Published in Proteomics on December 01, 2004
Membrane vesicles as conveyors of immune responses. Nat Rev Immunol (2009) 14.72
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature (2015) 5.15
Exosome function: from tumor immunology to pathogen biology. Traffic (2008) 4.50
Microenvironmental pH is a key factor for exosome traffic in tumor cells. J Biol Chem (2009) 2.99
Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling. J Cell Biol (2010) 2.85
Induction of myeloid-derived suppressor cells by tumor exosomes. Int J Cancer (2009) 2.64
Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells. Mol Cancer (2011) 2.56
Down-regulation of miR-92 in human plasma is a novel marker for acute leukemia patients. PLoS One (2009) 2.55
Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review. Cancer Metastasis Rev (2013) 2.46
Extracellular vesicles produced by Cryptococcus neoformans contain protein components associated with virulence. Eukaryot Cell (2007) 2.42
BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. J Clin Invest (2013) 2.34
Characterization of human plasma-derived exosomal RNAs by deep sequencing. BMC Genomics (2013) 2.27
Exosomes in tumor microenvironment influence cancer progression and metastasis. J Mol Med (Berl) (2013) 2.12
Proteomic and immunologic analyses of brain tumor exosomes. FASEB J (2008) 2.11
Microvesicles and viral infection. J Virol (2011) 2.10
Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature. Mol Cell Proteomics (2009) 2.08
Proteomics analysis of bladder cancer exosomes. Mol Cell Proteomics (2010) 2.04
Astrocytes and Glioblastoma cells release exosomes carrying mtDNA. J Neural Transm (Vienna) (2009) 1.97
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J Proteome Res (2009) 1.97
Exosomes released from infected macrophages contain Mycobacterium avium glycopeptidolipids and are proinflammatory. J Biol Chem (2007) 1.96
Cellular proteins in influenza virus particles. PLoS Pathog (2008) 1.96
Exosomal transfer of proteins and RNAs at synapses in the nervous system. Biol Direct (2007) 1.93
Tumor-derived microvesicles promote regulatory T cell expansion and induce apoptosis in tumor-reactive activated CD8+ T lymphocytes. J Immunol (2009) 1.79
DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer. Oncogene (2011) 1.76
Paracrine induction of endothelium by tumor exosomes. Lab Invest (2009) 1.63
Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes. Nucleic Acids Res (2012) 1.60
Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. J Extracell Vesicles (2012) 1.52
Secretion of extracellular hsp90alpha via exosomes increases cancer cell motility: a role for plasminogen activation. BMC Cancer (2010) 1.51
Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One (2012) 1.43
Cell-free Circulating miRNA Biomarkers in Cancer. J Cancer (2012) 1.37
Exosomes and the kidney: prospects for diagnosis and therapy of renal diseases. Kidney Int (2011) 1.37
Myeloma as a model for the process of metastasis: implications for therapy. Blood (2012) 1.36
Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages. Infect Immun (2009) 1.34
Mechanisms of cellular communication through intercellular protein transfer. J Cell Mol Med (2010) 1.32
Role of exosomes in immune regulation. J Cell Mol Med (2006) 1.29
Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Mol Cell Proteomics (2012) 1.26
Characterization of yeast extracellular vesicles: evidence for the participation of different pathways of cellular traffic in vesicle biogenesis. PLoS One (2010) 1.24
Horizontal transfer of RNAs: exosomes as mediators of intercellular communication. Wiley Interdiscip Rev RNA (2011) 1.23
Stem cell plasticity revisited: the continuum marrow model and phenotypic changes mediated by microvesicles. Exp Hematol (2010) 1.22
Whole tumor antigen vaccines. Semin Immunol (2010) 1.19
Annexin A2 heterotetramer: structure and function. Int J Mol Sci (2013) 1.17
Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. J Extracell Vesicles (2012) 1.16
Circulating miR-150 and miR-342 in plasma are novel potential biomarkers for acute myeloid leukemia. J Transl Med (2013) 1.11
Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3. Mol Cell Proteomics (2012) 1.08
Comparative marker analysis of extracellular vesicles in different human cancer types. J Extracell Vesicles (2013) 1.06
Biogenesis of the posterior pole is mediated by the exosome/microvesicle protein-sorting pathway. J Biol Chem (2011) 1.05
