Published in Cell Stem Cell on May 08, 2009
Single-cell dissection of transcriptional heterogeneity in human colon tumors. Nat Biotechnol (2011) 7.84
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Cell (2012) 3.91
Nerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells. Cell Stem Cell (2011) 3.19
Identification of the cell lineage at the origin of basal cell carcinoma. Nat Cell Biol (2010) 2.97
Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nat Cell Biol (2012) 2.51
The circadian molecular clock creates epidermal stem cell heterogeneity. Nature (2011) 2.34
Prospective identification and purification of quiescent adult neural stem cells from their in vivo niche. Neuron (2014) 2.25
Identifying the cellular origin of squamous skin tumors. Proc Natl Acad Sci U S A (2011) 2.24
Epithelial stem cells, wound healing and cancer. Nat Rev Cancer (2012) 2.23
Epidermal stem cell diversity and quiescence. EMBO Mol Med (2009) 2.14
Wounding enhances epidermal tumorigenesis by recruiting hair follicle keratinocytes. Proc Natl Acad Sci U S A (2011) 1.89
The basement membrane of hair follicle stem cells is a muscle cell niche. Cell (2011) 1.88
Characterization of the intestinal cancer stem cell marker CD166 in the human and mouse gastrointestinal tract. Gastroenterology (2010) 1.86
Defining the origins of Ras/p53-mediated squamous cell carcinoma. Proc Natl Acad Sci U S A (2011) 1.83
Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches. Nat Commun (2012) 1.77
Finding one's niche in the skin. Cell Stem Cell (2009) 1.77
Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis. Nat Protoc (2010) 1.72
25 years of epidermal stem cell research. J Invest Dermatol (2011) 1.70
Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations. J Clin Invest (2011) 1.65
The epidermis comprises autonomous compartments maintained by distinct stem cell populations. Cell Stem Cell (2013) 1.64
Targeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunities. Eur Respir J (2014) 1.59
Epithelial inflammation resulting from an inherited loss-of-function mutation in EGFR. J Invest Dermatol (2014) 1.58
Tracking adult stem cells. EMBO Rep (2011) 1.56
Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity. Cell Syst (2016) 1.44
Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin. Development (2011) 1.43
Cutaneous wound healing: recruiting developmental pathways for regeneration. Cell Mol Life Sci (2012) 1.40
Stem Cell Lineage Infidelity Drives Wound Repair and Cancer. Cell (2017) 1.39
LRIG1 Regulates Ontogeny of Smooth Muscle-Derived Subsets of Interstitial Cells of Cajal in Mice. Gastroenterology (2015) 1.38
Epithelial stem cells and implications for wound repair. Semin Cell Dev Biol (2012) 1.35
TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis. EMBO J (2011) 1.34
Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment. Cell Stem Cell (2011) 1.33
Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin. Mol Cell Biol (2010) 1.23
Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation. Nat Med (2014) 1.22
Hairy tale of signaling in hair follicle development and cycling. Semin Cell Dev Biol (2012) 1.22
The interfollicular epidermis of adult mouse tail comprises two distinct cell lineages that are differentially regulated by Wnt, Edaradd, and Lrig1. Stem Cell Reports (2013) 1.20
Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after injury. Development (2011) 1.15
Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche. Nat Rev Mol Cell Biol (2013) 1.13
Stem cell dynamics in the hair follicle niche. Semin Cell Dev Biol (2013) 1.08
Heterogeneity and plasticity of epidermal stem cells. Development (2014) 1.08
Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERα-positive breast cancer. Mol Cancer Res (2011) 1.08
Mechanisms regulating epidermal stem cells. EMBO J (2012) 1.07
Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation. Dev Biol (2010) 1.06
Dissecting the bulge in hair regeneration. J Clin Invest (2012) 1.03
Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells. Development (2013) 1.02
Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation. EMBO Mol Med (2010) 1.02
EGFR-ras-raf signaling in epidermal stem cells: roles in hair follicle development, regeneration, tissue remodeling and epidermal cancers. Int J Mol Sci (2013) 1.02
Necl2 regulates epidermal adhesion and wound repair. Development (2009) 1.01
Differentiation of progenitors in the liver: a matter of local choice. J Clin Invest (2013) 1.00
Tracking cells in their native habitat: lineage tracing in epithelial neoplasia. Nat Rev Cancer (2013) 1.00
