domain-elongation NMR spectroscopy yields new insights into RNA dynamics and adaptive recognition. RNA (2009) 0.96

Enzymatic de novo pyrimidine nucleotide synthesis. J Am Chem Soc (2010) 0.95

Probing sequence-specific DNA flexibility in a-tracts and pyrimidine-purine steps by nuclear magnetic resonance (13)C relaxation and molecular dynamics simulations. Biochemistry (2012) 0.93

Theory of nonrigid rotational motion applied to NMR relaxation in RNA. J Phys Chem A (2011) 0.91

Deriving quantitative dynamics information for proteins and RNAs using ROTDIF with a graphical user interface. J Biomol NMR (2013) 0.88

Slow exchange model of nonrigid rotational motion in RNA for combined solid-state and solution NMR studies. J Phys Chem B (2010) 0.86

Probing complexes with single fluorophores: factors contributing to dispersion of FRET in DNA/RNA duplexes. Eur Biophys J (2008) 0.86

Structural fidelity and NMR relaxation analysis in a prototype RNA hairpin. RNA (2015) 0.84

Nucleic acid helix structure determination from NMR proton chemical shifts. J Biomol NMR (2013) 0.83

Preparation, resonance assignment, and preliminary dynamics characterization of residue specific 13C/15N-labeled elongated DNA for the study of sequence-directed dynamics by NMR. J Biomol NMR (2009) 0.83

RNA phosphodiester backbone dynamics of a perdeuterated cUUCGg tetraloop RNA from phosphorus-31 NMR relaxation analysis. J Biomol NMR (2009) 0.81

Conserved nucleotides in an RNA essential for hepatitis B virus replication show distinct mobility patterns. Nucleic Acids Res (2007) 0.80

Magnetic resonance access to transiently formed protein complexes. ChemistryOpen (2014) 0.79

Elucidating molecular motion through structural and dynamic filters of energy-minimized conformer ensembles. J Phys Chem B (2014) 0.79

Preparation of selective and segmentally labeled single-stranded DNA for NMR by self-primed PCR and asymmetrical endonuclease double digestion. Nucleic Acids Res (2009) 0.78

Divide and conquer is always best: sensitivity of methyl correlation experiments. J Biomol NMR (2013) 0.77

Effect of local sugar and base geometry on 13C and 15N magnetic shielding anisotropy in DNA nucleosides. J Biomol NMR (2008) 0.76

Recent Methods for Purification and Structure Determination of Oligonucleotides. Int J Mol Sci (2016) 0.75

Synthesis and incorporation of 13C-labeled DNA building blocks to probe structural dynamics of DNA by NMR. Nucleic Acids Res (2017) 0.75

Articles by these authors

Design of a novel globular protein fold with atomic-level accuracy. Science (2003) 13.06

RNA-binding proteins: modular design for efficient function. Nat Rev Mol Cell Biol (2007) 5.33

The structure and function of small nucleolar ribonucleoproteins. Nucleic Acids Res (2007) 2.50

Strong correlation between SHAPE chemistry and the generalized NMR order parameter (S2) in RNA. J Am Chem Soc (2008) 2.26

Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein. EMBO J (2003) 2.01

Protein families and RNA recognition. FEBS J (2005) 1.65

The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs. Nat Struct Mol Biol (2005) 1.52

High-resolution structural and thermodynamic analysis of extreme stabilization of human procarboxypeptidase by computational protein design. J Mol Biol (2006) 1.49

Structure of stem-loop IV of Tetrahymena telomerase RNA. EMBO J (2006) 1.49

The highly cooperative folding of small naturally occurring proteins is likely the result of natural selection. Cell (2007) 1.46

Rational design of inhibitors of HIV-1 TAR RNA through the stabilisation of electrostatic "hot spots". J Mol Biol (2004) 1.37

Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein. Proc Natl Acad Sci U S A (2009) 1.33

Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain. Nat Struct Mol Biol (2010) 1.32

A conserved RNA structure within the HCV IRES eIF3-binding site. Nat Struct Biol (2002) 1.31

An all-atom, distance-dependent scoring function for the prediction of protein-DNA interactions from structure. Proteins (2007) 1.28

Structural genomics of infectious disease drug targets: the SSGCID. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 1.27

A new hydrogen-bonding potential for the design of protein-RNA interactions predicts specific contacts and discriminates decoys. Nucleic Acids Res (2004) 1.27

A knowledge-based potential function predicts the specificity and relative binding energy of RNA-binding proteins. FEBS J (2007) 1.26