Comparative Bioinformatics Analyses and Profiling of Lysosome-Related Organelle Proteomes. Int J Mass Spectrom (2007) 1.04
Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression. PLoS One (2013) 1.02
Exploration of microRNAs in porcine milk exosomes. BMC Genomics (2014) 1.01
Identification of host proteins associated with retroviral vector particles by proteomic analysis of highly purified vector preparations. J Virol (2007) 1.01
Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods. PLoS One (2015) 1.00
Tumor-derived exosomes: A message delivery system for tumor progression. Commun Integr Biol (2014) 0.99
Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting. J Extracell Vesicles (2015) 0.98
A new role for microRNAs, as ligands of Toll-like receptors. RNA Biol (2013) 0.96
MicroRNA and protein profiling of brain metastasis competent cell-derived exosomes. PLoS One (2013) 0.94
Activated human T cells secrete exosomes that participate in IL-2 mediated immune response signaling. PLoS One (2012) 0.93
Biogenesis of extracellular vesicles in yeast: Many questions with few answers. Commun Integr Biol (2010) 0.90
Characterization of multiple myeloma vesicles by label-free relative quantitation. Proteomics (2013) 0.89
Exosomes: an overview of biogenesis, composition and role in ovarian cancer. J Ovarian Res (2014) 0.88
Evolution of organelle-associated protein profiling. J Proteomics (2008) 0.87
Whole Tumor Antigen Vaccines: Where Are We? Vaccines (Basel) (2015) 0.87
Surface-modified HK:siRNA nanoplexes with enhanced pharmacokinetics and tumor growth inhibition. Biomacromolecules (2013) 0.86
Three are better than one: plasminogen receptors as cancer theranostic targets. Exp Hematol Oncol (2013) 0.84
The potential of tumor-derived exosomes for noninvasive cancer monitoring. Expert Rev Mol Diagn (2015) 0.81
Lung cancer exosomes as drivers of epithelial mesenchymal transition. Oncotarget (2016) 0.81
MicroRNAs in extracellular vesicles: potential cancer biomarkers. J Hum Genet (2016) 0.81
Osteoclast-derived microRNA-containing exosomes selectively inhibit osteoblast activity. Cell Discov (2016) 0.80
High-yield isolation of extracellular vesicles using aqueous two-phase system. Sci Rep (2015) 0.80
Exosomes: The Messengers of Health and Disease. Curr Neuropharmacol (2016) 0.80
RIG-I activation induces the release of extracellular vesicles with antitumor activity. Oncoimmunology (2016) 0.79
Exosomes Secreted from Human Cancer Cell Lines Contain Inhibitors of Apoptosis (IAP). Cancer Microenviron (2015) 0.79
The emerging role of exosomes in survivin secretion. Histol Histopathol (2014) 0.79
Cell death in response to antimetabolites directed at ribonucleotide reductase and thymidylate synthase. Onco Targets Ther (2015) 0.78
Bone marrow stromal/stem cell-derived extracellular vesicles regulate osteoblast activity and differentiation in vitro and promote bone regeneration in vivo. Sci Rep (2016) 0.78
Osteoblast-released Matrix Vesicles, Regulation of Activity and Composition by Sulfated and Non-sulfated Glycosaminoglycans. Mol Cell Proteomics (2015) 0.78
Inter-cellular transport of ran GTPase. PLoS One (2015) 0.77
Gamma-enolase: a well-known tumour marker, with a less-known role in cancer. Radiol Oncol (2015) 0.77
Therapeutic potential of CAR-T cell-derived exosomes: a cell-free modality for targeted cancer therapy. Oncotarget (2015) 0.77
Exosome: A Novel Approach to Stimulate Bone Regeneration through Regulation of Osteogenesis and Angiogenesis. Int J Mol Sci (2016) 0.76
Mast Cell-Derived Exosomes Promote Th2 Cell Differentiation via OX40L-OX40 Ligation. J Immunol Res (2016) 0.75
Exosomes derived from embryonal and alveolar rhabdomyosarcoma carry differential miRNA cargo and promote invasion of recipient fibroblasts. Sci Rep (2016) 0.75
Biology, Therapy and Implications of Tumor Exosomes in the Progression of Melanoma. Cancers (Basel) (2016) 0.75
Tumor-derived exosomes induce CD8(+) T cell suppressors. J Immunother Cancer (2017) 0.75
High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med (2003) 8.93
Measuring quality of life in routine oncology practice improves communication and patient well-being: a randomized controlled trial. J Clin Oncol (2004) 5.84
Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. Nat Genet (2010) 2.96
Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer. Cancer Res (2006) 2.87
Clinical proteomics: A need to define the field and to begin to set adequate standards. Proteomics Clin Appl (2007) 2.84
Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway. Neuron (2006) 2.79
Predicting response to bevacizumab in ovarian cancer: a panel of potential biomarkers informing treatment selection. Clin Cancer Res (2013) 2.45
Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG. Glycobiology (2007) 2.45
Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect. Proteomics (2003) 2.17
The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily. Biochem J (2008) 1.74
Structure and chemical inhibition of the RET tyrosine kinase domain. J Biol Chem (2006) 1.72
Housekeeping proteins: a preliminary study illustrating some limitations as useful references in protein expression studies. Proteomics (2005) 1.69
Serum aminoacylase-1 is a novel biomarker with potential prognostic utility for long-term outcome in patients with delayed graft function following renal transplantation. Kidney Int (2013) 1.61
RhoE function is regulated by ROCK I-mediated phosphorylation. EMBO J (2005) 1.59
Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma. Int J Cancer (2005) 1.55
Analysis of VHL Gene Alterations and their Relationship to Clinical Parameters in Sporadic Conventional Renal Cell Carcinoma. Clin Cancer Res (2009) 1.49
Influences of blood sample processing on low-molecular-weight proteome identified by surface-enhanced laser desorption/ionization mass spectrometry. Clin Chem (2005) 1.46
Tumor infection by oncolytic reovirus primes adaptive antitumor immunity. Clin Cancer Res (2008) 1.44
Factor analysis of the Hospital Anxiety and Depression Scale from a large cancer population. Psychol Psychother (2002) 1.40
Development and validation of a novel protein extraction methodology for quantitation of protein expression in formalin-fixed paraffin-embedded tissues using western blotting. J Pathol (2009) 1.38
Dacarbazine, cisplatin, and interferon-alfa-2b with or without interleukin-2 in metastatic melanoma: a randomized phase III trial (18951) of the European Organisation for Research and Treatment of Cancer Melanoma Group. J Clin Oncol (2005) 1.36
CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76. Mol Cell Biol (2006) 1.35
A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23. Hum Mol Genet (2011) 1.34
Role of PPARgamma and EGFR signalling in the urothelial terminal differentiation programme. J Cell Sci (2004) 1.29
Ulceration and stage are predictive of interferon efficacy in melanoma: results of the phase III adjuvant trials EORTC 18952 and EORTC 18991. Eur J Cancer (2011) 1.28
Banking of biological fluids for studies of disease-associated protein biomarkers. Mol Cell Proteomics (2008) 1.27
Tumor suppressor activity and epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma. Cancer Res (2005) 1.27
Proteomic profiling of urinary proteins in renal cancer by surface enhanced laser desorption ionization and neural-network analysis: identification of key issues affecting potential clinical utility. Cancer Res (2003) 1.26
Reciprocal human dendritic cell-natural killer cell interactions induce antitumor activity following tumor cell infection by oncolytic reovirus. J Immunol (2009) 1.25
Proteomic profiling identifies afamin as a potential biomarker for ovarian cancer. Clin Cancer Res (2007) 1.25
A Rasch and factor analysis of the Functional Assessment of Cancer Therapy-General (FACT-G). Health Qual Life Outcomes (2007) 1.19
The clinical value of quality of life assessment in oncology practice-a qualitative study of patient and physician views. Psychooncology (2008) 1.18
Mining the archival formalin-fixed paraffin-embedded tissue proteome: opportunities and challenges. Mol Biosyst (2008) 1.18
CD4(+)CD25(+)FoxP3(+) regulatory T cells are increased whilst CD3(+)CD4(-)CD8(-)alphabetaTCR(+) Double Negative T cells are decreased in the peripheral blood of patients with multiple myeloma which correlates with disease burden. Br J Haematol (2008) 1.17
Autocrine regulation of human urothelial cell proliferation and migration during regenerative responses in vitro. Exp Cell Res (2005) 1.13
Urinary biomarker profiling in transitional cell carcinoma. Int J Cancer (2006) 1.12
Internalization of oncolytic reovirus by human dendritic cell carriers protects the virus from neutralization. Clin Cancer Res (2011) 1.12
