Published in Development on January 26, 2005
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Myc's broad reach. Genes Dev (2008) 7.56
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Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature (2010) 5.10
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Systematic identification of cis-regulatory sequences active in mouse and human embryonic stem cells. PLoS Genet (2007) 1.77
Long-term magnetic resonance imaging of stem cells in neonatal ischemic injury. Ann Neurol (2010) 1.67
Myc-nick: a cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiation. Cell (2010) 1.67
Mitotic and mitogenic Wnt signalling. EMBO J (2012) 1.62
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An overview of MYC and its interactome. Cold Spring Harb Perspect Med (2014) 1.53
Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin. EMBO J (2006) 1.52
N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor. Cancer Res (2008) 1.52
Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells. J Biol Chem (2010) 1.52
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myc maintains embryonic stem cell pluripotency and self-renewal. Differentiation (2010) 1.50
Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1. EMBO J (2013) 1.50
Unique and overlapping functions of GSK-3 isoforms in cell differentiation and proliferation and cardiovascular development. J Biol Chem (2008) 1.49
Emerging roles of microRNAs in the control of embryonic stem cells and the generation of induced pluripotent stem cells. Dev Biol (2010) 1.47
Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor. EMBO J (2013) 1.46
Role of Src family kinases and N-Myc in spermatogonial stem cell proliferation. Dev Biol (2006) 1.44
Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor. Biochem J (2011) 1.41
The ubiquitous nature of cancer: the role of the SCF(Fbw7) complex in development and transformation. Oncogene (2010) 1.41
Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells. Proc Natl Acad Sci U S A (2006) 1.35
Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus. PLoS One (2008) 1.34
Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts. Oncogene (2011) 1.34
Subcellular localization of glycogen synthase kinase 3beta controls embryonic stem cell self-renewal. Mol Cell Biol (2009) 1.31
Myc regulates the transcription of the PRC2 gene to control the expression of developmental genes in embryonic stem cells. Mol Cell Biol (2011) 1.28
MicroRNAs in embryonic stem cell function and fate. Genes Dev (2010) 1.27
N-Myc regulates expression of pluripotency genes in neuroblastoma including lif, klf2, klf4, and lin28b. PLoS One (2009) 1.23
Competitive interactions eliminate unfit embryonic stem cells at the onset of differentiation. Dev Cell (2013) 1.21
Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc. PLoS One (2009) 1.20
A decade of transcription factor-mediated reprogramming to pluripotency. Nat Rev Mol Cell Biol (2016) 1.16
Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics. Int J Biol Sci (2014) 1.16
Stem cell pluripotency: a cellular trait that depends on transcription factors, chromatin state and a checkpoint deficient cell cycle. J Cell Physiol (2009) 1.13
Technological overview of iPS induction from human adult somatic cells. Curr Gene Ther (2013) 1.13
Determination of protein interactome of transcription factor Sox2 in embryonic stem cells engineered for inducible expression of four reprogramming factors. J Biol Chem (2012) 1.10
Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis. J Transl Med (2015) 1.09
The abbreviated pluripotent cell cycle. J Cell Physiol (2013) 1.09
Mu- and kappa-opioids induce the differentiation of embryonic stem cells to neural progenitors. J Biol Chem (2006) 1.08
Cancer stem cells, cancer cell plasticity and radiation therapy. Semin Cancer Biol (2014) 1.08
Direct targets of Klf5 transcription factor contribute to the maintenance of mouse embryonic stem cell undifferentiated state. BMC Biol (2010) 1.07
Roles for MYC in the establishment and maintenance of pluripotency. Cold Spring Harb Perspect Med (2013) 1.06