Stem cells: Skin regeneration and repair. Nature (2010) 0.98
The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status. Neuro Oncol (2013) 0.97
c-MYC-induced sebaceous gland differentiation is controlled by an androgen receptor/p53 axis. Cell Rep (2013) 0.97
LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis. J Clin Invest (2013) 0.96
Stem cell dynamics in mouse hair follicles: a story from cell division counting and single cell lineage tracing. Cell Cycle (2010) 0.96
Markers of epidermal stem cell subpopulations in adult mammalian skin. Cold Spring Harb Perspect Med (2014) 0.95
LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor. Br J Cancer (2013) 0.95
Inflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression. Genes Dev (2013) 0.94
aPKCλ controls epidermal homeostasis and stem cell fate through regulation of division orientation. J Cell Biol (2013) 0.94
Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1. Development (2010) 0.93
Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments. Nat Rev Mol Cell Biol (2015) 0.93
Home sweet home: skin stem cell niches. Cell Mol Life Sci (2012) 0.92
LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development. J Pathol (2013) 0.92
Lrig2-deficient mice are protected against PDGFB-induced glioma. PLoS One (2013) 0.91
LRIG1 modulates cancer cell sensitivity to Smac mimetics by regulating TNFα expression and receptor tyrosine kinase signaling. Cancer Res (2012) 0.91
Wound healing and skin regeneration. Cold Spring Harb Perspect Med (2015) 0.91
Epidermal development in mammals: key regulators, signals from beneath, and stem cells. Int J Mol Sci (2013) 0.90
Understanding epithelial homeostasis in the intestine: An old battlefield of ideas, recent breakthroughs and remaining controversies. Tissue Barriers (2013) 0.90
SOX2 is a cancer-specific regulator of tumour initiating potential in cutaneous squamous cell carcinoma. Nat Commun (2014) 0.89
In vivo functional studies of tumor-specific retrogene NanogP8 in transgenic animals. Cell Cycle (2013) 0.89
Biochemistry of epidermal stem cells. Biochim Biophys Acta (2012) 0.88
Overexpression of epigen during embryonic development induces reversible, epidermal growth factor receptor-dependent sebaceous gland hyperplasia. Mol Cell Biol (2014) 0.88
Expression of Kruppel-like factor KLF4 in mouse hair follicle stem cells contributes to cutaneous wound healing. PLoS One (2012) 0.88
Epigenetic control of adult stem cell function. Nat Rev Mol Cell Biol (2016) 0.88
Delayed cutaneous wound healing and aberrant expression of hair follicle stem cell markers in mice selectively lacking Ctip2 in epidermis. PLoS One (2012) 0.88
Refining the role for adult stem cells as cancer cells of origin. Trends Cell Biol (2014) 0.88
Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen. Nat Commun (2014) 0.87
Actin filament dynamics impacts keratinocyte stem cell maintenance. EMBO Mol Med (2013) 0.87
Melanocytes, melanocyte stem cells, and melanoma stem cells. Clin Dermatol (2013) 0.87
H-ras expression in immortalized keratinocytes produces an invasive epithelium in cultured skin equivalents. PLoS One (2009) 0.87
Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development (2013) 0.87
Oral epithelial stem cells in tissue maintenance and disease: the first steps in a long journey. Int J Oral Sci (2013) 0.87
It's all in the details: methods in breast development and cancer. Breast Cancer Res (2009) 0.87
LRIG and cancer prognosis. Acta Oncol (2014) 0.87
Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse. PLoS Genet (2014) 0.87
Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications. Int J Mol Sci (2015) 0.86
BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny. Genes Dev (2012) 0.86
The LRIG family: enigmatic regulators of growth factor receptor signaling. Endocr Relat Cancer (2014) 0.86
Lineage analysis of epidermal stem cells. Cold Spring Harb Perspect Med (2014) 0.86
Endogenous retinoids in the hair follicle and sebaceous gland. Biochim Biophys Acta (2011) 0.85
The cell cycle regulator protein 14-3-3σ is essential for hair follicle integrity and epidermal homeostasis. J Invest Dermatol (2012) 0.85
The circadian clock in skin: implications for adult stem cells, tissue regeneration, cancer, aging, and immunity. J Biol Rhythms (2015) 0.85
Principles and mechanisms of regeneration in the mouse model for wound-induced hair follicle neogenesis. Regeneration (Oxf) (2015) 0.85
Sox4 links tumor suppression to accelerated aging in mice by modulating stem cell activation. Cell Rep (2014) 0.84
Stem cells in ectodermal development. J Mol Med (Berl) (2012) 0.84
