Published in Dev Biol on December 12, 2006
Regulation of spermatogonial stem cell self-renewal in mammals. Annu Rev Cell Dev Biol (2008) 2.79
Glial cell line-derived neurotrophic factor regulation of genes essential for self-renewal of mouse spermatogonial stem cells is dependent on Src family kinase signaling. J Biol Chem (2007) 1.98
The germline stem cell niche unit in mammalian testes. Physiol Rev (2012) 1.86
Spermatogonial stem cell regulation and spermatogenesis. Philos Trans R Soc Lond B Biol Sci (2010) 1.76
Colony stimulating factor 1 is an extrinsic stimulator of mouse spermatogonial stem cell self-renewal. Development (2009) 1.74
Activation of two distinct Sox9-EGFP-expressing intestinal stem cell populations during crypt regeneration after irradiation. Am J Physiol Gastrointest Liver Physiol (2012) 1.67
Gdnf upregulates c-Fos transcription via the Ras/Erk1/2 pathway to promote mouse spermatogonial stem cell proliferation. Stem Cells (2007) 1.61
Germline stem cells. Cold Spring Harb Perspect Biol (2011) 1.53
Yangjing Capsule Extract Promotes Proliferation of GC-1 Spg Cells. Evid Based Complement Alternat Med (2014) 1.41
Prepubertal human spermatogonia and mouse gonocytes share conserved gene expression of germline stem cell regulatory molecules. Proc Natl Acad Sci U S A (2009) 1.34
Gdnf signaling pathways within the mammalian spermatogonial stem cell niche. Mol Cell Endocrinol (2008) 1.32
Silver nanoparticles disrupt GDNF/Fyn kinase signaling in spermatogonial stem cells. Toxicol Sci (2010) 1.31
Nodal signaling via an autocrine pathway promotes proliferation of mouse spermatogonial stem/progenitor cells through Smad2/3 and Oct-4 activation. Stem Cells (2009) 1.15
Phenotypic plasticity of mouse spermatogonial stem cells. PLoS One (2009) 1.11
Spermatogonial stem cells, infertility and testicular cancer. J Cell Mol Med (2011) 1.09
The Syk kinase SmTK4 of Schistosoma mansoni is involved in the regulation of spermatogenesis and oogenesis. PLoS Pathog (2010) 1.08
Spermatogonial stem cell self-renewal requires ETV5-mediated downstream activation of Brachyury in mice. Biol Reprod (2011) 1.07
Loss of Etv5 decreases proliferation and RET levels in neonatal mouse testicular germ cells and causes an abnormal first wave of spermatogenesis. Biol Reprod (2009) 1.05
Testicular cancer and cryptorchidism. Front Endocrinol (Lausanne) (2013) 1.03
Human spermatogonial stem cells: a possible origin for spermatocytic seminoma. Int J Androl (2011) 1.01
Spermatogonial culture medium: an effective and efficient nutrient mixture for culturing rat spermatogonial stem cells. Biol Reprod (2009) 1.00
Bone marrow stromal cells protect oligodendrocytes from oxygen-glucose deprivation injury. J Neurosci Res (2008) 0.97
Claudin 5 expression in mouse seminiferous epithelium is dependent upon the transcription factor ets variant 5 and contributes to blood-testis barrier function. Biol Reprod (2009) 0.96
Skp1-Cullin-F-box (SCF)-type ubiquitin ligase FBXW7 negatively regulates spermatogonial stem cell self-renewal. Proc Natl Acad Sci U S A (2014) 0.95
Expression of Mirlet7 family microRNAs in response to retinoic acid-induced spermatogonial differentiation in mice. Biol Reprod (2011) 0.95
In vivo and in vitro aging is detrimental to mouse spermatogonial stem cell function. Biol Reprod (2010) 0.94
Cyclical and patch-like GDNF distribution along the basal surface of Sertoli cells in mouse and hamster testes. PLoS One (2011) 0.91
C-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics. Adv Exp Med Biol (2012) 0.88
Cross-talk between the Akt and NF-kappaB signaling pathways inhibits MEHP-induced germ cell apoptosis. Toxicol Sci (2008) 0.87
Signaling pathways in spermatogonial stem cells and their disruption by toxicants. Birth Defects Res C Embryo Today (2009) 0.86
Regulation of the spermatogonial stem cell niche. Reprod Domest Anim (2008) 0.85
Mono-(2-ethylhexyl)-phthalate (MEHP) affects ERK-dependent GDNF signalling in mouse stem-progenitor spermatogonia. Toxicology (2012) 0.84
Gene expression profiling of rat spermatogonia and Sertoli cells reveals signaling pathways from stem cells to niche and testicular cancer cells to surrounding stroma. BMC Genomics (2011) 0.83
Epigenetic modifications and self-renewal regulation of mouse germline stem cells. Cell Res (2011) 0.83
Significance of microRNA targeted estrogen receptor in male fertility. Iran J Basic Med Sci (2014) 0.81