Long noncoding RNA MALAT-1 enhances stem cell-like phenotypes in pancreatic cancer cells. Int J Mol Sci (2015) 1.05
Mouse hematopoietic cell-targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging-like phenotype. Blood (2012) 1.05
AMD1 is essential for ESC self-renewal and is translationally down-regulated on differentiation to neural precursor cells. Genes Dev (2012) 1.04
MYC/MAX control ERK signaling and pluripotency by regulation of dual-specificity phosphatases 2 and 7. Genes Dev (2013) 1.04
Manipulation of signaling thresholds in "engineered stem cell niches" identifies design criteria for pluripotent stem cell screens. PLoS One (2009) 1.03
microRNA control of mouse and human pluripotent stem cell behavior. Annu Rev Cell Dev Biol (2013) 1.02
Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains. PLoS One (2012) 1.01
Myc and Miz-1 have coordinate genomic functions including targeting Hox genes in human embryonic stem cells. Epigenetics Chromatin (2011) 1.00
Myc transcription factors: key regulators behind establishment and maintenance of pluripotency. Regen Med (2010) 1.00
Global genomic and proteomic analysis identifies biological pathways related to high-risk neuroblastoma. J Proteome Res (2010) 1.00
Functions of GSK-3 Signaling in Development of the Nervous System. Front Mol Neurosci (2011) 0.99
Zfp281 functions as a transcriptional repressor for pluripotency of mouse embryonic stem cells. Stem Cells (2011) 0.97
c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3. EMBO J (2006) 0.97
Signaling networks in human pluripotent stem cells. Curr Opin Cell Biol (2012) 0.97
The pluripotency-associated gene Dppa4 is dispensable for embryonic stem cell identity and germ cell development but essential for embryogenesis. Mol Cell Biol (2009) 0.97
Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors. Nucleic Acids Res (2011) 0.96
Global levels of H3K27me3 track with differentiation in vivo and are deregulated by MYC in prostate cancer. Am J Pathol (2012) 0.96
A comparative analysis of Müller glia-mediated regeneration in the vertebrate retina. Exp Eye Res (2013) 0.96
Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells. Exp Hematol (2007) 0.95
STAT3 phosphorylation at tyrosine 705 and serine 727 differentially regulates mouse ESC fates. Stem Cells (2014) 0.94
The case for induced pluripotent stem cell-derived cardiomyocytes in pharmacological screening. Br J Pharmacol (2013) 0.94
It's a lipid's world: bioactive lipid metabolism and signaling in neural stem cell differentiation. Neurochem Res (2012) 0.94
Control of vertebrate development by MYC. Cold Spring Harb Perspect Med (2013) 0.94
Myc orchestrates a regulatory network required for the establishment and maintenance of pluripotency. Cell Cycle (2011) 0.94
Regulatory non-coding RNAs in pluripotent stem cells. Int J Mol Sci (2013) 0.93
Stable generation of serum- and feeder-free embryonic stem cell-derived mice with full germline-competency by using a GSK3 specific inhibitor. Genesis (2009) 0.93
Qualitative network modeling of the Myc-p53 control system of cell proliferation and differentiation. Biophys J (2011) 0.93
Proliferation rate of somatic cells affects reprogramming efficiency. J Biol Chem (2013) 0.92
Cdk2: a key regulator of the senescence control function of Myc. Aging (Albany NY) (2010) 0.91
MicroRNAs, stem cells and cancer stem cells. World J Stem Cells (2012) 0.91
Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay. EMBO J (2015) 0.91
Socs3 maintains the specificity of biological responses to cytokine signals during granulocyte and macrophage differentiation. Exp Hematol (2008) 0.91
Frat is a phosphatidylinositol 3-kinase/Akt-regulated determinant of glycogen synthase kinase 3β subcellular localization in pluripotent cells. Mol Cell Biol (2011) 0.91
Metabolic Reprogramming of Stem Cell Epigenetics. Cell Stem Cell (2015) 0.91
Molecular basis of embryonic stem cell self-renewal: from signaling pathways to pluripotency network. Cell Mol Life Sci (2015) 0.90