Development and homeostasis of the skin epidermis. Cold Spring Harb Perspect Biol (2012) 0.84
Constitutive Stat3 activation alters behavior of hair follicle stem and progenitor cell populations. Mol Carcinog (2013) 0.84
Epiprofin orchestrates epidermal keratinocyte proliferation and differentiation. J Cell Sci (2014) 0.83
Transcriptional dissection of human limbal niche compartments by massive parallel sequencing. PLoS One (2013) 0.83
Deregulation of epidermal stem cell niche contributes to pathogenesis of nonhealing venous ulcers. Wound Repair Regen (2014) 0.81
Identification of c-MYC as a target of the APC pathway. Science (1998) 24.25
Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell (1990) 12.13
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell (2004) 10.79
Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell (2008) 9.92
Socializing with the neighbors: stem cells and their niche. Cell (2004) 9.40
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. Mol Cell Biol (2002) 8.60
Out of Eden: stem cells and their niches. Science (2000) 8.31
Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med (2005) 8.01
The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin. Proc Natl Acad Sci U S A (1999) 7.67
Lgr5 marks cycling, yet long-lived, hair follicle stem cells. Nat Genet (2008) 7.55
A single type of progenitor cell maintains normal epidermis. Nature (2007) 6.32
Modelling Myc inhibition as a cancer therapy. Nature (2008) 5.81
Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34. J Invest Dermatol (2003) 5.28
Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding. Nature (2007) 5.19
Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell (2008) 5.02
A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre-mediated recombination. FEBS Lett (2000) 4.03
Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis. Development (2003) 3.84
NFATc1 balances quiescence and proliferation of skin stem cells. Cell (2008) 3.81
Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. Cell (2006) 3.79
Keratin 15 promoter targets putative epithelial stem cells in the hair follicle bulge. J Invest Dermatol (2003) 3.72
Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol (2004) 3.70
Role of integrins in regulating epidermal adhesion, growth and differentiation. EMBO J (2002) 3.44
Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours. Development (2004) 3.24
c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny. Curr Biol (2001) 3.22
Enrichment for murine keratinocyte stem cells based on cell surface phenotype. Proc Natl Acad Sci U S A (2000) 3.12
Deregulated expression of c-Myc depletes epidermal stem cells. Nat Genet (2001) 3.00
Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence. Proc Natl Acad Sci U S A (2006) 2.91
Epidermal stem cells arise from the hair follicle after wounding. FASEB J (2007) 2.81
Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells. Dev Cell (2005) 2.71
Contribution of stem cells and differentiated cells to epidermal tumours. Nat Rev Cancer (2003) 2.69
The C8/144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells. J Cell Sci (1998) 2.58
Formation of a functional thymus initiated by a postnatal epithelial progenitor cell. Nature (2006) 2.50
The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7. Mol Endocrinol (2000) 2.37
The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases. J Biol Chem (2004) 2.36
Oligopotent stem cells are distributed throughout the mammalian ocular surface. Nature (2008) 2.24
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation. EMBO J (2004) 2.20
A distinct population of clonogenic and multipotent murine follicular keratinocytes residing in the upper isthmus. J Cell Sci (2008) 2.06
Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis. Development (2006) 2.06
The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells. Development (2006) 2.04
Sic transit gloria: farewell to the epidermal transit amplifying cell? Cell Stem Cell (2007) 1.91
Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia. FEBS Lett (2002) 1.51
Characterization of bipotential epidermal progenitors derived from human sebaceous gland: contrasting roles of c-Myc and beta-catenin. Stem Cells (2008) 1.22
Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for beta-catenin and Notch signalling. Dev Biol (2008) 1.19
The multifaceted adult epidermal stem cell. Curr Opin Cell Biol (2003) 1.14
Regenerative biology: new hair from healing wounds. Nature (2007) 1.11
Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles. J Invest Dermatol (2006) 1.00