Anchoring ethinylestradiol induced gene expression changes with testicular morphology and reproductive function in the medaka. PLoS One (2012) 0.79
Three-dimensional synthetic niche components to control germ cell proliferation. Tissue Eng Part A (2009) 0.79
Characterization and in vitro culture of putative spermatogonial stem cells derived from feline testicular tissue. J Reprod Dev (2013) 0.78
Identification and characterization of a novel testis-specific gene CKT2, which encodes a substrate for protein kinase CK2. Nucleic Acids Res (2009) 0.77
Signaling molecules and pathways regulating the fate of spermatogonial stem cells. Microsc Res Tech (2009) 0.77
Unveiling MYCN regulatory networks in neuroblastoma via integrative analysis of heterogeneous genomics data. Oncotarget (2016) 0.76
Extrinsic and intrinsic factors controlling spermatogonial stem cell self-renewal and differentiation. Asian J Androl (2015) 0.76
TAF4b is required for mouse spermatogonial stem cell development. Stem Cells (2015) 0.76
Regulation of germ line stem cell homeostasis. Anim Reprod (2017) 0.75
Thyroid C-Cell Biology and Oncogenic Transformation. Recent Results Cancer Res (2015) 0.75
The interaction between Sertoli cells and luekemia inhibitory factor on the propagation and differentiation of spermatogonial stem cells in vitro. Iran J Reprod Med (2015) 0.75
Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science (1997) 11.48
Cellular functions regulated by Src family kinases. Annu Rev Cell Dev Biol (1997) 11.36
Spermatogenic cells of the prepuberal mouse. Isolation and morphological characterization. J Cell Biol (1977) 7.69
The GDNF family: signalling, biological functions and therapeutic value. Nat Rev Neurosci (2002) 5.93
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development (2005) 5.80
Regulation of cell fate decision of undifferentiated spermatogonia by GDNF. Science (2000) 5.44
Long-term proliferation in culture and germline transmission of mouse male germline stem cells. Biol Reprod (2003) 5.32
A niche maintaining germ line stem cells in the Drosophila ovary. Science (2000) 5.04
Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells. Proc Natl Acad Sci U S A (2004) 4.77
piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells. Development (2000) 4.54
Pluripotency of spermatogonial stem cells from adult mouse testis. Nature (2006) 4.29
Repression of p15INK4b expression by Myc through association with Miz-1. Nat Cell Biol (2001) 4.22
Generation of pluripotent stem cells from neonatal mouse testis. Cell (2004) 3.95
All you wanted to know about spermatogonia but were afraid to ask. J Androl (2001) 3.80
Deconstructing myc. Genes Dev (2001) 3.30
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis. Proc Natl Acad Sci U S A (2001) 3.29
Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev (2001) 3.15
Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice. Dev Biol (1994) 3.07
Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors. Proc Natl Acad Sci U S A (2003) 2.72
Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation. Development (2005) 2.64
Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors. Development (2003) 2.42
Isolation of male germ-line stem cells; influence of GDNF. Dev Biol (2005) 2.40
Glial cell-line derived neurotrophic factor-mediated RET signaling regulates spermatogonial stem cell fate. Biol Reprod (2005) 2.35
Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation. Mech Dev (1998) 2.28
Gonadal expression of c-kit encoded at the W locus of the mouse. Development (1990) 2.21
Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis. Dev Biol (2004) 2.13
Long-term culture of mouse male germline stem cells under serum-or feeder-free conditions. Biol Reprod (2004) 2.01
Roles for c-Myc in self-renewal of hematopoietic stem cells. J Biol Chem (2004) 1.95
Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J Cell Biol (1995) 1.73
Expression of N-myc in teratocarcinoma stem cells and mouse embryos. Nature (1985) 1.72
GDNF family receptor alpha1 phenotype of spermatogonial stem cells in immature mouse testes. Biol Reprod (2005) 1.71
Expression of neurturin, GDNF, and GDNF family-receptor mRNA in the developing and mature mouse. Exp Neurol (1999) 1.67
DAZ family proteins exist throughout male germ cell development and transit from nucleus to cytoplasm at meiosis in humans and mice. Biol Reprod (2000) 1.64
GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival. Neuron (2000) 1.56
Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase. J Biol Chem (2000) 1.52
Ureteric bud outgrowth in response to RET activation is mediated by phosphatidylinositol 3-kinase. Dev Biol (2002) 1.45
Endogenous Myc controls mammalian epidermal cell size, hyperproliferation, endoreplication and stem cell amplification. J Cell Sci (2005) 1.40
Expression of c-kit receptor and its autophosphorylation in immature rat type A spermatogonia. Biol Reprod (1995) 1.35
The Src family of tyrosine kinases is important for embryonic stem cell self-renewal. J Biol Chem (2004) 1.31
Stem cell protein Piwil2 modulates expression of murine spermatogonial stem cell expressed genes. Mol Reprod Dev (2006) 1.31
Immortalization of mouse germ line stem cells. Stem Cells (2005) 1.25
The emerging phenotype of the testicular carcinoma in situ germ cell. APMIS (2003) 1.24
c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway. J Neurosci (2001) 1.19
Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase. J Cell Sci (1996) 1.18
Lipid rafts and the control of neurotrophic factor signaling in the nervous system: variations on a theme. Curr Opin Neurobiol (2002) 1.12
Clinical implications of PRAME gene expression in childhood acute myeloid leukemia. Cancer Genet Cytogenet (2002) 1.12
Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival. J Biol Chem (2004) 1.11
Notch-1, c-kit and GFRalpha-1 are developmentally regulated markers for premeiotic germ cells. Cytogenet Genome Res (2004) 1.06
Expression of Notch pathway components in spermatogonia and Sertoli cells of neonatal mice. J Androl (2001) 1.05
Promotion of seminomatous tumors by targeted overexpression of glial cell line-derived neurotrophic factor in mouse testis. Cancer Res (2001) 1.05
The niche for spermatogonial stem cells in the mammalian testis. Int J Hematol (2005) 1.01
Morphological characterization of the spermatogonial subtypes in the neonatal mouse testis. Biol Reprod (2003) 0.97
Glial cell line-derived neutrotrophic factor and neurturin can act as paracrine growth factors stimulating DNA synthesis of Ret-expressing spermatogonia. Int J Oncol (2000) 0.97
Src: regulation, role in human carcinogenesis and pharmacological inhibitors. Curr Pharm Des (2004) 0.91
Ret-mediated mitogenesis requires Src kinase activity. Cancer Res (1999) 0.90
Oncogene expression in small-cell lung cancer cell lines and a testicular germ-cell tumor: activation of the N-myc gene and decreased RB mRNA. Int J Cancer (1989) 0.81
Differential expression of protooncogenes in human germ cell tumors of the testis. Cancer (1994) 0.80
pp60c-src expression in rat spermatogenesis. Biochem Biophys Res Commun (1995) 0.78
Postnatal changes in the expression of p60c-Src in mouse testes. Dev Growth Differ (2005) 0.77
In vitro cytotoxicity of nanoparticles in mammalian germline stem cells. Toxicol Sci (2005) 2.89
ERM is required for transcriptional control of the spermatogonial stem cell niche. Nature (2005) 2.58
Isolation of male germ-line stem cells; influence of GDNF. Dev Biol (2005) 2.40
Cellular source and mechanisms of high transcriptome complexity in the mammalian testis. Cell Rep (2013) 1.79
Pluripotent stem cells derived from adult human testes. Stem Cells Dev (2009) 1.71
Isolation, characterization, and culture of human spermatogonia. Biol Reprod (2009) 1.64
Gdnf upregulates c-Fos transcription via the Ras/Erk1/2 pathway to promote mouse spermatogonial stem cell proliferation. Stem Cells (2007) 1.61
Generation and in vitro differentiation of a spermatogonial cell line. Science (2002) 1.53
Gfra1 silencing in mouse spermatogonial stem cells results in their differentiation via the inactivation of RET tyrosine kinase. Biol Reprod (2007) 1.36
Silver nanoparticles disrupt GDNF/Fyn kinase signaling in spermatogonial stem cells. Toxicol Sci (2010) 1.31
Small RNA molecules in the regulation of spermatogenesis. Reproduction (2009) 1.26
Analysis of mouse germ-cell transcriptome at different stages of spermatogenesis by SAGE: biological significance. Genomics (2004) 1.20
Oocyte-like cells induced from mouse spermatogonial stem cells. Cell Biosci (2012) 1.16
Nodal signaling via an autocrine pathway promotes proliferation of mouse spermatogonial stem/progenitor cells through Smad2/3 and Oct-4 activation. Stem Cells (2009) 1.15
Mechanistic insights into the regulation of the spermatogonial stem cell niche. Cell Cycle (2006) 1.12