Structure-guided peptidomimetic design leads to nanomolar beta-hairpin inhibitors of the Tat-TAR interaction of bovine immunodeficiency virus. Biochemistry (2007) 1.20

How binding of small molecule and peptide ligands to HIV-1 TAR alters the RNA motional landscape. Nucleic Acids Res (2009) 1.20

The C-terminal domains of vertebrate CstF-64 and its yeast orthologue Rna15 form a new structure critical for mRNA 3'-end processing. J Biol Chem (2006) 1.20

Real-time multidimensional NMR follows RNA folding with second resolution. Proc Natl Acad Sci U S A (2010) 1.18

13C NMR relaxation studies of RNA base and ribose nuclei reveal a complex pattern of motions in the RNA binding site for human U1A protein. J Mol Biol (2005) 1.18

Hydration dependent dynamics in RNA. J Biomol NMR (2009) 1.17

A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III. EMBO J (2004) 1.12

Structural mimicry of retroviral tat proteins by constrained beta-hairpin peptidomimetics: ligands with high affinity and selectivity for viral TAR RNA regulatory elements. J Am Chem Soc (2004) 1.11

TAR RNA recognition by a cyclic peptidomimetic of Tat protein. Biochemistry (2005) 1.09

How arginine-rich domains coordinate mRNA maturation events. RNA Biol (2007) 1.07

Protein and RNA dynamics play key roles in determining the specific recognition of GU-rich polyadenylation regulatory elements by human Cstf-64 protein. J Mol Biol (2005) 1.07

Structure and stability of wild-type and mutant RNA internal loops from the SL-1 domain of the HIV-1 packaging signal. J Mol Biol (2002) 1.07

The solution structure of an essential stem-loop of human telomerase RNA. Nucleic Acids Res (2003) 1.06

Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone). Chem Biol (2009) 1.06

The structure of an enzyme-activating fragment of human telomerase RNA. RNA (2005) 1.06

Engineering RNA-binding proteins for biology. FEBS J (2013) 1.06

γ-AApeptides bind to RNA by mimicking RNA-binding proteins. Org Biomol Chem (2011) 1.06

Validation of automated docking programs for docking and database screening against RNA drug targets. J Med Chem (2004) 1.05

Solid-state deuterium NMR studies reveal micros-ns motions in the HIV-1 transactivation response RNA recognition site. J Am Chem Soc (2008) 1.05

Binding of U1A protein changes RNA dynamics as observed by 13C NMR relaxation studies. Biochemistry (2007) 1.05

Essential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat protein. Nucleic Acids Res (2010) 1.00

Novel protein-protein contacts facilitate mRNA 3'-processing signal recognition by Rna15 and Hrp1. J Mol Biol (2010) 1.00

The box H/ACA RNP assembly factor Naf1p contains a domain homologous to Gar1p mediating its interaction with Cbf5p. J Mol Biol (2007) 0.99

Inhibition of both HIV-1 reverse transcription and gene expression by a cyclic peptide that binds the Tat-transactivating response element (TAR) RNA. PLoS Pathog (2011) 0.97

High-resolution structural validation of the computational redesign of human U1A protein. Structure (2006) 0.96

Design of beta-hairpin peptidomimetics that inhibit binding of alpha-helical HIV-1 Rev protein to the rev response element RNA. Angew Chem Int Ed Engl (2007) 0.95

Mitoxantrone analogues as ligands for a stem-loop structure of tau pre-mRNA. J Med Chem (2009) 0.94

Monitoring tat peptide binding to TAR RNA by solid-state 31P-19F REDOR NMR. Nucleic Acids Res (2005) 0.94

Cell-free production of functional Plasmodium falciparum dihydrofolate reductase-thymidylate synthase. Mol Biochem Parasitol (2006) 0.93

Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals. J Mol Biol (2007) 0.93

Mis-translation of a computationally designed protein yields an exceptionally stable homodimer: implications for protein engineering and evolution. J Mol Biol (2006) 0.93

The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development. Biochem J (2011) 0.91

13C relaxation studies of the DNA target sequence for hhai methyltransferase reveal unique motional properties. Biochemistry (2008) 0.91

Theory of nonrigid rotational motion applied to NMR relaxation in RNA. J Phys Chem A (2011) 0.91

A model for C74 addition by CCA-adding enzymes: C74 addition, like C75 and A76 addition, does not involve tRNA translocation. J Biol Chem (2006) 0.89

Intermediate rate atomic trajectories of RNA by solid-state NMR spectroscopy. J Am Chem Soc (2010) 0.89

The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic. Genes Dev (2011) 0.87