Thermolysin treatment: a new method for dermo-epidermal separation. J Invest Dermatol (1989) 1.00
Autophagy mediates the mitotic senescence transition. Genes Dev (2009) 6.80
Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model. Nat Med (2004) 3.96
Extracellular-matrix tethering regulates stem-cell fate. Nat Mater (2012) 3.94
Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis. Development (2003) 3.84
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell (2013) 3.47
Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions. Nat Cell Biol (2010) 3.33
Stem cell depletion through epidermal deletion of Rac1. Science (2005) 3.26
Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours. Development (2004) 3.24
Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence. Proc Natl Acad Sci U S A (2006) 2.91
Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis. Development (2009) 2.82
Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development (2002) 2.79
Pax7 and myogenic progression in skeletal muscle satellite cells. J Cell Sci (2006) 2.77
Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells. Dev Cell (2005) 2.71
Contribution of stem cells and differentiated cells to epidermal tumours. Nat Rev Cancer (2003) 2.69
Lineage tracing. Cell (2012) 2.67
Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nat Cell Biol (2012) 2.51
Stem cells are dispensable for lung homeostasis but restore airways after injury. Proc Natl Acad Sci U S A (2009) 2.28
Epithelial stem cells, wound healing and cancer. Nat Rev Cancer (2012) 2.23
Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment. Development (2003) 2.23
Randomized, controlled trial of written emotional expression and benefit finding in breast cancer patients. J Clin Oncol (2002) 2.18
Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis. Development (2006) 2.06
The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells. Development (2006) 2.04
A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair. Development (2002) 2.04
Clinical significance of dermoscopy in alopecia areata: analysis of 300 cases. Int J Dermatol (2008) 1.91
Sic transit gloria: farewell to the epidermal transit amplifying cell? Cell Stem Cell (2007) 1.91
The basement membrane of hair follicle stem cells is a muscle cell niche. Cell (2011) 1.88
Analysis of CLIP and iCLIP methods for nucleotide-resolution studies of protein-RNA interactions. Genome Biol (2012) 1.85
Defining dermal adipose tissue. Exp Dermatol (2014) 1.84
Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFkappaB and cooperating with Stat3. Nat Cell Biol (2008) 1.79
MYC in mammalian epidermis: how can an oncogene stimulate differentiation? Nat Rev Cancer (2008) 1.78
RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis. Nat Struct Mol Biol (2012) 1.75
Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation. Cancer Res (2003) 1.75
New roles for integrins in squamous-cell carcinoma. Nat Rev Cancer (2006) 1.75
Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis. Nat Protoc (2010) 1.72
Hair follicle dermal papilla cells at a glance. J Cell Sci (2011) 1.72
The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors. Curr Biol (2006) 1.71
Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1. J Cell Biol (2006) 1.65
Designer skin: lineage commitment in postnatal epidermis. Trends Cell Biol (2002) 1.59
Mesenchymal-epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiation. J Cell Biol (2004) 1.56
Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway. Curr Biol (2003) 1.54
The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis. PLoS One (2008) 1.53
Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs. Nat Genet (2005) 1.51
Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia. FEBS Lett (2002) 1.51
The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability. J Cell Biol (2009) 1.49
The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate. PLoS Genet (2011) 1.48
NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs. Cell Rep (2013) 1.48
Regulation of human epidermal stem cell proliferation and senescence requires polycomb- dependent and -independent functions of Cbx4. Cell Stem Cell (2011) 1.45
Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation. PLoS One (2007) 1.45
Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin. Development (2011) 1.43
Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human interfollicular epidermis. Development (2003) 1.42
Hair cycle control by leptin as a new anagen inducer. Exp Dermatol (2014) 1.41
Human sebaceous tumors harbor inactivating mutations in LEF1. Nat Med (2006) 1.40