Autoimmune antibodies and recurrence-free interval in melanoma patients treated with adjuvant interferon. J Natl Cancer Inst (2009) 1.11
Psychosocial care for cancer patients in primary care? Recognition of opportunities for cancer care. Fam Pract (2004) 1.11
Laser capture microdissection and two-dimensional polyacrylamide gel electrophoresis: evaluation of tissue preparation and sample limitations. Am J Pathol (2002) 1.10
Proteomic analysis of primary cell lines identifies protein changes present in renal cell carcinoma. Proteomics (2006) 1.10
Patients report improvements in continuity of care when quality of life assessments are used routinely in oncology practice: secondary outcomes of a randomised controlled trial. Eur J Cancer (2010) 1.09
S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent manner. Genes Dev (2006) 1.09
Impact of patient-reported outcomes in oncology: a longitudinal analysis of patient-physician communication. J Clin Oncol (2011) 1.09
Renal cancer biomarkers: the promise of personalized care. BMC Med (2012) 1.08
Proteomic analysis of formalin-fixed paraffin-embedded renal tissue samples by label-free MS: assessment of overall technical variability and the impact of block age. Proteomics Clin Appl (2013) 1.08
Initial development and validation of a novel extraction method for quantitative mining of the formalin-fixed, paraffin-embedded tissue proteome for biomarker investigations. J Proteome Res (2010) 1.07
Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia. Arthritis Res Ther (2004) 1.04
Banking of clinical samples for proteomic biomarker studies: a consideration of logistical issues with a focus on pre-analytical variation. Proteomics Clin Appl (2010) 1.04
Integrated multi-level quality control for proteomic profiling studies using mass spectrometry. BMC Bioinformatics (2008) 1.04
Spatially specific expression of Hoxb4 is dependent on the ubiquitous transcription factor NFY. Development (2002) 1.03
A systematic analysis of the effects of increasing degrees of serum immunodepletion in terms of depth of coverage and other key aspects in top-down and bottom-up proteomic analyses. Proteomics (2011) 1.02
Identification of novel VHL target genes and relationship to hypoxic response pathways. Oncogene (2005) 1.01
The p53 positive Bcl-2 negative phenotype is an independent marker of prognosis in breast cancer. Int J Cancer (2007) 1.01
Phase III trial comparing adjuvant treatment with pegylated interferon Alfa-2b versus observation: prognostic significance of autoantibodies--EORTC 18991. J Clin Oncol (2010) 1.00
Immune recruitment and therapeutic synergy: keys to optimizing oncolytic viral therapy? Clin Cancer Res (2011) 1.00
Closely related mycobacterial strains demonstrate contrasting levels of efficacy as antitumor vaccines and are processed for major histocompatibility complex class I presentation by multiple routes in dendritic cells. Infect Immun (2005) 0.99
Cross-presentation of epitopes on virus-like particles via the MHC I receptor recycling pathway. Immunol Cell Biol (2011) 0.98
PLCgamma is enriched on poly-phosphoinositide-rich vesicles to control nuclear envelope assembly. Cell Signal (2006) 0.96
Intrinsic chemotherapy resistance to the tubulin-binding antimitotic agents in renal cell carcinoma. Int J Cancer (2005) 0.96
Prognostic factors in renal cell carcinoma: association of preoperative sodium concentration with survival. Clin Cancer Res (2008) 0.96
Approaches to define antigen receptor-induced serine kinase signal transduction pathways. J Biol Chem (2003) 0.95
Tumour cell generation of inducible regulatory T-cells in multiple myeloma is contact-dependent and antigen-presenting cell-independent. PLoS One (2012) 0.95
Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function. Proteomics (2009) 0.94
Use of proteomic methodology for the characterization of human milk fat globular membrane proteins. Anal Biochem (2002) 0.93
Novel phosphorylation site markers of protein kinase C delta activation. FEBS Lett (2007) 0.92
Proteomic identification of a role for the von Hippel Lindau tumour suppressor in changes in the expression of mitochondrial proteins and septin 2 in renal cell carcinoma. Proteomics (2006) 0.92
Involvement of heterogeneous ribonucleoprotein F in the regulation of cell proliferation via the mammalian target of rapamycin/S6 kinase 2 pathway. J Biol Chem (2010) 0.92