GSK3 as a Sensor Determining Cell Fate in the Brain. Front Mol Neurosci (2012) 0.90
Troika of the mouse blastocyst: lineage segregation and stem cells. Curr Stem Cell Res Ther (2012) 0.90
Office-based treatment of opiate addiction with a sublingual-tablet formulation of buprenorphine and naloxone. N Engl J Med (2003) 6.94
Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology (2010) 6.40
Architectural protein subclasses shape 3D organization of genomes during lineage commitment. Cell (2013) 6.37
Isolation of patients in single rooms or cohorts to reduce spread of MRSA in intensive-care units: prospective two-centre study. Lancet (2005) 5.01
Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types. Genome Res (2010) 4.67
Parenting intervention in Sure Start services for children at risk of developing conduct disorder: pragmatic randomised controlled trial. BMJ (2007) 3.79
Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis. Genome Res (2009) 3.36
Epigenetic gene promoter methylation at birth is associated with child's later adiposity. Diabetes (2011) 3.18
Pluripotent cell division cycles are driven by ectopic Cdk2, cyclin A/E and E2F activities. Oncogene (2002) 3.06
Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed. Stem Cells (2007) 3.04
Preserving the genetic integrity of human embryonic stem cells. Nat Biotechnol (2005) 3.03
The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming. Cell Stem Cell (2009) 2.72
Cell cycle control of embryonic stem cells. Stem Cell Rev (2005) 2.64
A field test of time-based emergency department quality measures. Ann Emerg Med (2011) 2.06
Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation. Mol Biol Cell (2005) 2.00
Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation. Cell Stem Cell (2012) 1.94
Myc represses primitive endoderm differentiation in pluripotent stem cells. Cell Stem Cell (2010) 1.90
Quality of life in children with heart disease as perceived by children and parents. Pediatrics (2008) 1.72
Characteristics associated with retention among African American and Latino adolescent HIV-positive men: results from the outreach, care, and prevention to engage HIV-seropositive young MSM of color special project of national significance initiative. J Acquir Immune Defic Syndr (2010) 1.58
Wnt signaling and a Smad pathway blockade direct the differentiation of human pluripotent stem cells to multipotent neural crest cells. Proc Natl Acad Sci U S A (2011) 1.56
Glycomics of proteoglycan biosynthesis in murine embryonic stem cell differentiation. J Proteome Res (2007) 1.46
Recruitment of Thr 319-phosphorylated Ndd1p to the FHA domain of Fkh2p requires Clb kinase activity: a mechanism for CLB cluster gene activation. Genes Dev (2003) 1.45
The states' next challenge--securing primary care for expanded Medicaid populations. N Engl J Med (2011) 1.39
Individual budget projects come under the microscope. Ment Health Today (2009) 1.38
Cdk6-cyclin D3 activity in murine ES cells is resistant to inhibition by p16(INK4a). Oncogene (2004) 1.35
Subcellular localization of glycogen synthase kinase 3beta controls embryonic stem cell self-renewal. Mol Cell Biol (2009) 1.31
Productive hepatitis C virus infection of stem cell-derived hepatocytes reveals a critical transition to viral permissiveness during differentiation. PLoS Pathog (2012) 1.29
Linking DNA methyltransferases to epigenetic marks and nucleosome structure genome-wide in human tumor cells. Cell Rep (2012) 1.27
Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs. PLoS Med (2005) 1.26
The IncP-6 plasmid Rms149 consists of a small mobilizable backbone with multiple large insertions. J Bacteriol (2005) 1.22
Early linkage and retention in care: findings from the outreach, linkage, and retention in care initiative among young men of color who have sex with men. AIDS Patient Care STDS (2011) 1.21
Replication timing: a fingerprint for cell identity and pluripotency. PLoS Comput Biol (2011) 1.21
Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum. Infect Immun (2005) 1.18
Factors affecting long-term risk of aortic arch recoarctation after the Norwood procedure. Ann Thorac Surg (2008) 1.17