Effects of ETV5 (ets variant gene 5) on testis and body growth, time course of spermatogonial stem cell loss, and fertility in mice. Biol Reprod (2007) 1.12
Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem/progenitor cells. Reproduction (2009) 1.09
The molecular signature of spermatogonial stem/progenitor cells in the 6-day-old mouse testis. Biol Reprod (2008) 1.09
Bone metastases and skeletal-related events in patients with malignant pheochromocytoma and sympathetic paraganglioma. J Clin Endocrinol Metab (2013) 1.08
Loss of Etv5 decreases proliferation and RET levels in neonatal mouse testicular germ cells and causes an abnormal first wave of spermatogenesis. Biol Reprod (2009) 1.05
Expression profiling of purified male germ cells: stage-specific expression patterns related to meiosis and postmeiotic development. Physiol Genomics (2005) 1.02
Direct transdifferentiation of stem/progenitor spermatogonia into reproductive and nonreproductive tissues of all germ layers. Stem Cells (2009) 1.01
MiRNA-20 and mirna-106a regulate spermatogonial stem cell renewal at the post-transcriptional level via targeting STAT3 and Ccnd1. Stem Cells (2013) 0.99
ETV5 regulates sertoli cell chemokines involved in mouse stem/progenitor spermatogonia maintenance. Stem Cells (2010) 0.98
Morphological characterization of the spermatogonial subtypes in the neonatal mouse testis. Biol Reprod (2003) 0.97
Constitutive activation of NOTCH1 signaling in Sertoli cells causes gonocyte exit from quiescence. Dev Biol (2013) 0.94
Expression of testicular germ cell genes identified by differential display analysis. J Androl (2003) 0.94
Role of glial cell line-derived neurotrophic factor in germ-line stem cell fate. Ann N Y Acad Sci (2005) 0.92
ETV5 is required for continuous spermatogenesis in adult mice and may mediate blood testes barrier function and testicular immune privilege. Ann N Y Acad Sci (2007) 0.91
Identification of differentially expressed genes in mouse spermatogenesis. J Androl (2003) 0.91
Expression of Col1a1, Col1a2 and procollagen I in germ cells of immature and adult mouse testis. Reproduction (2005) 0.90
Isolation of undifferentiated and early differentiating type A spermatogonia from Pou5f1-GFP reporter mice. Methods Mol Biol (2012) 0.89
Structural characterization and expression studies of Dby and its homologs in the mouse. J Androl (2006) 0.88
Isolation of human male germ-line stem cells using enzymatic digestion and magnetic-activated cell sorting. Methods Mol Biol (2012) 0.88
Spermatogonial stem cell markers and niche in equids. PLoS One (2012) 0.87
Age affects gene expression in mouse spermatogonial stem/progenitor cells. Reproduction (2010) 0.86
Signaling pathways in spermatogonial stem cells and their disruption by toxicants. Birth Defects Res C Embryo Today (2009) 0.86
Expression of vascular endothelial growth factor receptors during male germ cell differentiation in the mouse. Biol Reprod (2003) 0.85
Mono-(2-ethylhexyl)-phthalate (MEHP) affects ERK-dependent GDNF signalling in mouse stem-progenitor spermatogonia. Toxicology (2012) 0.84
Trial of recombinant follicle-stimulating hormone pretreatment for GnRH-induced fertility in patients with congenital hypogonadotropic hypogonadism. J Clin Endocrinol Metab (2013) 0.83
Microarray technology offers a novel tool for the diagnosis and identification of therapeutic targets for male infertility. Reproduction (2006) 0.83
Testis morphology in patients with idiopathic hypogonadotropic hypogonadism. Hum Reprod (2006) 0.82
NOTCH signaling in Sertoli cells regulates gonocyte fate. Cell Cycle (2013) 0.81
The spermatogonial stem cell niche in the collared peccary (Tayassu tajacu). Biol Reprod (2012) 0.81
Effect of high intratesticular estrogen on global gene expression and testicular cell number in rats. Reprod Biol Endocrinol (2010) 0.80
Three-dimensional synthetic niche components to control germ cell proliferation. Tissue Eng Part A (2009) 0.79
Identification of a murine testis complementary DNA encoding a homolog to human A-kinase anchoring protein-associated sperm protein. Biol Reprod (2002) 0.78
Establishment and characterization of neonatal mouse sertoli cell lines. J Androl (2003) 0.78
Signaling molecules and pathways regulating the fate of spermatogonial stem cells. Microsc Res Tech (2009) 0.77
Cell-laden hydrogels in integrated microfluidic devices for long-term cell culture and tubulogenesis assays. Small (2013) 0.76
Stem cell potential of the mammalian gonad. Front Biosci (Elite Ed) (2009) 0.75