PLCgamma is enriched on poly-phosphoinositide-rich vesicles to control nuclear envelope assembly.

PubWeight™: 0.96‹?› | Rank: Top 15%

🔗 View Article (PMID 17184973)

Published in Cell Signal on November 11, 2006

Authors

Richard D Byrne1, Marie Garnier-Lhomme, Kevin Han, Michael Dowicki, Nick Michael, Nick Totty, Vanessa Zhendre, Aeri Cho, Trevor R Pettitt, Michael J Wakelam, Dominic L Poccia, Banafshé Larijani

Author Affiliations

1: Cell Biophysics Laboratory, Cancer Research UK (CRUK), London Research Institute, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK.

Articles by these authors

Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry. Proteomics (2004) 2.43

Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo. PLoS Biol (2007) 2.28

HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer. PLoS Biol (2010) 2.24

Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect. Proteomics (2003) 2.17

Role of a novel PH-kinase domain interface in PKB/Akt regulation: structural mechanism for allosteric inhibition. PLoS Biol (2009) 2.15

Association between Agent Orange exposure and nonmelanotic invasive skin cancer: a pilot study. Plast Reconstr Surg (2014) 1.97

Monitoring conformational changes of proteins in cells by fluorescence lifetime imaging microscopy. Biochem J (2003) 1.89

The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily. Biochem J (2008) 1.74

RhoE function is regulated by ROCK I-mediated phosphorylation. EMBO J (2005) 1.59

Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection. Mol Cell Biol (2008) 1.41

HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells. PLoS One (2008) 1.31

Mechanism of Trypanosoma brucei gambiense resistance to human serum. Nature (2013) 1.28

Prognostic value of an activation state marker for epidermal growth factor receptor in tissue microarrays of head and neck cancer. Cancer Res (2006) 1.12

Proteomic analysis of primary cell lines identifies protein changes present in renal cell carcinoma. Proteomics (2006) 1.10

Laser capture microdissection and two-dimensional polyacrylamide gel electrophoresis: evaluation of tissue preparation and sample limitations. Am J Pathol (2002) 1.10

PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha. J Clin Invest (2010) 1.09

Breast cancer cell-derived EMMPRIN stimulates fibroblast MMP2 release through a phospholipase A(2) and 5-lipoxygenase catalyzed pathway. Oncogene (2002) 1.08

TAPAS-1, a novel microdomain within the unique N-terminal region of the PDE4A1 cAMP-specific phosphodiesterase that allows rapid, Ca2+-triggered membrane association with selectivity for interaction with phosphatidic acid. J Biol Chem (2002) 1.07

Phosphatidylinositol metabolism and membrane fusion. Biochem J (2009) 1.06

3-D structure and dynamics of protein kinase B-new mechanism for the allosteric regulation of an AGC kinase. J Chem Biol (2009) 1.05

Diacylglycerol induces fusion of nuclear envelope membrane precursor vesicles. J Biol Chem (2005) 1.04

Phospholipase D activity is essential for actin localization and actin-based motility in Dictyostelium. Biochem J (2005) 1.03

Spatially specific expression of Hoxb4 is dependent on the ubiquitous transcription factor NFY. Development (2002) 1.03

Generation of diacylglycerol molecular species through the cell cycle: a role for 1-stearoyl, 2-arachidonyl glycerol in the activation of nuclear protein kinase C-betaII at G2/M. J Cell Sci (2002) 1.02

Stable adhesion and migration of human neutrophils requires phospholipase D-mediated activation of the integrin CD11b/CD18. Mol Immunol (2007) 1.00

Nuclear envelope remnants: fluid membranes enriched in sterols and polyphosphoinositides. PLoS One (2009) 0.99

Regulation of 3-phosphoinositide-dependent protein kinase 1 activity by homodimerization in live cells. Sci Signal (2010) 0.99

Acute manipulation of diacylglycerol reveals roles in nuclear envelope assembly & endoplasmic reticulum morphology. PLoS One (2012) 0.98

Detecting protein-phospholipid interactions. Epidermal growth factor-induced activation of phospholipase D1b in situ. J Biol Chem (2002) 0.97

Phospholipase D2 stimulates integrin-mediated adhesion via phosphatidylinositol 4-phosphate 5-kinase Igamma b. J Cell Sci (2005) 0.96

Approaches to define antigen receptor-induced serine kinase signal transduction pathways. J Biol Chem (2003) 0.95

Novel phosphorylation site markers of protein kinase C delta activation. FEBS Lett (2007) 0.92

Involvement of heterogeneous ribonucleoprotein F in the regulation of cell proliferation via the mammalian target of rapamycin/S6 kinase 2 pathway. J Biol Chem (2010) 0.92

Spatial regulation of membrane fusion controlled by modification of phosphoinositides. PLoS One (2010) 0.92

Proteomic identification of a role for the von Hippel Lindau tumour suppressor in changes in the expression of mitochondrial proteins and septin 2 in renal cell carcinoma. Proteomics (2006) 0.92

Antineutrophil cytoplasm antibody-stimulated neutrophil adhesion depends on diacylglycerol kinase-catalyzed phosphatidic acid formation. J Am Soc Nephrol (2007) 0.90

Revealing signaling in single cells by single- and two-photon fluorescence lifetime imaging microscopy. Methods Mol Biol (2009) 0.89