Human motor neuron differentiation from human embryonic stem cells. Stem Cells Dev (2005) 1.15
IDAWG: Metabolic incorporation of stable isotope labels for quantitative glycomics of cultured cells. J Proteome Res (2009) 1.15
Plasmids from freshwater environments capable of IncQ retrotransfer are diverse and include pQKH54, a new IncP-1 subgroup archetype. Microbiology (2006) 1.14
Changes in nocturia from medical treatment of benign prostatic hyperplasia: secondary analysis of the Department of Veterans Affairs Cooperative Study Trial. J Urol (2003) 1.12
Long-term effectiveness of a parenting intervention for children at risk of developing conduct disorder. Br J Psychiatry (2009) 1.09
Increased abundance of IncP-1beta plasmids and mercury resistance genes in mercury-polluted river sediments: first discovery of IncP-1beta plasmids with a complex mer transposon as the sole accessory element. Appl Environ Microbiol (2006) 1.08
Roles for MYC in the establishment and maintenance of pluripotency. Cold Spring Harb Perspect Med (2013) 1.06
Directed differentiation of human pluripotent cells to neural crest stem cells. Nat Protoc (2013) 1.04
Unintentional injury in preschool boys with and without early onset of disruptive behavior. J Pediatr Psychol (2002) 1.04
MYC/MAX control ERK signaling and pluripotency by regulation of dual-specificity phosphatases 2 and 7. Genes Dev (2013) 1.04
Heparan sulfate facilitates FGF and BMP signaling to drive mesoderm differentiation of mouse embryonic stem cells. J Biol Chem (2012) 1.03
Lectin binding profiles of SSEA-4 enriched, pluripotent human embryonic stem cell surfaces. BMC Dev Biol (2005) 1.03
A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17. J Proteome Res (2012) 1.03
Disease-specific education in the primary care setting increases the knowledge of people with chronic obstructive pulmonary disease: a randomized controlled trial. Patient Educ Couns (2009) 1.02
A randomized feasibility study of a 12-week community-based exercise program for people with Huntington's disease. J Neurol Phys Ther (2013) 1.01
Myc transcription factors: key regulators behind establishment and maintenance of pluripotency. Regen Med (2010) 1.00
Parenting stress and children with heart disease. J Pediatr Health Care (2003) 1.00
Sox2-mediated regulation of adult neural crest precursors and skin repair. Stem Cell Reports (2013) 0.99
Regulation of glycan structures in murine embryonic stem cells: combined transcript profiling of glycan-related genes and glycan structural analysis. J Biol Chem (2012) 0.97
Adult stem cells and mammalian epimorphic regeneration-insights from studying annual renewal of deer antlers. Curr Stem Cell Res Ther (2009) 0.94
Myc orchestrates a regulatory network required for the establishment and maintenance of pluripotency. Cell Cycle (2011) 0.94
Glycoproteomic analysis of embryonic stem cells: identification of potential glycobiomarkers using lectin affinity chromatography of glycopeptides. J Proteome Res (2010) 0.93
Baseline clinical characteristics, antiretroviral therapy use, and viral load suppression among HIV-positive young men of color who have sex with men. AIDS Patient Care STDS (2011) 0.93
Transcriptional profiling of initial differentiation events in human embryonic stem cells. Biochem Biophys Res Commun (2004) 0.93
Sequence of plasmid pBS228 and reconstruction of the IncP-1alpha phylogeny. Plasmid (2007) 0.92
The lectin Dolichos biflorus agglutinin recognizes glycan epitopes on the surface of murine embryonic stem cells: a new tool for characterizing pluripotent cells and early differentiation. Stem Cells (2006) 0.91
Frat is a phosphatidylinositol 3-kinase/Akt-regulated determinant of glycogen synthase kinase 3β subcellular localization in pluripotent cells. Mol Cell Biol (2011) 0.91
Epidemiologic data on young men of color who have sex with men. AIDS Patient Care STDS (2011) 0.90
Double-blind, placebo-controlled trial of selegiline transdermal system (STS) for the treatment of cocaine dependence. Drug Alcohol Depend (2006) 0.90
Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies. J Lipid Res (2009) 0.89
Transmitted HIV-1 drug resistance among young men of color who have sex with men: a multicenter cohort analysis. J Adolesc Health (2010) 0.89
Evaluation of methylation status of the eNOS promoter at birth in relation to childhood bone mineral content. Calcif Tissue Int (2011) 0.89
Linezolid versus teicoplanin in the treatment of Gram-positive infections in the critically ill: a randomized, double-blind, multicentre study. J Antimicrob Chemother (2004) 0.89
Macromolecular crowding amplifies adipogenesis of human bone marrow-derived mesenchymal stem cells by enhancing the pro-adipogenic microenvironment. Tissue Eng Part A (2013) 0.87
Childhood bone mineral content is associated with methylation status of the RXRA promoter at birth. J Bone Miner Res (2014) 0.86
Sequence recognition of alpha-LFA-1-derived peptides by ICAM-1 cell receptors: inhibitors of T-cell adhesion. Chem Biol Drug Des (2007) 0.86
Dietary effects on incretin hormone secretion. Vitam Horm (2010) 0.86
Heparan sulfate: a key regulator of embryonic stem cell fate. Biol Chem (2013) 0.86
Transcriptional profiling of definitive endoderm derived from human embryonic stem cells. Comput Syst Bioinformatics Conf (2007) 0.86
Sustained improvements in peripheral venous catheter care in non-intensive care units: a quasi-experimental controlled study of education and feedback. Infect Control Hosp Epidemiol (2012) 0.84
Serosurveillance for livestock pathogens in free-ranging mule deer (Odocoileus hemionus). PLoS One (2012) 0.84
Reconciling the different roles of Gsk3β in "naïve" and "primed" pluripotent stem cells. Cell Cycle (2012) 0.83
Use of hospitalists and office-based primary care physicians' productivity. J Gen Intern Med (2015) 0.83
Objective patient-related outcomes of rapid-response systems - a pilot study to demonstrate feasibility in two hospitals. Crit Care Resusc (2013) 0.82
Risk of post-operative intravesical mitomycin C instillation following transurethral bladder tumor resection. Can J Urol (2006) 0.81
Provider and care workforce influences on quality of home-care services in England. J Aging Soc Policy (2007) 0.81
Facial appearance and attachment in infants with orofacial clefts: a replication. Cleft Palate Craniofac J (2002) 0.81
The effect of lipid supplements on ruminal bacteria in continuous culture fermenters varies with the fatty acid composition. J Microbiol (2011) 0.80
Lectin-functionalized microchannels for characterizing pluripotent cells and early differentiation. Biomicrofluidics (2012) 0.80
Cellular re- and de-programming by microenvironmental memory: why short TGF-β1 pulses can have long effects. Fibrogenesis Tissue Repair (2013) 0.79
Understanding iron overload: screening, monitoring, and caring for patients with transfusion-dependent anemias. Clin J Oncol Nurs (2009) 0.79
Latent autoimmune diabetes in adults in a South Asian population of the U.K. Diabetes Care (2007) 0.79
Altered cell cycle regulation helps stem-like carcinoma cells resist apoptosis. BMC Biol (2010) 0.78
Idiopathic and Diabetic Gastroparesis. Curr Treat Options Gastroenterol (2003) 0.78
Symptom factors in early-onset psychotic disorders. J Am Acad Child Adolesc Psychiatry (2002) 0.78
N-benzylpiperazine has characteristics of a drug of abuse. Behav Pharmacol (2007) 0.76
Selegiline transdermal system (STS) as an aid for smoking cessation. Nicotine Tob Res (2011) 0.76
Novel methodology to identify TRPV1 antagonists independent of capsaicin activation. J Biomol Screen (2012) 0.76
Epizootic lymphangitis: the impact on subsistence economies and animal welfare. Vet J (2006) 0.76
Trust, standards and healthcare quality: a case of babies and bathwater? J R Soc Med (2006) 0.75
Orlistat augments postprandial increases in glucagon-like peptide-1 in obese type 2 diabetic patients: response to Damci et al. Diabetes Care (2004) 0.75
Modification of a biventricular assist device to facilitate preservative infusion and organ recovery in a nonheart-beating donor. J Extra Corpor Technol (2006) 0.75