Contrasting views of the internal dynamics of the HhaI methyltransferase target DNA reported by solution and solid-state NMR spectroscopy. J Am Chem Soc (2006) 0.87

How a rotavirus hijacks the human protein synthesis machinery. Nat Struct Biol (2002) 0.87

Slow exchange model of nonrigid rotational motion in RNA for combined solid-state and solution NMR studies. J Phys Chem B (2010) 0.86

Solution structure of the influenza A virus cRNA promoter: implications for differential recognition of viral promoter structures by RNA-dependent RNA polymerase. Nucleic Acids Res (2003) 0.85

A small-molecule probe induces a conformation in HIV TAR RNA capable of binding drug-like fragments. J Mol Biol (2011) 0.85

Molecular dynamics simulation of the RNA complex of a double-stranded RNA-binding domain reveals dynamic features of the intermolecular interface and its hydration. Biophys J (2002) 0.85

Multivalent drug design and inhibition of cholera toxin by specific and transient protein-ligand interactions. Chem Biol Drug Des (2008) 0.85

Furanose dynamics in the HhaI methyltransferase target DNA studied by solution and solid-state NMR relaxation. J Phys Chem B (2008) 0.85

The box H/ACA snoRNP assembly factor Shq1p is a chaperone protein homologous to Hsp90 cochaperones that binds to the Cbf5p enzyme. J Mol Biol (2009) 0.83

Identification of the optimal third generation antifolate against P. falciparum and P. vivax. Mol Biochem Parasitol (2005) 0.83

miRNA sensitivity to Drosha levels correlates with pre-miRNA secondary structure. RNA (2014) 0.82

A novel small-molecule binds to the influenza A virus RNA promoter and inhibits viral replication. Chem Commun (Camb) (2013) 0.82

Independent alignment of RNA for dynamic studies using residual dipolar couplings. J Biomol NMR (2012) 0.82

Cell-free selection of RNA-binding proteins using in vitro compartmentalization. Nucleic Acids Res (2008) 0.82

Decoding RNA motional codes. Trends Biochem Sci (2006) 0.82

Nop10 is a conserved H/ACA snoRNP molecular adaptor. Biochemistry (2008) 0.82

The interactome of the atypical phosphatase Rtr1 in Saccharomyces cerevisiae. Mol Biosyst (2014) 0.81

13C/15N-19F intermolecular REDOR NMR study of the interaction of TAR RNA with Tat peptides. J Am Chem Soc (2010) 0.81

Examining the relationship between RNA function and motion using nuclear magnetic resonance. Wiley Interdiscip Rev RNA (2011) 0.81

Finding the missing code of RNA recognition by PUF proteins. Chem Biol (2011) 0.81

Differential drug binding by the highly conserved Plasmodium falciparum thymidylate synthase. Mol Biochem Parasitol (2005) 0.80

Fragment-based discovery of novel thymidylate synthase leads by NMR screening and group epitope mapping. Chem Biol Drug Des (2010) 0.80

Elucidating molecular motion through structural and dynamic filters of energy-minimized conformer ensembles. J Phys Chem B (2014) 0.79

Structural and biochemical analysis of the assembly and function of the yeast pre-mRNA 3' end processing complex CF I. Proc Natl Acad Sci U S A (2012) 0.79

Aminoglycoside antibiotics bind to the influenza A virus RNA promoter. Mol Biosyst (2012) 0.78

Molecular dynamics simulations identify time scale of conformational changes responsible for conformational selection in molecular recognition of HIV-1 transactivation responsive RNA. J Am Chem Soc (2014) 0.78

GFT projection NMR for efficient (1)H/ (13)C sugar spin system identification in nucleic acids. J Biomol NMR (2012) 0.77

Correction to "Theory of nonrigid rotational motion applied to NMR relaxation in RNA". J Phys Chem A (2012) 0.77

Locking out viral replication. Nat Chem Biol (2009) 0.76

Structural biology: RNA switches function. Nature (2006) 0.76

Splicing factor 1 in the pocket. Structure (2003) 0.76

Preparation of RNA samples with narrow line widths for solid state NMR investigations. J Magn Reson (2012) 0.76

Comparative analysis of glutaredoxin domains from bacterial opportunistic pathogens. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.75

Ultraslow Domain Motions in HIV-1 TAR RNA Revealed by Solid-State Deuterium NMR. J Phys Chem B (2016) 0.75

1H, 13C and 15N resonance assignments of URNdesign, a computationally redesigned RRM protein. J Biomol NMR (2005) 0.75

Interactions of protein side chains with RNA defined with REDOR solid state NMR. J Biomol NMR (2011) 0.75