Lipidomic analysis of signaling pathways. Methods Enzymol (2007) 0.89

Psidin, a conserved protein that regulates protrusion dynamics and cell migration. Genes Dev (2011) 0.89

Nuclear envelope formation: mind the gaps. Annu Rev Biophys (2009) 0.88

Mammal-restricted elements predispose human RET to folding impairment by HSCR mutations. Nat Struct Mol Biol (2010) 0.87

Nuclear envelope assembly is promoted by phosphoinositide-specific phospholipase C with selective recruitment of phosphatidylinositol-enriched membranes. Biochem J (2005) 0.87

Labeling and identification of LNCaP cell surface proteins: a pilot study. Prostate (2007) 0.85

Probing the dynamics of intact cells and nuclear envelope precursor membrane vesicles by deuterium solid state NMR spectroscopy. Biochim Biophys Acta (2007) 0.84

Nuclear envelope formation in vitro: a sea urchin egg cell-free system. Methods Mol Biol (2009) 0.84

Acute regulation of PDK1 by a complex interplay of molecular switches. Biochem Soc Trans (2014) 0.83

Differential activation of the PI 3-kinase effectors AKT/PKB and p70 S6 kinase by compound 48/80 is mediated by PKCalpha. Cell Signal (2006) 0.83

The von Hippel-Lindau tumour-suppressor protein interaction with protein kinase Cdelta. Biochem J (2006) 0.82

Tyrosine kinase regulation of nuclear envelope assembly. Adv Enzyme Regul (2009) 0.82

Identification of pro-interleukin 16 as a novel target of MAP kinases in activated T lymphocytes. Eur J Immunol (2004) 0.82

Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene. Blood (2009) 0.81

Key role of polyphosphoinositides in dynamics of fusogenic nuclear membrane vesicles. PLoS One (2011) 0.81

Androgen receptor is targeted to distinct subcellular compartments in response to different therapeutic antiandrogens. Clin Cancer Res (2004) 0.81

Dynamics of PLCγ and Src family kinase 1 interactions during nuclear envelope formation revealed by FRET-FLIM. PLoS One (2012) 0.80

Site recognition and substrate screens for PKN family proteins. Biochem J (2011) 0.80

The PH domain of phosphoinositide-dependent kinase-1 exhibits a novel, phospho-regulated monomer-dimer equilibrium with important implications for kinase domain activation: single-molecule and ensemble studies. Biochemistry (2013) 0.80

Accumulated bending energy elicits neutral sphingomyelinase activity in human red blood cells. Biophys J (2012) 0.79

Role of the C-terminal regulatory domain in the allosteric inhibition of PKB/Akt. Adv Biol Regul (2012) 0.78

Effects of phosphoinositides and their derivatives on membrane morphology and function. Curr Top Microbiol Immunol (2012) 0.78

Lipid quantification and structure determination of nuclear envelope precursor membranes in the sea urchin. Methods Mol Biol (2009) 0.78

Liquid refractive index sensing independent of opacity using an optofluidic diffraction sensor. Opt Lett (2014) 0.78

An intracellular motif of GLUT4 regulates fusion of GLUT4-containing vesicles. BMC Cell Biol (2008) 0.77

Restricted state selection in fluorescent protein Förster resonance energy transfer. J Am Chem Soc (2013) 0.77

Rubber particle proteins, HbREF and HbSRPP, show different interactions with model membranes. Biochim Biophys Acta (2013) 0.77

Large-area, uniform and low-cost dual-mode plasmonic naked-eye colorimetry and SERS sensor with handheld Raman spectrometer. Nanoscale (2016) 0.76

Identification of proteins regulated by interferon-alpha in resistant and sensitive malignant melanoma cell lines. Proteomics (2004) 0.76

Assays to study phospholipase D regulation by inositol phospholipids and ADP-ribosylation factor 6. Methods Enzymol (2005) 0.76

A dual role for diacylglycerol kinase generated phosphatidic acid in autoantibody-induced neutrophil exocytosis. Mol Med (2011) 0.76

Conservation of proteo-lipid nuclear membrane fusion machinery during early embryogenesis. Nucleus (2014) 0.75

Functional proteomic analysis of long-term growth factor stimulation and receptor tyrosine kinase coactivation in Swiss 3T3 fibroblasts. Mol Cell Proteomics (2012) 0.75

Acute depletion of plasma membrane phospholipids-dissecting the roles of PtdIns(4)P and PtdIns(4,5)P2. J Chem Biol (2012) 0.75

Correction: HER2 Phosphorylation Is Maintained by a PKB Negative Feedback Loop in Response to Anti-HER2 Herceptin in Breast Cancer. PLoS Biol (2016) 0.75

A structural role for lipids in organelle shaping. Biol Bull (2013) 0.75

Protein activation dynamics in cells and tumor micro arrays assessed by time resolved Förster resonance energy transfer. Methods Enzymol (2012) 0.75

Aminosilane/oleic acid vesicles as model membranes of protocells. Langmuir (2014) 0.75

Determination of phospholipase D, lysophospholipase D and DG kinase signaling pathways in disease states by mass spectrometry. Adv Enzyme Regul (2008) 0.75

Localised interventions in cellular processes. Biochim Biophys Acta (2013) 0.75

Elastomeric 2D grating and hemispherical optofluidic chamber for multifunctional fluidic sensing. J Opt Soc Am A Opt Image Sci Vis (2013) 0.75