LRIG-1 provides a novel prognostic predictor in squamous cell carcinoma of the skin: immunohistochemical analysis for 38 cases. Dermatol Surg (2005) 1.38
Suprabasal alpha6beta4 integrin expression in epidermis results in enhanced tumourigenesis and disruption of TGFbeta signalling. J Cell Sci (2003) 1.37
Regulation of keratinocyte shape, migration and wound epithelialization by IGF-1- and EGF-dependent signalling pathways. J Cell Sci (2003) 1.37
Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities. J Cell Biol (2003) 1.36
Whole exome sequencing identifies a splicing mutation in NSUN2 as a cause of a Dubowitz-like syndrome. J Med Genet (2012) 1.32
Epidermal stem cells are retained in vivo throughout skin aging. Aging Cell (2008) 1.31
Nevus lipomatosus cutaneous superficialis of the clitoris. Dermatol Surg (2003) 1.31
Clonal growth of dermal papilla cells in hydrogels reveals intrinsic differences between Sox2-positive and -negative cells in vitro and in vivo. J Invest Dermatol (2011) 1.30
Switch from alphavbeta5 to alphavbeta6 integrin expression protects squamous cell carcinomas from anoikis. J Cell Biol (2004) 1.30
Diverse epigenetic strategies interact to control epidermal differentiation. Nat Cell Biol (2012) 1.29
Expression of activated MEK1 in differentiating epidermal cells is sufficient to generate hyperproliferative and inflammatory skin lesions. J Invest Dermatol (2004) 1.27
Alteration of the 4-sphingenine scaffolds of ceramides in keratinocyte-specific Arnt-deficient mice affects skin barrier function. J Clin Invest (2003) 1.26
Signal transducer and activator of transcription 3 is a key regulator of keratinocyte survival and proliferation following UV irradiation. Cancer Res (2005) 1.24
Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that promotes terminal differentiation: contrasting roles of FOXN1 and Akt. J Cell Sci (2004) 1.22
Mutation in NSUN2, which encodes an RNA methyltransferase, causes autosomal-recessive intellectual disability. Am J Hum Genet (2012) 1.22
Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate. Proc Natl Acad Sci U S A (2010) 1.22
Characterization of bipotential epidermal progenitors derived from human sebaceous gland: contrasting roles of c-Myc and beta-catenin. Stem Cells (2008) 1.22
Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier. J Cell Biol (2007) 1.22
Androgen-inducible TGF-beta1 from balding dermal papilla cells inhibits epithelial cell growth: a clue to understand paradoxical effects of androgen on human hair growth. FASEB J (2002) 1.21
What is the point of large-scale collections of human induced pluripotent stem cells? Nat Biotechnol (2013) 1.20
Epidermal label-retaining cells: background and recent applications. J Investig Dermatol Symp Proc (2004) 1.20
The interfollicular epidermis of adult mouse tail comprises two distinct cell lineages that are differentially regulated by Wnt, Edaradd, and Lrig1. Stem Cell Reports (2013) 1.20
Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for beta-catenin and Notch signalling. Dev Biol (2008) 1.19
Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis. Cancer Res (2008) 1.19
A tumor-associated beta 1 integrin mutation that abrogates epithelial differentiation control. J Cell Biol (2003) 1.18
STAT3 deficiency in keratinocytes leads to compromised cell migration through hyperphosphorylation of p130(cas). J Biol Chem (2002) 1.16
Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice. J Clin Invest (2012) 1.16
A year in the life of eLife. Elife (2013) 1.14
Role of LIM kinases in normal and psoriatic human epidermis. Mol Biol Cell (2006) 1.14
Induction of T-cell-mediated skin disease specific for antigen transgenically expressed in keratinocytes. Eur J Immunol (2003) 1.14
Continuous separation of cells by balanced dielectrophoretic forces at multiple frequencies. Lab Chip (2007) 1.14
The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin. EMBO J (2011) 1.11
Characterizing 5-methylcytosine in the mammalian epitranscriptome. Genome Biol (2013) 1.11
Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis. J Invest Dermatol (2007) 1.11
Androgen actions on the human hair follicle: perspectives. Exp Dermatol (2012) 1.09
Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type. Cancer Res (2007) 1.09
The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation. Mol Cell Biol (2013) 1.08
Syntenin mediates Delta1-induced cohesiveness of epidermal stem cells in culture. J Cell Sci (2007) 1.08
The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis. Nat Cell Biol (2011) 1.07